{"title":"Food Composition and Acid-Base Balance: Alimentary Acid Load and Clinical Implications in Neonates","authors":"H. Kalhoff, F. Manz, P. Kiwull, H. Kiwull-Schöne","doi":"10.2174/1874288200802010005","DOIUrl":"https://doi.org/10.2174/1874288200802010005","url":null,"abstract":"In preterm neonates, functional limits of pulmonary and/or renal regulation processes and the considerable acid load of common formulas predispose to a great risk for the development of latent metabolic acidosis, characterized by e.g. impaired mineralization and reduced growth. Furthermore, in a prospective study in very low birth weight-infants, latent metabolic acidosis was assumed to contribute to the development of nephrocalcinosis. To obtain fundamental data of acid- base regulation in preterm infants under different diets, we investigated 48 preterm infants fed their own mothers milk (28 native human milk, 20 enriched with fortifier) and 34 patients on formula (23 on a standard batch, 11 on a modified batch with reduced acid load). Irrespective of the diet, we could not find notable differences between individual data of acid-base status in blood samples. In contrast, dietary acid-base intake was accurately reflected in the urine, pointing to ef- fective individual compensation of alimentary acid-load by renal base saving mechanisms. Thus, in preterm infants, nutri- tional acid-base challenges can be judged earlier and more safely by urinary than by blood acid-base analysis A physio- logically based and empirically adjusted calculation model allows to estimate the impact of mineral and protein content of a formula on the urinary ionogram and thus on the average renal net acid excretion in a regularly fed and growing preterm infant. The algorithm of this proposed calculation model could prove to be a useful tool in the design of new formulas with adaequate base supply for preterm infants.","PeriodicalId":89036,"journal":{"name":"The open nutrition journal","volume":"58 1","pages":"5-8"},"PeriodicalIF":0.0,"publicationDate":"2008-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80151677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Validity and Reproducibility of a Semi-Quantitative Food Frequency Questionnaire Adapted to an Israeli Population","authors":"D. Itzhaki, H. Rennert, G. Rozen, G. Rennert","doi":"10.2174/1874288200802010009","DOIUrl":"https://doi.org/10.2174/1874288200802010009","url":null,"abstract":"Assessment of individual representative dietary practices in epidemiologic research has long been a challenge. Given the differences in eating habits and availability of foods between populations, a study was set to test the reproduci- bility and validity of an Israeli-adapted semi-quantitative food frequency questionnaire (SFFQ) used in case-control stud- ies of cancer etiology. Two hundred volunteers between the ages 22-60 were randomly assigned to either complete an SFFQ independently or by nutritionist interview. Participants were then asked to fill out a 3-day food record (FR). SSFQ was repeated 3 months later. Reliability of the repeated SSFQ was examined using Pearson correlations; paired t-tests and Mann-Whitney Rank Test were used to measure reliability and validity of the SFFQ. Overall, there was >85% agreement ± 1 category between the two encounters in over 75% of the food items. Percent of calories from proteins, fats and carbohydrates were similar for both self-administered and interviewed groups. The major- ity of correlations between the 1 st and 2 nd SSFQs for the micronutrients were above 0.75. No differences were noted in percent energy from proteins, fats or carbohydrates between self-administered and interviewer-assisted SSFQ and FR. The Israeli FFQ was found in our study to be highly reproducible and valid compared to a dietary record.","PeriodicalId":89036,"journal":{"name":"The open nutrition journal","volume":"355 1","pages":"9-14"},"PeriodicalIF":0.0,"publicationDate":"2008-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82617937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Current Dietary Pattern In Central Italy","authors":"E. Matteucci, O. Giampietro","doi":"10.2174/1874288200802010015","DOIUrl":"https://doi.org/10.2174/1874288200802010015","url":null,"abstract":"Nutrition is considered to be one of the key components in the development of most chronic degenerative dis- eases so that medical nutrition therapy has become important in their primary prevention. Food-based dietary guidelines provide the following values: the Lowest Threshold Intake (LTI), the Average Requirement (AR) and the Population Ref- erence Intake (PRI) or Recommended Dietary Allowance (RDA). RDA indicates the quantity of a nutrient that must be present in the food supply if the dietary requirements of most of the population are to be met. Contrary to the established optimistic belief about Mediterranean diet, we have repeatedly documented widespread unhealthy dietary behaviours in adult subjects living in Pisa. The distribution of energy sources was incorrect and fibre consumption did not match general guidelines. Moreover, mild to moderate combined element (calcium) and vitamin (vitamin B1, folates, vitamin D, and vi- tamin E) deficient intakes were observed. The finding of essential nutrient deficiencies in otherwise over-nourished adults prompted us to reconsider the variety and abundance of foods required to guarantee the reference requirements for those substances and which are the historical, environmental, and contingent factors able to prevent the adequacy of food sup- plies in meeting physiological needs.","PeriodicalId":89036,"journal":{"name":"The open nutrition journal","volume":"416 1","pages":"15-22"},"PeriodicalIF":0.0,"publicationDate":"2008-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80104167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acid Base Considerations in Stone-Age Farming Sweet Potato Eaters, Modern-Day Sweet Potato Eaters, and High-Protein Consumers","authors":"T. Remer, S. Berkemeyer, F. Manz","doi":"10.2174/1874288200802010023","DOIUrl":"https://doi.org/10.2174/1874288200802010023","url":null,"abstract":"Net endogenous acid production (NEAP) can be estimated by a primarily anthropometry-dependent organic acid anion (OA) component and the particularly diet-dependent potential renal acid load (PRAL). However, there is evi- dence that certain foods may also impact on the OA component. Here, we discuss measurements of urinary 24-h OA ex- cretion obtained in healthy subjects, against the background of relevant literature with a special focus on former Papuan New Guinea stone-age farmers eating predominantly highland sweet potatoes. Contrary to the reports in Papuans, we ob- served only modest increases of 5-12% in 24-h excretion rates of OAs (including the detoxification product of phenolic and benzoic acids, i.e., hippuric acid) in healthy adults consuming commonly available yellow-fleshed sweet potatoes. This and additional results on OA increases after higher protein intakes suggest that a specification of the NEAP=PRAL+OA model for estimating the diet-dependent acid load to the metabolic system might be useful regarding particular foods and their effects on the OA component.","PeriodicalId":89036,"journal":{"name":"The open nutrition journal","volume":"10 1","pages":"23-28"},"PeriodicalIF":0.0,"publicationDate":"2008-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84977564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contribution of Various Dietary Constituents to the Acid Base Status: Interest of Animal Models of Latent Metabolic Acidosis","authors":"C. Demigné, H. Sabboh, M. Horcajada, V. Coxam","doi":"10.2174/1874288200802010001","DOIUrl":"https://doi.org/10.2174/1874288200802010001","url":null,"abstract":"Animal models of metabolic acidosis are generally based on drastic treatments and are poorly suitable as mod- els of latent metabolic acidosis (LMA). Specific rodent diets have been evaluated as LMA models, together with their re- sponsiveness to dietary alkalinizing factors. Using this model, the possibility to obtain LMA states with moderate levels of protein intake was identified, pointing to the critical role of anions in the mineral moiety of the diet. The potential role of large intestine fermentations to acid-base control has also been examined with this model.","PeriodicalId":89036,"journal":{"name":"The open nutrition journal","volume":"6 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2008-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88703030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Variations in the Glycemic Response to Carbohydrates: Do High Responders Have a Special Benefit of Using Low Glycemic Foods?","authors":"A. Høstmark","doi":"10.2174/1874288200701010001","DOIUrl":"https://doi.org/10.2174/1874288200701010001","url":null,"abstract":"The postprandial blood glucose elevation (PPG) seems to be an important risk factor for diabetes Type 2 and coronary heart disease. We have tested whether high responders have a greater PPG reduction than low responders when changing from high to low glycemic foods, as might be anticipated. In 25 healthy, young men the glycemic effects of six different, low glycemic foods (each ingested in portions providing 50 g carbohydrates) were determined and compared with the glycemic response after intake of 50 g glucose. The reduction in glycemia (delta incremental area under the curve) was proportional to the glycemic response after ingesting glucose (r > 0.8; p<0,001). Thus, high responders to in- gested glucose might have a special benefit of using low glycemic foods. The standard deviations of the GI and GL are high, pre- sumably due to great inter- individual variations. It might be suggested that the reduction in the glycemic effect after in- gesting a low glycemic food might be related to the subject's maximal glycemic response, as expressed either in absolute or relative terms. Accordingly, in the present work we ask the question: Is there a relationship between the IAUC val- ues after ingesting pure glucose and the reductions in IAUC (delta IAUC) observed after ingesting different low glycemic foods containing the same amount of carbohydrate? The re- ductions in glycemic effect were expressed in relative and absolute terms.","PeriodicalId":89036,"journal":{"name":"The open nutrition journal","volume":"4 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2007-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79538826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sai Krupa Das, Cheryl H Gilhooly, Julie K Golden, Anastassios G Pittas, Paul J Fuss, Gerard E Dallal, Megan A McCrory, Edward Saltzman, Susan B Roberts
{"title":"Long Term Effects of Energy-Restricted Diets Differing in Glycemic Load on Metabolic Adaptation and Body Composition.","authors":"Sai Krupa Das, Cheryl H Gilhooly, Julie K Golden, Anastassios G Pittas, Paul J Fuss, Gerard E Dallal, Megan A McCrory, Edward Saltzman, Susan B Roberts","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A randomized controlled trial of high glycemic load (HG) and low glycemic load (LG) diets with food provided for 6 months and self-administered for 6 additional months at 30% caloric restriction (CR) was performed in 29 overweight adults (mean+/-SD, age 35+/-5y; BMI 27.5+/-1.5 kg/m(2)). Total energy expenditure (TEE), resting metabolic rate (RMR), fat and fat free mass (FFM), were measured at 3, 6 and 12 months. Changes in TEE, but not changes in RMR, were greater than accounted for by the loss of FFM and fat mass (P=0.001-0.013) suggesting an adaptive response to long-term CR. There was no significant effect of diet group on change in RMR or TEE. However, in subjects who lost >5% body weight (n=26), the LG diet group had a higher percentage of weight loss as fat than the HG group (p<0.05), a finding that may have implications for dietary recommendations during weight reduction.</p>","PeriodicalId":89036,"journal":{"name":"The open nutrition journal","volume":"85 4","pages":"1023-1030"},"PeriodicalIF":0.0,"publicationDate":"2007-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920502/pdf/nihms187853.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29187947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}