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Journal of neuropathic pain & symptom palliation最新文献

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Lumbar Radicular Pain 腰椎神经根性疼痛
Journal of neuropathic pain & symptom palliation Pub Date : 2018-12-01 DOI: 10.1093/MED/9780190298357.003.0028
V. Rimmalapudi, R. Grandhe
{"title":"Lumbar Radicular Pain","authors":"V. Rimmalapudi, R. Grandhe","doi":"10.1093/MED/9780190298357.003.0028","DOIUrl":"https://doi.org/10.1093/MED/9780190298357.003.0028","url":null,"abstract":"This chapter addresses lumbar radicular pain, which is pain that can be attributed to a lesion affecting fibers of a spinal nerve, the nerve root, or the dorsal root ganglia. Causes of radicular pain are diverse and may include mechanical causes such as herniated intervertebral discs and lumbar foraminal stenosis or systemic causes such as diabetic neuropathy and lupus. A thorough history and meticulous examination are necessary to delineate the involved nerve root and to rule out other conditions. Imaging modalities must be judiciously used to determine the site of compression. Management may start with noninvasive management measures, including physical therapy and medications. It should be guided by patient response, progression of symptoms, and the natural progression of disease.","PeriodicalId":87440,"journal":{"name":"Journal of neuropathic pain & symptom palliation","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72550344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple Sclerosis 多发性硬化症
Journal of neuropathic pain & symptom palliation Pub Date : 2018-12-01 DOI: 10.1093/med/9780190298357.003.0024
Sam Samuel, Jianguo Cheng
{"title":"Multiple Sclerosis","authors":"Sam Samuel, Jianguo Cheng","doi":"10.1093/med/9780190298357.003.0024","DOIUrl":"https://doi.org/10.1093/med/9780190298357.003.0024","url":null,"abstract":"Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system (CNS). The diagnosis is based on evidence of at lease two different lesions in the CNS, at least two different episodes in the disease course, and chronic inflammation of the CNS as determined by analysis of the cerebrospinal fluid. Central neuropathic pain is the most common form of pain in patients with MS, with an estimated prevalence of about 50%. Along with the classical neuropathic pain features, such as spontaneous pain (dysesthesia and burning) and evoked pain (allodynia and hyperalgesia), patients with MS may also suffer from intermittent neuropathic pain, such as trigeminal neuralgia, Lhermitte sign, and glossopharyngeal neuralgia. In addition to disease-modifying therapies of MS, multiple treatments are available to manage neuropathic pain secondary to MS, including medical, interventional, and surgical treatments with varying levels of evidence.","PeriodicalId":87440,"journal":{"name":"Journal of neuropathic pain & symptom palliation","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80513681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spinal Cord Injury 脊髓损伤
Journal of neuropathic pain & symptom palliation Pub Date : 2018-12-01 DOI: 10.1093/med/9780190298357.003.0020
Justin Averna, A. Bautista, George C. Chang Chien, M. Saulino
{"title":"Spinal Cord Injury","authors":"Justin Averna, A. Bautista, George C. Chang Chien, M. Saulino","doi":"10.1093/med/9780190298357.003.0020","DOIUrl":"https://doi.org/10.1093/med/9780190298357.003.0020","url":null,"abstract":"Pain from spinal cord injury (SCI) is one of the pain syndromes that is recalcitrant to treatment. It is often a result of injury associated with mechanical trauma and vascular compromise of the spinal cord parenchyma. SCI pain is associated with substantial impact on the patient’s life, interfering with activities of daily living, effective rehabilitation, and quality of life. The underlying mechanism for the development of SCI pain includes neuronal hyperexcitability, reduced inhibition, neuronal reorganization, and plasticity. The diverse factors associated with SCI pain warrant the need for an interdisciplinary approach tailored to the individual patient. The goals of treatment should encompass four domains: pain management, spinal rehabilitation, psychological treatment, and social and environmental modification.","PeriodicalId":87440,"journal":{"name":"Journal of neuropathic pain & symptom palliation","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82865776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interventional Treatment of Neuropathic Pain 神经性疼痛的介入治疗
Journal of neuropathic pain & symptom palliation Pub Date : 2018-12-01 DOI: 10.1093/MED/9780190298357.003.0007
Jiang Wu, Jianguo Cheng
{"title":"Interventional Treatment of Neuropathic Pain","authors":"Jiang Wu, Jianguo Cheng","doi":"10.1093/MED/9780190298357.003.0007","DOIUrl":"https://doi.org/10.1093/MED/9780190298357.003.0007","url":null,"abstract":"Neuropathic pain has been reported to be highly prevalent, severely disabling, and often refractory to pharmacological and noninterventional conservative treatment. There is an emerging body of exciting evidence to support interventional therapies in selected refractory neuropathic pain states, although more randomized controlled trials or comparative effective trials are needed. This chapter updates the scientific evidence in support of the efficacy of neural blockade techniques and neural ablative procedures in neuropathic pain states, including peripheral compression or trauma-related neuropathic pain, herpes zoster and postherpetic neuralgia (PHN), lumbosacral and cervical radiculopathy, sympathetically maintained pain, complex regional pain syndrome (CRPS), trigeminal neuralgia and trigeminal neuropathy, and painful diabetic polyneuropathies.","PeriodicalId":87440,"journal":{"name":"Journal of neuropathic pain & symptom palliation","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90957421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concept and Overview of Neuropathic Pain 神经性疼痛的概念和概述
Journal of neuropathic pain & symptom palliation Pub Date : 2018-12-01 DOI: 10.1093/MED/9780190298357.003.0001
Jianguo Cheng
{"title":"Concept and Overview of Neuropathic Pain","authors":"Jianguo Cheng","doi":"10.1093/MED/9780190298357.003.0001","DOIUrl":"https://doi.org/10.1093/MED/9780190298357.003.0001","url":null,"abstract":"Neuropathic pain is defined as pain arising from a lesion or disease of the somatosensory nervous system. It is highly prevalent, afflicting 7–18% of the general population. Its incidences are much higher, ranging from 20% to 77%, in patients with spine disorder, hip and knee osteoarthritis, or cancer. Neuropathic pain can be severely disabling, with significant personal, societal, and economic cost. Patients with neuropathic pain disorders have significantly reduced health-related quality of life and their treatment costs three times that for matched control subjects. There are enormous challenges in understanding and managing neuropathic pain given the diversity of causes, pathology, mechanisms, and clinical presentations of neuropathic pain conditions. Along with these challenges are opportunities for advancing the mechanistic understanding of neuropathic pain and developing promising therapeutic modalities that include new pharmacological agents, emerging stem cell therapy, and novel neuromodulation paradigms.","PeriodicalId":87440,"journal":{"name":"Journal of neuropathic pain & symptom palliation","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87338604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nonpharmacological Treatment of Neuropathic Pain 神经性疼痛的非药物治疗
Journal of neuropathic pain & symptom palliation Pub Date : 2018-12-01 DOI: 10.1093/MED/9780190298357.003.0005
R. Mirpuri, D. Perret
{"title":"Nonpharmacological Treatment of Neuropathic Pain","authors":"R. Mirpuri, D. Perret","doi":"10.1093/MED/9780190298357.003.0005","DOIUrl":"https://doi.org/10.1093/MED/9780190298357.003.0005","url":null,"abstract":"This chapter discusses various nonpharmacological treatments for neuropathic pain. Physiotherapy, tai chi, and yoga are all methods that incorporate movement exercise to treat biomechanical imbalances and reduce kinesiophobia, or “fear of movement.” Additionally, this chapter discusses treatments targeted at the peripheral nervous system, such as structured graded desensitization, heat/cold physical modalities, transcutaneous electrical nerve stimulation, and acupuncture, all of which have varying levels of efficacy. The chapter reviews the different psychotherapy approaches to treating neuropathic pain: cognitive-behavioral therapy (CBT), operant-behavioral therapy, mindfulness-based stress reduction (MBSR), and acceptance and commitment therapy (ACT). It is important to note that many of the therapies discussed are intended to be incorporated with other pharmacological or interventional approaches to provide a multimodal level of care and increase chances of outcome success. Other treatments discussed include orthotics, mirror therapy, and transcranial magnetic stimulation for a variety of neuropathic conditions.","PeriodicalId":87440,"journal":{"name":"Journal of neuropathic pain & symptom palliation","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87376327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Herpes Zoster and Postherpetic Neuralgia 带状疱疹和带状疱疹后神经痛
Journal of neuropathic pain & symptom palliation Pub Date : 2018-12-01 DOI: 10.1007/978-3-319-64922-1_24
Jianguo Cheng, Richard Rosenquist
{"title":"Herpes Zoster and Postherpetic Neuralgia","authors":"Jianguo Cheng, Richard Rosenquist","doi":"10.1007/978-3-319-64922-1_24","DOIUrl":"https://doi.org/10.1007/978-3-319-64922-1_24","url":null,"abstract":"","PeriodicalId":87440,"journal":{"name":"Journal of neuropathic pain & symptom palliation","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85558545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trigeminal Neuralgia 三叉神经痛
Journal of neuropathic pain & symptom palliation Pub Date : 2018-12-01 DOI: 10.1093/med/9780190298357.003.0030
Radhika Grandhe, Eli Johnson Harris, Eugene Koshkin
{"title":"Trigeminal Neuralgia","authors":"Radhika Grandhe, Eli Johnson Harris, Eugene Koshkin","doi":"10.1093/med/9780190298357.003.0030","DOIUrl":"https://doi.org/10.1093/med/9780190298357.003.0030","url":null,"abstract":"Trigeminal neuralgia is a rare neuropathic pain condition but can be very disabling. The hallmark is brief episodes of intense, radiating pain within the territory of trigeminal nerve distribution. It is typically unilateral, often accompanied by facial spasms and can be triggered by facial movements in a majority of patients. Microvascular compression of trigeminal ganglion is the etiology for most patients with classical trigeminal neuralgia. Some patients can have continuous facial pain in addition to paroxysms of pain. Trigeminal neuralgia is a clinical diagnosis, but MRI is done to rule out secondary causes or to detect microvascular compression. Pharmacological therapy with first-line agents—carbamazepine or oxcarbazepine—is the preferred treatment. Patients with failed pharmacological therapy are considered for surgical decompression, ablation procedures, or Gamma Knife surgery.","PeriodicalId":87440,"journal":{"name":"Journal of neuropathic pain & symptom palliation","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74017483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thoracic Radicular Pain 胸椎神经根痛
Journal of neuropathic pain & symptom palliation Pub Date : 2018-12-01 DOI: 10.1093/med/9780190298357.003.0027
Victor Foorsov, S. Pastoriza
{"title":"Thoracic Radicular Pain","authors":"Victor Foorsov, S. Pastoriza","doi":"10.1093/med/9780190298357.003.0027","DOIUrl":"https://doi.org/10.1093/med/9780190298357.003.0027","url":null,"abstract":"Thoracic radiculopathy presents an uncommon spinal disorder that can often be overlooked because numerous structures surround the thoracic spine. Radiculopathy typically originates from mechanical nerve root compression due to degenerative spine changes such as disc herniation, spondylosis, or osteoporosis and its associated vertebral compression fractures. The presentation of radicular pain in the thoracic region is more common in the upper thoracic and, with lateral disk herniations, often associated with some amount of axial pain. Clinical symptoms are leg weakness, numbness and tingling across the chest or abdomen or shoulders, spasticity, and bowel or bladder dysfunction. The vast majority of patients with thoracic pain return to their previous functional level without surgical intervention. Strengthening, postural optimization, and general exercise and mobility comprise the cornerstone of all treatment and prevention of thoracic radicular pain. Medication may include a variety of choices, ranging from NSAIDs to anticonvulsants. Medications to address specific health issues leading to thoracic radiculopathy (diabetes mellitus and osteoporosis) may be of additional benefit. Thoracic epidural injections or paravertebral blocks with corticosteroids and local anesthetics may be a treatment consideration. Surgical intervention is reserved for patients in whom conservative management has failed and who have persistent pain symptoms. Myelopathy is an indication for surgical intervention. Spinal cord stimulation may be effective to address chronic radiculopathy in selected patients.","PeriodicalId":87440,"journal":{"name":"Journal of neuropathic pain & symptom palliation","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85899015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Glossopharyngeal Neuralgia
Journal of neuropathic pain & symptom palliation Pub Date : 2018-12-01 DOI: 10.1093/med/9780190298357.003.0031
George C. Chang Chien, A. Trescot, A. Stogicza
{"title":"Glossopharyngeal Neuralgia","authors":"George C. Chang Chien, A. Trescot, A. Stogicza","doi":"10.1093/med/9780190298357.003.0031","DOIUrl":"https://doi.org/10.1093/med/9780190298357.003.0031","url":null,"abstract":"Glossopharyngeal neuralgia (GPN) is both an uncommon and poorly recognized cause of face and neck pain. Because of its potential underdiagnosis, this condition may be more common than reported in the literature. GPN presents with symptoms similar to tic douloureux (trigeminal neuralgia); however, the pathology is not from the trigeminal nerve but rather from the glossopharyngeal nerve. GPN is characterized by unilateral paroxysmal pain in the oropharynx, nasopharynx, larynx, base of the tongue, tonsillar region, and lower jaw, as well as the ipsilateral ear. There are several causes, including tumors, elongated styloid process (Eagle’s syndrome), and vascular compression; however, most cases are considered idiopathic. Treatment for GPN includes treatment of the secondary causes, while medical treatment is similar to that for trigeminal neuralgia. Techniques for cervical, extraoral, intraoral, fluoroscopic, or ultrasound-assisted glossopharyngeal nerve block have been described, and neurolytic techniques such as cryoneuroablation and radiofrequency denervation are available. Because of the location, complications from injections can be serious, and so the injections must be performed with care and knowledge of the anatomy.","PeriodicalId":87440,"journal":{"name":"Journal of neuropathic pain & symptom palliation","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72633222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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