Genomic medicine最新文献

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Cell-Free DNA Testing 无细胞DNA检测
Genomic medicine Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-22922-1_3
B. Decker, L. Sholl
{"title":"Cell-Free DNA Testing","authors":"B. Decker, L. Sholl","doi":"10.1007/978-3-030-22922-1_3","DOIUrl":"https://doi.org/10.1007/978-3-030-22922-1_3","url":null,"abstract":"","PeriodicalId":87975,"journal":{"name":"Genomic medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51079435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
GI Including GIST GI包括GIST
Genomic medicine Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-22922-1_7
E. Vakiani
{"title":"GI Including GIST","authors":"E. Vakiani","doi":"10.1007/978-3-030-22922-1_7","DOIUrl":"https://doi.org/10.1007/978-3-030-22922-1_7","url":null,"abstract":"","PeriodicalId":87975,"journal":{"name":"Genomic medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51079065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interpreting Genomic Reports 解读基因组报告
Genomic medicine Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-22922-1_5
A. Contreras
{"title":"Interpreting Genomic Reports","authors":"A. Contreras","doi":"10.1007/978-3-030-22922-1_5","DOIUrl":"https://doi.org/10.1007/978-3-030-22922-1_5","url":null,"abstract":"","PeriodicalId":87975,"journal":{"name":"Genomic medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51079506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Myeloid Neoplasms 急性髓系肿瘤
Genomic medicine Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-22922-1_14
Eric Y Loo
{"title":"Acute Myeloid Neoplasms","authors":"Eric Y Loo","doi":"10.1007/978-3-030-22922-1_14","DOIUrl":"https://doi.org/10.1007/978-3-030-22922-1_14","url":null,"abstract":"","PeriodicalId":87975,"journal":{"name":"Genomic medicine","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51079411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Bioinformatics in Molecular Medicine 生物信息学在分子医学中的作用
Genomic medicine Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-22922-1_4
C. Vanderbilt, S. Middha
{"title":"Role of Bioinformatics in Molecular Medicine","authors":"C. Vanderbilt, S. Middha","doi":"10.1007/978-3-030-22922-1_4","DOIUrl":"https://doi.org/10.1007/978-3-030-22922-1_4","url":null,"abstract":"","PeriodicalId":87975,"journal":{"name":"Genomic medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51079494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computational biology and structural proteomics. 计算生物学和结构蛋白质组学。
Genomic medicine Pub Date : 2008-12-01 DOI: 10.1007/s11568-009-9088-3
{"title":"Computational biology and structural proteomics.","authors":"","doi":"10.1007/s11568-009-9088-3","DOIUrl":"https://doi.org/10.1007/s11568-009-9088-3","url":null,"abstract":"","PeriodicalId":87975,"journal":{"name":"Genomic medicine","volume":"2 3-4","pages":"295-302"},"PeriodicalIF":0.0,"publicationDate":"2008-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11568-009-9088-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28180116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Micro RNA and non-coding DNA and repeats. 微RNA和非编码DNA和重复序列。
Genomic medicine Pub Date : 2008-12-01 DOI: 10.1007/s11568-009-9108-3
{"title":"Micro RNA and non-coding DNA and repeats.","authors":"","doi":"10.1007/s11568-009-9108-3","DOIUrl":"https://doi.org/10.1007/s11568-009-9108-3","url":null,"abstract":"","PeriodicalId":87975,"journal":{"name":"Genomic medicine","volume":"2 3-4","pages":"401-13"},"PeriodicalIF":0.0,"publicationDate":"2008-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11568-009-9108-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28205000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Late posters. 晚海报。
Genomic medicine Pub Date : 2008-12-01 DOI: 10.1007/s11568-009-9107-4
{"title":"Late posters.","authors":"","doi":"10.1007/s11568-009-9107-4","DOIUrl":"https://doi.org/10.1007/s11568-009-9107-4","url":null,"abstract":"","PeriodicalId":87975,"journal":{"name":"Genomic medicine","volume":"2 3-4","pages":"435-8"},"PeriodicalIF":0.0,"publicationDate":"2008-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11568-009-9107-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28209706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Identification of gene biomarkers for respiratory syncytial virus infection in a bronchial epithelial cell line. 支气管上皮细胞系呼吸道合胞病毒感染基因生物标志物的鉴定。
Genomic medicine Pub Date : 2008-12-01 Epub Date: 2009-05-15 DOI: 10.1007/s11568-009-9080-y
Yuh-Chin T Huang, Zhuowei Li, Xhevahire Hyseni, Michael Schmitt, Robert B Devlin, Edward D Karoly, Joleen M Soukup
{"title":"Identification of gene biomarkers for respiratory syncytial virus infection in a bronchial epithelial cell line.","authors":"Yuh-Chin T Huang,&nbsp;Zhuowei Li,&nbsp;Xhevahire Hyseni,&nbsp;Michael Schmitt,&nbsp;Robert B Devlin,&nbsp;Edward D Karoly,&nbsp;Joleen M Soukup","doi":"10.1007/s11568-009-9080-y","DOIUrl":"https://doi.org/10.1007/s11568-009-9080-y","url":null,"abstract":"<p><p>Respiratory syncytial virus (RSV) infection involves complex virus-host interplay. In this study, we analyzed gene expression in RSV-infected BEAS-2B cells to discover novel signaling pathways and biomarkers. We hybridized RNAs from RSV- or vehicle-treated BEAS-2B to Affymetrix HU133 plus 2.0 microarrays (n = 4). At 4 and 24 h post-infection, 277 and 900 genes (RSV/control ratio >/=2.0 or </=0.5), and 1 and 12 pathways respectively were significantly altered. Twenty-three and 92 genes at 4 and 24 h respectively matched respiratory disease biomarkers with ARG2 flagged at 24 h and SCNN1G, EPB41L4B, CSF1, PTEN, TUBB1 and ESR2 at both time points. Hierachical clustering showed a cluster containing ARG2 and IL8. In human bronchial epithelial cells, RSV upregulated arginase II protein. Knockdown of ARG2 increased RSV-induced IL-8, LDH and histone release. With microarray, we identified novel proximal airway epithelial cell genes that may be tested in the sputum samples as biomarkers of RSV infection.</p>","PeriodicalId":87975,"journal":{"name":"Genomic medicine","volume":"2 3-4","pages":"113-25"},"PeriodicalIF":0.0,"publicationDate":"2008-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11568-009-9080-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28188674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 37
Genomics of complex disorders I. 复杂疾病基因组学1。
Genomic medicine Pub Date : 2008-12-01 DOI: 10.1007/s11568-009-9104-7
{"title":"Genomics of complex disorders I.","authors":"","doi":"10.1007/s11568-009-9104-7","DOIUrl":"https://doi.org/10.1007/s11568-009-9104-7","url":null,"abstract":"","PeriodicalId":87975,"journal":{"name":"Genomic medicine","volume":"2 3-4","pages":"303-30"},"PeriodicalIF":0.0,"publicationDate":"2008-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11568-009-9104-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28195270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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