Autonomic Neuroscience最新文献

The use and effectiveness of exercise for managing postural orthostatic tachycardia syndrome in young adults with joint hypermobility and related conditions: A scoping review 在患有关节过度活动症及相关疾病的年轻成年人中，使用运动来控制体位性正位性心动过速综合征的方法及其有效性：范围界定综述

Autonomic Neuroscience Pub Date : 2024-02-01 DOI: 10.1016/j.autneu.2024.103156

Karen C. Peebles, Charl Jacobs, Logan Makaroff, Verity Pacey

引用次数: 0

Autonomic function testing in long-COVID syndrome patients with orthostatic intolerance 长冠综合征直立不耐受患者的自主神经功能检测

Autonomic Neuroscience Pub Date : 2022-06-01 DOI: 10.1016/j.autneu.2022.102997

Ahmed M. Eldokla, Sara T. Ali

引用次数: 9

Asymmetry of the pupillary light reflex during a cold pressor test 冷压试验中瞳孔光反射的不对称性

Autonomic Neuroscience Pub Date : 2022-05-01 DOI: 10.1016/j.autneu.2022.102989

P. Drummond

引用次数: 0

Sympathovagal imbalance in early ischemic stroke is linked to impaired cerebral autoregulation and increased infarct volumes 早期缺血性卒中的交感迷走神经失衡与大脑自我调节受损和梗死体积增加有关

Autonomic Neuroscience Pub Date : 2022-05-01 DOI: 10.1016/j.autneu.2022.102986

P. Castro, J. Serrador, Farzaneh A. Sorond, E. Azevedo, Isabel Rocha

引用次数: 4

Sympathetic nervous system hyperactivity results in potent cerebral hypoperfusion in swine 交感神经系统过度活跃导致猪脑灌注不足

Autonomic Neuroscience Pub Date : 2022-05-01 DOI: 10.1016/j.autneu.2022.102987

Wi Jin Kim, M. Dacey, Milan Samarage, D. Zarrin, K. Goel, Christopher A Chan, Xin Qi, Anthony C. Wang, K. Shivkumar, J. Ardell, G. Colby

引用次数: 3

Early ovarian hormone deprivation increases cardiac contractility in old female rats—Role of physical training 早期卵巢激素剥夺增加老年雌性大鼠心脏收缩力——体育锻炼的作用

Autonomic Neuroscience Pub Date : 2019-05-01 DOI: 10.1249/01.mss.0000561508.53212.ea

A. C. Felix, A. Gastaldi, S. G. Dutra, Ana Caroline Silva de Freitas, S. V. Philbois, Tábata de Paula Facioli, V. J. D. da Silva, T. H. Fares, H. C. D. de Souza

{"title":"Early ovarian hormone deprivation increases cardiac contractility in old female rats—Role of physical training","authors":"A. C. Felix, A. Gastaldi, S. G. Dutra, Ana Caroline Silva de Freitas, S. V. Philbois, Tábata de Paula Facioli, V. J. D. da Silva, T. H. Fares, H. C. D. de Souza","doi":"10.1249/01.mss.0000561508.53212.ea","DOIUrl":"https://doi.org/10.1249/01.mss.0000561508.53212.ea","url":null,"abstract":"OBJECTIVES\u0000We investigated the effects of early ovarian hormones deprivation on morphology and cardiac function and the effects of aerobic training on these parameters, in old rats.\u0000\u0000\u0000METHODS\u0000Female Wistar rats (N = 48) were divided into two groups, at 10 weeks of life: early ovarian hormones deprivation by ovariectomy (OVX; N = 24) and sham (SHAM; N = 24). Between weeks 62 and 82, 12 animals of each group underwent aerobic training (OVX-T and SHAM-T, N = 12). At the end of week 82, all were evaluated by echocardiography, cardiac function (Langendorff technique) and cardiac β-adrenergic receptor expression quantification.\u0000\u0000\u0000RESULTS\u0000Echocardiography showed slight changes in morphology between OVX and SHAM groups. OVX group (Δ = 101 ± 4.7 mmHg) showed higher values for maximal left intraventricular pressure in response to dobutamine, when compared to SHAM group (Δ = 55 ± 11.8 mmHg). Both OVX-T (Δ = 70 ± 4.0 mmHg) and SHAM-T (Δ = 22 ± 6.6 mmHg) groups showed a reduction in this response. While, β-adrenergic receptor expression was not different between the untrained groups, SHAM-T (0.23 ± 0.02 AU) and OVX-T (0.29 ± 0.01 AU), showed decreased expression of these receptors.\u0000\u0000\u0000CONCLUSION\u0000Early ovarian hormones deprivation associated with aging, promotes discrete changes in cardiac morphology and increasing cardiac contractility. Aerobic training decreases β-adrenergic receptors expression, influencing the cardiac contractility.","PeriodicalId":8666,"journal":{"name":"Autonomic Neuroscience","volume":"6 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79790709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Changes in excitability and ion channel expression in neurons of the major pelvic ganglion in female type II diabetic mice 雌性II型糖尿病小鼠盆腔神经节神经元兴奋性和离子通道表达的变化

Autonomic Neuroscience Pub Date : 2018-07-04 DOI: 10.1101/360826

Michael Gray, Kawasi M. Lett, V. B. Garcia, Cindy W. Kyi, K. Pennington, L. Schulz, D. Schulz

{"title":"Changes in excitability and ion channel expression in neurons of the major pelvic ganglion in female type II diabetic mice","authors":"Michael Gray, Kawasi M. Lett, V. B. Garcia, Cindy W. Kyi, K. Pennington, L. Schulz, D. Schulz","doi":"10.1101/360826","DOIUrl":"https://doi.org/10.1101/360826","url":null,"abstract":"Bladder cystopathy is a common urological complication of diabetes, and has been associated with changes in parasympathetic ganglionic transmission and some measures of neuronal excitability in male mice. To determine whether type II diabetes also impacts excitability of parasympathetic ganglionic neurons in females, we investigated neuronal excitability and firing properties, as well as underlying ion channel expression, in major pelvic ganglion (MPG) neurons in control, 10-week, and 21-week db/db mice. Type II diabetes in Leprdb/db animals caused a non-linear change in excitability and firing properties of MPG neurons. At 10 weeks, cells exhibited increased excitability as demonstrated by an increased likelihood of firing multiple spikes upon depolarization, decreased rebound spike latency, and overall narrower action potential half-widths as a result of increased depolarization and repolarization slopes. Conversely, at 21 weeks MPG neurons of db/db mice reversed these changes, with spiking patterns and action-potential properties largely returning to control levels. These changes are associated with numerous time-specific changes in calcium, sodium, and potassium channel subunit mRNA levels. However, Principal Components Analysis of channel expression patterns revealed that the rectification of excitability is not simply a return to control levels, but rather a distinct ion channel expression profile in 21-week db/db neurons. These data indicate that type II diabetes can impact the excitability of post-ganglionic, parasympathetic bladder-innervating neurons of female mice, and suggest that the non-linear progression of these properties with diabetes may be the result of compensatory changes in channel expression that act to rectify disrupted firing patterns of db/db MPG neurons.","PeriodicalId":8666,"journal":{"name":"Autonomic Neuroscience","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76812379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Alpha-Synuclein and Autonomic Neuropathy Progression in a Longitudinal Study of Parkinson’s Disease 帕金森病纵向研究中的α -突触核蛋白与自主神经病变进展

Autonomic Neuroscience Pub Date : 2015-11-30 DOI: 10.1016/j.autneu.2015.07.240

C. Gibbons, Ningshan Wang, Jenniffer Garcia, L. Shih, R. Freeman

引用次数: 1

Autonomic Heart Modulation in Chronic Kidney Disease 慢性肾脏疾病的自主心脏调节

Autonomic Neuroscience Pub Date : 2015-11-30 DOI: 10.1016/j.autneu.2015.07.084

F. R. Moraes, G. A. Galdino, G. V. Silva, A. Sant'Ana, M. Accioly

引用次数: 0

Smooth muscle-derived neurotrophins regulate development and function of vagal gastrointestinal (GI) afferents 平滑肌来源的神经营养因子调节迷走胃肠(GI)传入神经的发育和功能

Autonomic Neuroscience Pub Date : 2015-11-30 DOI: 10.1016/j.autneu.2015.07.017

E. Fox, J. Biddinger, J. McAdams

引用次数: 0