The open infectious diseases journal最新文献

{"title":"Human Brucellosis as an Epidemic Zoonosis in Zenica-Doboj Canton (Bosnia and Herzegovina) During 2008-2018","authors":"S. Uzunović, M. Skomorac, F. Bašić, F. Kamberović, A. Ibrahimagić, J. Dizdarević","doi":"10.2174/1874279302012010001","DOIUrl":"https://doi.org/10.2174/1874279302012010001","url":null,"abstract":"Department of Clinical Microbiology, Institute for Health and Food Safety Zenica, Fra Ivana Jukića 2, 72000 Zenica, Bosnia and Herzegovina Department of Epidemiology, Institute for Health and Food Safety Zenica, Fra Ivana Jukića 2, 72000 Zenica, Bosnia and Herzegovina Autoimmune Diseases Department, Vasculitis Research Unit, IDIBAPS, CELLEX 4B, Hospital Clinic Barcelona, Spain Department of Chemistry Diagnostics, Institute for Health and Food Safety Zenica, Fra Ivana Jukića 2, 72000 Zenica, Bosnia and Herzegovina Department for Epizootiology, Institute for Health and Food Safety Zenica, Fra Ivana Jukića 2, 72000 Zenica, Bosnia and Herzegovina","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":"12 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2020-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44067457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Demographics, Clinical Presentations, Seasonality, and Outcome between Adult Patients with Influenza A and B in Two Seasons (2014-2015 and 2015-2016) with Emphasis on H1N1 Infection Outcome","authors":"A. Khalil, Ahmed Elhadry, Mohamed Talo, Mohamed Elwakeel, Tamer Ahmed, Shams Alshehail, Mohamad Atteiya, Farouk Batal, Zainab Sakha, Majduldeen Azzo, A. Nazzal","doi":"10.2174/1874279301911010043","DOIUrl":"https://doi.org/10.2174/1874279301911010043","url":null,"abstract":"RESEARCH ARTICLE Comparison of the Demographics, Clinical Presentations, Seasonality, and Outcome between Adult Patients with Influenza A and B in Two Seasons (2014-2015 and 2015-2016) with Emphasis on H1N1 Infection Outcome Abdalla Khalil , Ahmed Elhadry, Mohamed Talo, Mohamed Elwakeel, Tamer Ahmed, Shams Alshehail, Mohamad Atteiya, Farouk Batal, Zainab Sakha, Majduldeen Azzo and Alaa Nazal Emergency Medicine Department, International Medical Center Hospital, Jeddah, Saudi Arabia","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":"11 1","pages":"43-51"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46909183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D and HTLV Infection: A Systematic Review","authors":"E. Netto, M. Gomes-Neto, C. Brites","doi":"10.2174/1874279301911010035","DOIUrl":"https://doi.org/10.2174/1874279301911010035","url":null,"abstract":"Vitamin D has been associated with the pathogenesis of infectious diseases.To perform a systematic review on the association of vitamin D and outcomes of HTLV (Human T-cell lymphotropic virus) infection.We searched PubMed, LILACs, Scielo, Embase and Cochrane Library for studies addressing vitamin D and HTLV infection. We included studies published in English since 1980. Studies associated with HIV, bone metabolism and not related to HTLV- associated myelopathy/ tropical spastic paraparesis (HAM/TSP) or adult T cell leukemia/lymphoma (ATL) were excluded.Twenty-three studies were selected and sixteen studies were included in the review (eight experimental studies, three case reports, three cases series, one cross-sectional study and one review). Fourteen studies were focused on ATL, and two on HAM/TSP. The available data show thatin vitroexposure to 1,25(OH)2D inhibits proliferation of HTLV-infected lymphocytes in patients with ATL or HAM/TSP. It has been observed that hypercalcemia, the main cause of death in patients with ATL, is not associated with serum levels of 1,25(OH)2D or parathyroid hormone-related protein, but leukemia inhibitory factor/D factor seems to be an important factor for hypercalcemia pathogenesis. It was also demonstrated an association between the VDRApaIgene polymorphism and a decreased risk of HAM/TSP in HTLV positive individuals.Despite the small number and heterogeneity of the studies, this systematic review suggests that vitamin D play a role in the pathogenesis of HTLV-associated diseases.","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":"171 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68061331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Global Overview of β-lactam Resistance Genes in Klebsiella pneumoniae","authors":"Yone da Silva, R. Ferrari, V. A. Marin, C. C. Júnior","doi":"10.2174/1874279301911010022","DOIUrl":"https://doi.org/10.2174/1874279301911010022","url":null,"abstract":"Klebsiella pneumoniae is a gram-negative bacillus of the Enterobacteriaceae family, commonly associated with nosocomial infections. This pathogen is a serious public health problem as some of its strains are resistant to about 95% antimicrobials of the pharmaceutical market. This resistance is promoted by the production of the β-lactamase extended spectrum (ESBL) enzymes, one of the major causes of therapeutic failure. This review evaluated the incidence and distribution of resistance genes from Klebsiella pneumoniae to β-lactams worldwide. Our study was conducted with the subject the organism K. pneumoniae and β-lactamic resistance. The most reported genes were blaSHV-12, blaCTX-M-2 and blaSHV-5; with blaSHV-12 being the most described. The last two were present in all continents, characterizing its cosmopolitan profiles. The greatest genetic diversity was observed in the Asian and Oceania, where 41 different genes were isolated. Additionally, our review points out the coexistence of different classes of β-lactamases in a single bacterial isolate. Finally, knowledge of mechanisms associated with resistance of K. pneumoniae is of great public interest and the verification of resistance genes shows a variation over time and location highlights the importance of evaluating the mechanisms or strategies by which these variations occur.","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45931401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial Nosocomial Infection: Experience of the Neonatal Intensive Care Unit at the University Hospital of Marrakech","authors":"Asma Helyaich, N. Slitine, F. Bennaoui, A. Aboussad, N. Soraa, F. Maoulainine","doi":"10.2174/1874279301911010017","DOIUrl":"https://doi.org/10.2174/1874279301911010017","url":null,"abstract":"Nosocomial infections are one of the major causes of morbidity in the Neonatal Intensive Care Unit (NICU). Known risk factors include birth weight, gestational age, severity of illness and its related length of stay, and instrumentation.The purpose of this article is to determine the occurrence of Nosocomial Infections (NIs), including infection rates, main infection sites, and common microorganisms.A retrospective study was conducted between June 2015 and December 2016.The incidence of nosocomial infection was 16%. The primary reasons for admission were intauterin growth retardation (52.5%).Klebsiella Pneumoniaewas the most commonly identified agent in the blood cultures and in the hospital unit (43.6%). The mortality rate from nosocomial infection was 52.6%. The proportion of infected newborns with a lower than normal birth weight was predominant (58.13%).Thus, prevention of bacterial infection is crucial in these settings of unique patients. In this view, improving neonatal management is a key step, and this includes promotion of breast-feeding and hygiene measures.","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44099155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Loco-Regional BCGitis Revealing a HIV Infection in an Infant: A Case Report","authors":"Ibtissam Khattou, O. Louachama, N. Rada, G. Draiss, M. Bouskraoui","doi":"10.2174/1874279301911010013","DOIUrl":"https://doi.org/10.2174/1874279301911010013","url":null,"abstract":"The BCG disease is a specific complication of the Bacille Calmette and Guerin (BCG) vaccine. It is often in the form of benign local BCGitis, however the BCGosis is a lethal disseminated disease that can occur in a patient with immunodeficiency. The prognosis depends on the immune status of the patient, and the quality of management. Therapeutic modalities are very controversial. In this article, the authors report a case of loco-regional BCGitis revealing an HIV infection.","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44799955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Current Perspective of Schistosomiasis in Association with Colorectal Carcinogenesis","authors":"Eshtiyag Abdalla Abdalkareem, K. Yin","doi":"10.2174/1874279301911010007","DOIUrl":"https://doi.org/10.2174/1874279301911010007","url":null,"abstract":"\u0000 \u0000 \u0000 Schistosomiasis is one of the parasitic infections that are often found in humans. More than approximately 200 million people are infected with Schistosomiasis in tropical and subtropical areas of Africa, South America and Asian countries. Literature has long been suggesting the correlation between Schistosomiasis and colorectal malignancy. There is a considerable directory supporting the etiological relation between Schistosoma japonicum infection and colorectal cancer in the Far East, however, the available data about the role of Schistosoma mansoni that can initiate the carcinogenesis of colorectal remain insignificant.\u0000 \u0000 \u0000 \u0000 As such, more studies of this disease should be conducted comprehensively for corporate social responsibility internationally.\u0000 \u0000 \u0000 \u0000 The present study reviewed the available data about the role of Schistosoma, including S. mansoni in association with the carcinogenesis of colorectal.\u0000 \u0000 \u0000 \u0000 The study shows the possible evidence of epidemiology, pathology, molecules and immunopathology associated with Schistosomal infections and colorectal cancer. The infections are apparently getting little attention nor support worldwide due to the geographical barriers and some political issues because it mainly occurs in the people living in the bottom billion and happens in the endemic regions only.\u0000 \u0000 \u0000 \u0000 The in-depth study of this infectious disease will tailor early diagnosis, novel prescription drugs and cost-effective strategies for the treatment of infectious disease colorectal cancer, and hence eradicate the disease in the endemic regions.\u0000","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42970237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal Timing for Peripheral Intravenous Cannula Replacement","authors":"Aladeen Alloubani, Mohammad Awwad, Laila M. Akhu-Zaheya","doi":"10.2174/1874279301911010001","DOIUrl":"https://doi.org/10.2174/1874279301911010001","url":null,"abstract":"\u0000 \u0000 Current literature indicates the optimal replacement time of an intravenous catheter, ranges from when “clinically indicated” (i.e. signs of complications such as infection, occlusion, and/or phlebitis) to three days. The time constraint is designed to prevent infection(s) and phlebitis, as well as to decrease the costs of healthcare, and the time spent by nurses, on patient care.\u0000 \u0000 \u0000 \u0000 To evaluate the impact of routine removal and re-siting of the peripheral intravenous catheter removal, compared to removal when “clinically indicated” by adults and/or pediatrics.\u0000 \u0000 \u0000 \u0000 A search for literature was conducted via Cochrane Review and Web of Sciences™ Core Collection, MEDLINE, and PubMed to summarise the optimal timing for peripheral intravenous cannula replacement. One reviewer individually evaluated the trial(s), review(s), quality of the guidelines, and then, extracted the data.\u0000 \u0000 \u0000 \u0000 Criteria included guideline(s); randomized controlled trial(s); and reviews; all of which matched routine removal of peripheral intravenous cannulation, with re-sited when “clinically indicated”, only in patients in the hospital, partaking in intravenous medication and/or fluids. Articles of relevance to the topic, published in English, French, or Portuguese, prior to 2018, were reviewed.\u0000 \u0000 \u0000 \u0000 The effective implementation of evidence-based, guideline-based practice can decrease the catheter-related infection risk. While larger multi-site trials are required, present-day evidence asserts: the repetitive inserting of a peripheral intravenous device may raise the patient’s level of discomfort, increase the costs of healthcare, and does not decrease complications associated with peripheral intravenous devices.\u0000 \u0000 \u0000 \u0000 The clinically indicated intravenous catheter replacement procedure is cost-effective, compared with the recurring replacement procedure, which recurs every 72 hours; it has been suggested that healthcare institution(s) and hospital(s) have considered revising the policy, whereby intravenous catheters are replaced, if clinically indicated, only.\u0000","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42393735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Stability and Optimal Control Analysis of Malaria Dynamics in the Presence of Human Travelers","authors":"Samson Olaniyi, K. Okosun, S. Adesanya, E. Areo","doi":"10.2174/1874279301810010166","DOIUrl":"https://doi.org/10.2174/1874279301810010166","url":null,"abstract":"The impact of unguarded human movement on the spread of infectious disease like malaria cannot be underestimated. Therefore, this study examines the significance of short term human travelers on malaria transmission dynamics.A non-autonomous system of ordinary differential equations incorporating four control strategies, namely personal protection, chemo-prophylaxis, chemotherapy and mosquito-reduction effort is presented to describe the dynamics of malaria transmission between two interacting populations. Suitable Lyapunov functions are constructed to analyze the global dynamics of the autonomous version. Moreover, the model which incorporates time-dependent vigilant controls is qualitatively analyzed with the overall goal of minimizing the spread of malaria and the associated costs of control implementation using the optimal control theory. An iterative method of forward-backward Runge-Kutta fourth order scheme is used to simulate the optimality system in order to investigate the effects of the control strategies on the magnitude of infected individuals in the population.Analysis of the autonomous system shows that the disease-free equilibrium is globally asymptotically stable whenever the basic reproduction is less than unity and a uniquely determined endemic equilibrium is shown to be globally asymptotically stable whenever the associated basic reproduction number exceeds unity. In the case of non-autonomous system, necessary conditions for the optimal control of malaria are derived. It is shown that adherence to the combination of the control strategies by short term human travelers helps in curtailing the spread of malaria in the population.","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41377236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Very Long Persistence of Botulinum Toxin B in a Patient’s Serum","authors":"L. Delbrassinne, V. Laisnez, M. D. Weweire, J. Vanderpas, K. Dierick, S. Denayer","doi":"10.2174/1874279301810010187","DOIUrl":"https://doi.org/10.2174/1874279301810010187","url":null,"abstract":"\u0000 \u0000 Botulinum toxins (BoNT) type A, B, E, F may induce a serious neuroparalytic illness in humans. Botulism can be transmitted via three routes: foodborne, wound and intestinal (in situ toxemia generally observed in infants and/or in immunocompromised adults) botulism.\u0000 \u0000 \u0000 \u0000 A case of human botulism type B due to the consumption of an imported dried ham is reported. Laboratory results confirmed the diagnosis using the mouse bioassay and the qPCR method. Botulinum toxin was still detected in the serum up to 29 days after food consumption while it was not detected anymore in the faeces.\u0000 \u0000 \u0000 \u0000 The described case highlights i) prolonged presence of BoNT B in the serum and ii) the risks related to the preparation of artisanal products as well as the importance of an efficient communication to citizens regarding preservation methods of household products.\u0000","PeriodicalId":88330,"journal":{"name":"The open infectious diseases journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42559255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}