Arab journal of nephrology and transplantation最新文献_第9页

Scleroderma renal crisis precipitated by steroid treatment in systemic lupus erythematosus and scleroderma overlap syndrome. 系统性红斑狼疮和硬皮病重叠综合征中类固醇治疗引起的硬皮病肾危机。

Arab journal of nephrology and transplantation Pub Date : 2012-01-01 DOI: 10.4314/AJNT.V5I3

A. Alayoud, O. Qamouss, A. Hamzi, M. Benyahia, Z. Oualim

{"title":"Scleroderma renal crisis precipitated by steroid treatment in systemic lupus erythematosus and scleroderma overlap syndrome.","authors":"A. Alayoud, O. Qamouss, A. Hamzi, M. Benyahia, Z. Oualim","doi":"10.4314/AJNT.V5I3","DOIUrl":"https://doi.org/10.4314/AJNT.V5I3","url":null,"abstract":"INTRODUCTION Connective tissue disorders can overlap in various ways. Patients may present with features of more than one specific disease without satisfying the diagnostic criteria and thereafter evolve into a specific disease entity. Occasionally, patients may fulfil simultaneously the diagnostic criteria of two or more diseases. Several cases of systemic sclerosis (SSc) and systemic lupus erythematosus (SLE) overlap syndrome have been reported. SLE patients often develop lupus nephritis, the treatment of which is based on immunosuppression with corticosteroids (CS) and cytotoxic drugs. However, the use of high dose of CS has been associated with scleroderma renal crisis (SRC) in patient with SSc. CASE REPORT a 43-year-old woman presented to the nephrology department of the Military hospital in Rabat, Morocco, in August 2011 with progressive dyspnea and oliguria. She was diagnosed as SLE and scleroderma overlap syndrome based on clinical and serological markers. Renal biopsy showed lupus nephritis. Immunosuppression consisting of high-dose steroid and cyclophosphamide pulses was given. There was response to treatment but 15 days later the course of the disease was complicated by scleroderma renal crisis evidenced by elevated blood pressure, deteriorating kidney function, hemolysis and thrombocytopenia. The patient was treated with perindopril and rapid reduction of steroid doses. This was followed by correction of hemolysis and thrombocytopenia. Two months later, the patient was off dialysis, but had chronic renal insufficiency with an estimated GFR of 25 ml/minute. CONCLUSION This report describes the occurrence of SRC in a patient with lupus nephritis and SSc/ SLE overlap syndrome who was treated by CS and cyclophosphamide.","PeriodicalId":89079,"journal":{"name":"Arab journal of nephrology and transplantation","volume":"5 3 1","pages":"153-7"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70471652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Fatal renal failure due to self administration of Aristolochia Longa after treatment with chemotherapy. 化疗后自行服用马兜铃引起致死性肾衰竭。

Arab journal of nephrology and transplantation Pub Date : 2012-01-01

Illias Tazi, Hatim Nafil, Lahoucine Mahmal

引用次数: 0

Histopathological study of pure primary nephrotic syndrome in adolescents and young Moroccan adults. 摩洛哥青少年和年轻成人纯原发性肾病综合征的组织病理学研究。

Arab journal of nephrology and transplantation Pub Date : 2011-09-01 DOI: 10.4314/ajnt.v4i3.71025

Ghizlane Ayach, Habib El-Filali, Samia Saidi, Salma El-Gharib, Ghizlane Kaobai, Hasna Noaur, Selma El-Khayat, Mohamed Zamed, Ghizlane Medkouri, Khadija Hachim, Mohamed Benghanem, Benyounes Ramdani

{"title":"Histopathological study of pure primary nephrotic syndrome in adolescents and young Moroccan adults.","authors":"Ghizlane Ayach, Habib El-Filali, Samia Saidi, Salma El-Gharib, Ghizlane Kaobai, Hasna Noaur, Selma El-Khayat, Mohamed Zamed, Ghizlane Medkouri, Khadija Hachim, Mohamed Benghanem, Benyounes Ramdani","doi":"10.4314/ajnt.v4i3.71025","DOIUrl":"https://doi.org/10.4314/ajnt.v4i3.71025","url":null,"abstract":"INTRODUCTION\u0000The primary nephrotic syndrome (PNS) is the most common glomerular nephropathy in children. Its diagnosis and management don't require histopathological study. It occurs mainly in the form of minimal glomerular lesion and in most cases respond to corticosteroids. The literature on histological lesions of pure PNS in adolescents and young adults is rare. Thus, there are no criteria or recommendations regarding the indications for renal biopsy in patients aged 12-18 years.\u0000\u0000\u0000METHODS\u0000This is a retrospective study in which we encountered a total of 386 patients aged 12 to 25 years who were admitted and biopsied at the Nephrology Unit of Ibn Roshd Hospital in Casablanca during the period from January 1st, 2000 to September 30th, 2009 . Patients with pure PNS 77 (20%) were included in the study.\u0000\u0000\u0000RESULTS\u0000The average incidence of pure PNS was 7.7 cases per year. The study included 47 males (61%) and 30 females (39%). Patients were sent from all parts of Morocco and the average length of hospital stay was four days. Renal biopsies showed the following morphological lesions: minimal glomerular lesions in 61 cases (79.20%), focal segmental hyalinosis in 7 cases (9.10%), extramembranous glomerulonephritis in 7 cases (9.10%) and 2 cases of renal amyloidosis (2.6%).\u0000\u0000\u0000CONCLUSION\u0000The minimal glomerular lesions were the most common cause of pure primary nephrotic syndrome in patients aged 12-25 years. Initial renal biopsy may not be indicated in this age group, and an empiric therapeutic trial with corticosteroids may be initially considered.","PeriodicalId":89079,"journal":{"name":"Arab journal of nephrology and transplantation","volume":"4 3","pages":"137-40"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4314/ajnt.v4i3.71025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30230311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Undiagnosed hypertension and proteinuria in a market population in Ile-Ife, Nigeria. 尼日利亚Ile-Ife市场人群中未确诊的高血压和蛋白尿

Arab journal of nephrology and transplantation Pub Date : 2011-09-01 DOI: 10.4314/ajnt.v4i3.71026

Arogundade Fatiu, Sanusi Abubakr, Hassan Muzamil, Gbadegesin Aderoju, Olarinoye Funmilayo, Otuyemi Bola, Akinsola Adewale

{"title":"Undiagnosed hypertension and proteinuria in a market population in Ile-Ife, Nigeria.","authors":"Arogundade Fatiu, Sanusi Abubakr, Hassan Muzamil, Gbadegesin Aderoju, Olarinoye Funmilayo, Otuyemi Bola, Akinsola Adewale","doi":"10.4314/ajnt.v4i3.71026","DOIUrl":"https://doi.org/10.4314/ajnt.v4i3.71026","url":null,"abstract":"Introduction: Hypertension and chronic kidney disease (CKD) are common in our urban and rural communities but the majority of affected individuals are not aware of their condition. We conducted free medical examination and screening during one of the market days in Odo-Ogbe market, Ile-Ife, Nigeria to evaluate the magnitude of undiagnosed hypertension and proteinuria.Methods: Participants were taken through a brief medical history and had their socio-demographic data taken. Weight and height were measured and body mass index (BMI) calculated. Blood pressure (BP) was measured using a mercury sphygmomanometer and urinalysis was done with the aid of dipstick test.Results: A total of 286 participants aged 13-90 years (Mean 49.5 ± 15.7 years) were screened. Females constituted 90.2% of the study population. One-hundred and eight (37.7%) of participants had hypertension and only 20 (6.7%) were previously diagnosed. Sixty-nine participants (24.1%) had stage-1 hypertension while 39 (13.6%) had stage-2 hypertension. Fifty-nine percent of participants had BMI above 25 kg/m2. Eighty five participants (29.7%) had proteinuria while only 13 (4.5%) had glycosuria. A significantly higher percentage of participants with stage-1 and stage-2 hypertension had proteinuria compared with non hypertensives. There was a positive correlation between age and BMI (r=0.171, P=0.004), age and systolic BP (r=0.378, P < 0.0001) as well as age and diastolic BP (r=0.197, P=0.001).Conclusion: A high percentage of the studied population (31%) had undiagnosed hypertension and proteinuria (29.7%). Community screening for these disabling non communicable diseases and lifestyle modifications should be encouraged.","PeriodicalId":89079,"journal":{"name":"Arab journal of nephrology and transplantation","volume":"4 3","pages":"141-6"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4314/ajnt.v4i3.71026","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30230802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 25

Systemic lupus erythematosus with severe nephritis that mimicked Henoch-Schoenlein purpura. 系统性红斑狼疮伴严重肾炎，类似过敏性紫癜。

Arab journal of nephrology and transplantation Pub Date : 2011-09-01 DOI: 10.4314/ajnt.v4i3.71029

Ibrahim Al-Attrach, Amar Al-Shibli, Layla Al-Riyami, Suhail Al-Salam

{"title":"Systemic lupus erythematosus with severe nephritis that mimicked Henoch-Schoenlein purpura.","authors":"Ibrahim Al-Attrach, Amar Al-Shibli, Layla Al-Riyami, Suhail Al-Salam","doi":"10.4314/ajnt.v4i3.71029","DOIUrl":"https://doi.org/10.4314/ajnt.v4i3.71029","url":null,"abstract":"Introduction: Systemic lupus erythematosus (SLE) belongs to a family of related autoimmune rheumatic disorders that are capable of affecting multiple organs, and they are all associated with a variety of autoantibodies. Henoch Schoenlein purpura (HSP) is a sort of systemic vasculitis that is not associated with auto-antibodies and can affect different organs including the kidneys.Case report: A 12 year-old girl presented with abdominal pain, low grade fever, swollen and tender feet and left hand, skin rash on the lower extremities, and high blood pressure. Initial laboratory tests revealed severe proteinuria, microscopic hematuria and low C3 level. Renal biopsy showed diffuse proliferative glomerulonephritis with IgA, fibrinogen and C3 deposits. The case was accordingly diagnosed as HSP with severe IgA nephropathy. Treatment was started with mycophenolate mofetil (MMF) and pulse methylprednisolone followed by prednisolone. The patient improved and treatment was discontinued after 5.5 months. One month after withdrawal of her medications, the patient presented again with serositis and recurrent proteinuria. Both antinuclear antibodies (ANA) and anti dsDNA were positive. At this point she was diagnosed to have SLE disease and immunosuppressive treatment was restarted. Following this, symptoms disappeared, proteinuria regressed and anti-dsDNA titer dropped.Conclusion: This case presented with features of HSP and was later-on diagnosed to have SLE. This kind of clinical overlapping has not been reported in the literature to the best of our knowledge.","PeriodicalId":89079,"journal":{"name":"Arab journal of nephrology and transplantation","volume":"4 3","pages":"159-61"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4314/ajnt.v4i3.71029","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30230805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Hepatic lymphomas post renal transplantation may signify worse disease behavior: analysis of data from 26 international studies. 肾移植后肝淋巴瘤可能意味着更糟糕的疾病行为:来自26项国际研究的数据分析

Arab journal of nephrology and transplantation Pub Date : 2011-09-01 DOI: 10.4314/ajnt.v4i3.71022

Hossein Khedmat, Saeed Taheri

{"title":"Hepatic lymphomas post renal transplantation may signify worse disease behavior: analysis of data from 26 international studies.","authors":"Hossein Khedmat, Saeed Taheri","doi":"10.4314/ajnt.v4i3.71022","DOIUrl":"https://doi.org/10.4314/ajnt.v4i3.71022","url":null,"abstract":"Introduction: Hepatic involvement by posttransplant lymphoproliferative disorders (PTLD) is an important but rarely investigated issue. In the current study, we aimed to pool data of cases of PTLD localization in liver (L-PTLD) among renal allograft recipients from different series to find new perspectives on the disease.Methods: We conducted a comprehensive search for the available data through PubMed and Google Scholar for reports of PTLD localization in the liver and surrounding lymph nodes in renal allograft recipients. Data of 232 cases from 26 international studies have been pooled and reanalyzed.Results: Patients with L-PTLD were significantly more likely to be of male gender (P=0.02). Death due to PTLD was higher in L-PTLD patients (P=0.06). Disseminated PTLD, based on our definition, was significantly more prevalent in L-PTLD than in none-liver-PTLD (NL-PTLD) (P < 0.001); the same finding was noted with multi-organ involvement which was significantly higher in L-PTLD (P<0.001). L-PTLD was significantly more likely to complicate heart (P=0.03), bone marrow (P=0.002), spleen (P=0.01), and kidney allograft Involvement (P=0.04).Conclusion: We conclude that renal transplant patients exhibiting liver localization for PTLD should be carefully followed for multi-organ involvement. Most notably, bone marrow biopsy should be considered, and evaluations for renal allograft, heart and spleen localization for PTLD should be executed. Due to the unfavorable characters of liver localization by PTLD in renal recipients, we propose higher levels of evaluations and follow up for these patients. Prospective studies with larger patient populations are needed to confirm our results.","PeriodicalId":89079,"journal":{"name":"Arab journal of nephrology and transplantation","volume":"4 3","pages":"109-16"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4314/ajnt.v4i3.71022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30230307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Serum leptin and bone mineral density in hemodialysis patients with or without liver diseases. 有或无肝脏疾病的血液透析患者血清瘦素和骨密度。

Arab journal of nephrology and transplantation Pub Date : 2011-09-01 DOI: 10.4314/ajnt.v4i3.71030

Tarek A Ghonemy, Ebrahim M Salim, Marwan Atia, Ahmed Fekry, Khalid Shawky

{"title":"Serum leptin and bone mineral density in hemodialysis patients with or without liver diseases.","authors":"Tarek A Ghonemy, Ebrahim M Salim, Marwan Atia, Ahmed Fekry, Khalid Shawky","doi":"10.4314/ajnt.v4i3.71030","DOIUrl":"https://doi.org/10.4314/ajnt.v4i3.71030","url":null,"abstract":"Introduction: Leptin is a hormone secreted by adipocytes that plays an important role in regulating appetite and energy expenditure. Our aim was to evaluate serum leptin level in hemodialysis (HD) patients with or without chronic liver disease (CLD) and study the relationship between serum leptin level and bone mineral density in these groups of patients.Methods: we recruited 20 healthy volunteers as controls (group I), 20 patients on regular HD with normal liver function (group II), 20 CLD patients with normal kidney function (group III) and 20 patients on regular HD with CLD (group IV). We measured serum calcium, phosphorus, parathyroid hormone (PTH), total alkaline phosphatase (ALP), serum leptin, 24-hours urinary hydroxyproline and bone mineral density (BMD) of the lumber spine and femoral neck by DEXA scan.Results: Serum leptin level was significantly higher (p < 0.001) in HD patients and CLD patients compared to controls. Its level was also significantly elevated in HD patients without liver disease (group II) compared to patients with CLD who had no renal failure (group III). Urinary hydroxyproline level was increased in both HD patients and CLD patients. We detected a positive correlation between serum leptin level and urinary hydroxyproline in all patient groups. There was a significant decrease in BMD in HD and CLD patients. BMD was significantly lower in HD patients without CLD compared to HD patients with CLD. There was a significant negative correlation between serum leptin level and BMD in CLD patients without renal disease but not in other groups (r = - 0.6, P = 0.01).Conclusion: Serum leptin is elevated in HD patients with or without liver disease and in CLD patients. Serum leptin level is inversely correlated with BMD in CLD patients without renal disease.","PeriodicalId":89079,"journal":{"name":"Arab journal of nephrology and transplantation","volume":"4 3","pages":"131-6"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4314/ajnt.v4i3.71030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30230310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Chemokine and chemokine receptor gene polymorphism in Tunisian hemodialysis patients with HCV infection. 突尼斯血液透析患者HCV感染的趋化因子和趋化因子受体基因多态性。

Arab journal of nephrology and transplantation Pub Date : 2011-09-01 DOI: 10.4314/ajnt.v4i3.71023

Leila Ksiaa Cheikh Rouhou, Yousr Lakhoua Gorgi, Hajer Aounallah Skhiri, Houda Aouadi, Salwa Jendoubi Ayed, Imen Sfar, Khaled Ayed, Taieb Ben Abdallah

{"title":"Chemokine and chemokine receptor gene polymorphism in Tunisian hemodialysis patients with HCV infection.","authors":"Leila Ksiaa Cheikh Rouhou, Yousr Lakhoua Gorgi, Hajer Aounallah Skhiri, Houda Aouadi, Salwa Jendoubi Ayed, Imen Sfar, Khaled Ayed, Taieb Ben Abdallah","doi":"10.4314/ajnt.v4i3.71023","DOIUrl":"https://doi.org/10.4314/ajnt.v4i3.71023","url":null,"abstract":"Introduction: Our aim was to investigate the possibility of a significant relationship between chemokines and chemokine receptor genes polymorphisms and the spontaneous clearance or the persistence of HCV infection.Methods: A total of 96 hemodialysis (HD) patients infected with HCV were classified into two groups: G1 included 73 patients with persistently positive HCV-RNA and G2 included 23 HD patients who have spontaneously eliminated the virus. The control group consisted of 170 healthy blood donors. All subjects were genotyped for CCR5 ?32, CCR5 (-59029) A/G, CCR2 (64Ile) and MCP-1(-2518) A/G gene polymorphisms.Results: Our results showed a statistically significant increased frequencies of the CCR2 (64Ile) and the (-59029) CCR5 A alleles in patients infected with HCV (22.1% and 35.9%) compared to G1 (24.3% and 40.6%) and compared to controls (14.4% and 20%). We also observed a lower frequency of the MCP-1 G allele and a greater frequency of the CCR5?32 variant in G2 (15.2% and 6.5%) compared to G1 (22.6% and 1.4%) that was not statistically significant. However, adjustment for known covariates (age, gender and HCV genotypes) didn't confirm the results of univariate analysis.Conclusion: In conclusion, our study suggests a possible role for some of the studied chemokines polymorphisms in the spontaneous clearance or persistence of HCV infection in Tunisian population. These results should be further investigated by a prospective cohort studies and large population-based studies.","PeriodicalId":89079,"journal":{"name":"Arab journal of nephrology and transplantation","volume":"4 3","pages":"117-24"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4314/ajnt.v4i3.71023","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30230308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

A study of quality of life and its determinants among hemodialysis patients using the KDQOL-SF instrument in one center in Saudi Arabia. 沙特阿拉伯某中心使用KDQOL-SF仪器对血液透析患者生活质量及其决定因素的研究

Arab journal of nephrology and transplantation Pub Date : 2011-09-01 DOI: 10.4314/ajnt.v4i3.71024

Ahmed AL-Jumaih, Kamel Al-Onazi, Salih Binsalih, Fayez Hejaili, Abdulla Al-Sayyari

{"title":"A study of quality of life and its determinants among hemodialysis patients using the KDQOL-SF instrument in one center in Saudi Arabia.","authors":"Ahmed AL-Jumaih, Kamel Al-Onazi, Salih Binsalih, Fayez Hejaili, Abdulla Al-Sayyari","doi":"10.4314/ajnt.v4i3.71024","DOIUrl":"https://doi.org/10.4314/ajnt.v4i3.71024","url":null,"abstract":"Introduction: We aimed to assess quality of life (QOL) among Saudi hemodialysis (HD) patients and the impact on the QOL of a certain demographic and clinical factors.Methods: The QOL was assessed using an Arabic version of Kidney Disease Quality of Life Instrument Short Form (KDQOL-SF). Mean scores were compared for individual domain scores and for the three composite summary scores, namely the mental component score (MCS), the physical component score (PCS) and kidney-disease component score (KDCS).Results: The study included one hundred chronic HD patients from King Abdulaziz Medical City, Riyadh. The overall mean score was 60.4. Domains with very low scores were \"cognitive function\", \"role-emotional\", \"role-physical\" and \"work status\". Domains with high scores were \"patient satisfaction\", \"dialysis staff encouragement\" and \"quality of social interaction\". The mean scores for \"KDCS\", \"MCS\" and \"PCS\" were 59.7, 54.2 and 52.7 respectively. KDC scores were higher among males and the married group. PCS scores were higher among males, patients aged < 40 years, and the higher income group. MCS scores were higher among males and the higher income groups. There was a positive correlation between \"KDCS\" and \"MCS\"(r=0.62, P=0.0001); and between \"KDCS\" and \"PCS\" (r=0.65, P=0.0001).Conclusion: The current study provides a detailed description of the QOL scores of a group of Saudi HD patients and the impact of certain factors on their QOL. Low scores were seen in the \"work status\", \"cognitive function\", \"role-physical\" and \"role-emotional\" while high scores were seen in \"patient satisfaction\", \"dialysis staff encouragement\" and \"quality of social interaction\" domains.","PeriodicalId":89079,"journal":{"name":"Arab journal of nephrology and transplantation","volume":"4 3","pages":"125-30"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4314/ajnt.v4i3.71024","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30230309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 59

High ureteric injury following multiorgan recovery: successful kidney transplant with Boari flap ureterocystostomy reconstruction. 多器官恢复后高位输尿管损伤:成功肾移植伴Boari皮瓣输尿管膀胱造口重建。

Arab journal of nephrology and transplantation Pub Date : 2011-09-01 DOI: 10.4314/ajnt.v4i3.71028

Michael Charlesworth, Gabriele Marangoni, Niaz Ahmad

{"title":"High ureteric injury following multiorgan recovery: successful kidney transplant with Boari flap ureterocystostomy reconstruction.","authors":"Michael Charlesworth, Gabriele Marangoni, Niaz Ahmad","doi":"10.4314/ajnt.v4i3.71028","DOIUrl":"https://doi.org/10.4314/ajnt.v4i3.71028","url":null,"abstract":"Introduction: Despite increased utilization of marginal organs, there is still a marked disparity between organ supply and demand for transplantation. To maximize resources, it is imperative that procured organs are in good condition. Surgical damage at organ recovery can happen and organs are sometimes discarded as a result. We describe a damaged recovered kidney with high ureteric transection that was successfully transplanted using a primary Boari flap ureterocystostomy.Case report: The donor kidney was procured form a deceased donor and sustained damage by transection of the ureter just distal to the pelvi-ureteric junction at organ recovery. The recipient had been on the transplant waiting list for eight years and not accepting this kidney would have seriously jeopardized her chance of future transplantation. Several centers rejected the donor kidney. We assessed the kidney and decided to proceed with transplantation. The kidney was successfully transplanted. A primary Boari flap was constructed and the transplant ureter implanted onto the bladder. The post-operative course was complicated by urine leak that settled down after management by nephrostomy insertion and bladder catheterization. The patient made a good recovery and remained well at six monthly follow up with a serum creatinine of 1.7 mg/dl.Conclusion: Primary Boari flap ureterocystostomy is a viable option when the transplant surgeon is faced with a high ureteric injury in the procured kidney. Since most patients wait years for a suitable graft and some may never find an adequate match, every effort should be made to effectively utilize the scarce available resources to the fullest.","PeriodicalId":89079,"journal":{"name":"Arab journal of nephrology and transplantation","volume":"4 3","pages":"155-8"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4314/ajnt.v4i3.71028","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30230804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6