Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists最新文献

{"title":"Pneumorrhachis as a result of epidural anesthesia","authors":"Shivinder Singh, Haneesh Thakur","doi":"10.1016/j.aat.2015.07.001","DOIUrl":"10.1016/j.aat.2015.07.001","url":null,"abstract":"","PeriodicalId":87042,"journal":{"name":"Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists","volume":"54 1","pages":"Page 37"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.aat.2015.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34100972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cepharanthine alleviates liver injury in a rodent model of limb ischemia–reperfusion","authors":"Yin-Kuang Chang ,&nbsp;Su-Cheng Huang ,&nbsp;Ming-Chang Kao ,&nbsp;Chun-Jen Huang","doi":"10.1016/j.aat.2015.11.004","DOIUrl":"10.1016/j.aat.2015.11.004","url":null,"abstract":"<div><h3>Objectives</h3><p>Limb ischemia–reperfusion (I/R) causes remote organ injury (e.g., liver injury). Oxidation and inflammation are crucial mechanisms. We investigated the effects of cepharanthine, a potent antioxidative and anti-inflammatory drug, on alleviating liver injury induced by limb I/R.</p></div><div><h3>Methods</h3><p>Twenty-four adult male Sprague-Dawley rats were randomized to receive sham operation (Sham), Sham plus cepharanthine, I/R, or I/R plus cepharanthine and designated as the Sham, Sham+Cep, I/R, or I/R+Cep group, respectively (<em>n</em> = 6 in each group). I/R was induced by applying rubber band tourniquets high around each hind limb for 3 hours followed by reperfusion for 24 hours.</p></div><div><h3>Results</h3><p>The plasma levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) of the Sham and Sham+Cep groups were low, and the levels of AST and ALT of the I/R group were significantly higher than those of the Sham group (both <em>p</em> <!-->&lt;<!--> <!-->0.001). By contrast, the AST and ALT of the I/R+Cep group were significantly lower than those of the I/R group (both <em>p</em> <!-->&lt;<!--> <!-->0.001). The hepatic levels of nitric oxide (NO), malondialdehyde (MDA), macrophage inflammatory protein 2 (MIP-2), interleukin-6 (IL-6), and cyclooxygenase-2 (COX-2)/prostaglandin E₂ (PGE₂) of the Sham and Sham+Cep groups were also low. As expected, the NO, MDA, MIP-2, IL-6, and COX-2/PGE₂ of the I/R group were significantly higher than those of the Sham group (all <em>p</em> <!-->&lt;<!--> <!-->0.001). By contrast, the NO, MDA, MIP-2, IL-6, and COX-2/PGE₂ of the I/R+Cep group were significantly lower than those of the I/R group (all <em>p</em> <!-->&lt;<!--> <!-->0.05).</p></div><div><h3>Conclusion</h3><p>Cepharanthine alleviates liver injury in a rodent model of limb I/R. The mechanisms may involve reducing oxidation and inflammation.</p></div>","PeriodicalId":87042,"journal":{"name":"Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists","volume":"54 1","pages":"Pages 11-15"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.aat.2015.11.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82674086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacogenomics for personalized pain medicine","authors":"Tai-Ming Ko ,&nbsp;Chih-Shung Wong ,&nbsp;Jer-Yuarn Wu ,&nbsp;Yuan-Tsong Chen","doi":"10.1016/j.aat.2016.02.001","DOIUrl":"10.1016/j.aat.2016.02.001","url":null,"abstract":"<div><p>Pharmacogenomics aims to unravel the way that human genetic variation affects drug efficacy and toxicity. Genome-wide association studies and candidate gene findings suggest that genetic approaches may help choose the most appropriate drug and dosage while preventing adverse drug reactions (ADRs). Pain is an unpleasant feeling that usually results from tissue damage. The management of different types of pain (acute, chronic, inflammatory, neuropathic, or cancer) is challenging. Currently, drug intervention is the first-line therapy for resolving pain. However, differences in drug efficacy between individuals are common with pain medications. Moreover, some patients experience ADRs after being treated with specific pain drugs. This review discusses the use of drugs for pain management in the context of the recent pharmacogenomic studies on ADRs and drug efficacy.</p></div>","PeriodicalId":87042,"journal":{"name":"Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists","volume":"54 1","pages":"Pages 24-30"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.aat.2016.02.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76810373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subcutaneous emphysema and pneumothorax secondary to subclavian vein catheterization via supraclavicular approach","authors":"Chih-Dou Chou,&nbsp;Yu-Chi Tsung,&nbsp;Fwu-Lin Yang","doi":"10.1016/j.aat.2015.12.003","DOIUrl":"10.1016/j.aat.2015.12.003","url":null,"abstract":"","PeriodicalId":87042,"journal":{"name":"Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists","volume":"54 1","pages":"Pages 35-36"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.aat.2015.12.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80110539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Undertreatment of cancer pain” [Acta Anaesthesiol Taiwanica 53 (2015) 58–61]","authors":"S. Lee, Cheng-Hsu Wang","doi":"10.1016/J.AAT.2015.09.001","DOIUrl":"https://doi.org/10.1016/J.AAT.2015.09.001","url":null,"abstract":"","PeriodicalId":87042,"journal":{"name":"Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists","volume":"8 1","pages":"154"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72992229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anesthetic management of a pregnant patient with cerebral angioma scheduled for caesarean section.","authors":"P. Bhakta, Ashfaq Hussain, Vikash Singh, A. Bhakta","doi":"10.1016/j.aat.2015.08.002","DOIUrl":"https://doi.org/10.1016/j.aat.2015.08.002","url":null,"abstract":"","PeriodicalId":87042,"journal":{"name":"Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists","volume":"166 1","pages":"148-9"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76454428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Codeine consumption from over-the-counter anti-cough syrup in Taiwan: A useful indicator for opioid abuse","authors":"Ming-Yu Lo ,&nbsp;Ming Wei Ong ,&nbsp;Jaung-Geng Lin ,&nbsp;Wei-Zen Sun","doi":"10.1016/j.aat.2015.10.001","DOIUrl":"https://doi.org/10.1016/j.aat.2015.10.001","url":null,"abstract":"<div><h3>Objective</h3><p>Over-the-counter (OTC) anti-cough preparations, many of which contain codeine (an opioid) or dextromethorphan (an opioid-like), are widely available in Taiwan and thus susceptible to overuse or abuse. We aimed to investigate whether opioids in the form of OTC antitussives play a significant role in medication abuse in Taiwan.</p></div><div><h3>Methods</h3><p>Data on the consumption of codeine and dextromethorphan in antitussives and expectorants from 2011 through 2014 in Taiwan were provided by IMS Health (Intercontinental Marketing Services). These data were then analyzed for trends and variance according to availability, as prescription or OTC, and according to drug type, as codeine or dextromethorphan, in order to form four primary sectors under opioid-containing anti-cough syrup consumption.</p></div><div><h3>Results</h3><p>From 2011 to 2014, use of opioid-containing cough syrup fluctuated between 6% and 9% from year to year for all cough syrup consumption, with an overall declining trend (11.3% per year relative to 2011). Within the underlying sectors, mean consumption for prescription dextromethorphan (61.4%) outstripped the other three sectors, followed in decreasing order by OTC codeine (20.2%), OTC dextromethorphan (10.5%), and prescription codeine (8.0%). However, movement in consumption corresponded mainly with OTC codeine, whose variance greatly exceeded that of the other sectors, which follow in order of decreasing variance as OTC dextromethorphan, prescription dextromethorphan, and prescription codeine.</p></div><div><h3>Conclusion</h3><p>The fairly low and stable consumption of prescription codeine suggested that physicians in Taiwan were careful in prescribing codeine, and that the medical demand for codeine was stable. The large variance in OTC codeine consumption suggested that a minority of consumers purchased significant quantities of codeine for non-medical purposes. Although opioids in cough syrup were not a large part of overall consumption and thus not widely abused, the data revealed that OTC codeine-containing cough syrup may serve as an indicator of potential drug abuse in the population as compared to prescription codeine.</p></div>","PeriodicalId":87042,"journal":{"name":"Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists","volume":"53 4","pages":"Pages 135-138"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.aat.2015.10.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91653793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Undertreatment of cancer pain” [Acta Anaesthesiol Taiwanica 53 (2015) 58–61]","authors":"Shiu-Yu C. Lee ,&nbsp;Cheng-Hsu Wang","doi":"10.1016/j.aat.2015.09.001","DOIUrl":"https://doi.org/10.1016/j.aat.2015.09.001","url":null,"abstract":"","PeriodicalId":87042,"journal":{"name":"Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists","volume":"53 4","pages":"Page 154"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.aat.2015.09.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90007679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-hand maneuver to facilitate flexible fiber-optic bronchoscope-guided nasotracheal intubation in sedated patients","authors":"Chih-Kai Shih,&nbsp;Chia-Ching Wu,&nbsp;Tsai-Tsen Ji","doi":"10.1016/j.aat.2015.08.001","DOIUrl":"10.1016/j.aat.2015.08.001","url":null,"abstract":"","PeriodicalId":87042,"journal":{"name":"Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists","volume":"53 4","pages":"Pages 150-151"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.aat.2015.08.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34163314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The law of Yin and Yang for controlled drugs ecosystem: Maximal analgesia with minimal abuse","authors":"Wei-Zen Sun","doi":"10.1016/j.aat.2015.10.003","DOIUrl":"10.1016/j.aat.2015.10.003","url":null,"abstract":"","PeriodicalId":87042,"journal":{"name":"Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists","volume":"53 4","pages":"Pages 117-118"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.aat.2015.10.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90385550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}