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Synthesis and antifungal activities of bisbenzazole derivatives 双苯并唑衍生物的合成与抗真菌活性
Bioorganic and Medicinal Chemistry Reports Pub Date : 2024-08-09 DOI: 10.25135/acg.oc.2405.32434
Sule Gursoy, Dilara Ergun, Mehmet Abdullah Alagöz
{"title":"Synthesis and antifungal activities of bisbenzazole derivatives","authors":"Sule Gursoy, Dilara Ergun, Mehmet Abdullah Alagöz","doi":"10.25135/acg.oc.2405.32434","DOIUrl":"https://doi.org/10.25135/acg.oc.2405.32434","url":null,"abstract":"","PeriodicalId":8932,"journal":{"name":"Bioorganic and Medicinal Chemistry Reports","volume":"82 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141922171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of COVID-19 on the thyroid gland in Iraqi females COVID-19 对伊拉克女性甲状腺的影响
Bioorganic and Medicinal Chemistry Reports Pub Date : 2024-02-14 DOI: 10.25135/bmcr.31.23.01.2775
R. Ersan, Kajeen H. Jasim, Noor Adnan Naeem, Lana Ziyad Sulayman, Rayan Sadiq, Nechervan Waheed, Jihan Hasan Jasim, Azheen Qasem
{"title":"Impact of COVID-19 on the thyroid gland in Iraqi females","authors":"R. Ersan, Kajeen H. Jasim, Noor Adnan Naeem, Lana Ziyad Sulayman, Rayan Sadiq, Nechervan Waheed, Jihan Hasan Jasim, Azheen Qasem","doi":"10.25135/bmcr.31.23.01.2775","DOIUrl":"https://doi.org/10.25135/bmcr.31.23.01.2775","url":null,"abstract":"","PeriodicalId":8932,"journal":{"name":"Bioorganic and Medicinal Chemistry Reports","volume":"35 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139777550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of COVID-19 on the thyroid gland in Iraqi females COVID-19 对伊拉克女性甲状腺的影响
Bioorganic and Medicinal Chemistry Reports Pub Date : 2024-02-14 DOI: 10.25135/bmcr.31.23.01.2775
R. Ersan, Kajeen H. Jasim, Noor Adnan Naeem, Lana Ziyad Sulayman, Rayan Sadiq, Nechervan Waheed, Jihan Hasan Jasim, Azheen Qasem
{"title":"Impact of COVID-19 on the thyroid gland in Iraqi females","authors":"R. Ersan, Kajeen H. Jasim, Noor Adnan Naeem, Lana Ziyad Sulayman, Rayan Sadiq, Nechervan Waheed, Jihan Hasan Jasim, Azheen Qasem","doi":"10.25135/bmcr.31.23.01.2775","DOIUrl":"https://doi.org/10.25135/bmcr.31.23.01.2775","url":null,"abstract":"","PeriodicalId":8932,"journal":{"name":"Bioorganic and Medicinal Chemistry Reports","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139837256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fluorinated benzimidazole derivatives: In vitro antimicrobial activity 氟化苯并咪唑衍生物:体外抗菌活性
Bioorganic and Medicinal Chemistry Reports Pub Date : 2023-07-31 DOI: 10.25135/bmcr.30.23.01.2692
Ronak Haj Ersan, Kajeen Jasim, Roaida Sadeeq, Soad Salim, Zina Fadhil, Somaya Mahmood
{"title":"Fluorinated benzimidazole derivatives: In vitro antimicrobial activity","authors":"Ronak Haj Ersan, Kajeen Jasim, Roaida Sadeeq, Soad Salim, Zina Fadhil, Somaya Mahmood","doi":"10.25135/bmcr.30.23.01.2692","DOIUrl":"https://doi.org/10.25135/bmcr.30.23.01.2692","url":null,"abstract":"","PeriodicalId":8932,"journal":{"name":"Bioorganic and Medicinal Chemistry Reports","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135100236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fluorinated benzimidazole derivatives: In vitro antimicrobial activity 氟化苯并咪唑衍生物:体外抗菌活性
Bioorganic and Medicinal Chemistry Reports Pub Date : 2023-04-27 DOI: 10.25135/bmcr.30.23.01.2692x
R. Ersan, Kajeen H. Jasim, Roaida Sadeeq, Soad Salim, Zina Fadhil, Somaya Mahmood
{"title":"Fluorinated benzimidazole derivatives: In vitro antimicrobial activity","authors":"R. Ersan, Kajeen H. Jasim, Roaida Sadeeq, Soad Salim, Zina Fadhil, Somaya Mahmood","doi":"10.25135/bmcr.30.23.01.2692x","DOIUrl":"https://doi.org/10.25135/bmcr.30.23.01.2692x","url":null,"abstract":"","PeriodicalId":8932,"journal":{"name":"Bioorganic and Medicinal Chemistry Reports","volume":"135 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88484768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing machine learning models for acetylcholine esterase inhibitors 比较乙酰胆碱酯酶抑制剂的机器学习模型
Bioorganic and Medicinal Chemistry Reports Pub Date : 2022-08-14 DOI: 10.25135/bmcr.29.22.06.2483
Mehmet Ali Yucel
{"title":"Comparing machine learning models for acetylcholine esterase inhibitors","authors":"Mehmet Ali Yucel","doi":"10.25135/bmcr.29.22.06.2483","DOIUrl":"https://doi.org/10.25135/bmcr.29.22.06.2483","url":null,"abstract":"","PeriodicalId":8932,"journal":{"name":"Bioorganic and Medicinal Chemistry Reports","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86677119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Cytotoxic activity evaluation of naphthalene substituted benzimidazole derivatives 萘取代苯并咪唑衍生物的细胞毒活性评价
Bioorganic and Medicinal Chemistry Reports Pub Date : 2022-05-17 DOI: 10.25135/acg.bmcr..28.2201.2322
R. Ersan, Kajeen H. Jasim, Haytham Sabeeh, K. Ahmed, Darya Abdulsatar, Shan Ali
{"title":"Cytotoxic activity evaluation of naphthalene substituted benzimidazole derivatives","authors":"R. Ersan, Kajeen H. Jasim, Haytham Sabeeh, K. Ahmed, Darya Abdulsatar, Shan Ali","doi":"10.25135/acg.bmcr..28.2201.2322","DOIUrl":"https://doi.org/10.25135/acg.bmcr..28.2201.2322","url":null,"abstract":"","PeriodicalId":8932,"journal":{"name":"Bioorganic and Medicinal Chemistry Reports","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84098132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Determination of Lidocaine HCl in commercially cream and injection forms by GC-FID method GC-FID法测定市售乳膏和注射剂中盐酸利多卡因的含量
Bioorganic and Medicinal Chemistry Reports Pub Date : 2022-05-15 DOI: 10.25135/bmcr.27.2204.2418
Y. Kadioglu, Alptug Atila
{"title":"Determination of Lidocaine HCl in commercially cream and injection forms by GC-FID method","authors":"Y. Kadioglu, Alptug Atila","doi":"10.25135/bmcr.27.2204.2418","DOIUrl":"https://doi.org/10.25135/bmcr.27.2204.2418","url":null,"abstract":"","PeriodicalId":8932,"journal":{"name":"Bioorganic and Medicinal Chemistry Reports","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82314407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuroprotective activity studies of some phenylacetamide derivatives bearing 1H-pyrazole or 1H-1,2,4-triazole 含1h -吡唑或1h -1,2,4-三唑的苯乙酰胺衍生物的神经保护活性研究
Bioorganic and Medicinal Chemistry Reports Pub Date : 2021-11-28 DOI: 10.25135/acg.bmcr.26.2111.2255
Merve Saylam, Ayse H. Tarikogullari, S. Yılmaz, P. Ballar Kirmizibayrak
{"title":"Neuroprotective activity studies of some phenylacetamide derivatives bearing 1H-pyrazole or 1H-1,2,4-triazole","authors":"Merve Saylam, Ayse H. Tarikogullari, S. Yılmaz, P. Ballar Kirmizibayrak","doi":"10.25135/acg.bmcr.26.2111.2255","DOIUrl":"https://doi.org/10.25135/acg.bmcr.26.2111.2255","url":null,"abstract":"","PeriodicalId":8932,"journal":{"name":"Bioorganic and Medicinal Chemistry Reports","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85542306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New molecule design with in-silico methods for Covid-19 treatment 新型分子设计与计算机方法治疗Covid-19
Bioorganic and Medicinal Chemistry Reports Pub Date : 2020-12-12 DOI: 10.25135/acg.bmcr.23.20.08.1773
M. Alagöz
{"title":"New molecule design with in-silico methods for Covid-19 treatment","authors":"M. Alagöz","doi":"10.25135/acg.bmcr.23.20.08.1773","DOIUrl":"https://doi.org/10.25135/acg.bmcr.23.20.08.1773","url":null,"abstract":"Intensive studies are being conducted to develop effective prevention and treatment strategies for the Covid-19 pandemic. During a pandemic, it is vital to act quickly to develop a defense strategy. It usually takes a long time to develop a preventive vaccine, and immediate drug development is needed to reduce the impact of the rapidly increasing Covid-19 pandemic. This study aimed to design an effective and potent drug by selecting remdesivir, a nucleotide analog prodrug that inhibits viral RNA polymerases and is known to be active against Covid-19. Remdesivir is metabolized into active nucleoside triphosphate (NTP) by the host; this metabolite competes with adenosine triphosphate (ATP) for incorporation into the nascent RNA strand. Therefore, molecular docking studies have been conducted based on NTP (the active form of remdesivir), and a target molecule that could be effective against Covid-19 has been designed.","PeriodicalId":8932,"journal":{"name":"Bioorganic and Medicinal Chemistry Reports","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75328352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
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