Bangladesh Pharmaceutical Journal最新文献_第7页

A Study on the Prescription Trend of Proton Pump Inhibitors in Major Divisions of Bangladesh 孟加拉国主要地区质子泵抑制剂处方趋势研究

Bangladesh Pharmaceutical Journal Pub Date : 2022-07-30 DOI: 10.3329/bpj.v25i2.60972

M. Rashid, J. Sultana, A. Jahan, M. Saifuddin, Md. Selim Reza

{"title":"A Study on the Prescription Trend of Proton Pump Inhibitors in Major Divisions of Bangladesh","authors":"M. Rashid, J. Sultana, A. Jahan, M. Saifuddin, Md. Selim Reza","doi":"10.3329/bpj.v25i2.60972","DOIUrl":"https://doi.org/10.3329/bpj.v25i2.60972","url":null,"abstract":"The objective of this study is to investigate the prescription pattern of proton pump inhibitors (PPIs) in association with patients’ age, gender and type of hospital visited (government or private), location of the hospital and doctors’ specialty in major divisions of Bangladesh. The secondary objective of this study was to analyze the current market size, share and growth of PPIs in the antiulcer drug market. A crosssectional survey of drug prescriptions was done at hospitals and clinics (private practices) between April 2021 to June 2021 of 7 divisions in Bangladesh. A total of 386 prescriptions, containing 2354 medicines, from 21 districts/areas of 7 divisions in Bangladesh were reviewed to determine the trend of prescribing PPIs. Market data of PPIs were collected from a secondary source (IQVIA). The data collected from the survey were tabulated, analyzed and graphically presented using Microsoft Office Excel 2016. Collected data were entered into the SPSS19.0 statistical software “R” and analyzed. Prescribed antiulcer drugs included Esomeprazole (70.2%), Rabeprazole (7.8%), Omeprazole (4.7%), Dexlansoprazole (4.4%), Pantoprazole (3.1%), and Lansoprazole (0.3%); and 9.3% of collected prescriptions had no anti-ulcerant. There was no association between gender and PPIs prescribed, nor across the type of hospital visited. Only the regression coefficient relating to the patient's age is statistically significant (β=0.01, p<0.05) in overall drug consumption. Along with nonspecific explanations, there were twelve specific reasons for prescribing antiulcer drug generics where the majority of the cases were attributed to NSAID-induced acidity (36%).\u0000Bangladesh Pharmaceutical Journal 25(2): 209-217, 2022 (July)","PeriodicalId":8695,"journal":{"name":"Bangladesh Pharmaceutical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83040933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Updates on COVID-19: Virology, Etiology, Epidemiology, Pathogenesis, Diagnosis, Transmission and Prevention COVID-19最新进展:病毒学、病因学、流行病学、发病机制、诊断、传播和预防

Bangladesh Pharmaceutical Journal Pub Date : 2022-07-30 DOI: 10.3329/bpj.v25i2.60966

Sumayea Kabir Saba, F. Khan, Samantha Lamia, Md. Iqbal Shahid, Tahsin Anika, S. Akhter, Khadizatul Fariha Chowdhury, Umma Mysha Tannum Arpita, Shanta Islam, Khandaker Amirul Momenin, Shah Alam, Kanij Fatima Tisha, Md. Jamal Hossain, Md. Harun Or Rashid, M. Sarker

{"title":"Updates on COVID-19: Virology, Etiology, Epidemiology, Pathogenesis, Diagnosis, Transmission and Prevention","authors":"Sumayea Kabir Saba, F. Khan, Samantha Lamia, Md. Iqbal Shahid, Tahsin Anika, S. Akhter, Khadizatul Fariha Chowdhury, Umma Mysha Tannum Arpita, Shanta Islam, Khandaker Amirul Momenin, Shah Alam, Kanij Fatima Tisha, Md. Jamal Hossain, Md. Harun Or Rashid, M. Sarker","doi":"10.3329/bpj.v25i2.60966","DOIUrl":"https://doi.org/10.3329/bpj.v25i2.60966","url":null,"abstract":"COVID-19 is a pandemic malady caused by SARS-CoV-2, a novel coronavirus. It is a global threat that has affected 223 countries and territories all over the world. According to the WHO report as of April 06, 2022 coronavirus has affected 492,189,439 people globally with 6,159,474 confirmed deaths. The pandemic of COVID-19 has badly affected Bangladesh likewise many other countries of the world. According to Worldometer report on 06 April 2022 the number of confirmed cases of COVID-19 were 1,951,903 with 29,123 deaths, and 1,886,036 COVID-19 recoveries in Bangladesh. After originating from China, this notorious virus has been spread to almost all the countries of the world. Its spike protein aids in binding with the ACE2 receptors of the cell membrane resulting in cell entry, replication, and induction of inflammatory and pro-inflammatory responses leading to the pathogenic condition. The novel COVID-19 virus has structural and genetic similarity with its predecessors specially SARS-CoV and MERS-CoV. This review presents the existing literature on COVID-19 and discusses different aspects of COVID-19 including virology, etiology, epidemiology, pathogenesis, diagnosis, transmission and susceptibility and preventive measures of COVID-19.\u0000Bangladesh Pharmaceutical Journal 25(2): 143-163, 2022 (July)","PeriodicalId":8695,"journal":{"name":"Bangladesh Pharmaceutical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84619970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Aphananthe aspera (Thunb.) Planch.: An Unexploited Eastern Asian Species from the Center of Biodiversity 大黄(拇指)木板。:来自生物多样性中心的一种未开发的东亚物种

Bangladesh Pharmaceutical Journal Pub Date : 2022-07-30 DOI: 10.3329/bpj.v25i2.60973

Maliha Momtaj, Safaet Alam, A. Sultana, M. Rashid

{"title":"Aphananthe aspera (Thunb.) Planch.: An Unexploited Eastern Asian Species from the Center of Biodiversity","authors":"Maliha Momtaj, Safaet Alam, A. Sultana, M. Rashid","doi":"10.3329/bpj.v25i2.60973","DOIUrl":"https://doi.org/10.3329/bpj.v25i2.60973","url":null,"abstract":"Aphananthe Aspera (Thunb.) Planch. is a towering woody deciduous tree and belongs to riparian forest territory. It is highly allocated to the Northern region of Eastern Asia especially Korea, China, Northern Vietnam, and Japan to be the richest countries with this species. The plants were assayed based on various types of methods including extraction. Based on folkloric usage it is important to treat acne, inflammation and cancer. Google Scholar, Web of Science, PubMed, Science Direct, and MEDLINE etc. are the electronic versions from which many bibliographic records were thoroughly explored to identify, collect, and analyze available information relevant to A. aspera. The extracted data were scrutinized in order to have a better understanding of the existing research on this species and to look into the plant's future potential in pharmaceutical research. This study aims to offer current knowledge on botany, distribution, ethnomedicinal applications, pharmacological actions, clinical study and reported phytochemicals of A. aspera. Finally, this plant is still recommended for extensive research to explore prospective novel sources of novel therapeutic agents as there are very little data available on this plant to the best of our knowledge. Extensive research on this plant can open a new horizon to discover novel therapeutics.\u0000Bangladesh Pharmaceutical Journal 25(2): 218-228, 2022 (July)","PeriodicalId":8695,"journal":{"name":"Bangladesh Pharmaceutical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72942841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analgesic, Hypoglycemic and Antidiarrheal Activities Screening of Canna indica L. 美人蕉镇痛、降糖、止泻作用的筛选。

Bangladesh Pharmaceutical Journal Pub Date : 2022-07-30 DOI: 10.3329/bpj.v25i2.60965

N. Sultana, Mahfuza Afroz Soma, Md. Abdur Rashid

引用次数: 2

New Drug Approvals Vol. 25(2) 新药批准第25卷(2)

Bangladesh Pharmaceutical Journal Pub Date : 2022-07-30 DOI: 10.3329/bpj.v25i2.61126

M. Rashid

引用次数: 0

Current Herbal News Vol. 25(2) 现代草药新闻第25卷(2)

Bangladesh Pharmaceutical Journal Pub Date : 2022-07-30 DOI: 10.3329/bpj.v25i2.61129

M. Rashid

引用次数: 0

Nanotechnology in COVID-19 Diagnosis and Treatment: A Bibliometric Analysis 纳米技术在COVID-19诊断和治疗中的应用:文献计量学分析

Bangladesh Pharmaceutical Journal Pub Date : 2022-07-30 DOI: 10.3329/bpj.v25i2.60971

Ripa Kundu, Faria Nasrin, T. Saha, Md. Selim Reza

{"title":"Nanotechnology in COVID-19 Diagnosis and Treatment: A Bibliometric Analysis","authors":"Ripa Kundu, Faria Nasrin, T. Saha, Md. Selim Reza","doi":"10.3329/bpj.v25i2.60971","DOIUrl":"https://doi.org/10.3329/bpj.v25i2.60971","url":null,"abstract":"There is an utmost urgency of having new and advanced diagnostics as well as therapeutic alternatives along with the conventional methods to treat coronavirus disease 2019 (COVID-19). For this purpose, different strategies must be explored for the advancement of testing capacity, developing effective treatments, and developing safe vaccines that provide long-term immunity. Nanotechnology has been found effective against COVID-19 in terms of diagnosis, prevention, and treatment. The diameter of SARS-CoV-2 (60–140 nm) is similar to nanoparticles. This is why, synthetic nanoparticles can precisely resemble SARS-CoV-2, and efficiently interact with the viral proteins and counter this virus. Nanotechnology offers benefits by developing efficient and cost-effective diagnosis methods and facilitating the improvement of drug properties through nano-carriers, namely liposomes, micelles, metallic nanoparticles, etc. The bibliometric analysis evaluates scholarly contributions using mathematical and statistical methodologies. In this study, the bibliometric analysis investigated the publication trends of nanoparticles and their application in COVID-19 diagnosis and treatment. We have systematically searched the different search engines and publishers (Scopus, PubMed, and Google scholar) from 2020 to 2021, and various visual maps were generated to show, the most- relevant authors, sources, countries, topics, and keywords by using a software called VOSviewer. The findings indicate the advancement of nanotechnology in the diagnosis and therapy of COVID-19. At last, the bibliometric analysis of nanoparticles for COVID-19 diagnosis and treatment provides a clear view of the future research directions and identifies the potential challenges and opportunities. This may pave the way for new researchers to find the proper subfields in nanoparticle-related research areas for combating the COVID-19.\u0000Bangladesh Pharmaceutical Journal 25(2): 199-208, 2022 (July)","PeriodicalId":8695,"journal":{"name":"Bangladesh Pharmaceutical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79015007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Possible Role of Phenolics and Flavonoids in Antioxidant, Cytotoxic and Thrombolytic Activities of Eclipta prostata L. 酚类物质和黄酮类物质在黄芪抗氧化、细胞毒和溶栓活性中的可能作用。

Bangladesh Pharmaceutical Journal Pub Date : 2022-07-30 DOI: 10.3329/bpj.v25i2.60967

M. Rashid, Juthika Das, Anika Akter, J. Uddin, Nazni Parvin, F. R. Laboni, M. Sarker, Nurul Karim

{"title":"Possible Role of Phenolics and Flavonoids in Antioxidant, Cytotoxic and Thrombolytic Activities of Eclipta prostata L.","authors":"M. Rashid, Juthika Das, Anika Akter, J. Uddin, Nazni Parvin, F. R. Laboni, M. Sarker, Nurul Karim","doi":"10.3329/bpj.v25i2.60967","DOIUrl":"https://doi.org/10.3329/bpj.v25i2.60967","url":null,"abstract":"Eclipta prostata (E. prostata) L, is a herbal medicinal plant, which is reported to contain phenolics and flavonoids, but very little is known about its bioactive potentials. In this report, we reexamined the phenols and flavonoid content and evaluated different bioactivities of organic soluble fractions from the shoots of E. prostata for the first time. Among the extractives, chloroform soluble fraction (CSF) possessed the highest content of phenols (156.03 ± 0.52 mg gallic acid equivalent /g of dry extract) and flavonoids (67.47 ± 0.56 mg quercetin equivalent /g of dry extract) and exhibited the most potent antioxidant properties in terms of total antioxidant capacity (198.71 ± 0.89 mg ascorbic acid equivalent/g of dry extract) and DPPH free radical scavenging ability (IC50; 17.68 ± 0.32 μg/ml). Similarly, CSF showed the highest cytotoxicity with LC50 values of 16.03±0.23 μg/ml, and thrombolytic activity with 36.06 ± 0.39% clot lysis. A significant correlation was observed between flavonoid content and total antioxidant capacity (r2 = 0.894, p < 0.05), while high correlation was seen between polyphenols and flavonoid content with free radical scavenging, total antioxidant capacity and cytotoxicity (r2 = 0.612 - 0.928). These findings suggest that E. prostata is a precious source of polyphenols having potential bioactivities, which could be utilized for the management of lifestyle diseases.\u0000Bangladesh Pharmaceutical Journal 25(2): 164-174, 2022 (July)","PeriodicalId":8695,"journal":{"name":"Bangladesh Pharmaceutical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89814459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Quantitative and Qualitative Estimation of Marketed Naproxen Tablets Available in Bangladesh 孟加拉国市售萘普生片的定量和定性评价

Bangladesh Pharmaceutical Journal Pub Date : 2022-07-30 DOI: 10.3329/bpj.v25i2.60968

Tanoy Saha, Md. Hassan Kawsar, Md. kamrul Islam, Safaet Alam, Mirazul Islam, Nafla Hakim, Md. Jamal Hossain

{"title":"Quantitative and Qualitative Estimation of Marketed Naproxen Tablets Available in Bangladesh","authors":"Tanoy Saha, Md. Hassan Kawsar, Md. kamrul Islam, Safaet Alam, Mirazul Islam, Nafla Hakim, Md. Jamal Hossain","doi":"10.3329/bpj.v25i2.60968","DOIUrl":"https://doi.org/10.3329/bpj.v25i2.60968","url":null,"abstract":"Naproxen is a non-steroidal anti-inflammatory drug (NSAID) working as a non-selective cyclooxygenase (COX) inhibitor to treat inflammation, pain, fever, and various disease conditions. The current study was conducted to determine and compare several in vitro quality parameters, often commercially available 500 mg naproxen brands available in Bangladesh. According to the existing protocols, different physical parameters such as uniformity of weight, hardness, friability, disintegration time and dissolution were determined. A validated UV-visible spectrophotometric approach was used to assess the content uniformity of drug material in the collected brands. All the brands taken for this study complied with the official specifications of physical parameters. These brands contained active ingredients ranging from 91.37% up to 101.18%. On the other hand, two brands (C4 and C8) of naproxen tablets failed to meet the specification of United States Pharmacopoeia (USP), 90-110% of the labeled claim for the 500 mg naproxen tablet. These sub-standard brands possessed only 88.16% and 86.67% naproxen sodium. In conclusion, the current study indicated that eight out of the ten brands complied with quality parameters and can be used correspondingly.\u0000Bangladesh Pharmaceutical Journal 25(2): 175-179, 2022 (July)","PeriodicalId":8695,"journal":{"name":"Bangladesh Pharmaceutical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90907394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Indications & Dosage Forms for Existing Drugs Vol. 25(2) 现有药物的新适应症和剂型第25卷(2)

Bangladesh Pharmaceutical Journal Pub Date : 2022-07-30 DOI: 10.3329/bpj.v25i2.61128

Md. Abdur Rashid

引用次数: 0