Biosecurity and bioterrorism : biodefense strategy, practice, and science最新文献_第3页

Global health security agenda and the international health regulations: moving forward. 全球卫生安全议程和国际卫生条例:向前迈进。

Biosecurity and bioterrorism : biodefense strategy, practice, and science Pub Date : 2014-09-01 DOI: 10.1089/bsp.2014.0038

Rebecca Katz, Erin M Sorrell, Sarah A Kornblet, Julie E Fischer

{"title":"Global health security agenda and the international health regulations: moving forward.","authors":"Rebecca Katz, Erin M Sorrell, Sarah A Kornblet, Julie E Fischer","doi":"10.1089/bsp.2014.0038","DOIUrl":"https://doi.org/10.1089/bsp.2014.0038","url":null,"abstract":"The launch of the Global Health Security Agenda (GHSA) in February 2014 capped over a decade of global efforts to develop new approaches to emerging and reemerging infectious diseases-part of the growing recognition that disease events, whether natural, accidental, or intentional, threaten not just public health, but national, regional, and global security interests. In 2005, the United States, along with other Member States of the World Health Organization (WHO), adopted the revised International Health Regulations [IHR (2005)]. The IHR (2005) conferred new responsibilities on WHO and the global health community to coordinate resources for capacity building and emergency response, and on the now-196 States Parties to develop the core capacities required to detect, assess, report, and respond to potential public health emergencies of international concern. Both GHSA and the IHR aim to elevate political attention and encourage participation, coordination, and collaboration by multiple stakeholders, while leveraging previously existing commitments and multilateral efforts. GHSA and the IHR (2005) are platforms for action; how efforts under each will complement each other remains unclear. Mechanisms that measure progress under these 2 overlapping frameworks will aid in focusing resources and in sustaining political momentum for IHR implementation after 2016. ","PeriodicalId":87059,"journal":{"name":"Biosecurity and bioterrorism : biodefense strategy, practice, and science","volume":"12 5","pages":"231-8"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/bsp.2014.0038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32695533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 33

Bridging the health security divide: department of defense support for the global health security agenda. 弥合卫生安全鸿沟:国防部对全球卫生安全议程的支持。

Biosecurity and bioterrorism : biodefense strategy, practice, and science Pub Date : 2014-09-01 DOI: 10.1089/bsp.2014.0055

Robin M Moudy, Michael Ingerson-Mahar, Jordan Kanter, Ashley M Grant, Dara R Fisher, Franca R Jones

{"title":"Bridging the health security divide: department of defense support for the global health security agenda.","authors":"Robin M Moudy, Michael Ingerson-Mahar, Jordan Kanter, Ashley M Grant, Dara R Fisher, Franca R Jones","doi":"10.1089/bsp.2014.0055","DOIUrl":"https://doi.org/10.1089/bsp.2014.0055","url":null,"abstract":"In 2011, President Obama addressed the United Nations General Assembly and urged the global community to come together to prevent, detect, and fight every kind of biological danger, whether a pandemic, terrorist threat, or treatable disease. Over the past decade, the United States and key international partners have addressed these dangers through a variety of programs and strategies aimed at developing and enhancing countries' capacity to rapidly detect, assess, report, and respond to acute biological threats. Despite our collective efforts, however, an increasingly interconnected world presents heightened opportunities for human, animal, and zoonotic diseases to emerge and spread globally. Further, the technical capabilities required to develop biological agents into a weapon are relatively low. The launch of the Global Health Security Agenda (GHSA) provides an opportunity for the international community to enhance the linkages between the health and security sectors, accelerating global efforts to prevent avoidable epidemics and bioterrorism, detect threats early, and respond rapidly and effectively to biological threats. The US Department of Defense (DoD) plays a key role in achieving GHSA objectives through its force health protection, threat reduction, and biodefense efforts at home and abroad. This article focuses on GHSA activities conducted in the DoD Office of the Assistant Secretary of Defense for Nuclear, Chemical, and Biological Defense. ","PeriodicalId":87059,"journal":{"name":"Biosecurity and bioterrorism : biodefense strategy, practice, and science","volume":"12 5","pages":"247-53"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/bsp.2014.0055","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32695534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Leveraging the laboratory response network model for the global health security agenda. 利用实验室反应网络模式促进全球卫生安全议程。

Biosecurity and bioterrorism : biodefense strategy, practice, and science Pub Date : 2014-09-01 DOI: 10.1089/bsp.2014.0039

Chris N Mangal, Lucy Maryogo-Robinson

{"title":"Leveraging the laboratory response network model for the global health security agenda.","authors":"Chris N Mangal, Lucy Maryogo-Robinson","doi":"10.1089/bsp.2014.0039","DOIUrl":"https://doi.org/10.1089/bsp.2014.0039","url":null,"abstract":"Promoting global health security as an international priority is a challenge; the US Centers for Disease Control and Prevention (CDC) in its Global Health Security Agenda has articulated the importance of accelerating progress toward a world safe and secure from infectious disease threats. The goals are to (1) prevent and reduce the likelihood of outbreaks-natural, accidental, or intentional; (2) detect threats early to save lives; and (3) respond rapidly and effectively using multisectoral, international coordination and communication. Foundational to this agenda is the World Health Organization (WHO) Revised International Health Regulations (IHR) of 2005, which provide the legal framework for countries to strengthen their health systems in order to be able to respond to any public health emergency of international concern. This article proposes leveraging the distributed structure of the US-managed Laboratory Response Network for Biological Threats Preparedness (LRN-B) to develop the core capacity of laboratory testing and to fulfill the laboratory-strengthening component of the Global Health Security Agenda. The LRN model offers an effective mechanism to detect and respond to public health emergencies of international concern. ","PeriodicalId":87059,"journal":{"name":"Biosecurity and bioterrorism : biodefense strategy, practice, and science","volume":"12 5","pages":"274-83"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/bsp.2014.0039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32695962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

One health security: an important component of the global health security agenda. 一种卫生安全:全球卫生安全议程的重要组成部分。

Biosecurity and bioterrorism : biodefense strategy, practice, and science Pub Date : 2014-09-01 DOI: 10.1089/bsp.2014.0044

Gigi Gronvall, Crystal Boddie, Rickard Knutsson, Michelle Colby

{"title":"One health security: an important component of the global health security agenda.","authors":"Gigi Gronvall, Crystal Boddie, Rickard Knutsson, Michelle Colby","doi":"10.1089/bsp.2014.0044","DOIUrl":"https://doi.org/10.1089/bsp.2014.0044","url":null,"abstract":"The objectives of the Global Health Security Agenda (GHSA) will require not only a \"One Health\" approach to counter natural disease threats against humans, animals, and the environment, but also a security focus to counter deliberate threats to human, animal, and agricultural health and to nations' economies. We have termed this merged approach \"One Health Security.\" It will require the integration of professionals with expertise in security, law enforcement, and intelligence to join the veterinary, agricultural, environmental, and human health experts essential to One Health and the GHSA. Working across such different professions, which occasionally have conflicting aims and different professional cultures, poses multiple challenges, but a multidisciplinary and multisectoral approach is necessary to prevent disease threats; detect them as early as possible (when responses are likely to be most effective); and, in the case of deliberate threats, find who may be responsible. This article describes 2 project areas that exemplify One Health Security that were presented at a workshop in January 2014: the US government and private industry efforts to reduce vulnerabilities to foreign animal diseases, especially foot-and-mouth disease; and AniBioThreat, an EU project to counter deliberate threats to agriculture by raising awareness and implementing prevention and response policies and practices. ","PeriodicalId":87059,"journal":{"name":"Biosecurity and bioterrorism : biodefense strategy, practice, and science","volume":"12 5","pages":"221-4"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/bsp.2014.0044","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32695530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Legal and regulatory capacity to support the global health security agenda. 支持全球卫生安全议程的法律和监管能力。

Biosecurity and bioterrorism : biodefense strategy, practice, and science Pub Date : 2014-09-01 DOI: 10.1089/bsp.2014.0023

Ryan Morhard, Rebecca Katz

引用次数: 1

Health inequalities and infectious disease epidemics: a challenge for global health security. 卫生不平等和传染病流行:对全球卫生安全的挑战。

Biosecurity and bioterrorism : biodefense strategy, practice, and science Pub Date : 2014-09-01 DOI: 10.1089/bsp.2014.0032

Sandra Crouse Quinn, Supriya Kumar

{"title":"Health inequalities and infectious disease epidemics: a challenge for global health security.","authors":"Sandra Crouse Quinn, Supriya Kumar","doi":"10.1089/bsp.2014.0032","DOIUrl":"https://doi.org/10.1089/bsp.2014.0032","url":null,"abstract":"In today's global society, infectious disease outbreaks can spread quickly across the world, fueled by the rapidity with which we travel across borders and continents. Historical accounts of influenza pandemics and contemporary reports on infectious diseases clearly demonstrate that poverty, inequality, and social determinants of health create conditions for the transmission of infectious diseases, and existing health disparities or inequalities can further contribute to unequal burdens of morbidity and mortality. Yet, to date, studies of influenza pandemic plans across multiple countries find little to no recognition of health inequalities or attempts to engage disadvantaged populations to explicitly address the differential impact of a pandemic on them. To meet the goals and objectives of the Global Health Security Agenda, we argue that international partners, from WHO to individual countries, must grapple with the social determinants of health and existing health inequalities and extend their vision to include these factors so that disease that may start among socially disadvantaged subpopulations does not go unnoticed and spread across borders. These efforts will require rethinking surveillance systems to include sociodemographic data; training local teams of researchers and community health workers who are able to not only analyze data to recognize risk factors for disease, but also use simulation methods to assess the impact of alternative policies on reducing disease; integrating social science disciplines to understand local context; and proactively anticipating shortfalls in availability of adequate healthcare resources, including vaccines. Without explicit attention to existing health inequalities and underlying social determinants of health, the Global Health Security Agenda is unlikely to succeed in its goals and objectives. ","PeriodicalId":87059,"journal":{"name":"Biosecurity and bioterrorism : biodefense strategy, practice, and science","volume":"12 5","pages":"263-73"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/bsp.2014.0032","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32695960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 262

Strengthening global health security by developing capacities to deploy medical countermeasures internationally. 通过发展在国际上部署医疗对策的能力，加强全球卫生安全。

Biosecurity and bioterrorism : biodefense strategy, practice, and science Pub Date : 2014-09-01 DOI: 10.1089/bsp.2014.0049

Maria Julia Marinissen, Lauren Barna, Margaret Meyers, Susan E Sherman

{"title":"Strengthening global health security by developing capacities to deploy medical countermeasures internationally.","authors":"Maria Julia Marinissen, Lauren Barna, Margaret Meyers, Susan E Sherman","doi":"10.1089/bsp.2014.0049","DOIUrl":"https://doi.org/10.1089/bsp.2014.0049","url":null,"abstract":"In 2014, the United States in partnership with international organizations and nearly 30 partner countries launched the Global Health Security Agenda (GHSA) to accelerate progress to improve prevention, detection, and response capabilities for infectious disease outbreaks that can cause public health emergencies. Objective 9 of the GHSA calls for improved global access to medical countermeasures and establishes as a target the development of national policy frameworks for sending and receiving medical countermeasures from and to international partners during public health emergencies. The term medical countermeasures refers to vaccines, antimicrobials, therapeutics, and diagnostics that address the public health and medical consequences of chemical, biological, radiological, and nuclear events; pandemic influenza; and emerging infectious diseases. They are stockpiled by a few countries to protect their own populations and by international organizations, such as the World Health Organization (WHO), for the international community, typically for recipients with limited resources. However, as observed during the 2009 H1N1 influenza pandemic, legal, regulatory, logistical, and funding barriers slowed the ability of WHO and countries to quickly deploy or receive vaccine. Had the 2009 H1N1 influenza pandemic been more severe, the world would have been ill prepared to cope with the global demand for rapid access to medical countermeasures. This article summarizes the US government efforts to develop a national framework to deploy medical countermeasures internationally and a number of engagements to develop regional and international mechanisms, thus increasing global capacity to respond to public health emergencies. ","PeriodicalId":87059,"journal":{"name":"Biosecurity and bioterrorism : biodefense strategy, practice, and science","volume":"12 5","pages":"284-91"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/bsp.2014.0049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32695966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Regulatory underpinnings of Global Health security: FDA's roles in preventing, detecting, and responding to global health threats. 全球健康安全的监管基础:FDA在预防、检测和应对全球健康威胁方面的作用。

Biosecurity and bioterrorism : biodefense strategy, practice, and science Pub Date : 2014-09-01 DOI: 10.1089/bsp.2014.0046

Brooke Courtney, Katherine C Bond, Carmen Maher

{"title":"Regulatory underpinnings of Global Health security: FDA's roles in preventing, detecting, and responding to global health threats.","authors":"Brooke Courtney, Katherine C Bond, Carmen Maher","doi":"10.1089/bsp.2014.0046","DOIUrl":"https://doi.org/10.1089/bsp.2014.0046","url":null,"abstract":"In February 2014, health officials from around the world announced the Global Health Security Agenda, a critical effort to strengthen national and global systems to prevent, detect, and respond to infectious disease threats and to foster stronger collaboration across borders. With its increasing global roles and broad range of regulatory responsibilities in ensuring the availability, safety, and security of medical and food products, the US Food and Drug Administration (FDA) is engaged in a range of efforts in support of global health security. This article provides an overview of FDA's global health security roles, focusing on its responsibilities related to the development and use of medical countermeasures (MCMs) for preventing, detecting, and responding to global infectious disease and other public health emergency threats. The article also discusses several areas-antimicrobial resistance, food safety, and supply chain integrity-in which FDA's global health security roles continue to evolve and extend beyond MCMs and, in some cases, beyond traditional infectious disease threats. ","PeriodicalId":87059,"journal":{"name":"Biosecurity and bioterrorism : biodefense strategy, practice, and science","volume":"12 5","pages":"239-46"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/bsp.2014.0046","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32695532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Guatemala's ministry of health rapid response team manuals. 危地马拉卫生部快速反应小组手册。

Biosecurity and bioterrorism : biodefense strategy, practice, and science Pub Date : 2014-09-01 DOI: 10.1089/bsp.2014.0043

Luis Hernandez, Kimberly M Hanson, Lise D Martel

引用次数: 0

Public health emergency planning for children in chemical, biological, radiological, and nuclear (CBRN) disasters. 儿童在化学、生物、放射和核(CBRN)灾害中的公共卫生应急规划。

Biosecurity and bioterrorism : biodefense strategy, practice, and science Pub Date : 2014-07-01 Epub Date: 2014-07-11 DOI: 10.1089/bsp.2014.0036

Michael T Bartenfeld, Georgina Peacock, Stephanie E Griese

引用次数: 22