Atherosclerosis. Supplements最新文献

{"title":"Hypercholesterolemia and cardiovascular disease: Focus on high cardiovascular risk patients","authors":"Gerald F. Watts ,&nbsp;Alberico L. Catapano ,&nbsp;Luis Masana ,&nbsp;Alberto Zambon ,&nbsp;Angela Pirillo ,&nbsp;Lale Tokgözoğlu","doi":"10.1016/j.atherosclerosissup.2021.01.006","DOIUrl":"10.1016/j.atherosclerosissup.2021.01.006","url":null,"abstract":"<div><p>The widespread use of statins has largely improved the treatment of hypercholesterolemia, but many patients still fail to achieve the LDL-C targets recommended by guidelines. Furthermore, some patients continue to present a very high cardiovascular (CV) risk or even an extreme risk despite being well treated, mainly due to the presence of co-morbidities such as diabetes or peripheral artery disease, which significantly increase their global CV risk. For these very high CV risk patients, the most recent European guidelines have reviewed the LDL-C goals and recommend an LDL-C reduction of at least 50% and a goal of &lt;55 mg/dL or even &lt;40 mg/dL. Recent clinical trials have shown that patient stratification based on the presence or absence of atherothrombotic risk factors may represent a valuable tool to identify patients at extremely high CV risk who may benefit more from an aggressive LDL-C-lowering approach. In these patients it may be appropriate to aim for the lowest LDL-C level, independently of recommended goals, with all the available pharmacological approaches.</p></div>","PeriodicalId":8592,"journal":{"name":"Atherosclerosis. Supplements","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.atherosclerosissup.2021.01.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25375164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and relationship between metabolic syndrome and risk of cardiovascular disease: Evidence from two population-based studies","authors":"Asiiat S. Alieva ,&nbsp;Elena Olmastroni ,&nbsp;Olga V. Reutova ,&nbsp;Oxana P. Rotar ,&nbsp;Alexandra O. Konradi ,&nbsp;Evgeny V. Shlyakhto ,&nbsp;Andrea Baragetti ,&nbsp;Liliana Grigore ,&nbsp;Fabio Pellegatta ,&nbsp;Manuela Casula ,&nbsp;Elena Tragni ,&nbsp;Alberico L. Catapano","doi":"10.1016/j.atherosclerosissup.2021.01.008","DOIUrl":"10.1016/j.atherosclerosissup.2021.01.008","url":null,"abstract":"<div><h3>Background and aim</h3><p>The metabolic syndrome (MetS) has become one of the most important clinical issues in the cardiovascular field for this decade because of the marked increase in cardiovascular (CV) risk associated with a clustering of risk factors. The aim of the current study was to evaluate the relationship between MetS and its components and cardiovascular disease (CVD).</p></div><div><h3>Methods</h3><p>This population-based cross-sectional study was based on data from two studies carried out in Russia (ESSE-RF) and Italy (PLIC). One sample from each cohort was selected, matching individuals by sex and age. A comparison between samples of MetS components distribution and CV risk, according to SCORE chart, has been conducted.</p></div><div><h3>Results</h3><p>A total of 609 individuals (mean [SD] age 55 [8] years, about 39% males) for each cohort were selected. Almost half of PLIC cohort participants belonged to the moderate CV risk group (47% vs 27%), while in ESSE-RF cohort a relatively higher prevalence of individuals classified in the high and very high risk group was observed (19% vs 11%, 21% vs 6%, respectively). Overall, 43% of ESSE-RF participants were diagnosed with MetS, compared with the 27% of PLIC members (the difference in prevalence becomes 37% vs 21%, considering a more conservative cut-off for waist circumference). Both cohorts showed a trend towards the increase of MetS components moving from the lowest to the highest CV risk class, with a high prevalence of patients with four or five MetS determinants allocated in the high/very high CV risk group.</p></div><div><h3>Conclusions</h3><p>Developing effective public health strategies for the prevention, detection and treatment of MetS should be an urgent priority to reduce the burden of CVD, not only in subjects at high/very high CV risk, but also in those characterized by a lower risk, as even rare CV events that come from low risk group bring a tangible burden to healthcare systems.</p></div>","PeriodicalId":8592,"journal":{"name":"Atherosclerosis. Supplements","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.atherosclerosissup.2021.01.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25375166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipid Clinics Network. Rationale and design of the EAS global project","authors":"Asiiat S. Alieva ,&nbsp;Lale Tokgözoğlu ,&nbsp;Kausik K. Ray ,&nbsp;Alberico L. Catapano","doi":"10.1016/j.atherosclerosissup.2021.01.002","DOIUrl":"10.1016/j.atherosclerosissup.2021.01.002","url":null,"abstract":"<div><p>The evidence of the causal role of low-density lipoprotein cholesterol in the development of atherosclerotic cardiovascular disease is well-established. The clearly identified common position of the European guidelines proclaims necessity to decrease LDL-C concentrations based on a proper risk stratification. However, current worldwide situation with the lipid management still demonstrates inadequate dyslipidemia control, that is probably related to a healthcare system issues. As the need to standardize and implement approaches following the guidelines into clinical practice remains a challenge, the EAS initiates the <em>Lipid Clinics Network</em> project, aiming to provide a structure to establish uniform EU-wide standards of diagnosis, management and treatment of patients with lipid disorders, based on the ESC/EAS Guidelines on management of dyslipidaemias.</p></div>","PeriodicalId":8592,"journal":{"name":"Atherosclerosis. Supplements","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.atherosclerosissup.2021.01.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25370373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prevalence of cardiovascular risk factors and cardiovascular disease among primary care patients in Poland: results from the LIPIDOGRAM2015 study.","authors":"J. Jozwiak, Krzysztof Studziński, T. Tomasik, A. Windak, M. Mastej, A. Catapano, K. Ray, D. Mikhailidis, P. Toth, G. Howard, G. Lip, M. Tomaszewski, F. Charchar, N. Sattar, B. Williams, T. MacDonald, D. Nowak, Ł. Skowron, S. Kasperczyk, M. Banach","doi":"10.1093/ehjci/ehaa946.2847","DOIUrl":"https://doi.org/10.1093/ehjci/ehaa946.2847","url":null,"abstract":"BACKGROUND AND AIM\u0000To estimate the prevalence of cardiovascular (CV) disease and CV risk factors among Polish patients.\u0000\u0000\u0000METHODS\u0000A nationwide cross-sectional study, LIPIDOGRAM2015, was carried out in Poland in the 4th quarter of 2015 and 1st and 2nd quarters of 2016; 438 primary care physicians enrolled 13,724 adult patients that sought medical care in primary health care practices.\u0000\u0000\u0000RESULTS\u0000Nearly 19% of men and approximately 12% of women had cardiovascular disease (CVD). Over 60% of the recruited patients had hypertension (HTN), >80% had dyslipidaemia and <15% of patients were diagnosed with diabetes (DM). All of these disorders were more frequent in men. In 80% of patients the waist circumference exceed norm for the European population. Less than half of the patients were current smokers or had smoked in the past. Patients with CVD had significantly higher blood pressure and glucose levels but lower low density lipoprotein-cholesterol level.\u0000\u0000\u0000CONCLUSIONS\u0000The prevalence of CVD and CV risk factors among patients in Poland is high. CVD is more common in men than in women. The most common CV risk factors are excess waist circumference, dyslipidaemia and HTN. Family physicians should conduct activities to prevent, diagnose early and treat CVD in the primary health care population.","PeriodicalId":8592,"journal":{"name":"Atherosclerosis. Supplements","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84557244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics and Short Term Outcome of Multi-Vessel Coronary Artery Disease Patients Presented with AMI- Single Center Experience","authors":"Sheeren Mohammed Khaled","doi":"10.1016/j.atherosclerosissup.2020.01.005","DOIUrl":"10.1016/j.atherosclerosissup.2020.01.005","url":null,"abstract":"","PeriodicalId":8592,"journal":{"name":"Atherosclerosis. Supplements","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.atherosclerosissup.2020.01.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47103940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise-Based Cardiac Rehabilitation in Patients with Acute Coronary Syndrome","authors":"Noran Ibrahim ,&nbsp;Ikram Sadek ,&nbsp;Hanan Kassem ,&nbsp;Taimoor Mostafa","doi":"10.1016/j.atherosclerosissup.2020.01.009","DOIUrl":"10.1016/j.atherosclerosissup.2020.01.009","url":null,"abstract":"","PeriodicalId":8592,"journal":{"name":"Atherosclerosis. Supplements","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.atherosclerosissup.2020.01.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43724561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation Between Epicardial Fat Thickness Assessed by Echocardiography and Coronary Artery Disease Severity in Patients Attending Suez Canal University Hospital","authors":"Mahmoud S. Eisa,&nbsp;Mohamed A. Oraby,&nbsp;Ahmed H. Abdel Moneim,&nbsp;Ahmed S. Salem","doi":"10.1016/j.atherosclerosissup.2020.01.007","DOIUrl":"10.1016/j.atherosclerosissup.2020.01.007","url":null,"abstract":"","PeriodicalId":8592,"journal":{"name":"Atherosclerosis. Supplements","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.atherosclerosissup.2020.01.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46715837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ACS in CKD Patients","authors":"Tarek Mahmoud ,&nbsp;Ali Taha Ali ,&nbsp;Nayel Abdelhameed Zaki ,&nbsp;Sharaf Eldeen Shazli","doi":"10.1016/j.atherosclerosissup.2020.01.003","DOIUrl":"10.1016/j.atherosclerosissup.2020.01.003","url":null,"abstract":"","PeriodicalId":8592,"journal":{"name":"Atherosclerosis. Supplements","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.atherosclerosissup.2020.01.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45512361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in Early Invasive Management of Egyptian Patients with Acute Coronary Syndrome; Data from The Cross-Sectional Cardiorisk Project","authors":"Ashraf Reda ,&nbsp;Mohamed Ashraf ,&nbsp;Ahmed Bendary ,&nbsp;Ghada Kazamel ,&nbsp;Samir Rafla ,&nbsp;Mohamed Bendary ,&nbsp;Atef Elbahry ,&nbsp;Ahmed Shawky ,&nbsp;Osama Sanad ,&nbsp;Elsayed Farag ,&nbsp;Ahmed Elkersh ,&nbsp;Mourad Beshay ,&nbsp;Helmy Elghwaby ,&nbsp;Tamer Mustafa","doi":"10.1016/j.atherosclerosissup.2020.01.006","DOIUrl":"10.1016/j.atherosclerosissup.2020.01.006","url":null,"abstract":"","PeriodicalId":8592,"journal":{"name":"Atherosclerosis. Supplements","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.atherosclerosissup.2020.01.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47743214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Bilirubin as Predictor of Infarct-Related Artery Patency, and In-Hospital Outcomes for ST- Elevation Myocardial Infarction and In-Hospital Outcomes Following Percutaneous Coronary Intervention","authors":"Ashraf Reda ,&nbsp;Ashraf Ahmed Abdulmaged ,&nbsp;Ahmed Hassan Zaid","doi":"10.1016/j.atherosclerosissup.2020.01.010","DOIUrl":"10.1016/j.atherosclerosissup.2020.01.010","url":null,"abstract":"","PeriodicalId":8592,"journal":{"name":"Atherosclerosis. Supplements","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.atherosclerosissup.2020.01.010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41260482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}