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Simple and inexpensive immunoassay-based diagnostic tests 简单和廉价的基于免疫分析的诊断测试
Bioanalytical reviews Pub Date : 2011-02-19 DOI: 10.1007/S12566-011-0021-6
Henna Päkkilä, T. Soukka
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引用次数: 8
Ambient desorption ionization mass spectrometry (DART, DESI) and its bioanalytical applications 环境解吸电离质谱法(DART, DESI)及其生物分析应用
Bioanalytical reviews Pub Date : 2011-01-05 DOI: 10.1007/S12566-010-0019-5
E. Chernetsova, G. Morlock
{"title":"Ambient desorption ionization mass spectrometry (DART, DESI) and its bioanalytical applications","authors":"E. Chernetsova, G. Morlock","doi":"10.1007/S12566-010-0019-5","DOIUrl":"https://doi.org/10.1007/S12566-010-0019-5","url":null,"abstract":"","PeriodicalId":88396,"journal":{"name":"Bioanalytical reviews","volume":"62 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2011-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74959934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 53
Protein glycosylation analysis with capillary-based electromigrative separation techniques 基于毛细管电迁移分离技术的蛋白质糖基化分析
Bioanalytical reviews Pub Date : 2010-12-12 DOI: 10.1007/S12566-010-0018-6
Martin Pattky, C. Huhn
{"title":"Protein glycosylation analysis with capillary-based electromigrative separation techniques","authors":"Martin Pattky, C. Huhn","doi":"10.1007/S12566-010-0018-6","DOIUrl":"https://doi.org/10.1007/S12566-010-0018-6","url":null,"abstract":"","PeriodicalId":88396,"journal":{"name":"Bioanalytical reviews","volume":"89 1","pages":"115-155"},"PeriodicalIF":0.0,"publicationDate":"2010-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73208889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Luminescent magnetic particles: structures, syntheses, multimodal imaging, and analytical applications 发光磁性粒子:结构、合成、多模态成像和分析应用
Bioanalytical reviews Pub Date : 2010-12-07 DOI: 10.1007/S12566-010-0017-7
G. Mistlberger, I. Klimant
{"title":"Luminescent magnetic particles: structures, syntheses, multimodal imaging, and analytical applications","authors":"G. Mistlberger, I. Klimant","doi":"10.1007/S12566-010-0017-7","DOIUrl":"https://doi.org/10.1007/S12566-010-0017-7","url":null,"abstract":"","PeriodicalId":88396,"journal":{"name":"Bioanalytical reviews","volume":"44 1","pages":"61-101"},"PeriodicalIF":0.0,"publicationDate":"2010-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89920842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Advances in structure elucidation of small molecules using mass spectrometry. 利用质谱法阐明小分子结构的进展。
Bioanalytical reviews Pub Date : 2010-12-01 Epub Date: 2010-08-21 DOI: 10.1007/s12566-010-0015-9
Tobias Kind, Oliver Fiehn
{"title":"Advances in structure elucidation of small molecules using mass spectrometry.","authors":"Tobias Kind, Oliver Fiehn","doi":"10.1007/s12566-010-0015-9","DOIUrl":"10.1007/s12566-010-0015-9","url":null,"abstract":"<p><p>The structural elucidation of small molecules using mass spectrometry plays an important role in modern life sciences and bioanalytical approaches. This review covers different soft and hard ionization techniques and figures of merit for modern mass spectrometers, such as mass resolving power, mass accuracy, isotopic abundance accuracy, accurate mass multiple-stage MS(n) capability, as well as hybrid mass spectrometric and orthogonal chromatographic approaches. The latter part discusses mass spectral data handling strategies, which includes background and noise subtraction, adduct formation and detection, charge state determination, accurate mass measurements, elemental composition determinations, and complex data-dependent setups with ion maps and ion trees. The importance of mass spectral library search algorithms for tandem mass spectra and multiple-stage MS(n) mass spectra as well as mass spectral tree libraries that combine multiple-stage mass spectra are outlined. The successive chapter discusses mass spectral fragmentation pathways, biotransformation reactions and drug metabolism studies, the mass spectral simulation and generation of in silico mass spectra, expert systems for mass spectral interpretation, and the use of computational chemistry to explain gas-phase phenomena. A single chapter discusses data handling for hyphenated approaches including mass spectral deconvolution for clean mass spectra, cheminformatics approaches and structure retention relationships, and retention index predictions for gas and liquid chromatography. The last section reviews the current state of electronic data sharing of mass spectra and discusses the importance of software development for the advancement of structure elucidation of small molecules. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s12566-010-0015-9) contains supplementary material, which is available to authorized users.</p>","PeriodicalId":88396,"journal":{"name":"Bioanalytical reviews","volume":"2 1-4","pages":"23-60"},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/60/fb/12566_2010_Article_15.PMC3015162.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29644647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative NMR spectroscopy of biologically active substances and excipients 生物活性物质和赋形剂的定量核磁共振光谱
Bioanalytical reviews Pub Date : 2010-10-19 DOI: 10.1007/S12566-010-0016-8
T. Beyer, B. Diehl, U. Holzgrabe
{"title":"Quantitative NMR spectroscopy of biologically active substances and excipients","authors":"T. Beyer, B. Diehl, U. Holzgrabe","doi":"10.1007/S12566-010-0016-8","DOIUrl":"https://doi.org/10.1007/S12566-010-0016-8","url":null,"abstract":"","PeriodicalId":88396,"journal":{"name":"Bioanalytical reviews","volume":"37 1","pages":"1-22"},"PeriodicalIF":0.0,"publicationDate":"2010-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73684250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 47
Sequence-specific electrochemical detection of nucleic acids in real samples 实际样品中核酸序列特异性电化学检测
Bioanalytical reviews Pub Date : 2010-08-17 DOI: 10.1007/S12566-010-0014-X
H. Duwensee, Maren Mix, G. Flechsig
{"title":"Sequence-specific electrochemical detection of nucleic acids in real samples","authors":"H. Duwensee, Maren Mix, G. Flechsig","doi":"10.1007/S12566-010-0014-X","DOIUrl":"https://doi.org/10.1007/S12566-010-0014-X","url":null,"abstract":"","PeriodicalId":88396,"journal":{"name":"Bioanalytical reviews","volume":"52 1","pages":"103-114"},"PeriodicalIF":0.0,"publicationDate":"2010-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81540148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Functionalized nanopipettes: toward label-free, single cell biosensors. 功能化纳米吸管：迈向无标签的单细胞生物传感器。
Bioanalytical reviews Pub Date : 2010-08-01 Epub Date: 2010-06-19 DOI: 10.1007/s12566-010-0013-y
Paolo Actis, Andy C Mak, Nader Pourmand
{"title":"Functionalized nanopipettes: toward label-free, single cell biosensors.","authors":"Paolo Actis, Andy C Mak, Nader Pourmand","doi":"10.1007/s12566-010-0013-y","DOIUrl":"10.1007/s12566-010-0013-y","url":null,"abstract":"<p><p>Nanopipette technology has been proven to be a label-free biosensor capable of identifying DNA and proteins. The nanopipette can include specific recognition elements for analyte discrimination based on size, shape, and charge density. The fully electrical read-out and the ease and low-cost fabrication are unique features that give this technology an enormous potential. Unlike other biosensing platforms, nanopipettes can be precisely manipulated with submicron accuracy and used to study single cell dynamics. This review is focused on creative applications of nanopipette technology for biosensing. We highlight the potential of this technology with a particular attention to integration of this biosensor with single cell manipulation platforms.</p>","PeriodicalId":88396,"journal":{"name":"Bioanalytical reviews","volume":"1 2-4","pages":"177-185"},"PeriodicalIF":0.0,"publicationDate":"2010-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/52/a9/12566_2010_Article_13.PMC2918800.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29205259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analytical potential of gold nanoparticles in functional aptamer-based biosensors 金纳米颗粒在功能性适配体生物传感器中的分析潜力
Bioanalytical reviews Pub Date : 2010-07-06 DOI: 10.1007/S12566-010-0011-0
Yan Du, Bingling Li, E. Wang
{"title":"Analytical potential of gold nanoparticles in functional aptamer-based biosensors","authors":"Yan Du, Bingling Li, E. Wang","doi":"10.1007/S12566-010-0011-0","DOIUrl":"https://doi.org/10.1007/S12566-010-0011-0","url":null,"abstract":"","PeriodicalId":88396,"journal":{"name":"Bioanalytical reviews","volume":"203 1","pages":"187-208"},"PeriodicalIF":0.0,"publicationDate":"2010-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81085732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Recent strategies for the biological sensing of pesticides: from the design to the application in real samples 农药生物传感的最新策略:从设计到实际样品的应用
Bioanalytical reviews Pub Date : 2010-06-03 DOI: 10.1007/S12566-010-0012-Z
M. Del Carlo, D. Compagnone
{"title":"Recent strategies for the biological sensing of pesticides: from the design to the application in real samples","authors":"M. Del Carlo, D. Compagnone","doi":"10.1007/S12566-010-0012-Z","DOIUrl":"https://doi.org/10.1007/S12566-010-0012-Z","url":null,"abstract":"","PeriodicalId":88396,"journal":{"name":"Bioanalytical reviews","volume":"114 1","pages":"159-176"},"PeriodicalIF":0.0,"publicationDate":"2010-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80233488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
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