Nestle Nutrition workshop series. Paediatric programme最新文献_第4页

How proteins improve the development of preterm infants. 蛋白质如何促进早产儿的发育。

Nestle Nutrition workshop series. Paediatric programme Pub Date : 2011-01-01 Epub Date: 2011-10-03 DOI: 10.1159/000325658

W E Corpeleijn, C H van den Akker, J A Roelants, J B van Goudoever

引用次数: 4

Milk and the risk and progression of cancer. 牛奶与癌症的风险和发展之间的关系。

Nestle Nutrition workshop series. Paediatric programme Pub Date : 2011-01-01 Epub Date: 2011-02-16 DOI: 10.1159/000325583

Cheryl L Rock

{"title":"Milk and the risk and progression of cancer.","authors":"Cheryl L Rock","doi":"10.1159/000325583","DOIUrl":"https://doi.org/10.1159/000325583","url":null,"abstract":"Observational evidence suggests that nutritional factors contribute to a substantial proportion of cancer cases, and milk contains numerous bioactive substances that could affect risk and progression of cancer. Cancer results from multiple genetic and epigenetic events over time, so demonstrating a specific effect of nutrients or other bioactive food components in human cancer is challenging. Epidemiological evidence consistently suggests that milk intake is protective against colorectal cancer. Calcium supplements have been shown to reduce risk for recurrence of adenomatous polyps. Calcium supplementation has not been observed to reduce risk for colon cancer, although long latency and baseline calcium intake affect interpretation of these results. High calcium intake from both food and supplements is associated with increased risk for advanced or fatal prostate cancer. Results from epidemiological studies examining the relationship between intake of dairy foods and breast or ovarian cancer risk are not consistent. Animal studies have suggested that galactose may be toxic to ovarian cells, but results from epidemiological studies that have examined ovarian cancer risk and milk and/or lactose intakes are mixed. Dietary guidelines for cancer prevention encourage meeting recommended levels of calcium intake primarily through food choices rather than supplements, and choosing low-fat or nonfat dairy foods.","PeriodicalId":87412,"journal":{"name":"Nestle Nutrition workshop series. Paediatric programme","volume":"67 ","pages":"173-85"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000325583","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29684315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Milk and oral health. 牛奶与口腔健康。

Nestle Nutrition workshop series. Paediatric programme Pub Date : 2011-01-01 Epub Date: 2011-02-16 DOI: 10.1159/000325575

Ingegerd Johansson, Pernilla Lif Holgerson

{"title":"Milk and oral health.","authors":"Ingegerd Johansson, Pernilla Lif Holgerson","doi":"10.1159/000325575","DOIUrl":"https://doi.org/10.1159/000325575","url":null,"abstract":"Oral health includes freedom from disease in the gums, the mucosa and the teeth. There has been a striking reduction in dental caries and periodontitis in industrialized countries, although the proportion with severe disease has remained at 10-15%, and the prevalence increases in less developed countries. If left untreated, these diseases may lead to pain, and impaired quality of life and nutritional status. Prevention and treatment need, besides traditional implementation of proper oral hygiene, sugar restriction and use of fluoride, newer cost-effective strategies. Non-sweetened dairy products, which are proven non-cariogenic, or specific bioactive components from alike sources might prove to be part of such strategies. Thus, milk proteins, such as bovine and human caseins and lactoferrin, inhibit initial attachment of cariogenic mutans streptococci to hydroxyapatite coated with saliva or purified saliva host ligands. In contrast, both bovine and human milk coated on hydroxyapatite promotes attachment of commensal Actinomyces naeslundii and other streptococci in vitro, and phosphorylated milk-derived peptides promote maintenance of tooth minerals, as shown for the β-casein-derived caseino-phosphate peptide. Observational studies are promising, but randomized clinical trials are needed to reveal if dairy products could be a complementary treatment for oral health.","PeriodicalId":87412,"journal":{"name":"Nestle Nutrition workshop series. Paediatric programme","volume":"67 ","pages":"55-66"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000325575","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29684395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Developing world perspective: the importance of growth for short-term health. 发展中国家的观点:增长对短期健康的重要性。

Nestle Nutrition workshop series. Paediatric programme Pub Date : 2010-01-01 Epub Date: 2010-02-01 DOI: 10.1159/000281146

Linda S Adair

{"title":"Developing world perspective: the importance of growth for short-term health.","authors":"Linda S Adair","doi":"10.1159/000281146","DOIUrl":"https://doi.org/10.1159/000281146","url":null,"abstract":"Recently, concern has been raised about the potential adverse long-term consequences of rapid child growth. Rapid early childhood weight gain is associated with increased likelihood of being overweight or obese later in childhood and of having risk factors for the development of chronic disease such insulin resistance and elevated blood pressure. This has led to concerns about the wisdom of promoting catch-up growth in infants born small for gestational age or in children with poor growth after birth. In considering the costs and benefits of promoting catch-up growth, we must not lose sight of the immediate health threats to children in resource-poor environments in developing countries where child morbidity and mortality remain high. The literature on short-term consequences of growth is limited by its focus on attained size as an indicator of prior nutritional status, but generally shows that children with evidence of poor prior growth are at greater risk of morbidity and mortality from common infectious diseases, including lower respiratory infections and diarrhea. In these settings, failure to promote compensatory growth may have devastating short-term consequences.","PeriodicalId":87412,"journal":{"name":"Nestle Nutrition workshop series. Paediatric programme","volume":"65 ","pages":"71-9; discussion 79-83"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000281146","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28699871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Role of long-chain polyunsaturated fatty acids in neurodevelopment and growth. 长链多不饱和脂肪酸在神经发育和生长中的作用。

Nestle Nutrition workshop series. Paediatric programme Pub Date : 2010-01-01 Epub Date: 2010-02-01 DOI: 10.1159/000281154

Maria Makrides, Lisa G Smithers, Robert A Gibson

{"title":"Role of long-chain polyunsaturated fatty acids in neurodevelopment and growth.","authors":"Maria Makrides, Lisa G Smithers, Robert A Gibson","doi":"10.1159/000281154","DOIUrl":"https://doi.org/10.1159/000281154","url":null,"abstract":"There has been intense interest in the role of the n-3 long-chain polyunsaturated fatty acid (LCPUFA) docosahexaenoic acid (DHA, 22:6n-3), in growth and development of infants. In 2009, there are at least twelve published randomized controlled trials (RCT) assessing the effects of LCPUFA supplementation of infant formula for preterm infants and seventeen RCTs involving formula-fed term infants. In addition, at least five RCTs have investigated the effect of DHA supplementation during pregnancy and/or lactation on infant and early child development. Collectively, the published literature has demonstrated no harm of dietary LCPUFA for infants regardless of whether they are born preterm or at term. However, developmental benefit is more consistently observed in infants born preterm. This may be explained by the fact that DHA accretion to neural tissues peaks during the fetal brain growth spurt in the last trimester of pregnancy. Infants born preterm are denied the full gestation period to accumulate DHA and are at risk of incomplete DHA accumulation. New research is focused on the timing and dose of DHA supplementation needed to optimize developmental outcomes.","PeriodicalId":87412,"journal":{"name":"Nestle Nutrition workshop series. Paediatric programme","volume":"65 ","pages":"123-33; discussion 133-6"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000281154","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28699874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 60

The 2000 Centers for Disease Control and Prevention growth charts: several insights after 8 years. 2000年疾病控制和预防中心的增长图表:8年后的几点见解。

Nestle Nutrition workshop series. Paediatric programme Pub Date : 2010-01-01 Epub Date: 2010-02-01 DOI: 10.1159/000281163

Cynthia L Ogden, Rong Wei, Lester R Curtin, Katherine M Flegal

{"title":"The 2000 Centers for Disease Control and Prevention growth charts: several insights after 8 years.","authors":"Cynthia L Ogden, Rong Wei, Lester R Curtin, Katherine M Flegal","doi":"10.1159/000281163","DOIUrl":"https://doi.org/10.1159/000281163","url":null,"abstract":"This paper explores three issues related to the 2000 Centers for Disease Control and Prevention growth charts. First, it clarifies the methods that were used to create the charts as it has become apparent that the smoothing techniques have been somewhat misunderstood. The techniques included smoothing-selected percentiles between and including the 3rd and 97th percentiles and then approximating these smoothed curves using a procedure to provide the transformation parameters, lambda, mu, and sigma. Only the selected percentiles were used in this process due to small sample sizes beyond these percentiles. Second, given the concern that the infant charts were created with relatively few data points in the first few months of life, it compares the original observed percentiles with percentiles that include newly available US national data for the first few months of life. Third, it discusses the issues that arise if a 99th percentile is extrapolated based on the lambda, mu, and sigma parameters. The 99th percentile of the body mass index-for-age chart has been recommended to identify extremely obese children, yet the 97th percentile is the highest available percentile on the Centers for Disease Control and Prevention growth charts.","PeriodicalId":87412,"journal":{"name":"Nestle Nutrition workshop series. Paediatric programme","volume":"65 ","pages":"181-93; discussion 193-5"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000281163","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28699808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Novel insights into human lactation as a driver of infant formula development. 人类哺乳作为婴儿配方奶粉开发驱动程序的新见解。

Nestle Nutrition workshop series. Paediatric programme Pub Date : 2010-01-01 Epub Date: 2010-07-21 DOI: 10.1159/000318945

Bo Lönnerdal

{"title":"Novel insights into human lactation as a driver of infant formula development.","authors":"Bo Lönnerdal","doi":"10.1159/000318945","DOIUrl":"https://doi.org/10.1159/000318945","url":null,"abstract":"Progress in research on human lactation and breast milk has advanced our knowledge about the significance of breast milk for the recipient infant and the effects of various components on long-term outcomes. Recent findings have expanded our knowledge in this area. Several growth factors and cytokines are present in breast milk and their capacity to persist in the infant gut and exert their activities is likely to affect maturation of immune function, possibly affecting the development of oral tolerance. A proper balance of polyunsaturated fatty acids (n-3/n-6 ratio) may also be of significance for allergy prevention in children, emphasizing the need for the mother to achieve a balance of these fatty acids in her diet. The recent findings that specific strains of bacteria are present in breast milk and act as probiotics in the early colonization of the infant gut and that human milk oligosaccharides are specific substrates for these probiotic strains may not only affect the defense against pathogens, but also affect energy utilization and development of obesity. Previously neglected milk fat globule membranes contain several components involved in protection against infection and may be an additional arm in the multifaceted shield that breastfed infants have developed against bacterial and viral antagonists. All these findings have implications for development of improved infant formulae.","PeriodicalId":87412,"journal":{"name":"Nestle Nutrition workshop series. Paediatric programme","volume":"66 ","pages":"19-29"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000318945","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29152700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Technological progress as a driver of innovation in infant foods. 技术进步是婴儿食品创新的驱动力。

Nestle Nutrition workshop series. Paediatric programme Pub Date : 2010-01-01 Epub Date: 2010-07-21 DOI: 10.1159/000318950

Mario G Ferruzzi, Andrew P Neilson

{"title":"Technological progress as a driver of innovation in infant foods.","authors":"Mario G Ferruzzi, Andrew P Neilson","doi":"10.1159/000318950","DOIUrl":"https://doi.org/10.1159/000318950","url":null,"abstract":"Advances in nutrition and food sciences are interrelated components of the innovative framework for infant formula and foods. While nutrition science continues to define the composition and functionality of human milk as a reference, food ingredient, formulation and processing technologies facilitate the design and delivery of nutritional and functional concepts to infant products. Expanding knowledge of both nutritive and non-nutritive components of human milk and their functionality guides selection and development of novel ingredient, formulation and processing methods to generate enhanced infant products targeting benefits including healthy growth, development as well as protection of health through the life cycle. In this chapter, identification and application of select novel ingredients/technologies will be discussed in the context of how these technological advancements have stimulated innovation in infant foods. Special focus will be given to advancements in protein technologies, as well as bioactive long-chain polyunsaturated fatty acids, prebiotics, probiotics that have allowed infant formula composition, and more critically functionality, to more closely align with that of human milk.","PeriodicalId":87412,"journal":{"name":"Nestle Nutrition workshop series. Paediatric programme","volume":"66 ","pages":"81-95"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000318950","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29151132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Progress of enteral feeding practice over time: moving from energy supply to patient- and disease-adapted formulations. 肠内喂养实践的进展:从能量供应到适应病人和疾病的配方。

Nestle Nutrition workshop series. Paediatric programme Pub Date : 2010-01-01 Epub Date: 2010-07-21 DOI: 10.1159/000318947

Sibylle Koletzko

{"title":"Progress of enteral feeding practice over time: moving from energy supply to patient- and disease-adapted formulations.","authors":"Sibylle Koletzko","doi":"10.1159/000318947","DOIUrl":"https://doi.org/10.1159/000318947","url":null,"abstract":"Enteral nutrition comprises the delivery of a liquid formula beyond the esophagus via a feeding tube in a patient with insufficient oral intake, as well as the provision of specialized nutritional formula irrespective of the route of delivery. Pediatric formulae have been designed for different age groups, and for children with certain diseases; examples are special formulations for regurgitating infants, metabolic diseases, cow's milk or multiple food allergies, intestinal, pancreatic, renal, and hepatic insufficiency. Exclusive enteral nutrition is a therapeutic concept to induce remission in children and adolescents with active Crohn's disease. A new area of nutritional research in pediatrics is potential immunonutrition in critically ill children. Formulae are enriched with single components or a combination of key substrates that might play a crucial role during intermediary metabolism in sepsis, inflammation, tissue healing, and growth. For pharmaconutrition, single components are investigated in a scientific stepwise procedure in order to identify effective disease-dedicated nutrition therapy. Any new formula needs to be evaluated, if possible in comparison to a normal diet or the reference formulation to demonstrate its safety and efficacy (equal or superior to standard formula).","PeriodicalId":87412,"journal":{"name":"Nestle Nutrition workshop series. Paediatric programme","volume":"66 ","pages":"41-54"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000318947","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29151129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Early infancy as a critical period for development of obesity and related conditions. 婴儿期早期是肥胖症及相关疾病发展的关键时期。

Nestle Nutrition workshop series. Paediatric programme Pub Date : 2010-01-01 Epub Date: 2010-02-01 DOI: 10.1159/000281141

Matthew W Gillman

引用次数: 0