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The Effects of Pancreas Transplantation on the Course of Secondary Diabetic Complications 胰腺移植对继发性糖尿病并发症病程的影响
Graft (Georgetown, Tex.) Pub Date : 2002-07-01 DOI: 10.1177/1522162802005005005
P. Fiorina, A. Secchi
{"title":"The Effects of Pancreas Transplantation on the Course of Secondary Diabetic Complications","authors":"P. Fiorina, A. Secchi","doi":"10.1177/1522162802005005005","DOIUrl":"https://doi.org/10.1177/1522162802005005005","url":null,"abstract":"","PeriodicalId":89378,"journal":{"name":"Graft (Georgetown, Tex.)","volume":"31 1","pages":"303-307"},"PeriodicalIF":0.0,"publicationDate":"2002-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80613036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do Sex and Ethnicity Influence Drug Pharmacokinetics in Solid Organ Transplantation 性别和种族是否影响实体器官移植的药物代动力学
Graft (Georgetown, Tex.) Pub Date : 2002-07-01 DOI: 10.1177/1522162802005005003
A. Mathis, G. Friedman, G. Knipp
{"title":"Do Sex and Ethnicity Influence Drug Pharmacokinetics in Solid Organ Transplantation","authors":"A. Mathis, G. Friedman, G. Knipp","doi":"10.1177/1522162802005005003","DOIUrl":"https://doi.org/10.1177/1522162802005005003","url":null,"abstract":"A number of reports have identified differences in drug pharmacokinetics and pharmacodynamics between males and females, and between patients of different ethnicity. These differences are observed in both solid organ transplant recipients and in nontransplant patients. This review summarizes the pharmacokinetic differences thought to be dependent on sex and ethnicity noted with immunosuppressive agents commonly used in transplantation. This manuscript also touches on how these differences may translate into observed drug interactions. Furthermore, potential factors underlying the sex and ethnicity differences are evaluated. Current evidence points to differences in drug-metabolizing enzymes, transporters, cytokines, and environmental influences to account for the observed heterogeneity in drug response. Many of these factors seem to be under genetic control, and thus areas for further research are suggested.","PeriodicalId":89378,"journal":{"name":"Graft (Georgetown, Tex.)","volume":"19 1","pages":"294-302"},"PeriodicalIF":0.0,"publicationDate":"2002-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84428767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Cryopreservation of Human Pancreatic Islets 人胰岛的低温保存
Graft (Georgetown, Tex.) Pub Date : 2002-07-01 DOI: 10.1177/1522162802005005001
J. Lakey, P. Burridge, R. Rajotte
{"title":"Cryopreservation of Human Pancreatic Islets","authors":"J. Lakey, P. Burridge, R. Rajotte","doi":"10.1177/1522162802005005001","DOIUrl":"https://doi.org/10.1177/1522162802005005001","url":null,"abstract":"","PeriodicalId":89378,"journal":{"name":"Graft (Georgetown, Tex.)","volume":"13 1","pages":"266-276"},"PeriodicalIF":0.0,"publicationDate":"2002-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85270584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Genetic Engineering of Dendritic Cells to Enhance Their Tolerogenic Potential 增强树突状细胞耐受性的基因工程
Graft (Georgetown, Tex.) Pub Date : 2002-07-01 DOI: 10.1177/1522162802005005006
Lina L. Lu, A. Thomson
{"title":"Genetic Engineering of Dendritic Cells to Enhance Their Tolerogenic Potential","authors":"Lina L. Lu, A. Thomson","doi":"10.1177/1522162802005005006","DOIUrl":"https://doi.org/10.1177/1522162802005005006","url":null,"abstract":"","PeriodicalId":89378,"journal":{"name":"Graft (Georgetown, Tex.)","volume":"10 1","pages":"308-314"},"PeriodicalIF":0.0,"publicationDate":"2002-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72859582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Host Defense Mechanisms with Special Reference to Chemokines and Viral Infections 宿主防御机制与趋化因子和病毒感染的特殊关系
Graft (Georgetown, Tex.) Pub Date : 2002-07-01 DOI: 10.1177/1522162802005005002
S. Mahalingam
{"title":"Host Defense Mechanisms with Special Reference to Chemokines and Viral Infections","authors":"S. Mahalingam","doi":"10.1177/1522162802005005002","DOIUrl":"https://doi.org/10.1177/1522162802005005002","url":null,"abstract":"An important role for the mammalian body is to guard against infection by pathogenic micro-organisms. There are five main classes of pathogens, namely, viruses, bacteria, parasites, fungi, and worms. The complex relationships between these pathogenic micro-organisms and the vertebrate host are perhaps most clearly understood for viruses. The survival of viruses depends on the survival of susceptible hosts. In recent years, chemokines have been shown to play an integral role in the recruitment of cells to sites of infection, thus mediating the healing process. This review will provide an overview of immune responses with reference to viral infections and chemokines. REVIEWS","PeriodicalId":89378,"journal":{"name":"Graft (Georgetown, Tex.)","volume":"82 1","pages":"277-293"},"PeriodicalIF":0.0,"publicationDate":"2002-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76058922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
An Antigen-Independent Important Hormone: Intrarenal Angiotensin II (AII) as a Key to Understanding Chronic Allograft Nephropathy 一种不依赖抗原的重要激素:肾内血管紧张素II (AII)是理解慢性同种异体移植肾病的关键
Graft (Georgetown, Tex.) Pub Date : 2002-06-01 DOI: 10.1177/152216280200500402
B. Becker, L. Jacobson, D. Hullett
{"title":"An Antigen-Independent Important Hormone: Intrarenal Angiotensin II (AII) as a Key to Understanding Chronic Allograft Nephropathy","authors":"B. Becker, L. Jacobson, D. Hullett","doi":"10.1177/152216280200500402","DOIUrl":"https://doi.org/10.1177/152216280200500402","url":null,"abstract":"Chronic allograft nephropathy (CAN) is a multifactorial lesion. There has been a gradu-ally increasing recognition of the importance of antigen-independent factors influencingthe development and progression of CAN. One important antigen-independent hor-mone in this setting is angiotensin II (AII), which is associated with progressive kidneydisease. Although the pathogenesis of native kidney disease may differ from CAN, thechronic progressive nature of both entities raises the hypothesis that AII also has a rolein CAN. However, AII also serves as a theoretical focal point, linking many of the factorsinvolved in CAN. Fortunately, we have therapies, angiotensin converting enzyme in-hibitors (ACE-I), and type 1 angiotensin II receptor (AT","PeriodicalId":89378,"journal":{"name":"Graft (Georgetown, Tex.)","volume":"121 5 1","pages":"199-204"},"PeriodicalIF":0.0,"publicationDate":"2002-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75176768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Graft-versus-Host Disease and Graft-versus-Leukemic Effect in Allogeneic Bone Marrow Transplantation: Role of Interferon-{gamma} 同种异体骨髓移植中的移植物抗宿主病和移植物抗白血病效应:干扰素-{γ}的作用
Graft (Georgetown, Tex.) Pub Date : 2002-06-01 DOI: 10.1177/152216280200500408
Yong-Guang Yang, M. Sykes
{"title":"Graft-versus-Host Disease and Graft-versus-Leukemic Effect in Allogeneic Bone Marrow Transplantation: Role of Interferon-{gamma}","authors":"Yong-Guang Yang, M. Sykes","doi":"10.1177/152216280200500408","DOIUrl":"https://doi.org/10.1177/152216280200500408","url":null,"abstract":"","PeriodicalId":89378,"journal":{"name":"Graft (Georgetown, Tex.)","volume":"176 1","pages":"250-255"},"PeriodicalIF":0.0,"publicationDate":"2002-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74961036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Prothrombogenic microvasculature and transplant outcome 血栓形成前微血管和移植结果
Graft (Georgetown, Tex.) Pub Date : 2002-06-01 DOI: 10.1177/152216280200500404
C. Labarrere, D. Nelson, Steven J. Miller
{"title":"Prothrombogenic microvasculature and transplant outcome","authors":"C. Labarrere, D. Nelson, Steven J. Miller","doi":"10.1177/152216280200500404","DOIUrl":"https://doi.org/10.1177/152216280200500404","url":null,"abstract":"","PeriodicalId":89378,"journal":{"name":"Graft (Georgetown, Tex.)","volume":"45 1","pages":"212-222"},"PeriodicalIF":0.0,"publicationDate":"2002-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77807611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Steroid Sparing after Kidney and Pancreas Transplantation 肾和胰腺移植后类固醇保留
Graft (Georgetown, Tex.) Pub Date : 2002-06-01 DOI: 10.1177/152216280200500406
A. Matas
{"title":"Steroid Sparing after Kidney and Pancreas Transplantation","authors":"A. Matas","doi":"10.1177/152216280200500406","DOIUrl":"https://doi.org/10.1177/152216280200500406","url":null,"abstract":"","PeriodicalId":89378,"journal":{"name":"Graft (Georgetown, Tex.)","volume":"29 1","pages":"232-236"},"PeriodicalIF":0.0,"publicationDate":"2002-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72481475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Why Do Kidneys from Older Donors Display an Inferior Survival 为什么老年捐赠者的肾脏存活率较低
Graft (Georgetown, Tex.) Pub Date : 2002-06-01 DOI: 10.1177/152216280200500401
L. Paul, J. W. Fijter
{"title":"Why Do Kidneys from Older Donors Display an Inferior Survival","authors":"L. Paul, J. W. Fijter","doi":"10.1177/152216280200500401","DOIUrl":"https://doi.org/10.1177/152216280200500401","url":null,"abstract":"","PeriodicalId":89378,"journal":{"name":"Graft (Georgetown, Tex.)","volume":"15 1","pages":"194-198"},"PeriodicalIF":0.0,"publicationDate":"2002-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73902320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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