Case reports in nephrology and urology最新文献_第2页

Pulmonary toxicity in a renal transplant recipient treated with amiodarone and everolimus: a case of hypothetical synergy and a proposal for a screening protocol. 胺碘酮和依维莫司治疗肾移植受者的肺毒性:一个假设的协同作用和筛选方案的建议。

Case reports in nephrology and urology Pub Date : 2014-04-12 eCollection Date: 2014-01-01 DOI: 10.1159/000362361

Alberto Mella, Maria Messina, Andrea Ranghino, Paolo Solidoro, Giuseppe Tabbia, Giuseppe Paolo Segoloni, Luigi Biancone

{"title":"Pulmonary toxicity in a renal transplant recipient treated with amiodarone and everolimus: a case of hypothetical synergy and a proposal for a screening protocol.","authors":"Alberto Mella, Maria Messina, Andrea Ranghino, Paolo Solidoro, Giuseppe Tabbia, Giuseppe Paolo Segoloni, Luigi Biancone","doi":"10.1159/000362361","DOIUrl":"https://doi.org/10.1159/000362361","url":null,"abstract":"Pneumotoxic drugs like amiodarone and m-TOR inhibitors (m-TORi) may be administered contemporaneously in therapy for patients who had renal transplants. We present a case of amiodarone pulmonary toxicity (APT) in a patient treated with amiodarone and everolimus. A 57-year-old Caucasian male, under treatment with both everolimus (for 3 years) and amiodarone (for 2 months), presented with fever, dyspnoea and a negative chest X-ray after his second kidney transplant with suboptimal serum creatinine (3 mg/dl). A non-contrastive high-resolution CT scan showed bilateral interstitial lung disease with an associated reduction in carbon monoxide diffusing capacity. Bronchoalveolar lavage (BAL) was negative for an infection, but BAL cytology was suitable for APT (50% of 'foamy' macrophages). A complete recovery was achieved after amiodarone interruption and an oral steroid therapy increase. Everolimus was continued. His kidney function remained unchanged in the upcoming months. In conclusion, we suggest a possible synergistic effect between m-TORi and amiodarone. Furthermore, we propose a diagnostic algorithm that can be used as a surveillance tool to identify a potential initial lung damage in patients treated with 1 or more pneumotoxic drugs. ","PeriodicalId":89663,"journal":{"name":"Case reports in nephrology and urology","volume":"4 1","pages":"75-81"},"PeriodicalIF":0.0,"publicationDate":"2014-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000362361","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32358327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Malignant solitary fibrous kidney tumor with peritoneal disease: a case report. 伴有腹膜疾病的恶性单发纤维性肾肿瘤：病例报告。

Case reports in nephrology and urology Pub Date : 2014-04-11 eCollection Date: 2014-01-01 DOI: 10.1159/000362539

Maria Isabel Rodríguez Cruz, Jose Emilio Hernández Sánchez, Beatriz Segovia Blázquez, Sara Belen Prieto Nogal, Luis Miguel Gómez Tejeda

引用次数: 0

A Case of Membranous Glomerulonephropathy Associated with Takayasu's Arteritis. 膜性肾小球肾病伴高松动脉炎1例。

Case reports in nephrology and urology Pub Date : 2014-04-01 eCollection Date: 2014-01-01 DOI: 10.1159/000360850

Ryo Koda, Atsunori Yoshino, Yuji Imanishi, Shinya Kawamoto, Yoshihiko Ueda, Junichiro James Kazama, Ichiei Narita, Tetsuro Takeda

{"title":"A Case of Membranous Glomerulonephropathy Associated with Takayasu's Arteritis.","authors":"Ryo Koda, Atsunori Yoshino, Yuji Imanishi, Shinya Kawamoto, Yoshihiko Ueda, Junichiro James Kazama, Ichiei Narita, Tetsuro Takeda","doi":"10.1159/000360850","DOIUrl":"https://doi.org/10.1159/000360850","url":null,"abstract":"Glomerulonephropathy is a rare complication of Takayasu's arteritis (TA). To date, most glomerulonephropathies associated with TA show the histological feature of mesangial proliferation. Membranous glomerulonephropathy (MG) is a form of glomerulonephropathy in which the mesangial proliferation is not conspicuous and its association with TA is extremely rare. A 54-year-old man was referred to our hospital due to progressive edema in the lower limbs and nephrotic range proteinuria. Five years previously, he underwent percutaneous angioplasty for left subclavian artery stenosis. Kidney biopsy revealed stage II MG. General examination including enhanced CT scan confirmed the presence of TA. He started oral prednisolone therapy at a dose of 40 mg daily. The C-reactive protein level normalized 7 days after the prednisolone therapy. Three months later, proteinuria had remitted. Though the true relationship between MG and TA was not revealed in present case, considering the fact that complete remission of nephrotic syndrome occurred following the improvement of C-reactive protein level in response to steroid therapy, TA might be the secondary cause of MG. To our best knowledge, only two case reports described the association of MG and TA previously. Those two patients, however, also demonstrated the feature of systemic lupus erythematosus in addition to TA. This is the first case report that describes a patient who presented as MG associated with TA, but not complicated by systemic lupus erythematosus. ","PeriodicalId":89663,"journal":{"name":"Case reports in nephrology and urology","volume":"4 1","pages":"60-9"},"PeriodicalIF":0.0,"publicationDate":"2014-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000360850","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32358326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

A case of bladder cancer after radiation therapy for prostate cancer. 前列腺癌放射治疗后膀胱癌1例。

Case reports in nephrology and urology Pub Date : 2014-03-27 eCollection Date: 2014-01-01 DOI: 10.1159/000361013

Naoto Kaburaki, Takeo Kosaka, Satoshi Yazawa, Mototsugu Oya

引用次数: 1

Carotid thromboembolism associated with nephrotic syndrome treated with dabigatran. 达比加群治疗与肾病综合征相关的颈动脉血栓栓塞。

Case reports in nephrology and urology Pub Date : 2014-03-21 eCollection Date: 2014-01-01 DOI: 10.1159/000362162

Yosuke Sasaki, Yoshihiko Raita, Genta Uehara, Yasushi Higa, Hitoshi Miyasato

{"title":"Carotid thromboembolism associated with nephrotic syndrome treated with dabigatran.","authors":"Yosuke Sasaki, Yoshihiko Raita, Genta Uehara, Yasushi Higa, Hitoshi Miyasato","doi":"10.1159/000362162","DOIUrl":"https://doi.org/10.1159/000362162","url":null,"abstract":"Nephrotic syndrome (NS) may be complicated by thromboembolism, which occasionally manifests as stroke. Although the optimal, standardized approach to the prophylaxis and management of thromboembolic complications associated with NS has not been established, anticoagulation with heparin and subsequent warfarin is the de facto standard of treatment. Dabigatran, a novel direct thrombin inhibitor, has become a substitute for warfarin and heparin for many indications, including the prophylaxis of stroke associated with nonvalvular atrial fibrillation and postoperative thromboprophylaxis in orthopedic patients. We report a 35-year-old male with NS due to membranous nephropathy (MN) that presented with carotid thromboembolism. Because the patient developed drug-induced hepatitis due to warfarin, we attempted treatment with dabigatran and were successful in continuing the medication without any complications. We also reviewed the literature on stroke associated with NS. Twenty-one prior cases have been reported, and the review of these cases revealed some interesting points. The age of onset ranged from 19 to 59 years. Most of the reported cases sustained a stroke at earlier ages than patients with atherosclerosis and atrial fibrillation, which suggests that NS may independently predispose individuals to arterial and venous thromboses. MN was the most common underlying pathology. Given that a standardized approach to the prophylaxis and management of thrombotic complications associated with NS has not been established, our experience suggests that dabigatran is a valid new treatment option for thrombotic complications of NS. ","PeriodicalId":89663,"journal":{"name":"Case reports in nephrology and urology","volume":"4 1","pages":"42-52"},"PeriodicalIF":0.0,"publicationDate":"2014-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000362162","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32320747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Immunoadsorption: a new strategy to induce remission in membranous lupus nephritis. 免疫吸附:诱导膜性狼疮性肾炎缓解的新策略。

Case reports in nephrology and urology Pub Date : 2014-03-19 eCollection Date: 2014-01-01 DOI: 10.1159/000361014

Tim Ulinski, Aurélie Davourie-Salandre, Isabelle Brocheriou, Bilal Aoun

{"title":"Immunoadsorption: a new strategy to induce remission in membranous lupus nephritis.","authors":"Tim Ulinski, Aurélie Davourie-Salandre, Isabelle Brocheriou, Bilal Aoun","doi":"10.1159/000361014","DOIUrl":"https://doi.org/10.1159/000361014","url":null,"abstract":"We report the case of an 11-year-old previously healthy girl who presented for microscopic hematuria and nephrotic proteinuria with normal renal function, which persisted after 6 months of steroids, angiotensin-converting enzyme inhibitors (ACEi)/angiotensin receptor blockers, hydroxychloroquine, mycophenolic acid and a low-salt diet. A serum investigation suggested lupus nephritis and a renal biopsy, performed 2 weeks after the first proteinuria detection, revealed membranous lupus nephritis. We decided to perform ten sessions of daily immunoadsorption. Proteinuria decreased significantly over these ten sessions from 8 to 0.12 g/l. After the tenth immunoadsorption session, the patient received the first rituximab (RTX) infusion leading to complete B-cell depletion. The patient was maintained on ACEi associated with mycophenolic acid and hydroxychloroquine. Three RTX reinjections were performed when CD19-positive cells reappeared in peripheral blood. Despite complete B-cell recovery and positive anti-dsDNA-Ab, the patient remained in complete remission 18 months after the initial diagnosis with negative proteinuria and a normal renal function. ","PeriodicalId":89663,"journal":{"name":"Case reports in nephrology and urology","volume":"4 1","pages":"37-41"},"PeriodicalIF":0.0,"publicationDate":"2014-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000361014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32320746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

IgA Nephropathy with Pathologic Features of Membranoproliferative Glomerulonephritis following Burn Injury. 烧伤后IgA肾病伴膜增生性肾小球肾炎的病理特征。

Case reports in nephrology and urology Pub Date : 2014-03-06 eCollection Date: 2014-01-01 DOI: 10.1159/000360523

Jili Zhu, Huiming Wang, Dingping Yang

引用次数: 4

Hemodialysis without Anticoagulation for a Patient with Chronic Disseminated Intravascular Coagulation. 慢性弥散性血管内凝血患者不加抗凝的血液透析治疗。

Case reports in nephrology and urology Pub Date : 2014-02-18 eCollection Date: 2014-01-01 DOI: 10.1159/000358269

Masayuki Yamanouchi, Yoshifumi Ubara, Koki Mise, Noriko Hayami, Rikako Hiramatsu, Keiichi Sumida, Tatsuya Suwabe, Eiko Hasegawa, Junichi Hoshino, Naoki Sawa, Fumi Takemoto, Kenmei Takaichi

{"title":"Hemodialysis without Anticoagulation for a Patient with Chronic Disseminated Intravascular Coagulation.","authors":"Masayuki Yamanouchi, Yoshifumi Ubara, Koki Mise, Noriko Hayami, Rikako Hiramatsu, Keiichi Sumida, Tatsuya Suwabe, Eiko Hasegawa, Junichi Hoshino, Naoki Sawa, Fumi Takemoto, Kenmei Takaichi","doi":"10.1159/000358269","DOIUrl":"https://doi.org/10.1159/000358269","url":null,"abstract":"We report a 68-year-old Japanese man with end-stage renal failure requiring hemodialysis and chronic disseminated intravascular coagulation (DIC) related to thrombosis in an aortic aneurysm. He had undergone graft replacement for the dissection of the ascending and descending thoracic aorta in 1990 and 2002, respectively. Computed tomography disclosed an aneurysm with thrombosis in the residual aorta adjacent to the graft anastomosis. DIC was diagnosed based on elevation of serum fibrinogen degradation products while his activated partial thromboplastin time, prothrombin time and fibrinogen level were normal. In 2008, hemodialysis was initiated for end-stage renal failure. Dialysis was performed without administration of an anticoagulant because his activated clotting time (ACT) was prolonged to 150-180 s. Thereafter, stable hemodialysis continued without clotting in the dialysis circuit until 2013. If monitoring of ACT can be done, hemodialysis without anticoagulation may be a therapeutic option in such patients. ","PeriodicalId":89663,"journal":{"name":"Case reports in nephrology and urology","volume":"4 1","pages":"25-30"},"PeriodicalIF":0.0,"publicationDate":"2014-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000358269","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32240713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The use of lanreotide in polycystic kidney disease: a single-centre experience. lanreotide在多囊肾病中的应用:单中心经验

Case reports in nephrology and urology Pub Date : 2014-02-05 eCollection Date: 2014-01-01 DOI: 10.1159/000358268

S Treille, J M Bailly, J Van Cauter, F Dehout, B Guillaume

引用次数: 5

Revision of perineal urethrostomy using a meshed split-thickness skin graft. 会阴尿道造口术的改良。

Case reports in nephrology and urology Pub Date : 2014-01-30 eCollection Date: 2014-01-01 DOI: 10.1159/000358556

N Lumen, P Houtmeyers, S Monstrey, A-F Spinoit, W Oosterlinck, P Hoebeke

引用次数: 10