Nanotechnology in COVID-19 Diagnosis and Treatment: A Bibliometric Analysis

Ripa Kundu, Faria Nasrin, T. Saha, Md. Selim Reza
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Abstract

There is an utmost urgency of having new and advanced diagnostics as well as therapeutic alternatives along with the conventional methods to treat coronavirus disease 2019 (COVID-19). For this purpose, different strategies must be explored for the advancement of testing capacity, developing effective treatments, and developing safe vaccines that provide long-term immunity. Nanotechnology has been found effective against COVID-19 in terms of diagnosis, prevention, and treatment. The diameter of SARS-CoV-2 (60–140 nm) is similar to nanoparticles. This is why, synthetic nanoparticles can precisely resemble SARS-CoV-2, and efficiently interact with the viral proteins and counter this virus. Nanotechnology offers benefits by developing efficient and cost-effective diagnosis methods and facilitating the improvement of drug properties through nano-carriers, namely liposomes, micelles, metallic nanoparticles, etc. The bibliometric analysis evaluates scholarly contributions using mathematical and statistical methodologies. In this study, the bibliometric analysis investigated the publication trends of nanoparticles and their application in COVID-19 diagnosis and treatment. We have systematically searched the different search engines and publishers (Scopus, PubMed, and Google scholar) from 2020 to 2021, and various visual maps were generated to show, the most- relevant authors, sources, countries, topics, and keywords by using a software called VOSviewer. The findings indicate the advancement of nanotechnology in the diagnosis and therapy of COVID-19. At last, the bibliometric analysis of nanoparticles for COVID-19 diagnosis and treatment provides a clear view of the future research directions and identifies the potential challenges and opportunities. This may pave the way for new researchers to find the proper subfields in nanoparticle-related research areas for combating the COVID-19. Bangladesh Pharmaceutical Journal 25(2): 199-208, 2022 (July)
纳米技术在COVID-19诊断和治疗中的应用:文献计量学分析
除了传统方法之外,迫切需要新的先进诊断方法和治疗方案来治疗2019冠状病毒病(COVID-19)。为此目的,必须探索不同的战略,以提高检测能力、开发有效的治疗方法和开发提供长期免疫的安全疫苗。纳米技术已被发现在诊断、预防和治疗方面对COVID-19有效。SARS-CoV-2的直径(60-140纳米)与纳米颗粒相似。这就是为什么合成纳米颗粒可以精确地类似于SARS-CoV-2,并有效地与病毒蛋白相互作用并对抗这种病毒。纳米技术通过脂质体、胶束、金属纳米粒子等纳米载体,开发了高效、经济的诊断方法,促进了药物性能的改善。文献计量学分析使用数学和统计方法评估学术贡献。本研究通过文献计量学分析研究纳米颗粒的发表趋势及其在COVID-19诊断和治疗中的应用。我们系统地搜索了不同的搜索引擎和出版商(Scopus, PubMed和Google scholar),从2020年到2021年,并使用名为VOSviewer的软件生成了各种可视化地图,以显示最相关的作者,来源,国家,主题和关键词。这一发现表明纳米技术在COVID-19诊断和治疗方面取得了进展。最后,通过文献计量学分析纳米颗粒在COVID-19诊断和治疗中的应用,明确了未来的研究方向,并指出了潜在的挑战和机遇。这可能为新的研究人员在纳米颗粒相关研究领域找到合适的子领域以对抗COVID-19铺平道路。孟加拉国药学杂志25(2):199- 208,2022(7月)
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