Problemy tuberkuleza i boleznei legkikh最新文献_第4页

[Topical problems of antituberculosis care to children and adolescents]. 儿童和青少年抗结核护理的局部问题。

Problemy tuberkuleza i boleznei legkikh Pub Date : 2009-01-01

E S Obsiankina

引用次数: 0

[Prediction of infiltrative pulmonary tuberculosis outcomes depending on the procedure of its detection and on the manifestation of clinical and x-ray symptoms]. [浸润性肺结核预后的预测取决于其检测程序和临床及x线症状的表现]。

Problemy tuberkuleza i boleznei legkikh Pub Date : 2009-01-01

I A Volchegorskiĭ, P N Novoselov, A A Bolotov

引用次数: 0

[Trends in major tuberculosis epidemiological indices in Armenia over 10 years (1997-2006)]. [亚美尼亚10年来主要结核病流行病学指数趋势(1997-2006年)]。

Problemy tuberkuleza i boleznei legkikh Pub Date : 2009-01-01

M D Safarian, E P Stamboltsian, D A Arutiunian

{"title":"[Trends in major tuberculosis epidemiological indices in Armenia over 10 years (1997-2006)].","authors":"M D Safarian, E P Stamboltsian, D A Arutiunian","doi":"","DOIUrl":"","url":null,"abstract":"The authors studied statistical data on the trend in quantitative and qualitative tuberculosis epidemiological indices in Armenia in the period of 1997 to 2006. They ascertained a 1.7-fold rise in the incidence and prevalence of tuberculosis per 100,000 (from 27.8 to 48.6 and from 103.8 to 176.1), by preserving the mortality rates at the same level (4.3). However, morbidity rates have become steady-state in the past 2 years. Along with this, that was a slight deterioration in the qualitative indices--new tuberculosis cases showed increases in the proportion of destructive forms from 62.9 to 67.7%, bacteria-discharging persons from 70 to 75.9%, extrapulmonary forms from 7.3 to 9.3%, childhood morbidity from 9.6 to 19.1% with reductions in their proportion among all detected patients from 12.2 to 9.9%; an increase in the proportion of deceased persons within the first year of the disease from 20.6 to 35.0% and in postmortem diagnosis rates from 0.7 to 0.8%. The cure rates comprised an increase in cavern closure rates from 55.4 to 66%, with the preservation of bacterial discharge cessation at the level of 73-74%, a reduction in mortality rates among both new cases from 3.5 to 2.5 and the contingent of tuberculosis patients from 4.8 to 3.5%, a 3.3-fold rise in early recurrences (from 0.9 to 1.3 per 100,000). The further task of the republic's antituberculosis service, planned by the authors, is to improve work in actively detecting tuberculosis in risk groups and treatment monitoring in patients with tuberculosis.","PeriodicalId":85348,"journal":{"name":"Problemy tuberkuleza i boleznei legkikh","volume":" 2","pages":"32-7"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28122112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Evaluation of hepatic function in new cases of pulmonary tuberculosis due to the use of standard chemotherapy regimens I and IIB]. [标准化疗方案I和IIB对新发肺结核患者肝功能的评价]。

Problemy tuberkuleza i boleznei legkikh Pub Date : 2009-01-01

R Iu Abdullaev, E V Vaniev, G O Kaminskaia, I A Vasil'eva, O G Komissarova

{"title":"[Evaluation of hepatic function in new cases of pulmonary tuberculosis due to the use of standard chemotherapy regimens I and IIB].","authors":"R Iu Abdullaev, E V Vaniev, G O Kaminskaia, I A Vasil'eva, O G Komissarova","doi":"","DOIUrl":"","url":null,"abstract":"The frequency and magnitude of hepatotoxic reactions were compared in 147 new cases of pulmonary tuberculosis within the first three months of chemotherapy (CT) by standard regimen 1 [H, R, Z, S (E)] (Group 1) and regimen 2B [the same drugs + kanamycin (amikacin) and fluoroquinolones] (Group 2). Their efficiency was evaluated from 6 serum indices--the level of bilirubin, the activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (AP), and gamma-glutamyl transpeptidase (GGTP), and thymol test results. Tests were monthly carried out. The results were separately analyzed in patients with and without baseline abnormalities in the indices being tested. Within the first two months of CT, the patients without baseline abnormalities showed the slightly higher frequency and magnitude of hepatotoxic reactions on receiving regimen 2B. Following 3 months of CT combined with hepatoprotectors, the patients treated by standard regimen 1 had solitary laboratory signs of hepatic damage, but there was a regular elevation of GGTP in the regimen 2B group. After a month of regimen 1 CT in combination with hepatoprotectors, the patients with baseline abnormalities has positive changes in all the studied indices. In the patients treated by regimen 2B in combination with hepatoprotectors, the changes were the same, except for GGTP that remained to be at the increased baseline levels. Following 2 months of CT, in Group 1 positive changes continued in the studied markers and, with regimen 2B treatment, abnormal changes began increasing again. After 3 months abnormal changes were single in the markers of hepatic damage with regimen 1 treatment and there was a repeated significant rise in the values of AP and GGTP with regimen 2B. It is concluded that in addition to ALT and AST, GGTP is of great informative value in controlling the hepatotoxic effects of CT.","PeriodicalId":85348,"journal":{"name":"Problemy tuberkuleza i boleznei legkikh","volume":" 2","pages":"57-61"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28122117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Pulmonary tuberculosis and cancer]. [肺结核和癌症]。

Problemy tuberkuleza i boleznei legkikh Pub Date : 2009-01-01

A A Sadovnikov, K I Panchenko

引用次数: 0

[Antituberculosis humoral immunity in patients with tuberculosis, HIV infection concurrent with tuberculoses]. [结核病患者的抗结核体液免疫，艾滋病毒感染合并结核病]。

Problemy tuberkuleza i boleznei legkikh Pub Date : 2009-01-01

I M Khaertynova, A P Tsybul'kin, R Sh Valiev, G A Idiiatullina, S E Romanenko

引用次数: 0

[Clinical and immunological features of concomitant HIV/tuberculosis infection and HIV infection without tuberculosis]. 【伴发性HIV/结核感染与非结核性HIV感染的临床及免疫学特点】。

Problemy tuberkuleza i boleznei legkikh Pub Date : 2009-01-01

I M Khaertynova, R Sh Valiev, A P Tsibul'kin, N R Valiev, R V Khamzina, O G Lazarenko, S E Romanenko