Seminars in breast disease最新文献_第5页

Partial Breast Irradiation: Is This a Viable Option? 部分乳房照射:这是一个可行的选择吗?

Seminars in breast disease Pub Date : 2007-12-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.10.003

Bradley J. Huth, Dennis M. Sopka, Jay Reiff, Lydia T. Komarnicky-Kocher

{"title":"Partial Breast Irradiation: Is This a Viable Option?","authors":"Bradley J. Huth, Dennis M. Sopka, Jay Reiff, Lydia T. Komarnicky-Kocher","doi":"10.1053/j.sembd.2007.10.003","DOIUrl":"https://doi.org/10.1053/j.sembd.2007.10.003","url":null,"abstract":"<div>In the treatment of early invasive and in situ breast carcinomas, lumpectomy followed by whole breast radiation are generally accepted as standard of care in breast conservation. Long-term data from early breast conservation trials has shown that most local failures occur in close proximity to the tumor bed. This has been observed in both radiated and unradiated breasts treated with breast conservation techniques, suggesting that occult multifocal disease is less ominous than once believed. Improvements in breast imaging and radiation treatment planning and delivery allow the experienced radiation oncologist to deliver high doses of radiation to the region of the tumor bed alone in less than 2 weeks. Preliminary data suggests that this abbreviated course of radiation offers cosmetic and disease control outcomes equal to that of traditional whole breast radiation in selected populations. This article reviews current techniques, outcomes of clinical trials, and novel techniques in partial breast radiation for early and locally recurrent breast carcinomas.</div>","PeriodicalId":87785,"journal":{"name":"Seminars in breast disease","volume":"10 4","pages":"Pages 152-161"},"PeriodicalIF":0.0,"publicationDate":"2007-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.sembd.2007.10.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138386279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Consensus Conference on Breast Conservation 乳房保护共识会议

Seminars in breast disease Pub Date : 2007-12-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.10.005

Gordon F. Schwartz, Umberto Veronesi, Krishna B. Clough, J.M. Dixon, Ian S. Fentiman, Sylvia H. Heywang-Köbrunner, Roland Holland, Kevin S. Hughes, Richard Margolese, Ivo A. Olivotto, Juan P. Palazzo, Lawrence J. Solin, Consensus Conference Committee

引用次数: 0

Challenges in the Management of Metastatic Breast Cancer 转移性乳腺癌管理的挑战

Seminars in breast disease Pub Date : 2007-09-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.10.009

Homayoon Sanati MD, MS

{"title":"Challenges in the Management of Metastatic Breast Cancer","authors":"Homayoon Sanati MD, MS","doi":"10.1053/j.sembd.2007.10.009","DOIUrl":"10.1053/j.sembd.2007.10.009","url":null,"abstract":"<div>Breast cancer is the most common cancer in women in the United States. About 6% of newly diagnosed breast cancer cases present with metastatic disease, and one-third of women diagnosed with earlier stage breast cancer develop metastatic disease. Management of metastatic breast cancer (MBC) continues to be challenging, and MBC remains essentially an incurable disease. Treatment of MBC is individualized for each patient, and it is often based on patient’s preferences, comorbidities, performance status, prognostic factors, menopausal status, and prior history of treatments. Risk assessment is the first step in the management of MBC. Factors that can affect the prognosis (hormone receptor status, HER-2 expression status, disease-free interval, tumor burden, site of metastasis, and vital organ involvement) are considered before start of the treatments. Women with hormone responsive disease and stable bony metastasis are often treated with hormonal therapies and bisphosphonates. Women with hormone-unresponsive disease or fast-growing tumors are treated with systemic chemotherapy with or without a targeted therapy agent. Metastasis to the brain, spinal cord compression, pleural effusion, hypercalcemia, and pancytopenia secondary to bone marrow infiltration are common complications of MBC, and the management of each complication will be briefly discussed. Future research to identify molecular prognostic markers and to evaluate various strategies for optimal management of MBC is needed.</div>","PeriodicalId":87785,"journal":{"name":"Seminars in breast disease","volume":"10 3","pages":"Pages 128-133"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.sembd.2007.10.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57942533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unusual Benign Breast Lesions 乳腺异常良性病变

Seminars in breast disease Pub Date : 2007-09-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.10.008

Ashley Kempf BS, Karen Lane MD

引用次数: 0

Defining Quality of Care for Breast Cancer: Clinical Challenges 定义乳腺癌护理质量:临床挑战

Seminars in breast disease Pub Date : 2007-09-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.10.011

Irina Yermilov MD, MS , Melinda A. Maggard MD, MSHS

引用次数: 1

Managing Menopausal Symptoms in Breast Cancer Survivors: Focus on Hot Flashes 管理乳腺癌幸存者的更年期症状:关注潮热

Seminars in breast disease Pub Date : 2007-09-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.10.010

Edith Caroline Smith MSN, CNM, WHCNP

引用次数: 1

Organized Breast Cancer Screening in British Columbia: The Screening Mammography Program of British Columbia 在不列颠哥伦比亚省组织乳腺癌筛查:不列颠哥伦比亚省筛查乳房x光检查项目

Seminars in breast disease Pub Date : 2007-06-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.09.005

Linda J. Warren Burhenne MD, FRCPC, Andrew J. Coldman PhD, Lisa Kan MSc

引用次数: 4

Evaluation of the Impact of Service Screening: The Florence City Programme (1990–1996) 评价服务筛选的影响:佛罗伦萨城市方案(1990-1996年)

Seminars in breast disease Pub Date : 2007-06-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.09.002

Eugenio Paci MD

{"title":"Evaluation of the Impact of Service Screening: The Florence City Programme (1990–1996)","authors":"Eugenio Paci MD","doi":"10.1053/j.sembd.2007.09.002","DOIUrl":"10.1053/j.sembd.2007.09.002","url":null,"abstract":"<div>In Europe, the challenge today is the evaluation of the impact of mammography service screening. Here, we analyze data of the Florence City Breast Cancer Screening Programme from 1990 to 1996. Breast cancer cases registered in women aged 50 to 69 were partitioned by diagnostic modality and screening invitation. The cumulative number of breast cancer deaths within cases was calculated to estimate the rates of cancers proving fatal within a period of 8 years of observation (incidence-based mortality). For women who were not yet invited at the time of diagnosis, there was a 41% significant mortality reduction (RR = 0.59, 95% CI: 0.42-0.82) when compared with the data in 1985 to 1986. In those invited, there was a significant 55% mortality reduction (RR = 0.45, 95% CI: 0.32-0.61). Percentages of breast conserving surgery by screening modality were higher in cases occurring in invited women and are considered an important outcome of service screening. This study is one of the first examples of the evaluation of service screening and supports the conclusion that screening is contributing to the reduction of mortality from breast cancer.</div>","PeriodicalId":87785,"journal":{"name":"Seminars in breast disease","volume":"10 2","pages":"Pages 64-67"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1053/j.sembd.2007.09.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57942003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methodologic Issues in the Evaluation of Service Screening 服务筛选评价中的方法学问题

Seminars in breast disease Pub Date : 2007-06-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.09.003

Stephen W. Duffy , Tony H.H. Chen , Amy M.F. Yen , Laszlo Tabar , Rhian Gabe , Robert A. Smith

引用次数: 4

Evaluating Population-Based Screening Mammography Programs Internationally 评估国际上基于人群的乳房x光筛查项目

Seminars in breast disease Pub Date : 2007-06-01 Epub Date: 2008-09-25 DOI: 10.1053/j.sembd.2007.09.007

Carrie N. Klabunde PhD, Rachel Ballard-Barbash MD, MPH, International Breast Cancer Screening Network

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引用次数: 33