K. Pietzner, M. Passler, Maximilian Krafft, S. Alavi, R. Armbrust, Aarne Feldheiser, J. Sehouli
{"title":"2022-RA-1438-ESGO Safety of total paracentesis in patients with malignant ascites from ovarian cancer: Results from the prospective, randomised ATLANTIS-trial","authors":"K. Pietzner, M. Passler, Maximilian Krafft, S. Alavi, R. Armbrust, Aarne Feldheiser, J. Sehouli","doi":"10.1136/ijgc-2022-esgo.714","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.714","url":null,"abstract":"","PeriodicalId":89343,"journal":{"name":"Clinical ovarian cancer and other gynecologic malignancies","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76904591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"2022-RA-643-ESGO Mucinous ovarian cancers – a single institution analysis of clinicopathologic profile and survival outcomes","authors":"D. Bose, P. Rema","doi":"10.1136/ijgc-2022-esgo.533","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.533","url":null,"abstract":"","PeriodicalId":89343,"journal":{"name":"Clinical ovarian cancer and other gynecologic malignancies","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85983228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Hruda, V. Hlaváč, P. Holý, K. Šeborová, R. Vaclavikova, M. Mrhalová, Petr Černaj, J. Bouda, P. Souček, L. Rob
{"title":"2022-RA-861-ESGO Transcriptome and genetic profile of epithelial ovarian carcinoma patients sensitive and resistant to platinum derivatives","authors":"M. Hruda, V. Hlaváč, P. Holý, K. Šeborová, R. Vaclavikova, M. Mrhalová, Petr Černaj, J. Bouda, P. Souček, L. Rob","doi":"10.1136/ijgc-2022-esgo.578","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.578","url":null,"abstract":"","PeriodicalId":89343,"journal":{"name":"Clinical ovarian cancer and other gynecologic malignancies","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84737767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mihaela Asp, Ebba Peber, P. Kannisto, A. Måsbäck, S. Malander
{"title":"2022-RA-245-ESGO Ovarian tumor frozen section, a multidisciplinary affair","authors":"Mihaela Asp, Ebba Peber, P. Kannisto, A. Måsbäck, S. Malander","doi":"10.1136/ijgc-2022-esgo.487","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.487","url":null,"abstract":"","PeriodicalId":89343,"journal":{"name":"Clinical ovarian cancer and other gynecologic malignancies","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84896866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Eriksson, Ragni K Idland, Larissa E. Hoffmann, T. Paulsen, Yun Wang, T. S. Jensen, Brynhildur Eyjólfsdóttir, O. Solheim, Pernille Bjerre Trent, B. Davidson, A. Dørum, M. Småstuen
{"title":"2022-RA-1306-ESGO Effect of the COVID-19 pandemic on primary therapy and oncologic outcomes in women with advanced stage tubo-ovarian carcinoma in a tertiary cancer center","authors":"A. Eriksson, Ragni K Idland, Larissa E. Hoffmann, T. Paulsen, Yun Wang, T. S. Jensen, Brynhildur Eyjólfsdóttir, O. Solheim, Pernille Bjerre Trent, B. Davidson, A. Dørum, M. Småstuen","doi":"10.1136/ijgc-2022-ESGO.683","DOIUrl":"https://doi.org/10.1136/ijgc-2022-ESGO.683","url":null,"abstract":"2022-RA-1306-ESGO Table 1Patient, tumor and treatment characteristicsResultsThere were 354 (76%) and 114 (24%) women in the pre-Covid and Covid cohorts, respectively. Demographics did not differ between cohorts (table 1). At multidisciplinary team evaluations there were no differences in allocation to primary surgery (PDS), interval surgery (IDS) or chemotherapy only (CT) between cohorts. Surgical complexity scores at PDS and IDS were similar in both cohorts. At PDS significantly more women in the covid cohort had residual disease <10 mm. Type and amount of chemotherapy did not differ between cohorts. Significantly more women in the Covid cohort received PARPi maintenance therapy. A significantly higher cumulative incidence of recurrence was found for the covid cohort (p<0.0003), figure 1a. For women undergoing exploratory laparotomy or IDS the risk of recurrence was higher in the Covid cohort than the pre-Covid cohort during initial 18 months after diagnosis, for IDS HR=2.75 [95% CI, 1.45–5.2], figure 1b.ConclusionDespite equal surgical capacity and favorable prognostic characteristics, women with advanced stage HGSC diagnosed during the Covid pandemic had a significantly higher risk of recurrence when compared to pre-covid cohort, particularly for women undergoing IDS.","PeriodicalId":89343,"journal":{"name":"Clinical ovarian cancer and other gynecologic malignancies","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85280659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Li Sun, M. Sobočan, Isabel V. Rodriguez, Xiaohui Wei, Ashwin Kalra, S. Oxley, M. Sideris, R. Morgan, D. Chandrasekaran, K. Rust, P. Spiliopoulou, Rowan E Miller, Shanthini M. Crusz, M. Lockley, N. Singh, A. Faruqi, Laura Casey, E. Brockbank, S. Phadnis, T. Mills-Baldock, F. El-Khouly, L. Jenkins, A. Wallace, Munaza Ahmed, Ajith Kumar, E. Swisher, C. Gourley, B. Norquist, D. Gareth Evans, R. Legood, R. Manchanda
{"title":"2022-RA-1310-ESGO Cost-effectiveness of unselected multigene germline and somatic genetic testing for epithelial ovarian cancer","authors":"Li Sun, M. Sobočan, Isabel V. Rodriguez, Xiaohui Wei, Ashwin Kalra, S. Oxley, M. Sideris, R. Morgan, D. Chandrasekaran, K. Rust, P. Spiliopoulou, Rowan E Miller, Shanthini M. Crusz, M. Lockley, N. Singh, A. Faruqi, Laura Casey, E. Brockbank, S. Phadnis, T. Mills-Baldock, F. El-Khouly, L. Jenkins, A. Wallace, Munaza Ahmed, Ajith Kumar, E. Swisher, C. Gourley, B. Norquist, D. Gareth Evans, R. Legood, R. Manchanda","doi":"10.1136/ijgc-2022-esgo.685","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.685","url":null,"abstract":"","PeriodicalId":89343,"journal":{"name":"Clinical ovarian cancer and other gynecologic malignancies","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86845321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"2022-RA-1517-ESGO Wroclaw comprehensive cancer centre 100 months experience in cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS+HIPEC) in patients with peritoneal carcinomatosis – indications and complications of the procedure","authors":"K. Szewczyk, M. Jedryka, M. Bębenek","doi":"10.1136/ijgc-2022-esgo.734","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.734","url":null,"abstract":"impact 5-year DFS (p=0.552). At univari-ate analysis the only significant variable affecting DFS was the performance of lymphadenectomy (HR:0.388; 95% CI:0.174 – 0.866;p=0.021). Abstract 2022-RA-1515-ESGO Figure 1 Conclusion In a retrospective multicenter series of low-grade endometrioid ovarian cancers apparently confined to the ovary, lymphadenectomy appeared to be associated with improved DFS. Adjuvant chemotherapy did not impact DFS. Nevertheless, the present results derive from a retrospective uncontrolled study, in which the indication for or against lym-phadenectomy/adjuvant chemotherapy was not prospectively defined, causing potential significant selection bias.","PeriodicalId":89343,"journal":{"name":"Clinical ovarian cancer and other gynecologic malignancies","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84787463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Nishio, M. Yunokawa, Koji Matsumoto, K. Takehara, K. Hasegawa, Y. Hirashima, H. Kato, H. Ikezawa, Maiko Nomoto, S. Hayato, Yohei Otake, Takuma Miura, K. Yonemori
{"title":"2022-RA-680-ESGO Safety and efficacy of MORAb-202 in patients with platinum-resistant ovarian cancer: results from the expansion part of a phase 1 trial in Japan","authors":"S. Nishio, M. Yunokawa, Koji Matsumoto, K. Takehara, K. Hasegawa, Y. Hirashima, H. Kato, H. Ikezawa, Maiko Nomoto, S. Hayato, Yohei Otake, Takuma Miura, K. Yonemori","doi":"10.1136/ijgc-2022-esgo.543","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.543","url":null,"abstract":"","PeriodicalId":89343,"journal":{"name":"Clinical ovarian cancer and other gynecologic malignancies","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81761460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tjadina Arndt, R. Chekerov, K. Pietzner, I. Yalcinkaya, U. Canzler, P. Wimberger, H. Strauß, S. Mahner, L. Woelber, N. de Gregorio, U. Hacker, E. V. Abel, R. Richter, J. Sehouli
{"title":"2022-RA-1725-ESGO Pazopanib with Topotecan weekly for patients with platinum-resistant or intermediate-sensitive recurrent ovarian cancer- results of a multicentre NOGGO phase I and II study (TOPAZ)","authors":"Tjadina Arndt, R. Chekerov, K. Pietzner, I. Yalcinkaya, U. Canzler, P. Wimberger, H. Strauß, S. Mahner, L. Woelber, N. de Gregorio, U. Hacker, E. V. Abel, R. Richter, J. Sehouli","doi":"10.1136/ijgc-2022-esgo.779","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.779","url":null,"abstract":"2022-RA-1715-ESGO Table 1 Univariate analysis of the risk of recurrence after the first surgery Factor Category Odds Ratio (IC 95%) P value Histology Serous 4 (0.6744003 23.72478) 0.10","PeriodicalId":89343,"journal":{"name":"Clinical ovarian cancer and other gynecologic malignancies","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81396774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ben Johnson, M. Cannon, J. Vandenbroucque, Yelena Parada, K. Lucero
{"title":"2022-RA-1111-ESGO Case studies as a valuable tool to improve physician competence regarding identification of patients and selection of treatment for newly diagnosed advanced ovarian cancer","authors":"Ben Johnson, M. Cannon, J. Vandenbroucque, Yelena Parada, K. Lucero","doi":"10.1136/ijgc-2022-esgo.640","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.640","url":null,"abstract":"","PeriodicalId":89343,"journal":{"name":"Clinical ovarian cancer and other gynecologic malignancies","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83624335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}