Asian Journal of Pharmacy and Pharmacology最新文献_第2页

Development of reconstitutable nano-liposome of Ferrous Ascorbate for prophylaxis and treatment of iron deficiency anemia 抗坏血酸亚铁纳米脂质体预防和治疗缺铁性贫血的研究

Asian Journal of Pharmacy and Pharmacology Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.6.3

Sateesha S.B., Hirday Narayan Sah, Rajamma A.J.

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Evaluation of Anogeissus latifolia Roxb on complete freund’s adjuvant induced arthritis in albino rats 银杏对白化大鼠完全佐剂性关节炎的疗效评价

Asian Journal of Pharmacy and Pharmacology Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.3.2

P. Mumthaj, N. P

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A Retrospective study on Adverse Drug Reactions Monitoring and Reporting in a quaternary care super speciality hospital in Karnataka 卡纳塔克邦某四级特级专科医院药物不良反应监测与报告回顾性研究

Asian Journal of Pharmacy and Pharmacology Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.5.2

Puneeth G.K, Johncy Natasha, S. N, Kush Nimron

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A brief review on Pharmacological properties of Abutilon indicum roots 阿布蒂龙根的药理性质综述

Asian Journal of Pharmacy and Pharmacology Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.4.4

A. M. Krupanidhi, P. Dabadi, Chandana M., Mythree M.V., Pooja H. S., Pooja J. U., Sushma S.,, Sushruta K. H.

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Transmembrane passage of Sulfamethoxazole/Trimethoprim in combination with leaves extracts of Pseudocedrela kotschyi and Crossopteryx febrifuga 磺胺甲恶唑/甲氧苄啶与黄竹、凤尾鸟叶提取物联合的跨膜传代研究

Asian Journal of Pharmacy and Pharmacology Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.4.1

Thierry Lenoir Ayoman Djadji, É. Balayssac, Armelle Sandrine Aka-Any Grah, Nounaferitien Awa Silue, Gbongué Eric Tia, Sylvain Landry Kouakoa, Gisèle N'doua Siranst-Kouakou

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A comparative assessment of antidiabetic drug usage and related pharmaceutical care issues between Geriatric and non-Geriatric population in teaching hospital 教学医院老年与非老年人群抗糖尿病药物使用及相关药学服务问题的比较分析

Asian Journal of Pharmacy and Pharmacology Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.2.3

R. G. Raj, J. Benny, A. Siddiq, Shethal Saji, S. P

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Assessment of anti-obesity activity of Tamarindus leaves on butter induced hyperlipidemia in mice 柽柳叶对牛油致高脂血症小鼠抗肥胖作用的研究

Asian Journal of Pharmacy and Pharmacology Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.3.5

Geetha Rani Valaparla, Gutta Vishnu Sai, D. Kumar

{"title":"Assessment of anti-obesity activity of Tamarindus leaves on butter induced hyperlipidemia in mice","authors":"Geetha Rani Valaparla, Gutta Vishnu Sai, D. Kumar","doi":"10.31024/ajpp.2022.8.3.5","DOIUrl":"https://doi.org/10.31024/ajpp.2022.8.3.5","url":null,"abstract":"Objective: Obesity is one of the world's leading problems, which is major cause of Cardiovascular Diseases. During COVID - 19 pandemic many young children and all age group people are getting challenged by obesity due stagnant life style. To treat such life threatening disorder natural remedies acquire prior position, Plant produce a good deal of secondary metabolites which have a beneﬁted mankind in various ways, including treatment of diseases The present research work was focused on developing a natural remedy using an ancient plant with number of Tamarindus indica, proven activities in Traditional medicine. In the literature survey, it was found that Materials and Methods: ﬂavonoids, sterols, tannins and alkaloids shown promising eﬀects to tackle obesity by various mechanisms, Tamarindus indica has shown the presence of saponins, ﬂavonoids, glycosides, amino acids, alkaloids. With the above evidence, this plant has been selected for screening of its antiobesity activity against high fat diet induced obesity in mice. Studies were conducted using aqueous extract of leaves (AETI) on high fat diet (butter) Tamarindus indica induced model of hyperlipidemia in mice. During 21 days time period AETI low and high Results and Discussion: doses were induced to respective animal groups along with butter where Atorvastatin has been taken as standard drug. Butter enhanced the Cholesterol and triglyceride, LDL levels. At the end of 21 days blood samples were collected from the animal through retroperitoneal route. Biochemical parameters of AETI have been revealed its antiobesity activity. high fat antiobesity, Atorvastatin","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80462275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microbial load and O157:H7, cp5, cp8 Serotypes assessment of some non-sterile pharmaceutical drug types sold at major outlets in Lafia, Nigeria 尼日利亚拉菲亚主要销售点销售的一些非无菌药品类型的微生物负荷和O157:H7、cp5、cp8血清型评估

Asian Journal of Pharmacy and Pharmacology Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.3.4

J. Nfongeh, Dauda Anoh Hashimu, D. D. Odonye͙͙͙͙͙, Adamu Abisabo, Aminu Kazeem Fauzeeyah, A. Kabiru

{"title":"Microbial load and O157:H7, cp5, cp8 Serotypes assessment of some non-sterile pharmaceutical drug types sold at major outlets in Lafia, Nigeria","authors":"J. Nfongeh, Dauda Anoh Hashimu, D. D. Odonye͙͙͙͙͙, Adamu Abisabo, Aminu Kazeem Fauzeeyah, A. Kabiru","doi":"10.31024/ajpp.2022.8.3.4","DOIUrl":"https://doi.org/10.31024/ajpp.2022.8.3.4","url":null,"abstract":"Objective: Non-sterile pharmaceutical products are usually subjected to unrestricted handling and are therefore potentially susceptible to postproduction contamination by microorganisms from both handlers and the environment. This study was carried out to determine the microbial quality of some commonly administered non-sterile drug types from hawkers and pharmacy outlets within Laﬁa Metropolis, Nigeria. : A total of 240 samples Material and methods (80 samples each of tablets, syrups and ointments) were purchased from pharmacies and hawkers' outlets and the microbial load determined using the W.H.O Pharmacopoeia and serological methods. From Results and conclusion: this study, the mean Total Aerobic Bacterial Counts (TABC) and the Mean Total Yeast and Mold Counts (TYMC) had values higher than the W.H.O recommended levels for some syrups and tablets from both pharmacy and hawkers' outlets. The diﬀerence in the values among the various outlets and between the drug types were statistically signiﬁcant at p<0.05. Results of immunoassay indicated that was isolated from 23/120 (19.17%) hawkers' drugs among E. coli which 1/23 (4.35%) was the O157:H7serotype. Similarly, 17/120 (14.17%) hawkers' drugs had Staphylococcus aureus among which 8/17(47.06%) and 6/17(35.27%) were and serotypes respectively while 3/17(17.65%) had no cp5 cp8 capsular antigen ( ). These values were signiﬁcantly higher (p<0.05) than those obtained from pharmacy outlets. The cp-microbial qualities of most of the pharmacy products were in accordance with International Pharmacopoeia while some, especially the tablets and syrups from hawkers, exceeded the recommended acceptance limit and might be of health risks to consumers.","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75788404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Usnic acid: A promising bioactive agent for wound healing Usnic酸:一种很有前途的伤口愈合生物活性剂

Asian Journal of Pharmacy and Pharmacology Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.6.4

A. Shukla, M. Nireekshan Kumar, M. Sharma, S. K. Dev, Rahul Maurya

引用次数: 0

Protein and peptide drug delivery system: A brief review 蛋白质和多肽药物传递系统:综述

Asian Journal of Pharmacy and Pharmacology Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.3.1

V. Nikam, S. Suryawanshi, Jyoti Khapare

{"title":"Protein and peptide drug delivery system: A brief review","authors":"V. Nikam, S. Suryawanshi, Jyoti Khapare","doi":"10.31024/ajpp.2022.8.3.1","DOIUrl":"https://doi.org/10.31024/ajpp.2022.8.3.1","url":null,"abstract":"The protein and Peptide delivery system is the Novel drug Delivery System. Proteins and peptides are the most abundant components of living cells. There are those that act as enzymes, hormones, structural element and immunoglobulin. Twenty diﬀerent naturally occurring amino acids combine with each other through peptide bonds and form polymers targeting peptides and proteins. Although the diﬀerence between peptides and proteins in peptide contains less than 20 amino acids, they have a molecular weight of less than 5000, while the protein has 50 amino acids or more and its molecular weight is above this value. Most pharmaceutical proteins and peptides are absorbed by IM, IV and the Subcutaneous route of Absorption, but the oral route is better absorbed by protein compared to another. Various problems associated with protein and peptide drug administration are needed to overcome various drug regimens. A few ways available to increase pharmacokinetic and pharmacodynamics properties are chemical modiﬁcation, construction vehicles, mucoadhesive polymeric system, use of enzyme inhibitors, absorption enhancers, inﬁltration enhancers etc. Current review deﬁnes structure, protein separation, need, beneﬁts, protein function and peptide drug delivery system.","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90325224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0