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SEB experimental biology series最新文献

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Bioinformatic approaches to biological systems. 生物系统的生物信息学方法。
SEB experimental biology series Pub Date : 2008-01-01
David R Westhead, Iain W Manfield, Christopher J Needham
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引用次数: 0
Copying the template--with a little help from my friends? 复制模板--在朋友的帮助下？
SEB experimental biology series Pub Date : 2008-01-01
John A Bryant
{"title":"Copying the template--with a little help from my friends?","authors":"John A Bryant","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87484,"journal":{"name":"SEB experimental biology series","volume":"59 ","pages":"71-80"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27345459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A mechanism coupling cell division and the control of apoptosis. 细胞分裂与细胞凋亡控制的耦合机制。
SEB experimental biology series Pub Date : 2008-01-01
Lindsey A Allan, Paul R Clarke
{"title":"A mechanism coupling cell division and the control of apoptosis.","authors":"Lindsey A Allan,&nbsp;Paul R Clarke","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Our recent results demonstrate that caspase activation is regulated during the cell cycle, establishing a direct link between the regulation of apoptosis and cell division (Allan and Clarke, 2007). We show that phosphorylation of caspase-9 is critical for the balance between these processes, restraining the initiation of apoptosis during mitosis. This mechanism is likely to be important in determining sensitivity to anti-cancer drugs that target mitotic cells. We propose that regulation of the phosphorylation of caspase-9 during prolonged mitotic arrest may provide a timing mechanism that initiates apoptosis and destroys an aberrant cell if mitosis is not successfully resolved. This mechanism may play an important role in anti-cancer surveillance and might be exploited to improve cell killing by anti-cancer drugs that target mitotic cells.</p>","PeriodicalId":87484,"journal":{"name":"SEB experimental biology series","volume":"59 ","pages":"257-65"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27345988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using a Drosophila model of Alzheimer's disease. 使用阿尔茨海默病的果蝇模型。
SEB experimental biology series Pub Date : 2008-01-01 DOI: 10.1201/9781003060796-5
D. Crowther, R. Page, T. Rival, Dhianjali S Chandraratna, D. Lomas
{"title":"Using a Drosophila model of Alzheimer's disease.","authors":"D. Crowther, R. Page, T. Rival, Dhianjali S Chandraratna, D. Lomas","doi":"10.1201/9781003060796-5","DOIUrl":"https://doi.org/10.1201/9781003060796-5","url":null,"abstract":"","PeriodicalId":87484,"journal":{"name":"SEB experimental biology series","volume":"60 1","pages":"57-77"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65950687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
DNA ligase--a means to an end joining. DNA连接酶，一种最终连接的手段。
SEB experimental biology series Pub Date : 2008-01-01
Clifford M Bray, Paul A Sunderland, Wanda M Waterworth, Christopher E West
{"title":"DNA ligase--a means to an end joining.","authors":"Clifford M Bray, Paul A Sunderland, Wanda M Waterworth, Christopher E West","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87484,"journal":{"name":"SEB experimental biology series","volume":"59 ","pages":"203-17"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27345985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peripheral modulation of taste responses. 味觉反应的外周调节。
SEB experimental biology series Pub Date : 2007-04-01 DOI: 10.4324/9780203866757-12
H. Schuppe, P. Newland
{"title":"Peripheral modulation of taste responses.","authors":"H. Schuppe, P. Newland","doi":"10.4324/9780203866757-12","DOIUrl":"https://doi.org/10.4324/9780203866757-12","url":null,"abstract":"","PeriodicalId":87484,"journal":{"name":"SEB experimental biology series","volume":"29 1","pages":"139-81"},"PeriodicalIF":0.0,"publicationDate":"2007-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70598869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Discovery of novel sodium channel inhibitors: a gene family-based approach. 新型钠通道抑制剂的发现:基于基因家族的方法。
SEB experimental biology series Pub Date : 2007-01-01
Jeff J Clare
{"title":"Discovery of novel sodium channel inhibitors: a gene family-based approach.","authors":"Jeff J Clare","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87484,"journal":{"name":"SEB experimental biology series","volume":"58 ","pages":"115-32"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26811318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
'Omics' in translational medicine: are they lost in translation? 翻译医学中的“组学”:它们在翻译中丢失了吗?
SEB experimental biology series Pub Date : 2007-01-01
John A Bilello
{"title":"'Omics' in translational medicine: are they lost in translation?","authors":"John A Bilello","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87484,"journal":{"name":"SEB experimental biology series","volume":"58 ","pages":"133-43"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26811319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative genomics and drug discovery in trypanosomatids. 锥虫的比较基因组学和药物发现。
SEB experimental biology series Pub Date : 2007-01-01
Sergio Callejas, Sara Melville
{"title":"Comparative genomics and drug discovery in trypanosomatids.","authors":"Sergio Callejas,&nbsp;Sara Melville","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87484,"journal":{"name":"SEB experimental biology series","volume":"58 ","pages":"1-24"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26810939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The practical implications of comparative kinetoplastid genomics. 比较动质体基因组学的实际意义。
SEB experimental biology series Pub Date : 2007-01-01
C S Peacock
{"title":"The practical implications of comparative kinetoplastid genomics.","authors":"C S Peacock","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87484,"journal":{"name":"SEB experimental biology series","volume":"58 ","pages":"25-45"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26810940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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