{"title":"Dosimetric evaluation of radiation dose rate effect in respiratory gated intensity modulated radiation therapy.","authors":"C Khamfongkhruea, C Tannanonta, S Thongsawad","doi":"10.2349/biij.8.1.e5","DOIUrl":"https://doi.org/10.2349/biij.8.1.e5","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the dosimetric accuracy of the sliding window gated IMRT compared with the static treatment, using varying dose rates.</p><p><strong>Materials and methods: </strong>This study measured changes in output and diode array response with changing dose rate, verified the precision of the motion table, and measured changes in dose distribution accuracy with film and diodes at two depths with changing dose rate. During 4DCT (4 Dimensional Computed Tomography), the patient's respiratory signals and target motion were recorded and imported to the XY4D simulation table of SUN NUCLEAR Corporation to simulate the patient's respiration and tumour motion. A single field of each sliding window IMRT plan with 30º wedge and one for lung cancer were used in this study. Three irradiating conditions, static and moving target with and without gating, were applied to both plans.</p><p><strong>Results: </strong>The standard deviations of output, with the dose rates changing from 300-600 MU/min, were 0.065 cGy and 0.169 cGy for the ionisation chamber and diode, respectively. The verification of the motion table shows very good precision with 9.98 ± 0.02 cm (true value = 10.0 cm). The measurements by MapCheck show the gamma index of the planned absolute dose distribution in static and moving targets with gating, resulting in more than 96% passing for all dose rates. The absolute dose distribution measured by film for the static target was agreeable with the value of moving target with gating.</p><p><strong>Conclusion: </strong>The sliding window gated IMRT technique is able to deliver an accurate dose to a moving target with the dose rate of 300-600 MU/min that is suitable for clinical treatment.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"8 1","pages":"e5"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.8.1.e5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30897037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fine needle aspiration of lung lesion: Lateral and transpectoral approach.","authors":"K Smith","doi":"10.2349/biij.8.1.e2","DOIUrl":"https://doi.org/10.2349/biij.8.1.e2","url":null,"abstract":"<p><p>A 69 year-old man presented with an incidental finding on radiograph of a lesion in the left upper lobe. CT indicated it was likely to be a neoplasm and CT-guided FNA was requested. The lesion was located medial to the scapula so a creative approach was utilised to gain access to the lesion. This study discusses the approach used and why it reduced patient risk compared to a more conventional procedure. The sample was positive for neoplasm and there were no complications arising from the procedure.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"8 1","pages":"e2"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.8.1.e2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30897034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dialysis catheter fibrin sheath stripping: a useful technique after failed catheter exchange.","authors":"Af Mohamad Ali, E Uhwut, Sk Liew","doi":"10.2349/biij.8.1.e8","DOIUrl":"https://doi.org/10.2349/biij.8.1.e8","url":null,"abstract":"<p><p>Fibrin sheath formation around long-term haemodialysis catheter is a common cause of failed dialysis access. Treatment options include pharmacological and mechanical methods. This paper reports a case of failed dialysis access due to fibrin sheath encasement. Pharmacologic thrombolysis, mechanical disruption using guide wire and catheter exchange had failed to address the issue. Eventually, fibrin sheath stripping using the loop snare technique was able to successfully restore the catheter function.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"8 1","pages":"e8"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.8.1.e8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30897040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Social radiology: Where to now?","authors":"Elm Ho","doi":"10.2349/biij.8.1.e9","DOIUrl":"10.2349/biij.8.1.e9","url":null,"abstract":"<p><p>Radiology is a relatively high-cost and high-maintenance aspect of medicine. Expertise is constantly required, from acquisition to its use and quality assurance programmes. However, it is an integral part of healthcare practice, from disease diagnosis, surveillance and prevention to treatment monitoring. It is alarming that two thirds of the world is deficient in or lacks even basic diagnostic imaging. Developing and underdeveloped countries need help in improving medical imaging. Help is coming from various organisations, which are extending hands-on teaching and imparting knowledge, as well as training trainers to increase the pool of skilled practitioners in the use of imaging equipment and other aspects of radiology services. The scene for social radiology is changing and set to positively impact the world in the (near) future.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"8 1","pages":"e9"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30897041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiological emergencies and the medical physicist.","authors":"W Hendee","doi":"10.2349/biij.7.4.e29","DOIUrl":"https://doi.org/10.2349/biij.7.4.e29","url":null,"abstract":"The widespread damage and loss of life caused by the March 11th earthquake-generated tsunami in Japan, and the resulting emergency at the Fukushima—Daiichi nuclear power facility, raise once again the question of the role of knowledgeable civilians in responding to public health emergencies. In the case of a radiological emergency, medical physicists are among the more knowledgeable individuals in the private sector with regard to several relevant issues including radiation exposures and risks, radioactive contamination, and the fear of radiation that make management of a radiological emergency so difficult. The challenges for medical physicists are to know the consequences of radiation exposure and radioactive contamination, to separate fantasy from fact in dealing with these consequences, and to address the consequences in a manner that instils confidence rather than fear in those who are less knowledgeable. All medical physicists should be knowledgeable about radiological emergencies and prepared to respond to an emergency if one occurs in their vicinity. Four types of radiological emergency would potentially expose large numbers of people to high amounts of radiation and require an emergency response that involves medical physicists. These types of events are (1) the detonation of a nuclear weapon or improvised nuclear device , with an impact on the order of the Hiroshima and Nagasaki nuclear bombs, or possibly larger; (2) a crisis at a nuclear power plant, including a possible core meltdown and the release of radioactive contamination, such as is possible at the Fukushima— Daiichi nuclear complex; (3) activation of an explosive radiological dispersal device, sometimes termed a ―dirty bomb‖; and (4) placement of a hidden radioactive source in a highly populated area where many people could be exposed to substantial doses of radiation. Somewhat less threatening but still of major concern is a transportation accident involving a cargo with high levels of radioactivity. One or more of these events is conceivable anywhere in the world. Should one occur, medical physicists in the vicinity will be recruited as experts in the management of the after-effects of the event, including the possible exposure of many individuals to radiation and/or radioactive contamination. The question every medical physicist should ask is ―How prepared am I to respond if called upon to help in the management of a radiological emergency?‖ There are several information sources that a medical physicist can access to expand his/her preparedness for a radiological emergency. A good place to start is a …","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"7 4","pages":"e29"},"PeriodicalIF":0.0,"publicationDate":"2011-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.7.4.e29","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30414651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epidural haemorrhage during embolisation: a rare complication of intra-arterial embolisation of vertebral metastases.","authors":"H Hashim, Ka Abdul Kadir","doi":"10.2349/biij.7.4.e26","DOIUrl":"https://doi.org/10.2349/biij.7.4.e26","url":null,"abstract":"<p><p>Pre-operative embolisation of vertebral metastases has been known to effectively devascularise hypervascular vertebral tumours and to reduce intra-operative bleeding. However, the complications that occur during the procedure are rarely reported. This case study attempts to highlight one rare complication, which is epidural tumoural haemorrhage intra-procedure. It may occur due to the fragility of the tumour and presence of neovascularisation. A small arterial dissection may also have occurred due to a slightly higher pressure exerted during injection of embolising agent. Haemostasis was secured via injection of Histoacryl into the area of haemorrhage. The patient was able to undergo the decompression surgery and suffered no direct complication from the haemorrhage.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"7 4","pages":"e26"},"PeriodicalIF":0.0,"publicationDate":"2011-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.7.4.e26","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30414647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasound evaluation of penile fractures.","authors":"Sg Kachewar, Ds Kulkarni","doi":"10.2349/biij.7.4.e27","DOIUrl":"https://doi.org/10.2349/biij.7.4.e27","url":null,"abstract":"<p><p>This short case report discusses the various aspects of penile fracture, which is a rare entity. Nevertheless, the incidence of penile fractures is on the rise due to the increased use of performance-enhancing drugs. An individual with a penile fracture should seek immediate medical referral. Prompt diagnosis and management is necessary to prevent undesirable after-effects as discussed. Emphasis is made on how imaging with ultrasound enables a quick and complete assessment of this mishap.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"7 4","pages":"e27"},"PeriodicalIF":0.0,"publicationDate":"2011-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.7.4.e27","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30414648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I Chitapanarux, T Chitapanarux, E Tharavichitkul, S Mayurasakorn, P Siriwittayakorn, S Yamada, V Lorvidhaya
{"title":"A phase II study of oxaliplatin with 5-FU/folinic acid and concomitant radiotherapy as a preoperative treatment in patients with locally advanced rectal cancer.","authors":"I Chitapanarux, T Chitapanarux, E Tharavichitkul, S Mayurasakorn, P Siriwittayakorn, S Yamada, V Lorvidhaya","doi":"10.2349/biij.7.4.e25","DOIUrl":"https://doi.org/10.2349/biij.7.4.e25","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the activity and safety of adding oxaliplatin to a standard chemoradiotherapy schema, including 5-fluorouracil (5-FU)/folinic acid (FA), in locally-advanced rectal cancer (LARC).</p><p><strong>Methods: </strong>Two cycles of oxaliplatin 130 mg/m(2) plus FA 20 mg/m(2) bolus for 5 days and 5-FU 350 mg/m(2) continuous infusion for 5 days were given during week 1 and 4 of pelvic radiotherapy 46 Gy. Patients with a T3/4 and/or node-positive rectal tumour were eligible. Surgery was performed 4-6 weeks after radiotherapy. The primary endpoint was to determine the rate of pathological response. Secondary endpoints were to assess the rate of clinical response and the safety profile.</p><p><strong>Results: </strong>Between March 2005 and January 2009, a total of 35 patients were enrolled. The pathological down-staging rate was 79% with a pathological complete response rate of 17%. The overall clinical response rate (assessed by computed tomography or transrectal ultrasound) was 77%. Grade 3 diarrhoea and Grade 3 neutropaenia were reported in 14% and 11% of the patients, respectively. Eleven patients did not undergo surgery: four of them refused the operation, and seven patients were inoperable due to disease progression. In 24 patients who had surgery, a sphincter-preserving procedure could be performed in 29%. At the median follow-up time of 28.1 months, 25 patients (71%) survived with no evidence of disease.</p><p><strong>Conclusion: </strong>The promising results in terms of pathological response, and the associated good safety profile of a regimen of oxaliplatin plus 5-FU/FA with concomitant radiotherapy, suggest that the regimen could be used in LARC.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"7 4","pages":"e25"},"PeriodicalIF":0.0,"publicationDate":"2011-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.7.4.e25","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30414646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modified teaching approach for an enhanced medical physics graduate education experience.","authors":"Ib Rutel","doi":"10.2349/biij.7.4.e28","DOIUrl":"https://doi.org/10.2349/biij.7.4.e28","url":null,"abstract":"<p><p>Lecture-based teaching promotes a passive interaction with students. Opportunities to modify this format are available to enhance the overall learning experience for both students and instructors. The description for a discussion-based learning format is presented as it applies to a graduate curriculum with technical (formal mathematical derivation) topics. The presented hybrid method involves several techniques, including problem-based learning, modeling, and online lectures, eliminating didactic lectures. The results from an end-of-course evaluation show that the students appear to prefer the modified format over the more traditional methodology of \"lecture only\" contact time. These results are motivation for further refinement and continued implementation of the described methodology in the current course and potentially other courses within the department graduate curriculum.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"7 4","pages":"e28"},"PeriodicalIF":0.0,"publicationDate":"2011-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2349/biij.7.4.e28","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30414650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pelvic aneurysmal bone cyst.","authors":"Mia Sharifah, H Nurhazla, A Suraya, Sp Tan","doi":"10.2349/biij.7.4.24","DOIUrl":"https://doi.org/10.2349/biij.7.4.24","url":null,"abstract":"<p><p>This paper describes an extremely rare case of a huge aneurysmal bone cyst (ABC) in the pelvis, occurring in the patient's 5(th) decade of life. The patient presented with a history of painless huge pelvic mass for 10 years. Plain radiograph and computed tomography showed huge expansile lytic lesion arising from the right iliac bone. A biopsy was performed and histology confirmed diagnosis of aneurysmal bone cyst. Unfortunately, the patient succumbed to profuse bleeding from the tumour.</p>","PeriodicalId":89331,"journal":{"name":"Biomedical imaging and intervention journal","volume":"7 4","pages":"e24"},"PeriodicalIF":0.0,"publicationDate":"2011-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30415270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}