2022-RA-1517-ESGO Wroclaw comprehensive cancer centre 100 months experience in cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS+HIPEC) in patients with peritoneal carcinomatosis – indications and complications of the procedure

K. Szewczyk, M. Jedryka, M. Bębenek
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Abstract

impact 5-year DFS (p=0.552). At univari-ate analysis the only significant variable affecting DFS was the performance of lymphadenectomy (HR:0.388; 95% CI:0.174 – 0.866;p=0.021). Abstract 2022-RA-1515-ESGO Figure 1 Conclusion In a retrospective multicenter series of low-grade endometrioid ovarian cancers apparently confined to the ovary, lymphadenectomy appeared to be associated with improved DFS. Adjuvant chemotherapy did not impact DFS. Nevertheless, the present results derive from a retrospective uncontrolled study, in which the indication for or against lym-phadenectomy/adjuvant chemotherapy was not prospectively defined, causing potential significant selection bias.
在腹膜癌患者的细胞减少手术和腹腔热化疗(CRS+HIPEC)方面有100个月的经验-手术的适应症和并发症
影响5年DFS (p=0.552)。在单因素分析中,影响DFS的唯一显著变量是淋巴结切除术的表现(HR:0.388;95% CI:0.174 - 0.866;p=0.021)。结论在一项明显局限于卵巢的低级别子宫内膜样卵巢癌的多中心回顾性研究中,淋巴结切除术似乎与改善DFS有关。辅助化疗对DFS无影响。然而,目前的结果来自一项回顾性的非对照研究,其中淋巴结切除术/辅助化疗的适应症没有前瞻性定义,导致潜在的重大选择偏倚。
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