Oncology & hematology review最新文献

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Evolving Therapies for Urothelial Carcinoma—Novel Paradigms and Future Directions 尿路上皮癌的新疗法和未来发展方向
Oncology & hematology review Pub Date : 2021-01-01 DOI: 10.17925/OHR.2021.16.2.82
Madison H. Williams, Ryan M. Williams, D. Mahadevan, C. Ramamurthy
{"title":"Evolving Therapies for Urothelial Carcinoma—Novel Paradigms and Future Directions","authors":"Madison H. Williams, Ryan M. Williams, D. Mahadevan, C. Ramamurthy","doi":"10.17925/OHR.2021.16.2.82","DOIUrl":"https://doi.org/10.17925/OHR.2021.16.2.82","url":null,"abstract":"<p />","PeriodicalId":87332,"journal":{"name":"Oncology & hematology review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67597716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pexidartinib and CSF1R Inhibitors as Treatment for Tenosynovial Giant Cell Tumors 培西达替尼和CSF1R抑制剂治疗腱鞘巨细胞瘤
Oncology & hematology review Pub Date : 2021-01-01 DOI: 10.17925/OHR.2021.16.2.119
C. Granger, T. Subhawong, G. D'Amato, Emily E. Jonczak, Erika L. Garbrecht, S. Conway, J. Trent
{"title":"Pexidartinib and CSF1R Inhibitors as Treatment for Tenosynovial Giant Cell Tumors","authors":"C. Granger, T. Subhawong, G. D'Amato, Emily E. Jonczak, Erika L. Garbrecht, S. Conway, J. Trent","doi":"10.17925/OHR.2021.16.2.119","DOIUrl":"https://doi.org/10.17925/OHR.2021.16.2.119","url":null,"abstract":"<p />","PeriodicalId":87332,"journal":{"name":"Oncology & hematology review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67598171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Evolving Role of Radiotherapy in Locally Advanced Rectal Cancer and the Potential for Nonoperative Management. 放射治疗在局部晚期直肠癌中的作用及其非手术治疗的潜力。
Oncology & hematology review Pub Date : 2020-01-01 Epub Date: 2020-04-27
Karishma Khullar, Nell Maloney Patel, Cristan Anderson, Anupama Chundury, Darren Carpizo, Daniel Feingold, Miral Grandhi, Howard Hochster, Krupa Jani, Timothy Kennedy, Russell Langan, Kristen Spencer, David August, Salma K Jabbour
{"title":"The Evolving Role of Radiotherapy in Locally Advanced Rectal Cancer and the Potential for Nonoperative Management.","authors":"Karishma Khullar,&nbsp;Nell Maloney Patel,&nbsp;Cristan Anderson,&nbsp;Anupama Chundury,&nbsp;Darren Carpizo,&nbsp;Daniel Feingold,&nbsp;Miral Grandhi,&nbsp;Howard Hochster,&nbsp;Krupa Jani,&nbsp;Timothy Kennedy,&nbsp;Russell Langan,&nbsp;Kristen Spencer,&nbsp;David August,&nbsp;Salma K Jabbour","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Locally advanced rectal cancer has broadly been defined as T3, T4, or lymph node-positive disease. In the 1990s, adjuvant chemoradiation was considered the optimal management for locally advanced rectal cancer. However, the paradigm shifted when the German CAO/ARO/AIO-94 Rectal Cancer trial established neoadjuvant chemoradiation as the standard of care, based on reduced rates of toxicity and local recurrence, as well as higher rates of sphincter preservation compared with postoperative chemoradiation. Both short-course radiation and long-course chemoradiation are currently accepted methods for neoadjuvant treatment, with recent trials showing equivalence in outcomes. While surgery remains the cornerstone of treatment, there are data supporting the use of magnetic resonance imaging for risk stratification in rectal cancer and encouraging prospective data regarding nonoperative management. This review summarizes data on the evolution of treatment for locally advanced rectal cancer and discusses emerging evidence for nonoperative management.</p>","PeriodicalId":87332,"journal":{"name":"Oncology & hematology review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439775/pdf/nihms-1589985.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38300648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endocrine Therapy-related Endocrinopathies-Biology, Prevalence and Implications for the Management of Breast Cancer. 内分泌治疗相关的内分泌病变-生物学,患病率和对乳腺癌管理的影响。
Oncology & hematology review Pub Date : 2020-01-01 Epub Date: 2020-02-16 DOI: 10.17925/ohr.2020.16.1.17
Kristy A Brown, Eleni Andreopoulou, Panagiota Andreopoulou
{"title":"Endocrine Therapy-related Endocrinopathies-Biology, Prevalence and Implications for the Management of Breast Cancer.","authors":"Kristy A Brown,&nbsp;Eleni Andreopoulou,&nbsp;Panagiota Andreopoulou","doi":"10.17925/ohr.2020.16.1.17","DOIUrl":"https://doi.org/10.17925/ohr.2020.16.1.17","url":null,"abstract":"<p><p>Nearly 270,000 new breast cancer cases are predicted to be diagnosed in the USA in 2019 with more than 70% being estrogen receptor positive and treated using endocrine therapy. The suppression of estrogen biosynthesis or action via the use of ovarian suppression, aromatase inhibitors and selective estrogen receptor modulators/degraders, respectively, is effective in approximately 70% of women. The systemic inhibition of estrogen during breast cancer treatment is also associated with side effects due to the important endocrine functions of this steroid hormone, including its role in the maintenance of energy homeostasis and bone health. The current work will present perspectives of the impact of endocrine therapy from the point of view of breast medical oncology, endocrinology, and basic science.</p>","PeriodicalId":87332,"journal":{"name":"Oncology & hematology review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034602/pdf/nihms-1673368.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25590707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Hypothermic Intraperitoneal Chemotherapy for Gastrointestinal Malignancies—A Relic of the Past or Useful Tool for Today? 腹腔低温化疗治疗胃肠道恶性肿瘤——是过去的遗物还是今天的有用工具?
Oncology & hematology review Pub Date : 2019-01-01 DOI: 10.17925/ohr.2019.15.2.83
M. Greally, D. Ilson
{"title":"Hypothermic Intraperitoneal Chemotherapy for Gastrointestinal Malignancies—A Relic of the Past or Useful Tool for Today?","authors":"M. Greally, D. Ilson","doi":"10.17925/ohr.2019.15.2.83","DOIUrl":"https://doi.org/10.17925/ohr.2019.15.2.83","url":null,"abstract":"<p />","PeriodicalId":87332,"journal":{"name":"Oncology & hematology review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67597253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neoantigen Vaccine Delivery for Personalized Anticancer Immunotherapy—the PSV™ Platform 用于个性化抗癌免疫治疗的新抗原疫苗递送- PSV™平台
Oncology & hematology review Pub Date : 2019-01-01 DOI: 10.17925/ohr.2019.15.2.64
Paisley T. Myers, Lexington Ma Usa Agenus
{"title":"Neoantigen Vaccine Delivery for Personalized Anticancer Immunotherapy—the PSV™ Platform","authors":"Paisley T. Myers, Lexington Ma Usa Agenus","doi":"10.17925/ohr.2019.15.2.64","DOIUrl":"https://doi.org/10.17925/ohr.2019.15.2.64","url":null,"abstract":"<p />","PeriodicalId":87332,"journal":{"name":"Oncology & hematology review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67597559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding Survival Disparities in Gastric Cancer 了解胃癌的生存差异
Oncology & hematology review Pub Date : 2019-01-01 DOI: 10.17925/ohr.2019.15.2.78
Julie La, S. Merchant
{"title":"Understanding Survival Disparities in Gastric Cancer","authors":"Julie La, S. Merchant","doi":"10.17925/ohr.2019.15.2.78","DOIUrl":"https://doi.org/10.17925/ohr.2019.15.2.78","url":null,"abstract":"<p />","PeriodicalId":87332,"journal":{"name":"Oncology & hematology review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67597698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Updates in Lung Cancer 2018—What the Pulmonologist Needs to Know 2018年肺癌最新进展——肺科医生需要知道的事情
Oncology & hematology review Pub Date : 2019-01-01 DOI: 10.17925/OHR.2019.15.1.20
M. Rivera
{"title":"Updates in Lung Cancer 2018—What the Pulmonologist Needs to Know","authors":"M. Rivera","doi":"10.17925/OHR.2019.15.1.20","DOIUrl":"https://doi.org/10.17925/OHR.2019.15.1.20","url":null,"abstract":"<p />","PeriodicalId":87332,"journal":{"name":"Oncology & hematology review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67597239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in the Treatment of Endometrial and Ovarian Cancer 子宫内膜癌和卵巢癌的治疗进展
Oncology & hematology review Pub Date : 2019-01-01 DOI: 10.17925/OHR.2019.15.1.23
D. Mutch
{"title":"Advances in the Treatment of Endometrial and Ovarian Cancer","authors":"D. Mutch","doi":"10.17925/OHR.2019.15.1.23","DOIUrl":"https://doi.org/10.17925/OHR.2019.15.1.23","url":null,"abstract":"<p />","PeriodicalId":87332,"journal":{"name":"Oncology & hematology review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67597302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current Therapeutic Options in Waldenström Macroglobulinemia Waldenström巨球蛋白血症的当前治疗方案
Oncology & hematology review Pub Date : 2019-01-01 DOI: 10.17925/OHR.2019.15.1.39
S. Zanwar, J. Abeykoon, P. Kapoor
{"title":"Current Therapeutic Options in Waldenström Macroglobulinemia","authors":"S. Zanwar, J. Abeykoon, P. Kapoor","doi":"10.17925/OHR.2019.15.1.39","DOIUrl":"https://doi.org/10.17925/OHR.2019.15.1.39","url":null,"abstract":"<p />","PeriodicalId":87332,"journal":{"name":"Oncology & hematology review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67597462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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