{"title":"PubMed at its best. Useful skills to perform an effective search, save it and automatically receive updates.","authors":"E Giglia","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87180,"journal":{"name":"Europa medicophysica","volume":"43 3","pages":"427-37"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27036898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MEG mapping in multiple sclerosis patients.","authors":"A Kotini, P Anninos, D Tamiolakis","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aim: </strong>The research over the past decade suggests that multiple sclerosis (MS) is a disease due to disorders of the immune system. Since the immune system is regulated by the pineal gland, which exerts immunomodulatory action with the secretion of melatonin and profound effects on electrical activity in the hippocampus, cerebellum and reticular formation structures, we have used magnetoencephalogram (MEG) recordings from MS patients in order to find any differentiation in brain activity in comparison with controls.</p><p><strong>Methods: </strong>Ten MS patients and 10 controls were included in this study. The measurements were performed with a superconducting quantum interference device (SQUID) in an electrically shielded room. For each patient the magnetic activity was recorded from a total of 32 points of the skull as defined by a recording reference system, which is based on the International 10-20 Electrode Placement System.</p><p><strong>Results: </strong>The biomagnetic signals (waveforms) were expressed in terms of magnetic power spectral amplitudes in the frequency range of 2-7 Hz. Some of the recorded points were observed to exhibit abnormal rhythmic activity, characterized by lower amplitudes and frequencies compared with controls. Using the MEG brain activity we were able to obtain a mapping technique characterized by the ISO-spectral amplitude of scalp distribution.</p><p><strong>Conclusion: </strong>This study, although preliminary, presents a novel approach for measuring brain biomagnetic activity from MS patients.</p>","PeriodicalId":87180,"journal":{"name":"Europa medicophysica","volume":"43 3","pages":"345-8"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26621583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Karsidag, S Sahin, S Hacikerim Karsidag, S Ayalp
{"title":"Long term and frequent electrophysiological observation in carpal tunnel syndrome.","authors":"S Karsidag, S Sahin, S Hacikerim Karsidag, S Ayalp","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aim: </strong>Carpal tunnel syndrome (CTS) is one of the most common compression neuropathies in neurology. Electromyography (EMG) including nerve conduction study (NCS) is the most useful diagnostic technique for CTS. In this study, we aim to demonstrate changes in electrophysiological parameters in different level of CTS patients by frequent EMG studies.</p><p><strong>Methods: </strong>We prospectively followed patients with CTS regularly once every 12 weeks for 1 year. Fourteen women (28 hands) with EMG/NCS findings of CTS were observed and classified in 3 groups according to electrophysiological severity. All patients were instructed to wear the splint for 12 weeks. At the end of this period, patients were evaluated by electrophysiologic parameters. If findings were still abnormal, they were encouraged to continue wearing the splint. In severe cases, surgical release was carried out.</p><p><strong>Results: </strong>No statistically significant changes were noted in EMG recordings of mild cases repeated every 3 months. It was determined that significant improvements begin to occur in the moderate group in all parameters, except for the amplitude of the median sensory nerve. However, when the mean values were studied in the severe CTS group, it was observed that the preoperative motor and sensory parameters became increasingly impaired, but approached the initial values in the first evaluation in the postoperative period.</p><p><strong>Conclusion: </strong>Subjects with CTS, particularly moderate as determined by electrophysiology, may benefit from conservative therapy, with improvements which continue for about one year. In severe cases the main treatment modality seems to be operation. Frequent electrophysiological follow-ups may be useful in guiding treatment.</p>","PeriodicalId":87180,"journal":{"name":"Europa medicophysica","volume":"43 3","pages":"327-32"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26742970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Di Lorenzo, A Forte, R Formisano, R Gimigliano, S Gatto
{"title":"Low back pain after unstable extracapsular hip fractures: randomized control trial on a specific training.","authors":"L Di Lorenzo, A Forte, R Formisano, R Gimigliano, S Gatto","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aim: </strong>This study compares the efficacy of a walking recovery rehabilitation program with or without specific back exercises in patients affected by unstable extracapsular hip fractures and secondary back pain. Further, it reports data and images about analysed tomographic changes of the psoas muscle ipsilateral to fractures.</p><p><strong>Methods: </strong>A prospective, randomized, parallel treatment trial was carried out. Patients admitted for rehabilitation after fractures were evaluated for secondary back pain. If clinically indicated, patients were further scheduled for a computed tomography (CT) scan of the lumbar spine by which we evaluated cross-sectional changes in density and fibroadipose degeneration of the body of the psoas muscle. When back pain matched cross-sectional changes in psoas density, the patient was eligible for our study, enrolled and randomly assigned to 1 of 2 study groups. Both groups were scheduled for hip rehabilitation and walking training plus a back protocol for the study group only. Pain was evaluated subjectively with a visual analog scale to calculate treatment effectiveness and Harris hip score was used to assess the outcome after surgery.</p><p><strong>Results: </strong>Thirty-seven patients out of about hundred were enrolled. In all cases CT scans showed age-related changes commonly seen in the lumbar spine and significant fibroadipose degeneration and altered density in the ipsilateral psoas muscles. With back exercises added to the standard rehabilitation protocol, all study patients recovered significantly better than control group patients (P<0.04) in only 4 weeks of treatment.</p><p><strong>Conclusion: </strong>Results show how hip fractures may cause psoas changes that can be of relevance for a more rational choice of physical exercises. Causes of back pain may be more complex than described by the textbooks and prognosis is more favourable following specific back training.</p>","PeriodicalId":87180,"journal":{"name":"Europa medicophysica","volume":"43 3","pages":"349-57"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26800129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neuroimaging: a new challenge in neurorehabilitation of stroke patients.","authors":"D Bonaiuti, M Grimaldi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87180,"journal":{"name":"Europa medicophysica","volume":"43 2","pages":"215-9"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26794110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P M Rossini, C Altamura, F Ferreri, J-M Melgari, F Tecchio, M Tombini, P Pasqualetti, F Vernieri
{"title":"Neuroimaging experimental studies on brain plasticity in recovery from stroke.","authors":"P M Rossini, C Altamura, F Ferreri, J-M Melgari, F Tecchio, M Tombini, P Pasqualetti, F Vernieri","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Topographical cortical organization of sensorimotor area has been shown to be highly plastic, altering his configuration in response to training in different tasks in healthy controls and neurological patients. The term ''brain plasticity'' encompasses all possible mechanisms of neuronal reorganization: recruitment of pathways that are functionally homologous to, but anatomically distinct from, the damaged ones (eg, non-pyramidal corticospinal pathways), synaptogenesis, dendritic arborisation and reinforcement of existing but functionally silent synaptic connections (particularly at the periphery of core lesion). The study of neuroplasticity has clearly shown the ability of the developing brain--and of the adult and ageing brain--to be shaped by environmental inputs both under normal conditions (ie, learning) and after a lesion. Neuronal aggregates adjacent, or distant to a lesion in the sensorimotor area can progressively adopt the function of the injured area. Imaging studies indicate that recovery of motor function after a lesion (i.e. stroke) is associated with a progressive change of activation patterns in specific brain structures. Transcranial magnetic stimulation (TMS) and magnetoencephalography (MEG) can detect reshaping of sensorimotor areas; they have a high temporal resolution but have several limitations. TMS can only provide bidimensional scalp maps and MEG depicts three-dimensional spatial characteristics of virtual neural generators obtained by use of a mathematical model of the head and brain. However, the use of objective methods that assess brain reactivity to a physical stimulus (i.e., TMS) or to a sensory input (ie, electrical stimulation to hand and fingers) can integrate information from self-paced motor tasks, because the resolution of abnormal activation over time could be secondary to recovery. Functional MRI (fMRI) and positron emission tomography (PET), on their own, have insufficient time resolution to follow the hierarchical activation of relays within a neural network; however, because of their excellent spatial resolution, they can integrate the findings of TMS and MEG. An integrated approach constitutes, at present, the best way to assess the brain plasticity both under normal conditions and after a lesion.</p>","PeriodicalId":87180,"journal":{"name":"Europa medicophysica","volume":"43 2","pages":"241-54"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26794111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Europa Medicophysica and its ''free full text'' in Internet: toward the first open access of a general rehabilitation journal.","authors":"S Negrini","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87180,"journal":{"name":"Europa medicophysica","volume":"43 2","pages":"135-7"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26794107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Continuing medical education and continuing professional development in the Mediterranean countries.","authors":"N Christodoulou","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87180,"journal":{"name":"Europa medicophysica","volume":"43 2","pages":"195-202"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26794108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diffusion and perfusion-weighted magnetic resonance imaging techniques in stroke recovery.","authors":"H J Aronen, M P Laakso, M Moser, J Perkiö","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Most of the functional recovery after stroke takes place during the first three months after the insult. The neuronal mechanisms underlying this recovery are presently mostly unknown. However, in order to create efficient rehabilitation programs, it is of great importance to uncover these mechanisms. Multiple imaging techniques have been employed for the detection and characterization of ischemic lesions in the brain as well as monitoring of processes associated with stroke recovery. Diffusion and perfusion-weighted magnetic resonance imaging techniques are easy and fast to perform and provide significant information about the ischemic lesion and the hypoperfusion surrounding the lesion at both micro and macrovascular level. More sensitive detection and accurate characterization of the lesion will help in choosing the therapeutic strategies. Methods for monitoring brain function recovery will provide a better understanding of the basic mechanisms of plasticity in the brain, and will serve as a tool for the evaluation of therapeutic interventions, which may eventually include, for example, stem cell transplantation. With the help of these diagnostic tools it may become possible to tailor individual rehabilitation programs.</p>","PeriodicalId":87180,"journal":{"name":"Europa medicophysica","volume":"43 2","pages":"271-84"},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26794113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}