ISRN surgery最新文献_第2页

Surgical management of malignant pleural mesothelioma: impact of surgery on survival and quality of life-relation to chemotherapy, radiotherapy, and alternative therapies. 恶性胸膜间皮瘤的手术治疗:手术对生存和生活质量的影响——与化疗、放疗和替代疗法的关系。

ISRN surgery Pub Date : 2014-02-03 eCollection Date: 2014-01-01 DOI: 10.1155/2014/817203

Sotiris Papaspyros, Sayonara Papaspyros

{"title":"Surgical management of malignant pleural mesothelioma: impact of surgery on survival and quality of life-relation to chemotherapy, radiotherapy, and alternative therapies.","authors":"Sotiris Papaspyros, Sayonara Papaspyros","doi":"10.1155/2014/817203","DOIUrl":"https://doi.org/10.1155/2014/817203","url":null,"abstract":"Introduction. Malignant pleural mesothelioma (MPM) is an aggressive cancer arising from pleural mesothelium. Surgery aims to either cure the disease or control the symptoms. Two surgical procedures exist: extrapleural pneumonectomy (EPP) and pleurectomy/decortication (P/D). In this systematic review we assess current evidence on safety and efficacy of surgery. Methods. Five electronic databases were reviewed from January 1990 to January 2013. Studies were selected according to a predefined protocol. Primary endpoint was overall survival. Secondary endpoints included quality of life, disease-free survival, disease recurrence, morbidity, and length of hospital stay. Results. Sixteen studies were included. Median survival ranged from 8.1 to 32 months for P/D and from 6.9 to 46.9 months for EPP. Perioperative mortality was 0%-9.8% and 3.2%-12.5%, respectively. Perioperative morbidity was 5.9%-55% for P/D and 10%-82.6% for EPP. Average length of stay was 7 days for P/D and 9 days for EPP. Conclusion. Current evidence cannot definitively answer which procedure (EPP or P/D) is more beneficial in terms of survival and operative risks. This systematic review suggests that surgery in the context of trimodality therapy offers acceptable perioperative outcomes and long-term survival. Centres specialising in MPM management have better results. ","PeriodicalId":89400,"journal":{"name":"ISRN surgery","volume":" ","pages":"817203"},"PeriodicalIF":0.0,"publicationDate":"2014-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/817203","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40305891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 25

Coloplasty Neorectum versus Straight Anastomosis in Low Rectal Cancers. 低位直肠癌结直肠成形术与直口吻合的比较。

ISRN surgery Pub Date : 2014-01-30 eCollection Date: 2014-01-01 DOI: 10.1155/2014/382371

Fazl Q Parray, Javaid A Magray, Manzoor Ahmad Dar, Nisar A Chowdri, Rauf A Wani, Natasha Thakur

{"title":"Coloplasty Neorectum versus Straight Anastomosis in Low Rectal Cancers.","authors":"Fazl Q Parray, Javaid A Magray, Manzoor Ahmad Dar, Nisar A Chowdri, Rauf A Wani, Natasha Thakur","doi":"10.1155/2014/382371","DOIUrl":"https://doi.org/10.1155/2014/382371","url":null,"abstract":"Introduction. Patients with the diagnosis of carcinoma rectum after random allocation were assigned to 2 groups. One group was subjected to total mesorectal excision with coloplasty neorectum reconstruction and another group to total mesorectal excision with straight anastomosis. This randomization was done by odds and even method by the sister in charge of the ward to avoid bias in randomization. The study included 42 patients with diagnosis of carcinoma rectum from 4 to 12 centimeters from anal verge. Composite incontinence score, bladder function, and sexual function were considered as the main outcome measures. Results. All patients of transverse coloplasty group had mild or moderate composite incontinence score while 7 (36.8%) patients of straight anastomosis group had a severe score at 7th POD (P < 0.05). At 6 months, 100% patients in transverse coloplasty group had a nil score which was not achieved by any of the patients in the other group. An intragroup comparison showed an improvement in score with time in both groups more marked in transverse coloplasty group. Conclusion. Transverse coloplasty group showed a better QOL so far as anal incontinence is considered. However, no statistically significant difference was achieved when comparing bladder and sexual dysfunction between the two groups. ","PeriodicalId":89400,"journal":{"name":"ISRN surgery","volume":" ","pages":"382371"},"PeriodicalIF":0.0,"publicationDate":"2014-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/382371","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40305890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Sentinel lymph node biopsy in uterine cervical cancer patients: ready for clinical use? A review of the literature. 宫颈癌前哨淋巴结活检:准备好临床应用了吗?文献综述。

ISRN surgery Pub Date : 2014-01-16 eCollection Date: 2014-01-01 DOI: 10.1155/2014/841618

Viktoria-Varvara Palla, Georgios Karaolanis, Demetrios Moris, Aristides Antsaklis

引用次数: 7

Outcomes of diabetic and nondiabetic patients undergoing general and vascular surgery. 糖尿病和非糖尿病患者接受一般和血管手术的结果。

ISRN surgery Pub Date : 2013-12-26 DOI: 10.1155/2013/963930

Stephen Serio, John M Clements, Dawn Grauf, Aziz M Merchant

{"title":"Outcomes of diabetic and nondiabetic patients undergoing general and vascular surgery.","authors":"Stephen Serio, John M Clements, Dawn Grauf, Aziz M Merchant","doi":"10.1155/2013/963930","DOIUrl":"https://doi.org/10.1155/2013/963930","url":null,"abstract":"Aims. Preoperative diabetic and glycemic screening may or may not be cost effective. Although hyperglycemia is known to compromise surgical outcomes, the effect of a diabetic diagnosis on outcomes is poorly known. We examine the effect of diabetes on outcomes for general and vascular surgery patients. Methods. Data were collected from the Michigan Surgical Quality Collaborative for general or vascular surgery patients who had diabetes. Primary and secondary outcomes were 30-day mortality and 30-day overall morbidity, respectively. Binary logistic regression analysis was used to identify risk factors. Results. We identified 177,430 (89.9%) general surgery and 34,006 (16.1%) vascular surgery patients. Insulin and noninsulin diabetics accounted for 7.1% and 9.8%, respectively. Insulin and noninsulin dependent diabetics were not at increased risk for mortality. Diabetics are at a slight increased odds than non-diabetics for overall morbidity, and insulin dependent diabetics more so than non-insulin dependent. Ventilator dependence, 10% weight loss, emergent case, and ASA class were most predictive. Conclusions. Diabetics were not at increased risk for postoperative mortality. Insulin-dependent diabetics undergoing general or vascular surgery were at increased risk of overall 30-day morbidity. These data provide insight towards mitigating poor surgical outcomes in diabetic patients and the cost effectiveness of preoperative diabetic screening. ","PeriodicalId":89400,"journal":{"name":"ISRN surgery","volume":"2013 ","pages":"963930"},"PeriodicalIF":0.0,"publicationDate":"2013-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/963930","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32055544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 23

The effect of autologous platelet-rich plasma on bronchial stump tissue granulation after pneumonectomy: experimental study. 自体富血小板血浆对肺切除术后支气管残端组织肉芽形成的影响:实验研究。

ISRN surgery Pub Date : 2013-12-16 DOI: 10.1155/2013/864350

Eleftherios Spartalis, Periklis Tomos, Petros Konofaos, Grigorios Karagkiouzis, Georgia Levidou, Nikolaos Kavantzas, Alkistis Pantopoulou, Othon Michail, Despina Perrea, Gregory Kouraklis

{"title":"The effect of autologous platelet-rich plasma on bronchial stump tissue granulation after pneumonectomy: experimental study.","authors":"Eleftherios Spartalis, Periklis Tomos, Petros Konofaos, Grigorios Karagkiouzis, Georgia Levidou, Nikolaos Kavantzas, Alkistis Pantopoulou, Othon Michail, Despina Perrea, Gregory Kouraklis","doi":"10.1155/2013/864350","DOIUrl":"https://doi.org/10.1155/2013/864350","url":null,"abstract":"Objectives. Recent advances in perioperative management, antibiotics, and surgical materials, including mechanical staplers, have decreased the operative risk of pulmonary resection. However, bronchopleural fistula can still occur in some instances, the occurrence often being lethal. This study investigated whether platelet-rich plasma (PRP) promotes granulation of the bronchial stump after pneumonectomy. Methods. Ten pigs were randomized into two groups: (A) control or non-PRP group (pneumonectomy) and (B) PRP group (pneumonectomy and PRP application). PRP was obtained by spinning down the animal's own blood and collecting the buffy coat containing platelets and white blood cells. Results. Increased platelet concentration triggered the healing process. The percentage of granulation tissue formed at the stumps was significantly higher in the PRP group of animals. This observation was confirmed when statistical analysis using Mann-Whitney U test was performed (P = 0.0268). Conclusions. PRP is easily produced with minimal basic equipment and is useful in accelerating granulation of the bronchial stump, although the timing and optimum number of applications in humans require further study. Autologous PRP is a safe, feasible, and reliable new healing promoter with potential therapeutic effects. ","PeriodicalId":89400,"journal":{"name":"ISRN surgery","volume":"2013 ","pages":"864350"},"PeriodicalIF":0.0,"publicationDate":"2013-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/864350","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32055543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Quality of scar after total thyroidectomy: a single blinded randomized trial comparing octyl-cyanoacrylate and subcuticular absorbable suture. 甲状腺全切除术后疤痕的质量:一项比较氰基丙烯酸辛酯和皮下可吸收缝线的单盲随机试验。

ISRN surgery Pub Date : 2013-11-12 eCollection Date: 2013-01-01 DOI: 10.1155/2013/270953

Fabrizio Consorti, Rosaria Mancuso, Annalisa Piccolo, Eugenio Pretore, Alfredo Antonaci

{"title":"Quality of scar after total thyroidectomy: a single blinded randomized trial comparing octyl-cyanoacrylate and subcuticular absorbable suture.","authors":"Fabrizio Consorti, Rosaria Mancuso, Annalisa Piccolo, Eugenio Pretore, Alfredo Antonaci","doi":"10.1155/2013/270953","DOIUrl":"https://doi.org/10.1155/2013/270953","url":null,"abstract":"Objective. To compare the quality of resulting scar at 6 weeks after total thyroidectomy with the use of the tissue adhesive octyl-cyanoacrylate or subcuticular absorbable suture for the closure of cervicotomy. Material and Methods. There are 50 patients undergoing a cervicotomy for total thyroidectomy. Twenty-five patients were randomly assigned to closure with tissue adhesive and 25 with subcuticular absorbable suture. At week 6 the scar was evaluated by blinded assessors with the Italian version of POSAS questionnaire, a validated wound scale composed of an observer's and a patient's subscale. Results. Assessment of scar appearance showed a statistically significant difference (p = 0. 038) in favor of subcuticular suture with respect to tissue adhesive on observer's assessment. The difference on patients' self-assessment was not significant. A multivariate analysis of six qualitative features of scars showed a significant influence on assessment for hyperpigmentation and relief of scar. The Italian version of POSAS proved to be reliable. Conclusion. Though tissue adhesive represents a valid method of skin closure, subcuticular absorbable suture provides a better aesthetic outcome in small cervical incisions in the early phase after thyroid surgery. ","PeriodicalId":89400,"journal":{"name":"ISRN surgery","volume":"2013 ","pages":"270953"},"PeriodicalIF":0.0,"publicationDate":"2013-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/270953","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31943991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 25

Is surgery in the elderly for oesophageal cancer justifiable? Results from a single centre. 老年人食管癌手术治疗是否合理?来自单一中心的结果。

ISRN surgery Pub Date : 2013-09-24 eCollection Date: 2013-01-01 DOI: 10.1155/2013/609252

A Mirza, S Pritchard, I Welch

{"title":"Is surgery in the elderly for oesophageal cancer justifiable? Results from a single centre.","authors":"A Mirza, S Pritchard, I Welch","doi":"10.1155/2013/609252","DOIUrl":"https://doi.org/10.1155/2013/609252","url":null,"abstract":"Aims. Advanced age is an identified risk factor for patients undergoing oncological surgical resection. The surgery for oesophageal cancer is associated with significant morbidity and mortality. Our aim was to study the operative management of elderly patients (≥70 years) at a single institute. Methods. The data was collected from 206 patients who have undergone operative resection of oesophageal cancer. The demographic, operative, histological, and postoperative follow-up of all patients were analysed. Results. A total of 46 patients of ≥70 years who had surgical resection for oesophageal cancer were identified. Patients ≥70 years had poor overall survival (P = 0.00). Also elderly patients with nodal involvement had poor survival (P = 0.04). Age at the time of surgery had no impact on the incidence of postoperative complication and inpatient mortality. Both the univariate and multivariate analyses showed age, nodal stage, and positive resection margins as independent prognostic factors for patients undergoing surgery for oesophageal cancer. Conclusions. Advanced age is associated with poor outcome following oesophageal resection. However, the optimisation of both preoperative and postoperative care can significantly improve outcomes. The decision of operative management should be individualised. Age should be considered as one of the factors in surgical resection of oesophageal cancer in the elderly patients. ","PeriodicalId":89400,"journal":{"name":"ISRN surgery","volume":"2013 ","pages":"609252"},"PeriodicalIF":0.0,"publicationDate":"2013-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/609252","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31843986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Operative treatment of hepatic hydatid cysts: a single center experience in Israel, a nonendemic country. 肝包虫病的手术治疗:在以色列，一个非地方性国家的单中心经验。

ISRN surgery Pub Date : 2013-09-23 eCollection Date: 2013-01-01 DOI: 10.1155/2013/276807

Daniel Maoz, Franklin Greif, Jacob Chen

{"title":"Operative treatment of hepatic hydatid cysts: a single center experience in Israel, a nonendemic country.","authors":"Daniel Maoz, Franklin Greif, Jacob Chen","doi":"10.1155/2013/276807","DOIUrl":"https://doi.org/10.1155/2013/276807","url":null,"abstract":"Background. Hydatid cyst disease is a zoonosis caused by Echinococcus genera. The disease is endemic to certain rural areas in the world. Operative treatment is the main component in curing hydatid cysts of the liver. Objective. Describing the unique characteristics of the hydatid cyst patients in Israel, a nonendemic country. Methods. Data was collected form 29 patients treated operatively in Rabin Medical Center from 1994 to 2007. Results. The study included 18 females and 11 males with an average age of 54.9 years. Fifty-two% of the patients immigrated as children from Arab countries to Israel, 21% were Arab-Israelis leaving in the north and center of Israel, and 24% immigrated from the former Communist Bloc. Pericystectomy was performed in 20/29, and cyst unroofing was performed in 9/29. Hydatid cysts average size was 10.7 cm, and the cysts were located in the right or left or involved both lobes in 62%, 28%, and 10% of the lesions, respectively. Postoperative mortality occurred in one case, and severe morbidity occurred in 4 patients. Conclusions. Hydatid cyst disease in Israel is uncommon and is mostly seen in distinct 3 demographic groups. Despite the relatively low patient volume, good results in terms of morbidity, mortality, and recurrence were achieved. ","PeriodicalId":89400,"journal":{"name":"ISRN surgery","volume":" ","pages":"276807"},"PeriodicalIF":0.0,"publicationDate":"2013-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/276807","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40279029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Postmastectomy radiation therapy: an overview for the practicing surgeon. 乳房切除术后放射治疗：执业外科医生概览。

ISRN surgery Pub Date : 2013-09-11 DOI: 10.1155/2013/212979

Reshma Jagsi

{"title":"Postmastectomy radiation therapy: an overview for the practicing surgeon.","authors":"Reshma Jagsi","doi":"10.1155/2013/212979","DOIUrl":"10.1155/2013/212979","url":null,"abstract":"Locoregional control of breast cancer is the shared domain and responsibility of surgeons and radiation oncologists. Because surgeons are often the first providers to discuss locoregional control and recurrence risks with patients and because they serve in a key gatekeeping role as referring providers for radiation therapy, a sophisticated understanding of the evidence regarding radiotherapy in breast cancer management is essential for the practicing surgeon. This paper synthesizes the complex and evolving evidence regarding the role of radiation therapy after mastectomy. Although substantial evidence indicates that radiation therapy can reduce the risk of locoregional failure after mastectomy (with a relative reduction of risk of approximately two-thirds), debate persists regarding the specific subgroups who have sufficient risks of residual microscopic locoregional disease after mastectomy to warrant treatment with radiation. This paper reviews the evidence available to guide appropriate referral and patient decision making, with special attention to areas of controversy, including patients with limited nodal disease, those with large tumors but negative nodes, node-negative patients with high risk features, patients who have received systemic chemotherapy in the neoadjuvant setting, and patients who may wish to integrate radiation therapy with breast reconstruction surgery. ","PeriodicalId":89400,"journal":{"name":"ISRN surgery","volume":"2013 ","pages":"212979"},"PeriodicalIF":0.0,"publicationDate":"2013-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31792473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Completely resected n0 non-small cell lung cancer: prognostic factors affecting long-term survival. 完全切除非小细胞肺癌:影响长期生存的预后因素。

ISRN surgery Pub Date : 2013-08-29 eCollection Date: 2013-01-01 DOI: 10.1155/2013/175304

Apichat Tantraworasin, Somcharoen Saeteng, Nirush Lertprasertsuke, Nuttapon Arayawudhikule, Choosak Kasemsarn, Jayanton Patumanond

{"title":"Completely resected n0 non-small cell lung cancer: prognostic factors affecting long-term survival.","authors":"Apichat Tantraworasin, Somcharoen Saeteng, Nirush Lertprasertsuke, Nuttapon Arayawudhikule, Choosak Kasemsarn, Jayanton Patumanond","doi":"10.1155/2013/175304","DOIUrl":"https://doi.org/10.1155/2013/175304","url":null,"abstract":"Background. Although early stage non-small cell lung cancer (NSCLC) has an excellent outcome and correlated with good long-term survival, up to 15 percent of patients still relapse postoperatively and die. This study is conducted to identify prognostic factors that may affect the long-term survival in completely resected N0 NSCLC. Methods. Medical records of 124 patients with completely resected N0 NSCLC were retrospectively reviewed. Prognostic factors affecting long-term survival were analyzed by the Kaplan-Meier method and Cox proportional hazards analysis. Results. Overall five-year survival rate was 48 percent. Multivariable analysis revealed stage of disease, tumor necrosis, tumor recurrence, brain metastasis, adrenal metastases, and skin metastases as significant prognostic factors affecting long-term survival. The hazard ratio (HR) of tumor necrosis, tumor recurrence, brain metastasis, adrenal metastases, and skin metastases was 2.0, 2.3, 7.6, 4.1, and 8.3, respectively, and all P values were less than 0.001. Conclusions. Our study shows stage of disease, tumor necrosis, tumor recurrence, brain metastasis, adrenal metastasis, and skin metastasis as the independent prognostic factors of long-term survival in pathological N0 NSCLC. Early stage NSCLC patients without nodal involvement or presented with tumor necrosis should benefit from adjuvant chemotherapy, and sites of metastasis could predict the long-term survival as described. ","PeriodicalId":89400,"journal":{"name":"ISRN surgery","volume":"2013 ","pages":"175304"},"PeriodicalIF":0.0,"publicationDate":"2013-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/175304","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31764755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9