Neuroembryology and aging最新文献

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Effect of the Ethnic Factor on Cranial Capacity and Brain Weight of Male Newborns in Northern Iran 民族因素对伊朗北部男性新生儿颅脑容量和脑重的影响
Neuroembryology and aging Pub Date : 2004-07-01 DOI: 10.1159/000094603
M. Golalipour, K. Heydari
{"title":"Effect of the Ethnic Factor on Cranial Capacity and Brain Weight of Male Newborns in Northern Iran","authors":"M. Golalipour, K. Heydari","doi":"10.1159/000094603","DOIUrl":"https://doi.org/10.1159/000094603","url":null,"abstract":"Brain weight and cranial capacity are useful in evaluating the health of newborns and providing a baseline to study the changes that might occur to the cranium in later years of life. A total of 419 normal male newborns were evaluated by classic cephalometry. The cranial capacities in the native Fars (n = 203) and Turkman (n = 216) groups were 599 ± 30 and 590 ± 30 ml, respectively (p < 0.05), and brain weights in these two groups were 619.9 ± 34 and 610.8 ± 31 g (p < 0.05). Therefore, an ethnic factor might influence brain weight and the cranial capacity of newborns.","PeriodicalId":89607,"journal":{"name":"Neuroembryology and aging","volume":"3 1","pages":"146 - 148"},"PeriodicalIF":0.0,"publicationDate":"2004-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000094603","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64346157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
The Inferior Colliculus: A Center for Convergence of Ascending and Descending Auditory Information 下丘:上升和下降听觉信息汇聚的中心
Neuroembryology and aging Pub Date : 2004-07-01 DOI: 10.1159/000096799
M. Malmierca
{"title":"The Inferior Colliculus: A Center for Convergence of Ascending and Descending Auditory Information","authors":"M. Malmierca","doi":"10.1159/000096799","DOIUrl":"https://doi.org/10.1159/000096799","url":null,"abstract":"A major goal in auditory research is to understand completely how we hear, the physiology of the human auditory system and to identify the causes and treatments for hearing impairment. By understanding all the elements of the ‘auditory scaffold’ we will begin to achieve these important goals. The inferior colliculus (IC) occupies a strategic position in the central auditory system and may be considered a central hub or an interface between the lower auditory pathway, the auditory cortex and motor systems. The IC is the site for termination of the ascending fibers of the lateral lemniscus and also receives a heavy innervation from the auditory cortex. Furthermore, the IC receives crossed projections from its counterpart and possesses a dense network of local connections. Thus, the IC is the main site of auditory integration at the midbrain level. Anatomical and physiological experiments demonstrate that the IC is involved in a great diversity of functional roles in the auditory system, and that most of the interesting auditory features might already be extracted from incoming sounds by this midbrain nucleus.","PeriodicalId":89607,"journal":{"name":"Neuroembryology and aging","volume":"3 1","pages":"215 - 229"},"PeriodicalIF":0.0,"publicationDate":"2004-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000096799","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64365868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 43
Degeneration in the Brains of Parkinson’s Disease Patients 帕金森氏症患者的大脑退化
Neuroembryology and aging Pub Date : 2004-07-01 DOI: 10.1159/000094553
Lihong Zhang, Mingwei Wang, Qi Li, D. Yew, Lucille T. Wolff
{"title":"Degeneration in the Brains of Parkinson’s Disease Patients","authors":"Lihong Zhang, Mingwei Wang, Qi Li, D. Yew, Lucille T. Wolff","doi":"10.1159/000094553","DOIUrl":"https://doi.org/10.1159/000094553","url":null,"abstract":"Parkinson’s disease is a progressive neurodegenerative disease associated with the loss of the dopaminergic nigrostriatal tract in the basal ganglia. In the present study, we examined Parkinson’s disease-related degeneration that includes but is not limited to the basal ganglia. T1-weighted MRI scans of Parkinson’s disease patients were employed. We found additional atrophy outside of the basal ganglia in 93% of the patients. Our results suggest that future studies should be done to determine how this additional atrophy relates to current pathological models of Parkinson’s disease.","PeriodicalId":89607,"journal":{"name":"Neuroembryology and aging","volume":"3 1","pages":"111 - 114"},"PeriodicalIF":0.0,"publicationDate":"2004-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000094553","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64344925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arnold-Chiari Syndrome (Type I) Arnold-Chiari综合征(I型)
Neuroembryology and aging Pub Date : 2004-07-01 DOI: 10.1159/000094671
N. Taşdemir, O. Tacar, A. Demirant, Serhan Tasdemir
{"title":"Arnold-Chiari Syndrome (Type I)","authors":"N. Taşdemir, O. Tacar, A. Demirant, Serhan Tasdemir","doi":"10.1159/000094671","DOIUrl":"https://doi.org/10.1159/000094671","url":null,"abstract":"Arnold-Chiari syndrome is a rare malformation of the brain that is generally present from birth. This type of brain malformation may be associated with other anomalies including hydrocephalus, myelomeningocele, syringomyelia and spina bifida. There are 3 types of Arnold-Chiari malformation (types I, II and III). The clinical symptoms of all 3 types include torticollis, opisthotonus, headache, vertigo, vocal cord paralysis, apnea, nystagmus, dysphagia and ataxia. The Chiari I malformation is considered to be congenital, although there have been reported cases of an acquired form. The incidence of this malformation has been found to be ∼0.56% via magnetic resonance imaging (MRI) studies. The malformation is characterized by a displacement of the cerebellar tonsils, medulla and the fourth ventricle into the spinal canal. The diagnosis can be difficult because not all patients present the classical symptoms of herniated tonsils. However, this anomaly may be diagnosed with MRI. Here we describe a case study of a 22-year-old female patient in a neurology clinic complaining of both headache and vertigo. We determined via MRI that there was a hernia of the cerebellar tonsillar located inferiorly to the foramen magnum. On the other hand the width of the fourth ventricle and the parenchyma tissue of the cerebellum were normal. This type of malformation may prove to be the cause of headache and vertigo in some people. MRI may therefore be a useful tool to aid in the accurate diagnosis of their symptoms.","PeriodicalId":89607,"journal":{"name":"Neuroembryology and aging","volume":"3 1","pages":"149 - 151"},"PeriodicalIF":0.0,"publicationDate":"2004-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000094671","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64346272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
From Receptive Field Dynamics to the Rate of Transmitted Information: Some Facets of the Thalamocortical Auditory System 从感受野动力学到传递信息的速率:丘脑皮质听觉系统的某些方面
Neuroembryology and aging Pub Date : 2004-07-01 DOI: 10.1159/000096800
C. Huetz, J. Edeline
{"title":"From Receptive Field Dynamics to the Rate of Transmitted Information: Some Facets of the Thalamocortical Auditory System","authors":"C. Huetz, J. Edeline","doi":"10.1159/000096800","DOIUrl":"https://doi.org/10.1159/000096800","url":null,"abstract":"In this article, we first evaluate the literature describing reorganizations of auditory cortex topography after behavioral training. We then review the studies showing that receptive fields of auditory thalamocortical neurons express large dynamics in unanesthetized animals. During the time course of different behavioral training protocols, the frequency tuning curves of thalamocortical neurons can be selectively modified to code for the learned importance of acoustic stimuli. In other circumstances, when the vigilance state shifts from waking to sleep, the functional properties of thalamic and cortical neurons exhibit drastic modifications. Finally, we point out new lines of research. First, investigations describing the responses of neurons to communication signals (e.g. species-specific vocalizations) are important because they reveal how the thalamocortical auditory system processes biologically relevant sounds. Second, we suggest that the spike timing precision can largely increase the amount of information transmitted in the thalamocortical auditory system. This urges for more systematic studies in which the temporal organization of spike trains will be considered at presentation of natural stimuli.","PeriodicalId":89607,"journal":{"name":"Neuroembryology and aging","volume":"3 1","pages":"230 - 238"},"PeriodicalIF":0.0,"publicationDate":"2004-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000096800","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64365929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Toward Maturation of the Vestibular System: Neural Circuits and Neuronal Properties 前庭系统走向成熟:神经回路和神经元特性
Neuroembryology and aging Pub Date : 2004-07-01 DOI: 10.1159/000096794
C. Lai, Y. Tse, D. Shum, Y. Chan
{"title":"Toward Maturation of the Vestibular System: Neural Circuits and Neuronal Properties","authors":"C. Lai, Y. Tse, D. Shum, Y. Chan","doi":"10.1159/000096794","DOIUrl":"https://doi.org/10.1159/000096794","url":null,"abstract":"This review focuses on efforts to unravel conundrums on the development of the vestibular system. In the first section, maturation of the peripheral vestibular system and the involvement of transcription factors in the patterning of peripheral vestibular components are highlighted. Cell surface and matrix molecules have also been implicated in fasciculation and guidance of axons in the course of vestibular circuit formation. In rodents, the central vestibular neurons continue to develop after birth until they reach maturity in morphology and function. Sequential maturation of neuronal subpopulations within the developing network of the horizontal and vertical otolith systems is also presented. In another section, the expression pattern of glutamate receptor subunits within the developing vestibular nuclear complex is reviewed in relation to their potential role in regulating postnatal function of the vestibular system. Lastly, postnatal changes in the properties of vestibular nuclear neurons and their capability in coding head movement information appear to prime the development of vestibular-related motor functions.","PeriodicalId":89607,"journal":{"name":"Neuroembryology and aging","volume":"563 1","pages":"162 - 170"},"PeriodicalIF":0.0,"publicationDate":"2004-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000096794","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64365890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do Olfactory Ensheathing Cells Play a Role in the Defense of the Brain against Infection? 嗅鞘细胞在大脑防御感染中起作用吗?
Neuroembryology and aging Pub Date : 2004-07-01 DOI: 10.1159/000094557
M. Chuah, A. Vincent, A. West
{"title":"Do Olfactory Ensheathing Cells Play a Role in the Defense of the Brain against Infection?","authors":"M. Chuah, A. Vincent, A. West","doi":"10.1159/000094557","DOIUrl":"https://doi.org/10.1159/000094557","url":null,"abstract":"Olfactory ensheathing cells (OECs), also known as olfactory neuroglia, are widely accepted to play a role in the ontogeny of the primary olfactory pathway. Their expression of numerous growth factors and extracellular matrix molecules is consistent with a role in guiding elongating olfactory axons from the nasal cavity to their termination in the olfactory bulb. In recent years, researchers have attempted to exploit these phenotypic features by utilizing these cells as a therapeutic agent to induce repair of the injured nervous system. However, their strategic placement along olfactory nerves, spanning the region between the external nasal cavity and the olfactory bulb (part of the central nervous system), and their expression profile of immunomodulatory proteins support a possible involvement in the protection of the brain against infection. This commentary will briefly outline the relationship between OECs and developing olfactory nerves, and recent experimental evidence that suggests a remarkable functional plasticity of OECs including a possible active role in the immune system.","PeriodicalId":89607,"journal":{"name":"Neuroembryology and aging","volume":"3 1","pages":"152 - 156"},"PeriodicalIF":0.0,"publicationDate":"2004-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000094557","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64345218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Beneficial Effects of Dietary Vitamins, Lipoic Acid and Carnitine on the Aging Brain 膳食维生素、硫辛酸和肉碱对衰老大脑的有益作用
Neuroembryology and aging Pub Date : 2004-07-01 DOI: 10.1159/000094556
T. Ng, X. Ye
{"title":"Beneficial Effects of Dietary Vitamins, Lipoic Acid and Carnitine on the Aging Brain","authors":"T. Ng, X. Ye","doi":"10.1159/000094556","DOIUrl":"https://doi.org/10.1159/000094556","url":null,"abstract":"A number of vitamins including vitamin A/carotenoids, vitamins C and E and lipoic acid, which have antioxidant activity, are capable of improving cognitive performance in senescent animals and elderly subjects. The B vitamins, folic acid and carnitine also exert beneficial actions on the aging brain.","PeriodicalId":89607,"journal":{"name":"Neuroembryology and aging","volume":"3 1","pages":"128 - 135"},"PeriodicalIF":0.0,"publicationDate":"2004-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000094556","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64345210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Peripheral Vestibular Responses to Sound 周围前庭对声音的反应
Neuroembryology and aging Pub Date : 2004-07-01 DOI: 10.1159/000096798
I. Curthoys
{"title":"Peripheral Vestibular Responses to Sound","authors":"I. Curthoys","doi":"10.1159/000096798","DOIUrl":"https://doi.org/10.1159/000096798","url":null,"abstract":"As well as activating the cochlea, sound also activates some vestibular receptors and afferents. That is true for both air- and bone-conducted sound and this review briefly summarizes the neural evidence for vestibular activation by sound in mammals and considers the implications of this result. These neural results have been rapidly translated into clinical use and underpin a new clinical test of human vestibular function using sound as the test stimulus.","PeriodicalId":89607,"journal":{"name":"Neuroembryology and aging","volume":"3 1","pages":"207 - 214"},"PeriodicalIF":0.0,"publicationDate":"2004-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000096798","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64366253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
What Peripheral Vestibular Manipulations Reveal about the Function and Plasticity in the Primate Oculomotor System 外周前庭操作揭示灵长类动眼神经系统的功能和可塑性
Neuroembryology and aging Pub Date : 2004-07-01 DOI: 10.1159/000096795
S. Newlands, D. Angelaki
{"title":"What Peripheral Vestibular Manipulations Reveal about the Function and Plasticity in the Primate Oculomotor System","authors":"S. Newlands, D. Angelaki","doi":"10.1159/000096795","DOIUrl":"https://doi.org/10.1159/000096795","url":null,"abstract":"Central to our understanding of the function and dysfunction of the vestibular system are results from experiments where distinct manipulations of the peripheral vestibular apparatus have been used to characterize deficits and recovery of neural and reflexive responses. Using the primate oculomotor system as a focus, we summarize here recent advances where peripheral vestibular manipulations have revealed important properties of vestibular function and adaptability.","PeriodicalId":89607,"journal":{"name":"Neuroembryology and aging","volume":"39 1","pages":"171 - 182"},"PeriodicalIF":0.0,"publicationDate":"2004-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000096795","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64365908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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