Pancreatic disorders & therapy最新文献_第9页

Double Gastrojejunocolic Fistula as a Late Complication of Pancreatic Head Resection for a Non-Functioning Pancreatic Tumor 双胃空肠结肠瘘作为胰头切除术治疗无功能胰腺肿瘤的晚期并发症

Pancreatic disorders & therapy Pub Date : 2014-11-01 DOI: 10.4172/2165-7092.1000144

R. Pezzilli, F. Ferroni, B. Barakat, L. Calculli

{"title":"Double Gastrojejunocolic Fistula as a Late Complication of Pancreatic Head Resection for a Non-Functioning Pancreatic Tumor","authors":"R. Pezzilli, F. Ferroni, B. Barakat, L. Calculli","doi":"10.4172/2165-7092.1000144","DOIUrl":"https://doi.org/10.4172/2165-7092.1000144","url":null,"abstract":"Pancreatic head resection represents one of the most demanding procedures in abdominal surgery; however, several complications may develop after this type of surgery such as fistulas (internal and/or external), gastrointestinal tract hemorrhage, and abdominal infections. The relaparotomy rate, as well as low perioperative mortality, may be present. The reported postoperative complication rate may range from 23 to 57%, even when an expert surgeon performs the resection. However, late complications of pancreatic head resection are rare. A case of double gastrojejunocolic fistula, which developed in a patient who had undergone pancreatic head resection some years earlier, is herein reported. The patient was admitted to our hospital for abdominal pain associated with nausea andvomiting. She also complained of diarrhea after food ingestion, even in small quantities, and referred the presence of undigested food in the feces and a weight loss of 10 kg in the previous three months. The patient was treated conservatively. We should be aware that symptoms of fistulas due to pancreatic head resections may be diagnosed several years after surgery.","PeriodicalId":89708,"journal":{"name":"Pancreatic disorders & therapy","volume":"21 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76808837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Toxoplasmosis, Pancreatitis, Obesity and Drug Discovery. 弓形虫病，胰腺炎，肥胖和药物发现。

Pancreatic disorders & therapy Pub Date : 2014-09-01

Helieh S Oz

引用次数: 0

Laparoscopic Surgical Treatment of Neuroendocrine Pancreatic Tumors 胰腺神经内分泌肿瘤的腹腔镜手术治疗

Pancreatic disorders & therapy Pub Date : 2014-08-02 DOI: 10.4172/2165-7092.1000E135

V. Fendrich

引用次数: 0

Toxoplasmosis, Pancreatitis, Obesity and Drug Discovery 弓形虫病，胰腺炎，肥胖和药物发现

Pancreatic disorders & therapy Pub Date : 2014-08-01 DOI: 10.4172/2165-7092.1000138

H. Oz

引用次数: 18

Protective effects of Retinoic acid on Streptozotocin-induced Type I Diabetes 视黄酸对链脲佐菌素诱导的I型糖尿病的保护作用

Pancreatic disorders & therapy Pub Date : 2014-07-28 DOI: 10.4172/2165-7092.1000141

E. Molina‐Jijón, Rafael Rodríguez-Muñoz, J. Reyes

引用次数: 3

Can We Prevent the Post-Cholecystectomy Recurrent Pancreatitis? 我们能预防胆囊切除术后胰腺炎复发吗?

Pancreatic disorders & therapy Pub Date : 2014-07-07 DOI: 10.4172/2165-7092.1000140

M. Basile, F. Mazzarulli, G. Martino, V. Resta, R. Lattanzio

{"title":"Can We Prevent the Post-Cholecystectomy Recurrent Pancreatitis?","authors":"M. Basile, F. Mazzarulli, G. Martino, V. Resta, R. Lattanzio","doi":"10.4172/2165-7092.1000140","DOIUrl":"https://doi.org/10.4172/2165-7092.1000140","url":null,"abstract":"Laparoscopic Cholecystectomy is an essential part of treatment of so called pancreatitis. It seems a necessary \u0000but not sufficient therapeutical act as demonstrated by the biliary still high incidence of post-cholecystectomy \u0000pancreatitis. There is no means of knowing which patient affected by biliary pancreatitis with no diagnosable \u0000abnormalities of the biliary main tract will develop a recurrent pancreatitis. This study supports the concept that by \u0000adding a “clearance” of the biliary tact at the cholecystectomy (so called rendezvous technique), a prevention of \u0000recurrent pancreatitis can be obtained. This observational study includes 39 hospitalized patients suffering from an \u0000acute biliary pancreatitis episode. None of them had serum bilirubin elevation or jaundice, and 27 had no \u0000instrumental evidence of bile duct obstruction while 12 had minor stones in the main bile duct. Rendezvous \u0000technique revealed undiagnosed bile duct abnormalities either functional or organic in 13 cases. During a 5 years \u0000follow-up period after the procedure no recurrent pancreatitis were observed. Our experience has shown that the \u0000technique of Rendezvous can reveal and treat obstructions of the bile duct that have not been diagnosed with \u0000instrumental examinations; furthermore, this technique seems to prevent the development of recurrent acute \u0000pancreatitis.","PeriodicalId":89708,"journal":{"name":"Pancreatic disorders & therapy","volume":"35 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2014-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80682902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Histopathological Aspects of Pancreatic Metastases in Renal Cell Carcinoma: Does the Mode of Invasion Permit Limited Resections? 肾细胞癌胰腺转移的组织病理学方面:浸润方式是否允许有限的切除?

Pancreatic disorders & therapy Pub Date : 2014-06-14 DOI: 10.4172/2165-7092.1000136

Y. Kimura, Yoshiko Keira, M. Imamura, Tatsuya Ito, T. Nobuoka, T. Mizuguchi, N. Masumori, T. Hasegawa, K. Hirata

{"title":"Histopathological Aspects of Pancreatic Metastases in Renal Cell Carcinoma: Does the Mode of Invasion Permit Limited Resections?","authors":"Y. Kimura, Yoshiko Keira, M. Imamura, Tatsuya Ito, T. Nobuoka, T. Mizuguchi, N. Masumori, T. Hasegawa, K. Hirata","doi":"10.4172/2165-7092.1000136","DOIUrl":"https://doi.org/10.4172/2165-7092.1000136","url":null,"abstract":"Purpose: To investigate histopathological characteristics, we retrospectively analyzed data from patients who underwent resection of renal cell carcinoma pancreatic metastases (RCC-PMs). Methods: This study included 34 RCC-PM lesions in 13 patients who underwent 15 pancreatic operations. The clinicopathlogical characteristics were analyzed with special emphasis on tumor capsular formation, manner of peritumoral invasion, and presence of lymphovascular invasion. Results: Median duration to onset of RCC-PMs was 101 months from initial nephrectomy. Surgical procedures included distal pancreatectomy in 6 cases, pancreaticoduodenectomy in 4, total pancreatectomy in 1, and limited resections in 6 with two overlapping procedures. No perioperative deaths were encountered. One, three, and five year survival rates after pancreatic resection were 86.2%, 86.2%, and 76.6%, respectively. Of thirty- four lesions 32 lesions with tumor diameter ≤ 35 mm were encapsulated. Of these 32 lesions with capsule formation, extra capsular invasion was identified in 5 lesions. No lymphatic invasion was identified in any case. Venous invasion was presented just adjacent to the tumors in 2 lesions. Five year survival rates for the 11 cases with standard operations and 4 cases with limited resection were 70.7% and 100%, respectively without any significant difference. Conclusions: Small RCC-PMs were frequently encapsulated, seldom invaded into pancreatic parenchyma, and were rarely accompanied by microscopic lymph vascular invasion. Limited resection of the pancreas with adequate surgical margins may be oncologically acceptable.","PeriodicalId":89708,"journal":{"name":"Pancreatic disorders & therapy","volume":"10 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2014-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87657170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Pancreas Transplantation with Systemic-Enteric Drainage when Portal-Enteric Drainage is Contraindicated 当门静脉-肠内引流是禁忌时，采用系统-肠内引流的胰腺移植

Pancreatic disorders & therapy Pub Date : 2014-06-08 DOI: 10.4172/2165-7092.1000134

R. Stratta, A. Farney, Orl, U. Farooq, Y. al-Shraideh, H. El-Hennawy, J. Rogers

引用次数: 2

Appropriate Search of the Etiologies of Acute Pancreatitis 急性胰腺炎病因的适当搜索

Pancreatic disorders & therapy Pub Date : 2014-06-08 DOI: 10.4172/2165-7092.1000135

S. Pongprasobchai

引用次数: 0

Complications of Type 1 Diabetes Mellitus are Associated with Renin Angiotensin System: The Role of Physical Exercise as Therapeutic Tool 1型糖尿病并发症与肾素血管紧张素系统相关:体育锻炼作为治疗工具的作用

Pancreatic disorders & therapy Pub Date : 2014-06-05 DOI: 10.4172/2165-7092.1000133

P. Fiorino, F. Evangelista

{"title":"Complications of Type 1 Diabetes Mellitus are Associated with Renin Angiotensin System: The Role of Physical Exercise as Therapeutic Tool","authors":"P. Fiorino, F. Evangelista","doi":"10.4172/2165-7092.1000133","DOIUrl":"https://doi.org/10.4172/2165-7092.1000133","url":null,"abstract":"Type 1 diabetes mellitus (T1DM) is associated with the development of severe complications including \u0000cardiovascular diseases, nephropathy, retinopathy and neuropathy. The peptide Angiotensin II (Ang II), the main \u0000effector molecule of the renin angiotensin system (RAS), has been widely investigated because it plays an important \u0000role in the pathogenesis of T1DM and evidence in the literature suggests the pharmacological blockade of the RAS \u0000components as a potential therapeutic strategy to minimize the deleterious effects of T1DM by improving \u0000metabolism control, renal and cardiovascular functions.Physical exercise can also contribute to avoid the \u0000complications of T1DM by enhancing metabolism of carbohydrates and lipids, peak oxygen consumption, vascular \u0000function, autonomic response and arterial blood pressure. Furthermore, the physical exercise is able to reduce the \u0000level of tissue RAS. Thus, part of the benefits of physical exercise for prevention and treatment of metabolic and \u0000 cardiovascular diseases in T1DM may be mediated by the RAS. The present review aimed to discuss the evidence \u0000regarding the involvement of the RAS in the progression of T1DM, the relevance of physical exercise to the \u0000management of T1DM and the role of physical exercise to induce adaptations in the RAS.","PeriodicalId":89708,"journal":{"name":"Pancreatic disorders & therapy","volume":"20 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2014-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78805633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15