Acta orthopaedica. Supplementum最新文献_第3页

Acrylic bone cements: influence of time and environment on physical properties. 丙烯酸骨水泥:时间和环境对物理性能的影响。

Acta orthopaedica. Supplementum Pub Date : 2010-06-01 DOI: 10.3109/17453674.2010.487929

Markus Nottrott

{"title":"Acrylic bone cements: influence of time and environment on physical properties.","authors":"Markus Nottrott","doi":"10.3109/17453674.2010.487929","DOIUrl":"https://doi.org/10.3109/17453674.2010.487929","url":null,"abstract":"Acrylic bone cements are in extensive use in joint replacement surgery. They are weight bearing and load transferring in the bone-cement-prosthesis complex and therefore, inter alia, their mechanical properties are deemed to be crucial for the overall outcome. In spite of adequate preclinical test results according to the current specifications (ISO, ASTM), cements with inferior clinical results have appeared on the market. The aim of this study was to investigate whether it is possible to predict the long term clinical performance of acrylic bone cement on the basis of mechanical in vitro testing. We performed in vitro quasistatic testing of cement after aging in different media and at different temperatures for up to 5 years. Dynamic creep testing and testing of retrieved cement were also performed. Testing under dry conditions, as required in current standards, always gave higher values for mechanical properties than did storage and testing under more physiological conditions. We could demonstrate a continuous increase in mechanical properties when testing in air, while testing in water resulted in a slight decrease in mechanical properties after 1 week and then levelled out. Palacos bone cement showed a higher creep than CMW3G and the retrieved Boneloc specimens showed a higher creep than retrieved Palacos. The strength of a bone cement develops more slowly than the apparent high initial setting rate indicates and there are changes in mechanical properties over a period of five years. The effect of water absorption is important for the physical properties but the mechanical changes caused by physical aging are still present after immersion in water. The established standards are in need of more clinically relevant test methods and their associated requirements need better definition. We recommend that testing of bone cements should be performed after extended aging under simulated physiological conditions. Simple quasistatic and dynamic creep tests seem unable to predict clinical performance of acrylic bone cements when the products under test are chemically very similar. However, such testing might be clinically relevant if the cements exhibit substantial differences.","PeriodicalId":87168,"journal":{"name":"Acta orthopaedica. Supplementum","volume":"81 341","pages":"1-27"},"PeriodicalIF":0.0,"publicationDate":"2010-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/17453674.2010.487929","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29003489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

Microarchitectural adaptations in aging and osteoarthrotic subchondral bone issues. 衰老和骨关节软骨下骨问题的微结构适应。

Acta orthopaedica. Supplementum Pub Date : 2010-02-01 DOI: 10.3109/17453671003619037

Ming Ding

{"title":"Microarchitectural adaptations in aging and osteoarthrotic subchondral bone issues.","authors":"Ming Ding","doi":"10.3109/17453671003619037","DOIUrl":"https://doi.org/10.3109/17453671003619037","url":null,"abstract":"The human skeleton optimizes its microarchitecture by elaborate adaptations to mechanical loading during development and growth. The mechanisms for adaptation involve a multistep process of cellular mechanotransduction stimulating bone modelling, and remodeling resulting in either bone formation or resorption. This process causes appropriate microarchitectural changes tending to adjust and improve the bone structure to its prevailing mechanical environment. Normal individual reaches peak bone mass at age between 25 and 30 years, and thereafter bone mass declines with age in both genders. The bone loss is accompanied by microarchitectural deterioration resulting in reduced mechanical strength likely leading to fragility fractures. With aging, inevitable bone loss occurs, which is frequently the cause of osteoporosis; and inevitable bone and joint degeneration happens, which often results in osteoarthrosis. These diseases are among the major health care problems in terms of socio-economic costs. The overall goals of the current series of studies were to investigate the age-related and osteoarthrosis (OA) related changes in the 3-D microarchitectural properties, mechanical properties, collagen and mineral quality of subchondral cancellous and cortical bone tissues. The studies included mainly two parts. For human subjects: aging- (I–IV) and early OArelated (V–VI) changes in cancellous bone properties were assessed. For OA guinea pig models (VII–IX), three topics were studied: firstly, the spontaneous, age-related development of guinea pig OA; secondly, the potential effects of hyaluronan on OA subchondral bone tissues; and thirdly, the effects on OA progression of an increase in subchondral bone density by inhibition of bone remodeling with a bisphosphonate. These investigations aimed to obtain more insight into the age-related and OA-related subchondral bone adaptations.","PeriodicalId":87168,"journal":{"name":"Acta orthopaedica. Supplementum","volume":"81 340","pages":"1-53"},"PeriodicalIF":0.0,"publicationDate":"2010-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/17453671003619037","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29495950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 48

Congenital clubfoot. Aspects on epidemiology, residual deformity and patient reported outcome. 先天性畸形足。流行病学方面，残畸形和患者报告的结果。

Acta orthopaedica. Supplementum Pub Date : 2010-02-01 DOI: 10.3109/17453671003619045

Henrik M Wallander

引用次数: 15

Use of medications and risk of revision after primary total hip arthroplasty. 初次全髋关节置换术后药物的使用和翻修的风险。

Acta orthopaedica. Supplementum Pub Date : 2009-12-01 DOI: 10.3109/17453670903448240

Theis Muncholm Thillemann

引用次数: 5

Polyethylene wear analysis. 聚乙烯磨损分析。

Acta orthopaedica. Supplementum Pub Date : 2009-10-01 DOI: 10.3109/17453670903420819

Maiken Stilling

引用次数: 9

Evolution of the hip and pelvis. 髋关节和骨盆的进化。

Acta orthopaedica. Supplementum Pub Date : 2009-08-01 DOI: 10.1080/17453690610046620

Tom Hogervorst, Heinse W Bouma, John de Vos

引用次数: 60

On the diagnosis and treatment of femoral neck fractures. 股骨颈骨折的诊断与治疗。

Acta orthopaedica. Supplementum Pub Date : 2009-06-01 DOI: 10.1080/17453690610046611

Frede Frihagen

引用次数: 5

The Scandinavian Sarcoma Group: 30 years' experience. 斯堪的纳维亚肉瘤集团:30年的经验。

Acta orthopaedica. Supplementum Pub Date : 2009-04-01 DOI: 10.1080/17453690610046602

Thor Alvegård, Kirsten Sundby Hall, Henrik Bauer, Anders Rydholm

{"title":"The Scandinavian Sarcoma Group: 30 years' experience.","authors":"Thor Alvegård, Kirsten Sundby Hall, Henrik Bauer, Anders Rydholm","doi":"10.1080/17453690610046602","DOIUrl":"https://doi.org/10.1080/17453690610046602","url":null,"abstract":"Background and purpose The Scandinavian Sarcoma Group (SSG) XIV protocol was based upon the organisations experience from 3 previous osteosarcoma trials and was considered best standard of care for patients with extremity localised, non-metastatic osteosarcoma. We report the outcome of this protocol. Patients and methods From March 2001 to April 2005, 63 patients recruited from 10 centres in Finland, Sweden and Norway were included in this analysis. Patients received pre-operative chemotherapy consisting of 2 cycles of paired methotrexate (12 g/m(2)), cisplatin (90 mg/m(2)) and doxorubicin (75 mg/m(2)). Good histological responders continued with 3 cycles postoperatively whilst poor responders were salvaged with the addition of 3 cycles of ifusfamide (10-12 g/m(2)). Outcome data was compared to previous SSG osteosarcoma trials. Results With a median follow-up of 64 months for survivors, the projected metastasis-free and sarcoma-related survivals at 5 years were 69% and 77%, respectively. 84% of the patients were treated with limb salvage surgery (49 patients) or rotationplasty (4 patients). 3 toxic deaths (5%) were recorded, all related to acute chemotherapy toxicity. The 5-year metastasis-free survival of patients receiving salvage therapy was 47% compared to 89% for good histological responders that only received the 3 drug combination postoperatively. Interpretation Outcome in the SSG XIV protocol compares favourably to previous SSG osteosarcoma trials and other published trials. The addition of ifosfamide to poor responders as an add on treatment did not improve outcome for poor responders to a similar level as for good responders. In a multi-institutional setting limb salvage surgery can safely be used in more than 80% of the patients. (Less)","PeriodicalId":87168,"journal":{"name":"Acta orthopaedica. Supplementum","volume":"80 334","pages":"1-104"},"PeriodicalIF":0.0,"publicationDate":"2009-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17453690610046602","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28513529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 34

Surgical advances in periacetabular osteotomy for treatment of hip dysplasia in adults. 髋臼周围截骨术治疗成人髋关节发育不良的手术进展。

Acta orthopaedica. Supplementum Pub Date : 2009-04-01 DOI: 10.1080/17453690610046585

Anders Troelsen

{"title":"Surgical advances in periacetabular osteotomy for treatment of hip dysplasia in adults.","authors":"Anders Troelsen","doi":"10.1080/17453690610046585","DOIUrl":"https://doi.org/10.1080/17453690610046585","url":null,"abstract":"Introduction: Hip dysplasia is characterized by an excessively oblique and shallow acetabulum with insufficient coverage of the femoral head. It is a known cause of pain and the development of early osteoarthritis in young adults. The periacetabular osteotomy is the joint-preserving treatment of choice in young adults with symptomatic hip dysplasia. The surgical aim of this extensive procedure is to reorient the acetabulum to improve coverage and eliminate the pathological hip joint mechanics. Intraoperative assessment of the achieved acetabular reorientation is therefore crucial. The \"classic\" surgical approaches for the periacetabular osteotomy inflict extensive trauma to the tissues and some involve detachment of muscles. The type of surgical approach may affect the occurrence of complications, duration of surgery, intraoperative blood loss, transfusion requirements, and length of hospital stay. The aims of the PhD thesis were I) to assess the outcome of a new, minimally invasive transsartorial approach for periacetabular osteotomy; II) to compare the minimally invasive approach with the previously used \"classic\" ilioinguinal approach; and III) to assess the reliability of a novel device for intraoperative assessment of the achieved acetabular reorientation.Methods: Three studies underly this PhD thesis. In studies I and II, the experience with the minimally invasive and ilioinguinal approaches was retrospectively assessed by database inquiry and evaluation of radiographic material. Data regarding patient demographics, patient history, intraoperative measures and complications was recorded in a validated database. Center-edge and acetabular index angles were measured in preoperative and postoperative pelvic radiographs to assess preoperative dysplasia and the achieved acetabular reorientation. The well-defined study groups consisted of 94 and 263 periacetabular osteotomies in studies I and II, respectively. In study III, intraoperative angle measurements were carried out prospectively in 35 periacetabular osteotomies. The obtained measures (center-edge and acetabular index angles) were compared with those of postoperative pelvic radiographs. Furthermore, a cadaver study was conducted to evaluate intra- and interobserver variability of the device and to assess whether pelvic positioning influenced the variability of measurements. The applied methodology was critically reviewed.Results: Study I--The minimally invasive approach had the following outcome. The mean duration of surgery was 73 min and the median intraoperative blood loss was 250 ml. Blood transfusion was required following 3% of the procedures. There were no cases of moderate or severe technical and neurovascular complications, and the achieved center-edge and acetabular index angles suggest that optimal reorientation can be achieved. Hip joint survival with total hip arthroplasty as the end point was 98% at 4.3 year","PeriodicalId":87168,"journal":{"name":"Acta orthopaedica. Supplementum","volume":"80 332","pages":"1-33"},"PeriodicalIF":0.0,"publicationDate":"2009-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17453690610046585","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28404285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

Perthes' disease in Norway. A prospective study on 425 patients. 挪威的珀尔塞斯病。一项对425名患者的前瞻性研究。

Acta orthopaedica. Supplementum Pub Date : 2009-04-01 DOI: 10.1080/17453690610046594

Ola Wiig

引用次数: 8