ISRN urology最新文献_第6页

Ten-year experience with open prostatectomy in maiduguri. 迈杜古里十年开放性前列腺切除术的经验。

ISRN urology Pub Date : 2012-01-01 Epub Date: 2012-11-27 DOI: 10.5402/2012/406872

Ibrahim Ahmed Gadam, Ali Nuhu, Suleiman Aliyu

{"title":"Ten-year experience with open prostatectomy in maiduguri.","authors":"Ibrahim Ahmed Gadam, Ali Nuhu, Suleiman Aliyu","doi":"10.5402/2012/406872","DOIUrl":"https://doi.org/10.5402/2012/406872","url":null,"abstract":"Background. Benign prostatic hyperplasia is the most common cause of lower urinary tract obstruction in the elderly male. Aim. To evaluate the effectiveness, safety, and outcome of open prostatectomy in a Nigerian teaching hospital. Material and Methods. Two hundred and fifty-three men with lower urinary tract obstruction clinically due to benign prostatic hyperplasia (BPH) underwent open prostatectomy over a ten-year period (January 2001-December 2010). Data on patients including age, clinical, laboratory, and histology were reviewed and analyzed to determine treatment outcome. Results. A total of 253 patients were studied. Their mean age was 69.11 ± 10.9 years (range 50-98). The most common symptoms at presentation included frequency 229 (90.5%) and poor stream 225 (88.9%). The most common complications at presentation were stones in 41 (16.2%) and bleeding in 37 (14.6%). The most common comorbid conditions were hypertension and diabetes found in 72 (28.5%) and 23 (9.1%), respectively. Transvesical prostatectomy was done for most of the patients, 126 (49.8%). Clot retention and wound infection were the commonest postoperative complications accounting for 19 (7.5%) each. Transient incontinence occurred in 17 (6.7%) patients. There was 1 (0.4%) mortality. Conclusion. Open prostatectomy still has a prime place in the operative treatment of BPH with acceptable postoperative morbidity and very low mortality in the developing world with no facilities for TURP.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2012 ","pages":"406872"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/406872","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31113541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Pharmacotherapy in pediatric neurogenic bladder intravesical botulinum toxin type a. 小儿神经性膀胱膀胱内a型肉毒杆菌毒素的药物治疗。

ISRN urology Pub Date : 2012-01-01 Epub Date: 2012-06-07 DOI: 10.5402/2012/763159

Cristian Sager, Carol Burek, Victor Durán, Juan Pablo Corbetta, Santiago Weller, Bortagaray Juan, Juan Carlos López

引用次数: 11

A novel membrane protein-specific serine/threonine kinase: tissue distribution and role in sperm maturation. 一种新型膜蛋白特异性丝氨酸/苏氨酸激酶：组织分布和在精子成熟中的作用。

ISRN urology Pub Date : 2012-01-01 Epub Date: 2012-03-01 DOI: 10.5402/2012/789105

Debjani Nath, Arpita Bhoumik, Sujoy Das, Debdas Bhattacharyya, Sandhya R Dungdung, Gopal C Majumder

引用次数: 0

Increased fertilization rates after in vitro culture of frozen-thawed testicular immotile sperm in nonobstructive azoospermic patients. 非阻塞性无精子症患者冷冻解冻睾丸不动精子体外培养后受精率的提高。

ISRN urology Pub Date : 2012-01-01 Epub Date: 2012-03-05 DOI: 10.5402/2012/108576

R Nuñez-Calonge, S Cortes, M Gago, P López, P Caballero-Peregrin

{"title":"Increased fertilization rates after in vitro culture of frozen-thawed testicular immotile sperm in nonobstructive azoospermic patients.","authors":"R Nuñez-Calonge, S Cortes, M Gago, P López, P Caballero-Peregrin","doi":"10.5402/2012/108576","DOIUrl":"https://doi.org/10.5402/2012/108576","url":null,"abstract":"Objective. To optimise the use of freeze/thaw testicular immotile spermatozoa from nonobstructive azoospermia patients and to analyse the outcome of intracytoplasmic sperm injection (ICSI) of such spermatozoa. Methods. Testicular specimens were retrieved and cryopreserved from forty patients with nonobstructive azoospermia and underwent one cycle with thawed spermatozoa (Group I) that led to pregnancy in sixteen cases. Twenty-four patients of group I underwent treatment with the same batch of thawed spermatozoa (Group II). For the first ICSI attempt, injection was performed when motile spermatozoa were found. In group II, injection was performed when maximum motility was reached. We compared mean of fertilization rate, embryo quality, clinical pregnancy rate and embryo implantation rate. Results. The mean percentage of motility was significantly higher in the group II than in the group I (18, 6 versus 8, 2). Group I showed a significant decrease in fertilization rates when compared with cryopreserved testicular spermatozoa in group II (54% versus 72%, P < 0.05). No difference was noted between the cleavage rate, embryo quality, clinical pregnancy rates and implantation rates among group II and I. Conclusion. Fecundation rate can be significantly improved after in-vitro culture and sperm selection of frozen-thawed immotile testicular spermatozoa in patients with nonobstructive azoospermia.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2012 ","pages":"108576"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/108576","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30602002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Tissue banking: relationship with blood donor and organ donor card status. 组织库:与献血者和器官捐献卡状态的关系。

ISRN urology Pub Date : 2012-01-01 Epub Date: 2012-03-05 DOI: 10.5402/2012/475729

Kenneth D McKenzie, Patricia E Fitzpatrick, John D Sheehan

{"title":"Tissue banking: relationship with blood donor and organ donor card status.","authors":"Kenneth D McKenzie, Patricia E Fitzpatrick, John D Sheehan","doi":"10.5402/2012/475729","DOIUrl":"https://doi.org/10.5402/2012/475729","url":null,"abstract":"Understanding the relationships among altruistic health acts may serve to aid therapeutic research advances. In this paper, we report on the links between two such behaviours-donating blood and carrying an organ donor card-and willingness to donate urological tissue to a tissue bank. Reasons for the differential willingness to do so are examined in this paper. A systematic sample of 259 new and returning attendees at a tertiary urology referral clinic in Ireland completed a self-report questionnaire in an outpatient setting. In addition to demographic details, details of known diagnosis of malignancy and family history of cancer; attitudes to tissue donation for research purposes were gauged using a 5-point Likert scale. Both blood donors and organ donor card carriers were more likely to be willing to donate tissue for research purposes. Blood donors were more likely want to know their overall results in comparison to nonblood donors and want their samples to be used for nonprofit research. Our hypothesis that being a blood donor would be a better predictor to donate urological tissue than being an organ donor card carrier borne out by the trends reported above.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2012 ","pages":"475729"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/475729","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30602007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Low-dose chemotherapy with insulin (insulin potentiation therapy) in combination with hormone therapy for treatment of castration-resistant prostate cancer. 低剂量胰岛素化疗(胰岛素增强疗法)联合激素治疗去势抵抗性前列腺癌。

ISRN urology Pub Date : 2012-01-01 Epub Date: 2012-05-08 DOI: 10.5402/2012/140182

Christo Damyanov, Desislava Gerasimova, Ivan Maslev, Veselin Gavrilov

{"title":"Low-dose chemotherapy with insulin (insulin potentiation therapy) in combination with hormone therapy for treatment of castration-resistant prostate cancer.","authors":"Christo Damyanov, Desislava Gerasimova, Ivan Maslev, Veselin Gavrilov","doi":"10.5402/2012/140182","DOIUrl":"https://doi.org/10.5402/2012/140182","url":null,"abstract":"Purpose. To evaluate the results and quality of life of patients with resistant of castration-resistant tumors previously treated with Insulin-potentiation therapy (IPT) combined with hormone therapy. Materials and methods. Sixteen patients with metastasis prostate tumors after bilateral castration, androgenic blockade, and progression of the disease were observed during the study. The patients were divided into two groups: group A consisting of 8 patients treated with low-dose chemotherapy Epirubicin, Vinblastine, and Cyclophosphamide combined with LHRH agonist and group B consisting of another 8 patients treated with low-dose chemotherapy Docetaxel combined with LHRH agonist. Results. The overall (groups A and B) results concerning PSA after the sixth IPT show partial effect in 8 out of 16 (50%) patients, stabilization in 4 out of 16 (25%), and progression in 4 out of 16 (25%). The median survival for all treated patients is 11,7 months (range 3-30 months). During the treatment no significant side effects were observed, and no lethal cases occurred. Conclusion. In spite of the small number of the treated patients with castration-resistant prostate tumors, the preliminary results are promising and this gives us hope and expectations for future serious multicenter research over the possibilities for routine implementation of IPTLD.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2012 ","pages":"140182"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/140182","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30656225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Role of ultrasonography in the preoperative assessment of impalpable testes: a single center experience. 超声在无法触及睾丸术前评估中的作用：单中心经验。

ISRN urology Pub Date : 2012-01-01 Epub Date: 2012-03-22 DOI: 10.5402/2012/560216

Tariq O Abbas, Noora Al-Shahwani, Ahmed Hayati, Abdul Hady Samaha, Ibrahim E Bassiouny, Mansour Ali

引用次数: 0

Matrix Metalloproteinases and Bladder Cancer: What is New? 基质金属蛋白酶与膀胱癌:有什么新进展?

ISRN urology Pub Date : 2012-01-01 Epub Date: 2012-07-17 DOI: 10.5402/2012/581539

O Rodriguez Faba, J Palou-Redorta, J M Fernández-Gómez, F Algaba, N Eiró, H Villavicencio, F J Vizoso

{"title":"Matrix Metalloproteinases and Bladder Cancer: What is New?","authors":"O Rodriguez Faba, J Palou-Redorta, J M Fernández-Gómez, F Algaba, N Eiró, H Villavicencio, F J Vizoso","doi":"10.5402/2012/581539","DOIUrl":"https://doi.org/10.5402/2012/581539","url":null,"abstract":"Urothelial bladder cancer represents a heterogeneous disease with divergent pathways of tumorigenesis. Tumor invasion and progression are a multifactorial process promoted by microenvironmental changes that include overexpression of matrix metalloproteinases (MMPs). Recent data clearly challenge the classic dogma that MMPs promote metastasis only by modulating the remodeling of extracellular matrix. Indeed, MMPs have also been attributed as an impact on tumor cell behavior in vivo as a consequence of their ability to cleave growth factors, cell surface receptors, cell adhesion molecules, and chemokines/cytokines. Levels of the different MMPs can be measured in several sample types, including tissue, blood (serum and plasma), and urine, and using different methodologies, such as immunohistochemistry, real-time PCR, western and northern blot analyses, enzyme-linked immunosorbent assay, and zymography. Several MMPs have been identified as having potential diagnostic or prognostic utility, whether alone or in combination with cytology. Although MMP inhibitors have shown limited efficacy, advances in the understanding of the complex physiologic and pathologic roles of MMPs might permit the development of new MMP-specific and tumor-specific therapies. In this paper we update the understanding of MMPs based on a systematic PubMed search encompassing papers published up to December 2011.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2012 ","pages":"581539"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5402/2012/581539","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30803457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 39

Phimosis in children. 儿童包茎。

ISRN urology Pub Date : 2012-01-01 Epub Date: 2012-03-05 DOI: 10.5402/2012/707329

Sukhbir Kaur Shahid

引用次数: 45

Renal Cell Carcinoma Update: News from the AUA, EAU, and ASCO Annual Meetings 2011. 肾细胞癌最新进展：2011 年 AUA、EAU 和 ASCO 年会新闻。

ISRN urology Pub Date : 2012-01-01 Epub Date: 2012-06-10 DOI: 10.5402/2012/748235

Andres Jan Schrader, Sandra Steffens

引用次数: 0