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Electric-Potential Reconstructions of Single Particles Using L-Gradient Flows. 利用l梯度流重建单粒子电势。
Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics Pub Date : 2010-10-18 DOI: 10.1109/BMEI.2010.5639445
Ming Li, Guoliang Xu, Carlos O S Sorzano, Roberto Melero, Chandrajit Bajaj
{"title":"Electric-Potential Reconstructions of Single Particles Using L-Gradient Flows.","authors":"Ming Li, Guoliang Xu, Carlos O S Sorzano, Roberto Melero, Chandrajit Bajaj","doi":"10.1109/BMEI.2010.5639445","DOIUrl":"10.1109/BMEI.2010.5639445","url":null,"abstract":"<p><p>In this paper, we present a stable, reliable and robust method for reconstructing a three dimensional density function from a set of two dimensional electron microscopy images. By minimizing an energy functional consisting of a fidelity term and a regularization term, a L(2)-gradient flow is derived. The flow is integrated by a finite element method in the spatial direction and an explicit Euler scheme in temporal direction. The experimental results show that the proposed method is efficient and effective.</p>","PeriodicalId":89462,"journal":{"name":"Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics","volume":"1 ","pages":"213-217"},"PeriodicalIF":0.0,"publicationDate":"2010-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091820/pdf/nihms249632.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30181128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality Multi-domain Meshing for Volumetric Data. 体积数据的高质量多域网格划分
Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics Pub Date : 2010-10-16 DOI: 10.1109/BMEI.2010.5639253
Qin Zhang, Bharadwaj Subramanian, Guoliang Xu, Chandrajit L Bajaj
{"title":"Quality Multi-domain Meshing for Volumetric Data.","authors":"Qin Zhang, Bharadwaj Subramanian, Guoliang Xu, Chandrajit L Bajaj","doi":"10.1109/BMEI.2010.5639253","DOIUrl":"10.1109/BMEI.2010.5639253","url":null,"abstract":"<p><p>Multi-domain meshing from volumetric data is of great importance in many fields like medicine, biology and geology. This paper proposes a new approach to produce a high quality mesh with separated multiple domains. A point cloud is generated from a preliminary mesh representing the boundary between different domains from the discrete volumetric representation used as input. A higher-order level-set method is employed to produce a quality sub-mesh from this point cloud and geometric flow is used as smoothing mechanism. A new approach to detect and curate intersections within an assembly of these 2-manifold sub-meshes by utilizing the intermediate volumetric representation is developed. The separation between sub-meshes can be controlled by the user using a gap threshold parameter. The resulting high quality multi-domain mesh is free from self- and inter-domain intersections and can be further utilized in finite element and boundary element computations. The proposed pipeline has been efficiently implemented and sample meshes have been provided for visualization.</p>","PeriodicalId":89462,"journal":{"name":"Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics","volume":"2010 ","pages":"472-476"},"PeriodicalIF":0.0,"publicationDate":"2010-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085488/pdf/nihms249617.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29859186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Cyclic Stretching on Proliferation and Viscoelasticity of Lung Adenocarcinoma Cells 循环拉伸对肺腺癌细胞增殖和粘弹性的影响
Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5303263
H. Qu
{"title":"Effect of Cyclic Stretching on Proliferation and Viscoelasticity of Lung Adenocarcinoma Cells","authors":"H. Qu","doi":"10.1109/BMEI.2009.5303263","DOIUrl":"https://doi.org/10.1109/BMEI.2009.5303263","url":null,"abstract":"Using FX-4000 strain unit, the proliferation and viscoelasticity of human lung adenocarcinoma A549 cells that underwent different mechanical strain were investigated. Flow Cytometer and A micropipette aspiration technique were adopted to investigate the proliferation and viscoelasticity of A549 cells. A standard linear solid model was adopted to fit the experimental data. Experimental results indicated that cell proliferation index (PI) and viscoelastic coefficients K1, K 2 and µ reduce significantly after A549 cells are subjected to square wave with 15% elongation at frequency 0.5Hz for 4h , the PI and viscoelastic coefficients have no distinct difference between sine wave- treated cells and control A549 cells. The deformability increases and the rigidity decreases for square wave-treated cells. while the PI of A549 cells reduces significantly, the viscoelastic coefficient of A549 cells reduces significantly similarly. All of these suggest that We can restrain A549 cells proliferation by alter cells viscoelasticity.","PeriodicalId":89462,"journal":{"name":"Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics","volume":"1 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2009-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79899020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Protein Adsorption and Biocompatibility of Porous Silk Fiboin Films 多孔丝质纤维蛋白膜的蛋白质吸附和生物相容性
Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305691
ZiLing Sun, L. Bai, Guoping Guan, KuiHua Zhan, HongQin Dai
{"title":"Protein Adsorption and Biocompatibility of Porous Silk Fiboin Films","authors":"ZiLing Sun, L. Bai, Guoping Guan, KuiHua Zhan, HongQin Dai","doi":"10.1109/BMEI.2009.5305691","DOIUrl":"https://doi.org/10.1109/BMEI.2009.5305691","url":null,"abstract":"Silk fibroins are widely used in skin wound healing and tissue engineering scaffolds. This study sought to observe proteins adsorption and biocompatibility. Bradford protein assay revealed that the amount of adsorbed proteins was significantly less than that on PVA. The Sodium Dodecyl Sulfate Polyacrylamidege Electrophoresis (SDS-PAGE) indicated that more proteins adsorbed onto PVA than that PSFFs. Identification of adsorbed proteins by Western blotting revealed that there was lesser amount of fibrinogen on PSFFs than on PVA. Histologic observation after 10 days PSFFs implantation in shin and muscle of rat showed that some capillaries and microvessels grew in PSFFs, PSFFs and peri- tissues were mixed with each other, many fibroblasts, myocytes and lipocytes could be observed in PSFFs due to good biocompatibility. Keywords—protein adsorption; fibrinogen; Porpous Silk Fibroin Films (PSFFs)","PeriodicalId":89462,"journal":{"name":"Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics","volume":"69 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2009-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79127742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-Rigid Surface Matching Technique as a Tool in Scoliosis Deformation Modelling 非刚性曲面匹配技术在脊柱侧凸变形建模中的应用
Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305412
K. Ang
{"title":"Non-Rigid Surface Matching Technique as a Tool in Scoliosis Deformation Modelling","authors":"K. Ang","doi":"10.1109/BMEI.2009.5305412","DOIUrl":"https://doi.org/10.1109/BMEI.2009.5305412","url":null,"abstract":"We present a novel approach for deformation modelling and exploit it on scoliosis monitoring. Despite the extensive use of surface topographies to monitor scoliosis, shape change due to scoliosis deformities has never been satisfactorily resolved. A novel non-rigid surface matching algorithm with nine new parameters has been investigated and developed. This non-rigid matching algorithm has been trialled using models with predictable topographic deformation. There is evidence that surface deformities can be modelled. In addition, to demonstrate the capability of this new non-rigid matching algorithm in scoliosis modelling, we have performed experimental comparison with classical rigid matching algorithm using four different scoliosis data sets. The non-rigid matching algorithm returned r.m.s. values which were improved by at least 10%. The experimental results are very promising, demonstrating that this new non-rigid matching algorithm is able to improve the precision and the accuracy of the matching. Analysis indicates that this new non-rigid matching algorithm has proven to be a very successful tool and is an improvement on the classical approach. Meanwhile the new parameters are able to delineate the possible spatial distribution of surface deformation. 1. Background","PeriodicalId":89462,"journal":{"name":"Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics","volume":"53 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2009-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74846490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Design and Implementation of a Signal Source for EIT System Using DSP Builder 基于DSP Builder的EIT系统信号源设计与实现
Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305850
Y. Wu, H. Sha, C. Ren
{"title":"The Design and Implementation of a Signal Source for EIT System Using DSP Builder","authors":"Y. Wu, H. Sha, C. Ren","doi":"10.1109/BMEI.2009.5305850","DOIUrl":"https://doi.org/10.1109/BMEI.2009.5305850","url":null,"abstract":"A signal source for EIT system is designed and realized in this paper .Firstly, a brief introduction and some theoretical analysis are made about the basic principles of Direct Digital Synthesizer, DDS. Then a DDS module based on DSP Builder is built, according to the performance requirement of the hardware circuit of EIT system. Simulations and verification of the built DDS module is carried out and results shows that the performance of the DDS signal source is in the accord with the actual requirement of EIT system. The DDS error is also analyzed to assure the correctness of the design. Finally, the method of realizing the signal source is given to accomplish DDS on the EP2C35F672C6, one of the cyclone series FPGA chips supplied by Altera Corporation.)","PeriodicalId":89462,"journal":{"name":"Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics","volume":"45 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2009-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81347978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computational Fluid Dynamics Modeling of Intracranial Aneurysms 颅内动脉瘤的计算流体动力学建模
Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics Pub Date : 2008-05-27 DOI: 10.1109/BMEI.2008.91
Jialiang Chen, Shengzhang Wang, Wei Yao, Guanghong Ding
{"title":"Computational Fluid Dynamics Modeling of Intracranial Aneurysms","authors":"Jialiang Chen, Shengzhang Wang, Wei Yao, Guanghong Ding","doi":"10.1109/BMEI.2008.91","DOIUrl":"https://doi.org/10.1109/BMEI.2008.91","url":null,"abstract":"Hemodynamic factors like the wall shear stress (wss) play an important role in the pathogenesis and treatment of intracranial aneurysms. In this article, we applied computational fluid dynamic analysis on one patient-specific model of cerebral aneurysm and connected vessels constructed from 3D rotational angiography in order to understand the properties of blood flow around aneurysms and wall shear stress. Our whole simulation process is based on a series of CFD commercial software packages that is easy for clinicians to implement such method and use it in their daily practice. From the patient model analyzed in this investigation, we find that the comparatively maximum WSS occurs near the root of the aneurysm, which leads to damage in the aneurysmal wall, and the maximum displacement is at the peak of the aneurysm.","PeriodicalId":89462,"journal":{"name":"Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics","volume":"12 1","pages":"566-569"},"PeriodicalIF":0.0,"publicationDate":"2008-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76444858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Single Droplet Evaporation Model in Laser Treatment of PWS in Conjunction with Cryogen Spray Cooling 冷冻剂喷雾冷却激光治疗PWS的单液滴蒸发模型
Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics Pub Date : 2008-05-27 DOI: 10.1109/BMEI.2008.279
Zhou Zhi-fu, Xin Hui, C. Bin, Wan Guo-xiang
{"title":"Single Droplet Evaporation Model in Laser Treatment of PWS in Conjunction with Cryogen Spray Cooling","authors":"Zhou Zhi-fu, Xin Hui, C. Bin, Wan Guo-xiang","doi":"10.1109/BMEI.2008.279","DOIUrl":"https://doi.org/10.1109/BMEI.2008.279","url":null,"abstract":"Cryogen spray is an effective cooling technique used for laser treatment of port wine stain. The cooling process involves complex droplet evaporation and strong convective heat and mass transfer, therefore a deep understanding of spray characteristics is essential in order to optimize the nozzle design and improve the cooling efficiency of the spray. This paper presents a theoretical model to describe the equilibrium evaporation process of a single cryogen droplet in cryogen spray. The model considers mass transfer through mass transfer number method, the momentum transfer by selecting the suitable empirical correlation of drag coefficient, and heat transfer by taking into consideration of droplet evaporation and convective effect with ambient air. The influence of variable physical properties of R134a is also considered. Based on the validation by simulating the cooling stage of a hanging water droplet, this model is used to predict the temperature variation of cryogen droplets in cryogen spray, which is in reasonable agreement with the experimental measurements. A parametric study of the influences of initial diameter and velocity on the droplet evaporation is then carried out. The results can be used to guide the cryogen spray cooling of laser therapy.","PeriodicalId":89462,"journal":{"name":"Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics","volume":"34 1","pages":"551-556"},"PeriodicalIF":0.0,"publicationDate":"2008-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86916511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Tissue Cell Boundaries Detection based on Curvelet-based Snake Model in Electrorotation Bio-chip Control System 电旋转生物芯片控制系统中基于曲线蛇模型的组织细胞边界检测
Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics Pub Date : 2008-05-27 DOI: 10.1109/BMEI.2008.139
Yang Qihua, Wang Qiang
{"title":"Tissue Cell Boundaries Detection based on Curvelet-based Snake Model in Electrorotation Bio-chip Control System","authors":"Yang Qihua, Wang Qiang","doi":"10.1109/BMEI.2008.139","DOIUrl":"https://doi.org/10.1109/BMEI.2008.139","url":null,"abstract":"During cell motility tracking process, to suppress background interference and separate the clustering cells contour, a novel cell boundary feature extraction algorithm based on snake model and curvelet transform(CT) is proposed. The CT has higher time-frequency resolution, high degree of directionality and anisotropy. Microscope cell image is denoised by discrete CT to improve SNR. Then curvelet-based Snake model in multiscale space is applied to identify cell contour, which obtains cell boundaries under the effect of both the original image force and the modified nonlinear distance image force. It is effective for electrorotation cell contour extraction corrupted by noise, with weak edges. Experimental results show good performances of the proposed method to extract the shape of edges and quantification of cell motility.","PeriodicalId":89462,"journal":{"name":"Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics","volume":"25 1","pages":"728-732"},"PeriodicalIF":0.0,"publicationDate":"2008-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74302199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Primary Study on Dielectric Property Detection for Cerebral Haematoma 脑血肿介质特性检测的初步研究
Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics Pub Date : 2008-05-27 DOI: 10.1109/BMEI.2008.127
Wang Chao, Zhang Ming, Wang Xiang-yu, Wu Dong-yue, Wang Huaxiang
{"title":"Primary Study on Dielectric Property Detection for Cerebral Haematoma","authors":"Wang Chao, Zhang Ming, Wang Xiang-yu, Wu Dong-yue, Wang Huaxiang","doi":"10.1109/BMEI.2008.127","DOIUrl":"https://doi.org/10.1109/BMEI.2008.127","url":null,"abstract":"It's found that the distinction of permittivity of different tissues is more obvious, according to analyzing the changing regularity of the conductivity and permittivity of the head tissue at different frequency. A capacitance measuring method based on dielectric property is presented, which aims at detecting the haematoma as well as its development expediently. According to the head structure, a multi-layer head model is built up with ANSYS analysis software. The different states of haematoma such as the position, size and the extent of approaching the measuring electrode are analyzed in two-dimension model. The feasibility of the measurement is proved.","PeriodicalId":89462,"journal":{"name":"Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics","volume":"22 1","pages":"482-486"},"PeriodicalIF":0.0,"publicationDate":"2008-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78647129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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