ISRN obesity最新文献_第2页

Carotid Intima Media Thickness Is Independently Associated with Male Gender, Middle Age, and IGF-1 in Metabolically Healthy Obese Individuals. 在代谢健康的肥胖个体中，颈动脉内膜中层厚度与男性、中年和IGF-1独立相关。

ISRN obesity Pub Date : 2014-01-28 eCollection Date: 2014-01-01 DOI: 10.1155/2014/545804

Hala Abd El-Hafez, Mohamed M Elrakhawy, Azza A El-Baiomy, Mervat M El-Eshmawy

{"title":"Carotid Intima Media Thickness Is Independently Associated with Male Gender, Middle Age, and IGF-1 in Metabolically Healthy Obese Individuals.","authors":"Hala Abd El-Hafez, Mohamed M Elrakhawy, Azza A El-Baiomy, Mervat M El-Eshmawy","doi":"10.1155/2014/545804","DOIUrl":"https://doi.org/10.1155/2014/545804","url":null,"abstract":"Background/Aims. The effect of benign obesity on subclinical cardiovascular disease is still questionable. The purpose of this study was to assess carotid intima media thickness (CIMT), as a marker of subclinical atherosclerosis, and to evaluate its relation to age, sex, and IGF-1 in metabolically healthy obese (MHO) subjects. Methods. A total of 75 MHO subjects and 80 age, and sex matched healthy nonobese control subjects were included in the study. Body mass index (BMI), waist circumference (WC), blood pressure, fasting plasma glucose, fasting insulin, HOMA-IR, lipid profile, insulin like growth factor-1 (IGF-1), and CIMT were assessed in all subjects. Results. MHO subjects had significantly higher CIMT and lower IGF-1 than healthy nonobese controls. Mean CIMT was significantly higher in MHO men age subgroup range from 30 to 50 years than in their age range matched (premenopausal) MHO women subgroup. In MHO subjects, CIMT was positively correlated with age, BMI, WC, SBP, HOMA-IR, TG, and LDL-C, and negatively correlated with IGF-1. Regression analysis revealed that middle age, male sex and IGF-1 remained independently associated with CIMT in MHO subjects. Conclusion. CIMT is elevated and IGF-1 is reduced in MHO subjects, and CIMT is independently associated with male gender, middle age, and IGF-1. Definition of healthy obesity may be broadened to include IMT measurement. ","PeriodicalId":89786,"journal":{"name":"ISRN obesity","volume":" ","pages":"545804"},"PeriodicalIF":0.0,"publicationDate":"2014-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/545804","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40301020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Downregulation of RelA (p65) by Rapamycin Inhibits Murine Adipocyte Differentiation and Reduces Fat Mass of C57BL/6J Mice despite High Fat Diet. 雷帕霉素下调RelA (p65)抑制小鼠脂肪细胞分化，降低高脂饮食C57BL/6J小鼠脂肪量

ISRN obesity Pub Date : 2014-01-23 eCollection Date: 2014-01-01 DOI: 10.1155/2014/540582

Peter D Ray, Reid A Maclellan, Jin He, Zhigang Liu, Jianguo Wu

{"title":"Downregulation of RelA (p65) by Rapamycin Inhibits Murine Adipocyte Differentiation and Reduces Fat Mass of C57BL/6J Mice despite High Fat Diet.","authors":"Peter D Ray, Reid A Maclellan, Jin He, Zhigang Liu, Jianguo Wu","doi":"10.1155/2014/540582","DOIUrl":"https://doi.org/10.1155/2014/540582","url":null,"abstract":"Rapamycin (RAPA) is a clinical immunosuppressive agent first reported in the literature in 1975 after its discovery in a soil sample from the island of Rapa Nui. Aside from the well-documented effects of RAPA on cell division and immunologic response, the literature reveals it to have negative effects on adipocyte and osteocyte differentiation as well. Understanding of the molecular effects of RAPA on cell differentiation is fragmentary in regard to these cell lineages. In this paper, we examined a potential mechanism for RAPA's effects on adipocyte differentiation in vitro and in vivo. The data point to a unique role of Rel A (p65)-a component of the NF-κB system-in mediating this event. In murine adipose derived stem cell cultures (muADSCs) from C57BL/6J mice, RAPA was found to selectively downregulate RelA/p65, mammalian target of rapamycin (mTOR), and do so in a dose-dependent manner. This implies a novel role for RelA in adipocyte biology. Intracellular lipid accumulation-as subjectively observed-was also decreased in muADSCs treated with RAPA. Mice treated with RAPA had reduced overall body weight and reduced size of both intraabdominal and subcutaneous fat pads. When treated with RAPA, mice fed a high fat diet did not develop obesity and were not different from their regular diet controls in terms of body weight. These results suggested that RAPA inhibits adipogenesis and lipogenesis of muADSCs resulting in a prevention of obesity in C57BL/6J mice. This inhibition is strong enough to negate the effects of a high fat diet and seems to act by downregulating the RelA/p65 mTOR signaling pathway-a key component of the NF-κB family. ","PeriodicalId":89786,"journal":{"name":"ISRN obesity","volume":"2014 ","pages":"540582"},"PeriodicalIF":0.0,"publicationDate":"2014-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/540582","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32168602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Body adiposity index: its relevance and validity in assessing body fatness of adults. 体脂指数在成人体脂评估中的相关性和有效性。

ISRN obesity Pub Date : 2014-01-22 eCollection Date: 2014-01-01 DOI: 10.1155/2014/243294

Shilpi Gupta, Satwanti Kapoor

{"title":"Body adiposity index: its relevance and validity in assessing body fatness of adults.","authors":"Shilpi Gupta, Satwanti Kapoor","doi":"10.1155/2014/243294","DOIUrl":"https://doi.org/10.1155/2014/243294","url":null,"abstract":"Background. One of the limitations of body mass index is its accuracy to assess body fatness. To address this limitation, a new index, body adiposity index, has been developed. However its validity needs to ascertained. Objective. Our aim was to investigate sex-specific relationship between BAI, BMI, and percent body fat in an endogamous population of Delhi, India. Method. Data was collected from 578 adults on bodyweight, height, skinfold thicknesses, hip circumference, waist circumference, and systolic and diastolic blood pressure. Pearson's correlations were calculated for BAI and BMI with PBF. Differences in the correlation coefficients were examined using Fisher's z tests. Receiver operating characteristic analysis was used to compare the predictive validity and to determine optimal cut-off values. Odds ratios were calculated to assess the risk of having hypertension using the proposed cut-off points. Results. The correlations of PBF with BMI (men: r = 0.83; women: r = 0.71) were stronger than those with BAI (men: r = 0.66; women: r = 0.58). In men, the sensitivity and specificity of BAI to predict hypertension were higher than other anthropometric markers but lower than BMI. In women, the sensitivity of BAI was higher than BMI and WC. Conclusions. BAI can be used as an additional marker for screening population; however its validity needs to be demonstrated on other populations too. ","PeriodicalId":89786,"journal":{"name":"ISRN obesity","volume":"2014 ","pages":"243294"},"PeriodicalIF":0.0,"publicationDate":"2014-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/243294","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32168601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 29

Atherosclerosis burden in patients with acute chest pain: obesity paradox. 急性胸痛患者的动脉粥样硬化负担:肥胖悖论。

ISRN obesity Pub Date : 2014-01-12 eCollection Date: 2014-01-01 DOI: 10.1155/2014/634717

Kongkiat Chaikriangkrai, Mahwash Kassi, Sayf Khaleel Bala, Faisal Nabi, Su Min Chang

{"title":"Atherosclerosis burden in patients with acute chest pain: obesity paradox.","authors":"Kongkiat Chaikriangkrai, Mahwash Kassi, Sayf Khaleel Bala, Faisal Nabi, Su Min Chang","doi":"10.1155/2014/634717","DOIUrl":"https://doi.org/10.1155/2014/634717","url":null,"abstract":"Obesity paradox has been described in various populations of coronary artery disease, mainly asymptomatic subjects. However, relationship between obesity and coronary artery calcification detected by cardiac CT in symptomatic patients has rarely been demonstrated. This study seeks to investigate whether the paradoxical relationship between obesity and coronary artery calcification exists in patients with acute chest pain. A final cohort of 1030 chest pain patients presenting at our emergency department who underwent coronary evaluation by multidetector cardiac CT were examined. With absent-to-mild coronary calcification (CAC score < 100) as a referent, multivariable analysis showed that presence of obesity (OR 0.564; 95% CI 0.395, 0.806; P 0.002), body mass index (OR 0.945; 95% CI 0.920, 0.971; P < 0.001), body weight (OR 0.987; 95% CI 0.979, 0.995; P 0.001), and body surface area (OR 0.582; 95% CI 0.369, 0.920; P 0.020) were inversely associated with moderate-to-severe coronary calcification (CAC score ≥ 100). This study extends the concept of obesity paradox to symptomatic patients undergoing coronary artery calcium score assessment. However, biological explanation(s) of this paradox remains unanswered. ","PeriodicalId":89786,"journal":{"name":"ISRN obesity","volume":"2014 ","pages":"634717"},"PeriodicalIF":0.0,"publicationDate":"2014-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/634717","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32140839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Work behind Weight-Loss Surgery: A Qualitative Analysis of Food Intake after the First Two Years Post-Op. 减肥手术背后的工作:术后头两年食物摄入的定性分析。

ISRN obesity Pub Date : 2014-01-09 eCollection Date: 2014-01-01 DOI: 10.1155/2014/427062

Angela A Geraci, Ardith Brunt, Cindy Marihart

{"title":"The Work behind Weight-Loss Surgery: A Qualitative Analysis of Food Intake after the First Two Years Post-Op.","authors":"Angela A Geraci, Ardith Brunt, Cindy Marihart","doi":"10.1155/2014/427062","DOIUrl":"https://doi.org/10.1155/2014/427062","url":null,"abstract":"Purpose. Obesity has reached epidemic proportions in the U.S. and has nearly doubled worldwide since 1980. Bariatric surgery is on the rise, but little focus has been placed on the psychosocial impacts of surgery. The purpose of this study was to explore experiences of patients who have undergone bariatric surgery at least two years before to gain an understanding of the successes and challenges they have faced since surgery. Methods. This study used a phenomenological approach, to investigate the meaning and essence of bariatric patients with food after surgery. Semi-structured interviews were conducted on a sample of nine participants who had undergone surgery at least two years prior. Findings. Two main themes regarding food intake emerged from the data: (a) food after the first year post-surgery and (b) bariatric surgery is not a magic pill. Upon further analysis, food after the first year post-surgery had four subthemes emerge: diet adherence after the first year post-surgery, food intolerances, amount of food, and tendencies toward coping with food do not magically disappear. Conclusion. Findings revealed that post-operative diet and exercise adherence becomes increasingly difficult as weight loss slows. Many participants find that only after the first year after surgery the work really begins. ","PeriodicalId":89786,"journal":{"name":"ISRN obesity","volume":"2014 ","pages":"427062"},"PeriodicalIF":0.0,"publicationDate":"2014-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/427062","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32140838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

Prevalence and Trends of Adult Obesity in the US, 1999-2012. 1999-2012 年美国成人肥胖症的流行率和趋势。

ISRN obesity Pub Date : 2014-01-06 eCollection Date: 2014-01-01 DOI: 10.1155/2014/185132

Ruopeng An

{"title":"Prevalence and Trends of Adult Obesity in the US, 1999-2012.","authors":"Ruopeng An","doi":"10.1155/2014/185132","DOIUrl":"10.1155/2014/185132","url":null,"abstract":"Aim. To provide national estimates of obesity among US adults aged 20 years and older in 2011-2012 and track its trends from 1999 to 2012. Methods. Measured weight/height from National Health and Nutrition Examination Survey 1999-2012 waves was used to calculate body mass index (BMI) and prevalence measures. Piecewise logistic regressions were conducted to test the differential trends before and after 2010. Results. In 2011-2012, the age-adjusted prevalence of overweight and obesity combined (BMI ≥ 25) was 71.1% (95% CI: 68.0%-74.2%) among men and 65.5% (61.8%-69.3%) among women, and the prevalence of obesity (BMI ≥ 30) was 33.3% (30.5%-36.2%) among men and 35.8% (32.3%-39.4%) among women. From 1990-2000 to 2009-2010, the prevalence of overweight and obesity combined, obesity, grades 2 and 3 obesity combined (BMI ≥ 35), and grade 3 obesity (BMI ≥ 40) increased by 7.2%, 17.8%, 17.6%, and 33.0%, respectively. Compared to 2009-2010, most gender- and race/ethnicity-specific prevalence measures remained unchanged or slightly decreased in 2011-2012. No significant difference in trends among prevalence measures was found before and after 2010. Conclusions. Concurrent evidence on the leveling off of obesity in the US is thin. Given its high prevalence and profound socioeconomic consequences, close monitoring of the trend is warranted. ","PeriodicalId":89786,"journal":{"name":"ISRN obesity","volume":"2014 ","pages":"185132"},"PeriodicalIF":0.0,"publicationDate":"2014-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32486349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Youth, caregiver, and prescriber experiences of antipsychotic-related weight gain. 青少年、照顾者和处方医师抗精神病药物相关体重增加的经历。

ISRN obesity Pub Date : 2013-11-20 eCollection Date: 2013-01-01 DOI: 10.1155/2013/390130

Andrea Lynn Murphy, David Martin Gardner, Steve Kisely, Charmaine Cooke, Stanley Paul Kutcher, Jean Hughes

{"title":"Youth, caregiver, and prescriber experiences of antipsychotic-related weight gain.","authors":"Andrea Lynn Murphy, David Martin Gardner, Steve Kisely, Charmaine Cooke, Stanley Paul Kutcher, Jean Hughes","doi":"10.1155/2013/390130","DOIUrl":"https://doi.org/10.1155/2013/390130","url":null,"abstract":"Objectives. To explore the lived experience of youth, caregivers, and prescribers with antipsychotic medications. Design. We conducted a qualitative interpretive phenomenology study. Youth aged 11 to 25 with recent experience taking antipsychotics, the caregivers of youth taking antipsychotics, and the prescribers of antipsychotics were recruited. Subjects. Eighteen youth, 10 caregivers (parents), and 11 prescribers participated. Results. Eleven of 18 youth, six of ten parents, and all prescribers discussed antipsychotic-related weight gain. Participants were attuned to the numeric weight changes usually measured in pounds. Significant discussions occurred around weight changes in the context of body image, adherence and persistence, managing weight increases, and metabolic effects. These concepts were often inextricably linked but maintained the significance as separate issues. Participants discussed tradeoffs regarding the perceived benefits and risks of weight gain, often with uncertainty and inadequate information regarding the short- and long-term consequences. Conclusion. Antipsychotic-related weight gain in youth influences body image and weight management strategies and impacts treatment courses with respect to adherence and persistence. In our study, the experience of monitoring for weight and metabolic changes was primarily reactive in nature. Participants expressed ambiguity regarding the short- and long-term consequences of weight and metabolic changes. ","PeriodicalId":89786,"journal":{"name":"ISRN obesity","volume":"2013 ","pages":"390130"},"PeriodicalIF":0.0,"publicationDate":"2013-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/390130","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32121209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Dietary adherence and satisfaction with a bean-based high-fiber weight loss diet: a pilot study. 基于豆类的高纤维减肥饮食的饮食依从性和满意度:一项试点研究。

ISRN obesity Pub Date : 2013-10-29 eCollection Date: 2013-01-01 DOI: 10.1155/2013/915415

Tonya F Turner, Laura M Nance, William D Strickland, Robert J Malcolm, Susan Pechon, Patrick M O'Neil

{"title":"Dietary adherence and satisfaction with a bean-based high-fiber weight loss diet: a pilot study.","authors":"Tonya F Turner, Laura M Nance, William D Strickland, Robert J Malcolm, Susan Pechon, Patrick M O'Neil","doi":"10.1155/2013/915415","DOIUrl":"https://doi.org/10.1155/2013/915415","url":null,"abstract":"Objective. Dietary fiber can reduce hunger and enhance satiety, but fiber intake during hypocaloric weight loss diets typically falls short of recommended levels. We examined the nutritional effects and acceptability of two high-fiber hypocaloric diets differing in sources of fiber: (a) beans or (b) fruits, vegetables, and whole grains. Methods. Subjects were 2 men, 18 women, mean age = 46.9, and mean BMI = 30.6. Subjects completed 3-day food diaries in each of the two baseline weeks. Subjects were then randomized to four weeks on one of two 1400-calorie diets including 25-35 g fiber primarily from 1.5 cups beans/day or from fruits, vegetables, and whole grains. Recommended fiber-rich foods were provided. Subjects kept weekly 3-day food diaries and were assessed weekly. Results. Diet conditions did not differ on outcome measures. Both diets increased fiber intake from 16.6 g/day (SD = 7.1) at baseline to (treatment average) 28.4 g/day (SD = 6.5) (P < 0.001). Fiber intake was consistent over treatment. Caloric intake dropped from 1623.1 kcal/day (SD = 466.9) (baseline) to 1322.2 kcal/day (SD = 275.8) (P = 0.004). Mean weight loss was 1.4 kg (SD = 1.5; P < 0.001). Energy density and self-reported hunger decreased (P's < 0.01) while self-reported fullness increased (P < 0.05). Both diets were rated as potentially acceptable as long as six months. Conclusions. Both diets significantly increased fiber intake by 75%, increased satiation, and reduced hunger. Results support increasing fiber in weight loss diets with a variety of fiber sources. ","PeriodicalId":89786,"journal":{"name":"ISRN obesity","volume":"2013 ","pages":"915415"},"PeriodicalIF":0.0,"publicationDate":"2013-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/915415","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32142960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Relationship between Birth Weight and Metabolic Status in Obese Adolescents. 肥胖青少年出生体重与代谢状况之间的关系。

ISRN obesity Pub Date : 2013-08-28 eCollection Date: 2013-01-01 DOI: 10.1155/2013/490923

David J Hill, Harry Prapavessis, J Kevin Shoemaker, Michelle Jackman, Farid H Mahmud, Cheril Clarson

{"title":"Relationship between Birth Weight and Metabolic Status in Obese Adolescents.","authors":"David J Hill, Harry Prapavessis, J Kevin Shoemaker, Michelle Jackman, Farid H Mahmud, Cheril Clarson","doi":"10.1155/2013/490923","DOIUrl":"10.1155/2013/490923","url":null,"abstract":"Objective. To examine the relationships between birth weight and body mass index, percent body fat, blood lipids, glycemia, insulin resistance, adipokines, blood pressure, and endothelial function in a cohort of obese adolescents. Design and Methods. Ninety-five subjects aged 10-16 years (mean age 13.5 years) with a body mass index >95th centile (mean [±SEM] 33.0 ± 0.6) were utilized from two prospective studies for obesity prevention prior to any interventions. The mean term birth weight was 3527 ± 64 g (range 1899-4990 g;). Results. Body mass index z-score correlated positively with birth weight (r (2) = 0.05, P = 0.03), but not percent body fat. Insulin resistance negatively correlated with birth weight (r (2) = 0.05, P < 0.001), as did fasting plasma insulin (r (2) = 0.05, P < 0.001); both being significantly greater for subjects of small versus large birth weight (Δ Homeostasis Model Assessment = 2.5 and Δ insulin = 10 pmol/L for birth weight <2.5 kg versus >4.5 kg). Adiponectin, but not leptin, blood pressure z-scores or peripheral arterial tomography values positively correlated with birth weight (r (2) = 0.07, P = 0.008). Conclusions. Excess body mass index in obese adolescents was positively related to birth weight. Birth weight was not associated with cardiovascular risk factors but represented a significant determinant of insulin resistance. ","PeriodicalId":89786,"journal":{"name":"ISRN obesity","volume":"2013 ","pages":"490923"},"PeriodicalIF":0.0,"publicationDate":"2013-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32144102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early Outcomes of Roux-en-Y Gastric Bypass in a Publically Funded Obesity Program. 在一项公共资助的肥胖症计划中，Roux-en-Y 胃旁路术的早期疗效。

ISRN obesity Pub Date : 2013-08-21 eCollection Date: 2013-01-01 DOI: 10.1155/2013/296597

Kevin A Whitlock, Richdeep S Gill, Talal Ali, Xinzhe Shi, Daniel W Birch, Shahzeer Karmali

{"title":"Early Outcomes of Roux-en-Y Gastric Bypass in a Publically Funded Obesity Program.","authors":"Kevin A Whitlock, Richdeep S Gill, Talal Ali, Xinzhe Shi, Daniel W Birch, Shahzeer Karmali","doi":"10.1155/2013/296597","DOIUrl":"10.1155/2013/296597","url":null,"abstract":"Background. There is limited literature assessing the outcomes of bariatric surgery in a publically funded, North American, multidisciplinary bariatric program. Our objective was to assess outcomes of roux-en-Y gastric bypass (RYGB) in a publically funded bariatric program through a retrospective review of patient records. Methods. 293 patients spent a median of 13 months attending a multidisciplinary obesity clinic prior to undergoing laparoscopic RYGB surgery. The hospital was a Canadian, publically funded, level 2 trauma center with university teaching services. Results. 79% of the patients were female and the average BMI at first visit to clinic was 55.3 kg/m2. The average decrease in BMI was 19.2 ± 0.9 kg/m(2). This was an average absolute weight loss of 56.1 kg or 35.5% of initial weight. The average excess weight loss was 63.4 ± 20.4%. Improvement or resolution of obesity related comorbidities occurred in 65.9% of type 2 diabetics and in 50% of hypertensive patients. Conclusion. Despite this being an unconventional setting of a publically funded program in a large Canadian teaching hospital, early outcomes following RYGB were appropriate in severely obese patients. Ongoing work will identify areas of improvement for enhanced efficiencies within this system. ","PeriodicalId":89786,"journal":{"name":"ISRN obesity","volume":"2013 ","pages":"296597"},"PeriodicalIF":0.0,"publicationDate":"2013-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32120834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0