Open journal of neuroscience最新文献

筛选
英文 中文
Patterns of olivocochlear axonal branches. 耳蜗轴突分支的形态。
Open journal of neuroscience Pub Date : 2011-10-12
Amar U Kishan, Charles C Lee, Jeffery A Winer
{"title":"Patterns of olivocochlear axonal branches.","authors":"Amar U Kishan, Charles C Lee, Jeffery A Winer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The olivocochlear (OC) pathway is the source of major feedback control of ascending acoustic information. Two main patterns of axonal branching are evident at this and other levels of the auditory pathway: long-distance collaterals and branches involved in feedback-control loops. Only a minority of OC neurons project to both cochlea, consistent with a role for the system in sound localization. OC branches to the ventral cochlear nucleus provide the anatomical substrate for a feedback control loop that could aid in modulating the intensity of acoustic information being conveyed to higher cortical levels while still dampening the overall intensity of signaling from the cochlea itself.</p>","PeriodicalId":89610,"journal":{"name":"Open journal of neuroscience","volume":"1 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2011-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279734/pdf/nihms337334.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30472183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lesion of the Subfornical Organ attenuates Neuronal Activation of the Paraventricular Nucleus in response to Angiotensin II in normal rats. 皮层下器官病变减弱了正常大鼠室旁核对血管紧张素II的神经元激活。
Open journal of neuroscience Pub Date : 2011-09-23
Jessica Meehan, John P Collister
{"title":"Lesion of the Subfornical Organ attenuates Neuronal Activation of the Paraventricular Nucleus in response to Angiotensin II in normal rats.","authors":"Jessica Meehan, John P Collister","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction/hypothesis: </strong>The subfornical organ, one of the central circumventricular organs, has been shown to mediate many of the effects of circulating angiotensin II (AngII). Where these signals are processed downstream is not fully understood. The SFO does indeed project to prominent cardiovascular regulatory centers such as the paraventricular nucleus (PVN), of whose neurons are activated by central AngII. We reasoned that AngII sensed at the SFO would cause neuronal activation at downstream hypothalamic areas such as the median preoptic nucleus and paraventricular nucleus, and as such would be diminished in animals with lesions of the SFO.</p><p><strong>Materials and methods: </strong>To test this hypothesis, groups of rats underwent either SFO lesion (SFOx) or sham operation. Five days later rats were instrumented with radiotelemetry transducers for monitoring of mean arterial pressure (MAP) and venous catheters for infusions. MAP and heart rate were measured continuously. After a 4 day control period, infusion of AngII (0.575 µg/kg/min) was begun for a period of 2 hours. Rats were then sacrificed and brains were processed for neuronal Fos expression.</p><p><strong>Results: </strong>AngII produced Fos expression in the SFO, MnPO and PVN of sham rats. Fos expression was greatly attenuated in the PVN of SFOx rats.</p><p><strong>Conclusion: </strong>These results support our hypothesis, suggesting that AngII sensitive neurons of the SFO can mediate neuronal activation in the PVN.</p>","PeriodicalId":89610,"journal":{"name":"Open journal of neuroscience","volume":"1 ","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2011-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008144/pdf/nihms329883.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32313089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书