Basic life sciences最新文献_第10页

Assessment of changes in extra-cellular water and total body water using multi-frequency bio-electrical impedance. 利用多频生物电阻抗评估细胞外水和全身水的变化。

Basic life sciences Pub Date : 1993-01-01 DOI: 10.1007/978-1-4899-1268-8_29

P Deurenberg, F J Schouten, A Andreoli, A de Lorenzo

引用次数: 28

Characteristics of an accelerator based system for in vivo aluminium measurement in peripheral bone. 基于加速器的外周骨体内铝测量系统的特性。

Basic life sciences Pub Date : 1993-01-01 DOI: 10.1007/978-1-4899-1268-8_64

S Green, D A Bradley, P J Mountford, W D Morgan, D R Chettle, D R Weaver

引用次数: 4

Performance of the bismuth germanate total body chlorine analyzer. 锗酸铋总氯分析仪的性能。

Basic life sciences Pub Date : 1993-01-01 DOI: 10.1007/978-1-4899-1268-8_82

N Blagojevic, B J Allen, J Russell

引用次数: 0

Prevention of genotoxic effects by dietary constituents in various organs of mice treated with nitrosamines. 饮食成分对亚硝胺处理小鼠各器官遗传毒性的预防作用。

Basic life sciences Pub Date : 1993-01-01 DOI: 10.1007/978-1-4615-2984-2_39

S Knasmüller, W Huber, R Schulte-Hermann

引用次数: 4

Extracellular interception of mutagens. 诱变剂的细胞外拦截。

Basic life sciences Pub Date : 1993-01-01 DOI: 10.1007/978-1-4615-2984-2_5

D M Shankel, S Kuo, C Haines, L A Mitscher

{"title":"Extracellular interception of mutagens.","authors":"D M Shankel, S Kuo, C Haines, L A Mitscher","doi":"10.1007/978-1-4615-2984-2_5","DOIUrl":"https://doi.org/10.1007/978-1-4615-2984-2_5","url":null,"abstract":"<p><p>Extracellular interception of mutagens by excreted enzymes or by chemical agents that react with or bind to formed mutagens provides an important means of defense against chemical mutagens/carcinogens. Kada and Shimoi have classified molecules that function in this manner as \"desmutagens,\" and many of them are natural cellular metabolites. Among the specific mechanisms that such agents may employ are: prevention of the activation of \"promutagens\" to mutagens; stimulation of enzymes (e.g., glutathione-S-transferase) that catalyze the binding/inactivation of damaging electrophiles; direct binding and concomitant inactivation of promutagens or mutagens; interference with uptake of mutagens into cells; etc. De Flora and Ramel have provided an excellent discussion of the mechanisms of these agents and a proposed classification scheme. Drawing on work from our own laboratories and other recent examples in the literature, several examples of mechanistic approaches to these studies using natural plant-derived materials, e.g., humic acid, Glycyrrhiza glabra extract, glutathione, and bioflavonoids, are also described. Antioxidants and agents that conjugate electrophiles will be among the modes of action described for obtaining the goal of intercepting mutagens/carcinogens.</p>","PeriodicalId":8697,"journal":{"name":"Basic life sciences","volume":"61 ","pages":"65-74"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19292158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Mechanisms of inhibition of tumor progression. 抑制肿瘤进展的机制。

Basic life sciences Pub Date : 1993-01-01 DOI: 10.1007/978-1-4615-2984-2_26

B S Warren, T J Slaga

引用次数: 18

Histopathology of human intraepithelial neoplasia with implications for chemoprevention strategy. 人上皮内瘤变的组织病理学与化学预防策略的意义。

Basic life sciences Pub Date : 1993-01-01 DOI: 10.1007/978-1-4615-2984-2_27

C W Boone, G J Kelloff, V E Steele

引用次数: 0

Spontaneous mutations and fidelogens. 自发突变和基因原。

Basic life sciences Pub Date : 1993-01-01 DOI: 10.1007/978-1-4615-2984-2_41

R C von Borstel, U G Hennig