Soo Jung Kang, Jihyun Ha, Seo Jung Hwang, Hyo Jin Kim
{"title":"Long Term Outcomes of Left Atrial Reservoir Function in Children with a History of Kawasaki Disease.","authors":"Soo Jung Kang, Jihyun Ha, Seo Jung Hwang, Hyo Jin Kim","doi":"10.4250/jcu.2018.26.1.26","DOIUrl":"https://doi.org/10.4250/jcu.2018.26.1.26","url":null,"abstract":"<p><strong>Background: </strong>Decreased left atrial (LA) reservoir function is reported to be associated with elevated left ventricular (LV) end diastolic pressure and LV diastolic dysfunction. Echocardiographic parameters that reflect LA reservoir function include LA total emptying fraction [(maximum LA volume - minimum LA volume) / maximum LA volume], peak LA longitudinal strain (PLALS) at systole, and LA stiffness index (E/E´/PLALS). We aimed to investigate the long-term outcomes of LV diastolic function in children with a history of Kawasaki disease (KD) (KDHx group) by assessing LA reservoir function.</p><p><strong>Methods: </strong>Retrospectively, echocardiograms performed at a mean follow-up period of 5 years after the acute phase of KD in 24 children in the KDHx group were compared to those from 20 normal control subjects. LA total emptying fraction, PLALS, LA stiffness index, LV peak longitudinal systolic strain (ε), and strain rate (SR) were evaluated with conventional echocardiographic parameters.</p><p><strong>Results: </strong>The mean age at long term follow-up echocardiography in children in the KDHx group was 6.8 years. Five children (20.8%) had coronary artery lesions (CALs) in the acute stage of KD. No children showed CALs at a mean follow-up period of 5 years after the acute phase of KD. There were no significant differences in the conventional echocardiographic parameters and in LA total emptying fraction, PLALS, LA stiffness index, LV peak longitudinal systolic ε, and SR, between the children in the KDHx and control group.</p><p><strong>Conclusion: </strong>LV diastolic function assessed by LA reservoir function parameters at long-term follow-up in children in the KDHx group appears to be favorable.</p>","PeriodicalId":88913,"journal":{"name":"Journal of cardiovascular ultrasound","volume":"26 1","pages":"26-32"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4250/jcu.2018.26.1.26","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35985988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyungseop Kim, Woo-Baek Chung, Kyoung Im Cho, Bong-Joon Kim, Jeong-Sook Seo, Seong-Mi Park, Hak Jin Kim, Ju-Hee Lee, Eun Kyoung Kim, Ho-Joong Youn
{"title":"Diagnosis, Treatment, and Prevention of Cardiovascular Toxicity Related to Anti-Cancer Treatment in Clinical Practice: An Opinion Paper from the Working Group on Cardio-Oncology of the Korean Society of Echocardiography.","authors":"Hyungseop Kim, Woo-Baek Chung, Kyoung Im Cho, Bong-Joon Kim, Jeong-Sook Seo, Seong-Mi Park, Hak Jin Kim, Ju-Hee Lee, Eun Kyoung Kim, Ho-Joong Youn","doi":"10.4250/jcu.2018.26.1.1","DOIUrl":"10.4250/jcu.2018.26.1.1","url":null,"abstract":"<p><p>Cardiovascular (CV) toxicity associated with anti-cancer treatment is commonly encountered and raises critical problems that often result in serious morbidity or mortality. Most cardiac toxicities are related to the cumulative dose of chemotherapy; however, the type of chemotherapy, concomitant agents, and/or conventional CV risk factors have been frequently implicated in CV toxicity. Approximately half of the patients exhibiting CV toxicity receive an anthracycline-based regimen. Therefore, serologic biomarkers or cardiac imagings are important during anti-cancer treatment for early detection and the decision of appropriate management of cardiotoxicity. However, given the difficulty in determining a causal relationship, a multidisciplinary collaborative approach between cardiologists and oncologists is required. In this review, we summarize the CV toxicity and focus on the role of cardiac imaging in management strategies for cardiotoxicity associated with anti-cancer treatment.</p>","PeriodicalId":88913,"journal":{"name":"Journal of cardiovascular ultrasound","volume":"26 1","pages":"1-25"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d2/81/jcu-26-1.PMC5881080.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35985989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Soo Jung Kang, Young Sun Cho, Seo Jung Hwang, Hyo Jin Kim
{"title":"Outcomes of Left Ventricular Function According to Treatment Response for a Patent Ductus Arteriosus in Preterm Infants.","authors":"Soo Jung Kang, Young Sun Cho, Seo Jung Hwang, Hyo Jin Kim","doi":"10.4250/jcu.2017.25.4.131","DOIUrl":"https://doi.org/10.4250/jcu.2017.25.4.131","url":null,"abstract":"<p><strong>Background: </strong>To evaluate the outcomes of left ventricular (LV) function according to treatment response for a hemodynamically significant patent ductus arteriosus (hsPDA) in preterm infants.</p><p><strong>Methods: </strong>Echocardiograms of 21 preterm infants born at gestational age < 31 weeks obtained at term-equivalent age were retrospectively studied. Among preterm infants with a hsPDA, 9 underwent ligation after failure of pharmacological closure (ligation group) and 6 experienced successful pharmacological closure (medication group). Six preterm infants without hsPDA (no-hsPDA group) were studied as controls. LV peak longitudinal systolic strain (ε) of each infant was retrospectively obtained from echocardiograms using velocity vector imaging, along with neonatal outcomes.</p><p><strong>Results: </strong>Pharmacological closures were attempted at postnatal day 2-3. In the ligation group, the median postnatal age at ligation was 20 days. In the ligation group, LV peak longitudinal systolic ε was significantly decreased at term-equivalent age compared to the other groups. Between the medication and no-hsPDA groups, LV peak longitudinal systolic ε did not differ significantly. Among the neonatal outcomes, infants who experienced necrotizing enterocolitis (NEC) showed significantly decreased LV peak longitudinal systolic ε compared to the infants who did not experience NEC .</p><p><strong>Conclusion: </strong>We speculate that in preterm infants with an hsPDA, in cases of medical treatment failure, early PDA ligation at less than 20 days of postnatal age would be beneficial for preserving LV systolic function.</p>","PeriodicalId":88913,"journal":{"name":"Journal of cardiovascular ultrasound","volume":"25 4","pages":"131-137"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4250/jcu.2017.25.4.131","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35736693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Mindfulness Based Stress Reduction Therapy on Myocardial Function and Endothelial Dysfunction in Female Patients with Microvascular Angina.","authors":"Bong Joon Kim, In Suk Cho, Kyoung Im Cho","doi":"10.4250/jcu.2017.25.4.118","DOIUrl":"https://doi.org/10.4250/jcu.2017.25.4.118","url":null,"abstract":"<p><strong>Background: </strong>Mindfulness-based stress reduction (MBSR) is a structured group program that employs mindfulness meditation to alleviate suffering associated with physical, psychosomatic, and psychiatric disorders. In this study, we investigate the impact of MBSR on left ventricular (LV) and endothelial function in female patients with microvascular angina.</p><p><strong>Methods: </strong>A total of 34 female patients (mean age 52.2 ± 13.8 years) diagnosed with microvascular angina underwent a MBSR program with anti-anginal medication for 8 weeks. The global longitudinal strain (GLS) of the LV was used as a parameter to assess myocardial function and reactive brachial flow-mediated dilatation (FMD) was used to assess endothelial function. Symptoms were analyzed by the Symptom Checklist 90 Revised to determine emotional stress. Changes in GLS and FMD between baseline and post-MBSR were analyzed.</p><p><strong>Results: </strong>After 8 weeks of programmed MBSR treatment, stress parameters were significantly decreased. In addition, GLS (-19.5 ± 2.1% vs. -16.6 ± 2.5%, <i>p</i> < 0.001) and reactive FMD significantly improved (8.9 ± 3.0% vs. 6.9 ± 2.6%, <i>p</i> = 0.005) after MBSR compared to baseline. The changes in GLS correlated to changes in FMD (r = 0.120, <i>p</i> = 0.340) and with the changes in most stress parameters.</p><p><strong>Conclusion: </strong>MBSR has beneficial impacts on myocardial and endothelial function in female patients with microvascular angina.</p>","PeriodicalId":88913,"journal":{"name":"Journal of cardiovascular ultrasound","volume":"25 4","pages":"118-123"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4250/jcu.2017.25.4.118","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35736784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyung Yoon Kim, Joon-Hyung Doh, Shin Yi Jang, Eun Kyoung Kim, Joo-Yong Hahn, Duk-Kyung Kim
{"title":"Gender Differences in Clinical Profiles of Stress-Induced Cardiomyopathy.","authors":"Hyung Yoon Kim, Joon-Hyung Doh, Shin Yi Jang, Eun Kyoung Kim, Joo-Yong Hahn, Duk-Kyung Kim","doi":"10.4250/jcu.2017.25.4.111","DOIUrl":"https://doi.org/10.4250/jcu.2017.25.4.111","url":null,"abstract":"<p><strong>Background: </strong>Although stress-induced cardiomyopathy (SCMP) is reported to be more common in women, little is known about gender differences in patients with SCMP. The aim of the study was to describe clinical features of patients with SCMP according to gender.</p><p><strong>Methods: </strong>One hundred and three patients diagnosed with definite SCMP at a single tertiary institute from January 1997 to August 2014 were enrolled. SCMP was more common in women than in men.</p><p><strong>Results: </strong>Age at presentation was not significantly different between the two groups (<i>p</i> = 0.758). Preceding physical stress, especially acute medical illness, was more common in male patients (<i>p</i> = 0.014), whereas emotional stress was more common in female patients (<i>p</i> = 0.016). Severity of medical illness classified by the Acute Physiology and Chronic Health Evaluation (APACHE) II score at the time of SCMP diagnosis was not significantly different between men and women (<i>p</i> = 0.752). Clinical characteristics, including symptoms, laboratory and electrocardiographic findings, were similar. However, pump failure was more severe in men (<i>p</i> = 0.024). Clinical outcomes were not statistically different (<i>p</i> = 0.220). Preceding physical stress and lower left ventricular systolic function after 2 months were independent risk factors for all-cause mortality for both genders. Women with an APACHE II score ≥ 15 and men with reduced left ventricular ejection fraction after 2 months had a greater risk of poor prognosis.</p><p><strong>Conclusion: </strong>SCMP was more common in female patients. Female patients more commonly experienced preceding emotional stress, whereas physical stress was more common in male patients. Systolic dysfunction was more severe in men. Long-term clinical outcomes appeared to be similar between men and women.</p>","PeriodicalId":88913,"journal":{"name":"Journal of cardiovascular ultrasound","volume":"25 4","pages":"111-117"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4250/jcu.2017.25.4.111","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35736782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ju-Hee Lee, Jae-Hyeong Park, Seung Woo Park, Woo-Shik Kim, Il Suk Sohn, Jung Yeon Chin, Jung Sun Cho, Ho-Joong Youn, Hae Ok Jung, Sun Hwa Lee, Seong-Hwan Kim, Wook-Jin Chung, Chi Young Shim, Jin-Won Jeong, Eui-Young Choi, Se-Joong Rim, Jang-Young Kim, Kye Hun Kim, Joon-Han Shin, Dae-Hee Kim, Ung Jeon, Jung Hyun Choi, Yong-Jin Kim, Seung Jae Joo, Ki-Hong Kim, Kyoung Im Cho, Goo-Yeong Cho
{"title":"Current Awareness and Use of the Strain Echocardiography in Routine Clinical Practices: Result of a Nationwide Survey in Korea.","authors":"Ju-Hee Lee, Jae-Hyeong Park, Seung Woo Park, Woo-Shik Kim, Il Suk Sohn, Jung Yeon Chin, Jung Sun Cho, Ho-Joong Youn, Hae Ok Jung, Sun Hwa Lee, Seong-Hwan Kim, Wook-Jin Chung, Chi Young Shim, Jin-Won Jeong, Eui-Young Choi, Se-Joong Rim, Jang-Young Kim, Kye Hun Kim, Joon-Han Shin, Dae-Hee Kim, Ung Jeon, Jung Hyun Choi, Yong-Jin Kim, Seung Jae Joo, Ki-Hong Kim, Kyoung Im Cho, Goo-Yeong Cho","doi":"10.4250/jcu.2017.25.3.91","DOIUrl":"https://doi.org/10.4250/jcu.2017.25.3.91","url":null,"abstract":"<p><strong>Background: </strong>Because conventional echocardiographic parameters have several limitations, strain echocardiography has often been introduced in clinical practice. However, there are also obstacles in using it in clinical practice. Therefore, we wanted to find the current status of awareness on using strain echocardiography in Korea.</p><p><strong>Methods: </strong>We conducted a nationwide survey to evaluate current use and awareness of strain echocardiography from the members of the Korean Society of Echocardiography.</p><p><strong>Results: </strong>We gathered total 321 questionnaires from 25 cardiology centers in Korea. All participants were able to perform or interpret echocardiographic examinations. All participating institutions performed strain echocardiography. Most of our study participants (97%) were aware of speckle tracking echocardiography and 185 (58%) performed it for clinical and research purposes. Two-dimensional strain echocardiography was the most commonly used modality and left ventricle (LV) was the most commonly used cardiac chamber (99%) for clinical purposes. Most of the participants (89%) did not think LV strain can replace LV ejection fraction (LVEF) in their clinical practice. The common reasons for not performing routine use of strain echocardiography was diversity of strain measurements and lack of normal reference value. Many participants had a favorable view of the future of strain echocardiography.</p><p><strong>Conclusion: </strong>Most of our study participants were aware of strain echocardiography, and all institutions performed strain echocardiography for clinical and research purposes. However, they did not think the LV strain values could replace LVEF. The diversity of strain measurements and lack of normal reference values were common reasons for not using strain echocardiography in clinical practice.</p>","PeriodicalId":88913,"journal":{"name":"Journal of cardiovascular ultrasound","volume":"25 3","pages":"91-97"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4250/jcu.2017.25.3.91","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35514115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victor Galusko, Mohammed Yunus Khanji, Owen Bodger, Clive Weston, John Chambers, Adrian Ionescu
{"title":"Hand-held Ultrasound Scanners in Medical Education: A Systematic Review.","authors":"Victor Galusko, Mohammed Yunus Khanji, Owen Bodger, Clive Weston, John Chambers, Adrian Ionescu","doi":"10.4250/jcu.2017.25.3.75","DOIUrl":"https://doi.org/10.4250/jcu.2017.25.3.75","url":null,"abstract":"<p><strong>Background: </strong>Ultrasound imaging devices are becoming popular in clinical and teaching settings, but there is no systematic information on their use in medical education. We conducted a systematic review of hand-held ultrasound (HHU) devices in undergraduate medical education to delineate their role, significance, and limitations.</p><p><strong>Methods: </strong>We searched Cochrane, PubMed, Embase, and Medline using the strategy: [(Hand-held OR Portable OR Pocket OR \"Point of Care Systems\") AND Ultrasound] AND (Education OR Training OR Undergraduate OR \"Medical Students\" OR \"Medical School\"). We retained 12 articles focusing on undergraduate medical education. We summarised the patterns of HHU use, pooled and estimated sensitivity, and specificity of HHU for detection of left ventricular dysfunction.</p><p><strong>Results: </strong>Features reported were heterogeneous: training time (1-25 hours), number of students involved (1-an entire cohort), number of subjects scanned (27-211), and type of learning (self-directed vs. traditional lectures + hands-on sessions). Most studies reported cardiac HHU examinations, but other anatomical areas were examined, e.g. abdomen and thyroid. Pooled sensitivity 0.88 [95% confidence interval (CI) 0.83-0.92] and specificity 0.86 (95% CI 0.81-0.90) were high for the detection of left ventricular systolic dysfunction by students.</p><p><strong>Conclusion: </strong>Data on HHU devices in medical education are scarce and incomplete, but following training students can achieve high diagnostic accuracy, albeit in a limited number of (mainly cardiac) pathologies. There is no consensus on protocols best-suited to the educational needs of medical students, nor data on long-term impact, decay in proficiency or on the financial implications of deploying HHU in this setting.</p>","PeriodicalId":88913,"journal":{"name":"Journal of cardiovascular ultrasound","volume":"25 3","pages":"75-83"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4250/jcu.2017.25.3.75","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35514113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}