Journal of nutrition & food sciences最新文献

{"title":"Artificial Intelligence-Enhanced Assessment of Lipid Profiles in Commercial Infant Foods in the United States.","authors":"Clement G Yedjou, Kevine Makoudjou, Monica Ochapa, Jinwei Liu, Samia Messeha, Paul B Tchounwou","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Normal consumption of lipids is essential for optimal baby growth and neurological development, yet comprehensive analysis of lipid content in commercial baby foods remains limited. This study provides the first systematic, AI-enhanced assessment of lipid profiles across commercially available infant food products.</p><p><strong>Methods: </strong>A cross-sectional analysis of 245 commercial baby food products was conducted using artificial intelligence and machine learning algorithms for data processing and pattern recognition. Among the 245 commercial baby food products in the United States, 25 products have zero lipid content, while 220 products contain lipids ranging from 0.1 to 28.58 g of lipids. Products were categorized by total lipid content per 100g into four groups: Zero (0.0g), Low (≤ 1.0g), Moderate (>1.0-5.0g), and High (>5.0g). Statistical analyses included descriptive statistics and correlation analysis between ingredient profiles and lipid content.</p><p><strong>Results: </strong>Our analysis revealed that zero-lipid foods for infants comprised 10.2% of food products and were exclusively fruit-based, naturally low in fat, and suitable for early feeding, but limited in energy input. Low-lipid foods for infants accounted for the largest dataset and represented 45.3%, consisting of vegetable purées, fruit purées, and diluted fruit formulations, which reflect typical plant-based lipid profiles yet potentially require complementary higher-fat foods to meet caloric needs. The moderate-lipid food products accounted for 33.9% of the dataset. These food products included grain-vegetable mixtures, fortified fruit blends, and enriched beverages, indicating the incorporation of added oils and/or higher-fat natural ingredients to provide balanced energy.High-lipid foods such as fortified cereals, meat-based meals, and snack-type products made up 10% of the dataset. These items provide significant energy, which is especially important for infants between 6 months and 2 years old, as they have increased caloric needs relative to their size.</p><p><strong>Conclusion: </strong>Using AI and machine learning, this analysis revealed that baby foods on the market show clear variations in fat content linked to their main ingredients. Since many foods are high in fat, caregivers may need to make intentional choices to ensure infants receive adequate energy. These findings offer valuable reference points for parents, pediatric nutrition advice, and future regulatory decisions.</p>","PeriodicalId":89590,"journal":{"name":"Journal of nutrition & food sciences","volume":"16 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13007982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147517539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Garlic Extract Triggers Cytotoxicity, DNA Damage, and Cell Cycle Arrest in Human Leukemic Cells <i>via</i> Oxidative Stress.","authors":"Sylvianne Njiki, Keara Johnson, Jennifer N Sims, Ariane M Chitoh, Clement G Yedjou, Felicite K Noubissi, Barbara Graham, Paul B Tchounwou","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Garlic (<i>Allium sativum</i>) is one of the oldest medicinal plants that has received great attention throughout ancient and modern history. It has been used for the prevention and treatment of a wide variety of ailments, including cancer, cardiovascular disease, and hepatic and microbial infections. Although garlic shows potential in the prevention and treatment of cancer and other diseases, little is known about its therapeutic mechanisms of action. Here, we hypothesized that Garlic Extract (GE) induces cytotoxicity, DNA damage, and cell cycle arrest in Human Leukemia (HL-60) cells through oxidative stress. To test our hypothesis, HL-60 cells were treated with different concentrations (2 mg/mL, 4 mg/mL, and 6 mg/mL) of GE for 24 hours. Cell viability and cell morphology were analyzed by MTT, trypan blue, and Acridine Orange and Propidium Iodide (AO/PI) assays, respectively. The extent of oxidative stress was measured by the lipid peroxidation and glutathione peroxidase assays. The degree of DNA damage was evaluated by single-cell gel electrophoresis. Cell cycle arrest was assessed by the Cellometer Vision. Data obtained from the MTT assay, trypan blue dye, and AO/PI dye assessment indicated that GE significantly reduced the number of live cells in a concentration-dependent manner, showing a gradual increase in the loss of viability in GE-treated cells. MTT assay results also revealed that GE inhibits the viability of HL-60 cells, resulting in an IC₅₀ of 4.72 mg/mL. Tests for oxidative stress indicated significant increases (p<0.05) in the production of Malondialdehyde (MDA) and activity of glutathione peroxidase in GE-treated cells compared to the control group. Data obtained from the comet assay indicated that GE causes DNA damage in HL-60 cells in a concentration-dependent manner. GE treatment modulated cell cycle progression in HL-60 cells, leading to an arrest at the G2/M phase. In summary, our current investigation underscores that GE effectively curbs cell proliferation, induces DNA damage, and enforces cell cycle arrest of HL-60 cells, with these primary effects associated with oxidative stress. These findings contribute to a deeper understanding of the potential therapeutic role of GE in combating acute promyelocytic leukemia and other health challenges.</p>","PeriodicalId":89590,"journal":{"name":"Journal of nutrition & food sciences","volume":"15 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12288681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 Prevalence in Nations with Normal Body Mass Index (BMI): Implications of Artificial Intelligence (AI) in Healthcare.","authors":"Clement G Yedjou, Richard Long, Victor Eno, Jinwei Liu, Shannon Bright Smith, Pierre Ngnepieba, Kwasi Densu, Monique MsCallister, Lekan Latinwo, Paul B Tchounwou","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Coronavirus disease 2019 (COVID-19) has had a profound impact globally, causing the death of millions of people and deeply affecting socio-psychological, human health, and economic systems, with some nations bearing a disproportionate burden. Despite obesity having been established as one of the major risk factors of COVID-19 severity and other degenerative diseases, the effects that dietary pattern intake plays in COVID-19 outcomes remain poorly understood. The goal of this study is to look into the connection between eating habits, the number of non-obese and obese people, and COVID-19 outcomes in countries with populations exhibiting normal Body Mass Index (BMI), which is an indicator of obesity.</p><p><strong>Methods: </strong>The analysis includes data from 170 countries. From the 170 countries, we focused on 53 nations where the average, BMI falls within the normal range (18.5 to 24.9). A subset of 20 nations was selected for a more detailed examination, comprising 10 nations with the lowest BMI values within the normal range (18.5-19.8) and 10 nations with the highest BMI values within the normal range (23.5-24.9). We used Artificial Intelligence (AI) and Machine Learning (ML) applications to evaluate key metrics, including dietary patterns (sugar and vegetable intake), obesity prevalence, incidence rate, mortality rate, and Case Fatality Rate (CFR).</p><p><strong>Results: </strong>The results demonstrate a significant correlation between higher obesity prevalence and increased COVID-19 severity, evidenced by elevated incidence, mortality, and CFRs in countries like North Macedonia and Italy. In contrast, nations such as Iceland and New Zealand with well-established healthcare systems revealed low mortality rate and case fatality rate despite variations in dietary habits. The study also revealed that vegetable consumption appears to provide a slight to significant protective effects, suggesting that dietary patters alone do not consistently predict COVID-19 Outcomes.</p><p><strong>Conclusion: </strong>Data generated from this study showed the crucial role of healthcare infrastructure along with the testing capacity and data reporting in influencing the success of pandemic responses. It also highlights the need of integrating public health strategies, which focus on obesity management and improvement of healthcare preparedness. In addition, AI-driven predictive modeling offers valuable insights that may guide pandemic response efforts in the future, thereby enhancing global health crisis management and mitigating the impact of future health emergencies.</p>","PeriodicalId":89590,"journal":{"name":"Journal of nutrition & food sciences","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12129441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemo-Preventive Effect of Vegetables and Fruits Consumption on the COVID-19 Pandemic.","authors":"Clement G Yedjou, Richard A Alo, Jinwei Liu, Juliet Enow, Pierre Ngnepiepa, Richard Long, Lekan Latinwo, Paul B Tchounwou","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Coronavirus disease 2019 (COVID-19) is a new disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is a global pandemic that has claimed the death of 1,536,957 human beings worldwide including 287,842 deaths in the United States as of December 3, 2020. It has become a major threat to the medical community and the entire healthcare system in every part of the world. Recently, the Food and Drug Administration (FDA) has approved the emergency use of Pfizer and Moderna COVID-19 vaccine on December 12, 2020. However, there are concern about the new COVID-19 vaccine safety, efficacy, and immunity after the vaccination. In addition, both coronavirus and COVID-19 vaccine are new at this point and there is no scientific evidence to know whether people who are vaccinated can still carry the COVID 19 pathogens and pass them along to others. Therefore, many people all over the world have an increased interest in consuming more VF for the purpose of maintaining their health and boosting their immune system. Identifying novel antiviral agents for COVID-19 is of critical importance, and VF is an excellent source for drug discovery and therapeutic development. The objective of this study is to test the hypothesis that a high intake of vegetables and/or fruits prevents COVID-19 incidence and reduces the mortality rate. To achieve this objective, we collected the diet data of COVID-19 from Kaggle (https://www.kaggle.com/mariaren/covid19-healthy-diet-dataset), and used a machine-learning algorithm to examine the effects of different food types on COVID-19 incidences and deaths. Specifically, we used the feature selection method to identify the factors (e.g., diet-related factors) that contribute to COVID-19 morbidity and mortality. Data generated from the study demonstrated that VF intake can help to combat the SARS-CoV-2. Taken together, VF may be potential chemopreventive agents for COVID-19 due to their antiviral properties and their ability to boost the human body immune system.</p>","PeriodicalId":89590,"journal":{"name":"Journal of nutrition & food sciences","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38817850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aspects of mental health and its relation to nutritional intake in two community based hospital: Its importance in behavior","authors":"pJose Rodriguez Gomezp","doi":"10.4172/2155-9600-C2-093","DOIUrl":"https://doi.org/10.4172/2155-9600-C2-093","url":null,"abstract":"","PeriodicalId":89590,"journal":{"name":"Journal of nutrition & food sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47362180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastrointestinal tract - Immunology","authors":"pHadeel Saud Alshubailip","doi":"10.4172/2155-9600-C1-089","DOIUrl":"https://doi.org/10.4172/2155-9600-C1-089","url":null,"abstract":"","PeriodicalId":89590,"journal":{"name":"Journal of nutrition & food sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48117231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bile Acid Metabolism is an Intermediary Factor between Non-Alcoholic Steatohepatitis and Ischemic Heart Disease in SHRSP5/Dmcr Rats","authors":"Shota Kumazaki, Mayumi Nakamura, S. Sasaki, Rina Tagashira, Nozomi Maruyama, Ikumi Sato, Shusei Yamamoto, S. Ran, S. Usui, R. Shinohata, T. Ohtsuki, S. Hirohata, K. Kitamori, M. Mori, Y. Yamori, Shogo Watanabe","doi":"10.35248/2155-9600.19.9.763","DOIUrl":"https://doi.org/10.35248/2155-9600.19.9.763","url":null,"abstract":"The non-alcoholic steatohepatitis (NASH) increases the cardiovascular risk regardless of risk factors in metabolic syndrome. The stroke-prone (SP) spontaneously hypertensive rats (SHRSP5/Dmcr), fed a high-fat and -cholesterol (HFC) diet and administered Nω-Nitro-L-arginine methyl ester hydrochloride (L-NAME) presented NASH and cardiovascular disease. However, the intermediary factors between NASH and cardiovascular risk are still unknown. We investigated whether bile acids (BAs) play an intermediary role between NASH and cardiovascular disease in SHRSP5/Dmcr rats. SHRSP5/Dmcr rats divided into 2 groups were fed an SP (non-NASH group, n=7) or HFC diet (NASH group, n=10) for 8 weeks. L-NAME was administered intraperitoneally in the final 2 weeks. In the NASH group, total BA levels were increased in both serum and liver; they aggravated the endothelial dysfunction in aorta, which is the first step to atherosclerosis, and activated the gene expression levels of cell adhesion molecules (vascular cell adhesion molecule-1, intercellular adhesion molecule-1) in coronary artery. In particular, the nuclear factor-kappa B (NFkB) was increased in the NASH group in the coronary endothelial cells activated by high BA levels. We demonstrated that liver BAs aggravated steatosis and fibrosis and serum BA accelerated arteriosclerosis and ischemic heart disease via the classical pathway of NFkB in the endothelial cells. BA metabolism disorder may be an intermediary factor between NASH and cardiovascular risk in SHRSP5/Dmcr rats.","PeriodicalId":89590,"journal":{"name":"Journal of nutrition & food sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69968265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-Cancer Properties Of Cinnamon Oil And Its Active Component, Trans-Cinnamaldehyde","authors":"Marc A Thompson, E. Schmelz, L. Bickford","doi":"10.4172/2155-9600.1000750","DOIUrl":"https://doi.org/10.4172/2155-9600.1000750","url":null,"abstract":"Bioactive dietary agents (i.e., nutraceuticals) have shown the ability to slow or eliminate cancer growth with marked immediate effects when applied directly to cancer cells. By isolation and inspection of the effective components in these therapeutic agents, with respect to cancer cell inhibition, a clear mechanism of action can contribute to a better understanding of the benefits of these natural products. Here we have examined the effects of three essential oil formulations of nutraceutical agents: Frankincense, Garlic and Cinnamon, and ultimately investigated trans-cinnamaldehyde (TC), the active ingredient in cinnamon oil and a documented anti-inflammatory and anti-cancer agent, on cell viability and migratory potential in in vitro models of breast cancer representing different tumorigenic and metastatic potential. Results show that TC exhibits a clear dose-response relationship in inhibiting cancer cell survival and migration in a breast cancer aggression-dependent manner. Our results suggest that TC may be a promising candidate for the development of effective strategies to counter breast cancer in vivo by reducing or eliminating its progression.","PeriodicalId":89590,"journal":{"name":"Journal of nutrition & food sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70300542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Larygopharyngeal Reflux (LPR) diet","authors":"A. Hariri","doi":"10.4172/2155-9600-c2-091","DOIUrl":"https://doi.org/10.4172/2155-9600-c2-091","url":null,"abstract":"","PeriodicalId":89590,"journal":{"name":"Journal of nutrition & food sciences","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70300689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iodine Content of Malaysian Foods","authors":"N. M. Khalid, N Faridus, Razak L. Abd, Sukardi Na, A. Rashed, Rusidah Selamat, M. F. M. Noh","doi":"10.35248/2155-9600.19.9.764","DOIUrl":"https://doi.org/10.35248/2155-9600.19.9.764","url":null,"abstract":"Background: Iodine is an essential mineral that is important for human nutrition. Iodine content was determined in 138 Malaysian food samples using inductively coupled plasma-mass spectrometry. Method: The samples include 31 cereal products, 9 starchy root and tuber products, 4 legume products, 11 nut and seed products, 4 vegetables, 5 fruits, 22 sugar and syrup products, 3 meat products, 3 eggs, 7 fishes, 14 milk products, 11 oil and fat products, 1 beverage and 13 other food products. Up to six different brands were sampled from local supermarkets in the Klang Valley, Malaysia. Results: The results showed that the concentration of iodine in the Malaysian food samples varied according to food groups. The iodine values were found to be in range of 3.71-100.64 μg/100 g for cereal products, 8.78-53.50 μg/100 g for starchy root and tuber products, 6.72-30.19 μg/100 g for legume products, 8.16-35.98 μg/100 g for nut and seed products, 1.57-2.44 μg/100 g for vegetables, 1.56-2.20 μg/100 g for fruits, 0.06-23.90 μg/100 g for sugar and syrups products, 5.79-24.36 μg/100 g for meat products, 16.88-158.70 μg/100 g for eggs, 25.21-53.27 μg/100 g for fish, 8.57-61.63 μg/100 g for milk products, 3.58-160.00 μg/100 g for oil and fat products and 2.84-56.72 μg/100 g for other food products. Conclusion: In conclusion, Malaysian foods showed large variation in iodine content with main iodine food source from the marine environment, iodized salt and fortified animal feeds.","PeriodicalId":89590,"journal":{"name":"Journal of nutrition & food sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69967844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}