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Bioelectric Medicine: Magicall Tools for Treatment of Many Diseases 生物电医学:治疗多种疾病的神奇工具
Asian Journal of Pharmacy and Technology Pub Date : 2021-11-26 DOI: 10.52711/2231-5713.2021.00052
Vikram B. Madane, S. N. Mali
{"title":"Bioelectric Medicine: Magicall Tools for Treatment of Many Diseases","authors":"Vikram B. Madane, S. N. Mali","doi":"10.52711/2231-5713.2021.00052","DOIUrl":"https://doi.org/10.52711/2231-5713.2021.00052","url":null,"abstract":"Bioelectronic medicine is a relatively new area that focuses on developing methods for treating diseases that do not need medications. Bioelectronic medicine treatments are now possible thanks to a small embedded system that produces and delivers frequent digital doses to nerve bundles, resulting in a disease-fighting effect that can last hours or days and is based on mechanisms similar to drug therapies. Although this may sound like science fiction, electronic brain and nerve stimulators are now presence applicable to treat so many of ailments, including epilepsy, Parkinson's disease, and bladder control. Progress in treating such disorders has opened up possibilities for boosting memory, improving eyesight, strengthening a shaky gait, and even improving a golfer's swing. Those self-improvement dreams may be a long way off, but bioelectronic medicine is gaining traction as a new way to treat difficult diseases. What distinguishes bioelectronic medicine is its biological effect on the body, which goes beyond symptom management to treat the underlying condition by using the body's own mechanisms. With promising early results in many trials and further trials ongoing, bioelectronic therapies are likely to be accepted for clinical use within the next few years. To make this advancement possible, forward-thinking scientists, engineers, doctors, and innovators with specialised talents combined old and new discoveries in ways no one had before.","PeriodicalId":8527,"journal":{"name":"Asian Journal of Pharmacy and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80367718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Short Review on Nasal Drug Delivery System 鼻腔给药系统研究进展综述
Asian Journal of Pharmacy and Technology Pub Date : 2021-11-26 DOI: 10.52711/2231-5713.2021.00048
Akash H. Mali, Azam Z. Shaikh
{"title":"A Short Review on Nasal Drug Delivery System","authors":"Akash H. Mali, Azam Z. Shaikh","doi":"10.52711/2231-5713.2021.00048","DOIUrl":"https://doi.org/10.52711/2231-5713.2021.00048","url":null,"abstract":"Nasal drug delivery has received a great deal of attention as convenient, reliable and promising methods for the systemic administration of drug. It is especially for those molecules which are ineffective oraly and only effective if administration by injection. The nasal route of drug delivery has advantage over the other alternative system of drug administration. The present review is an attempt to provide some information concerning nasal drug delivery system such as limitation, advantage, mechanism drug absorption, anatomy and Physiology Nasal, factor affecting of nasal drug delivery, drug distribution and deposition, Challenges and oppurtunities for Nasal Delivery Systems1. These drug delivery system have the ability to control the rate of drug clearance from the nasal cavity as well as protect the drug from enzymatic degradation in nasal secretions2..","PeriodicalId":8527,"journal":{"name":"Asian Journal of Pharmacy and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74955871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Short Review on Novel Dosage Form 新剂型综述
Asian Journal of Pharmacy and Technology Pub Date : 2021-11-26 DOI: 10.52711/2231-5713.2021.00051
T. N. Sonawane, Pradip D. Dhangar, Sagar D Patil, Azam Z. Shaikh
{"title":"Short Review on Novel Dosage Form","authors":"T. N. Sonawane, Pradip D. Dhangar, Sagar D Patil, Azam Z. Shaikh","doi":"10.52711/2231-5713.2021.00051","DOIUrl":"https://doi.org/10.52711/2231-5713.2021.00051","url":null,"abstract":"Novel Drug Delivery Systems are one of the widely use delivery system in the presence scenario. Novel drug delivery system is a novel approach to drug delivery that addresses the limitations of the traditional drug delivery systems. In the form of a Novel Drug Delivery System an existing drug molecule can get a new life. The novel drug delivery system is Increases bioavailability and it Can be used for long-term treatments of chronic illness, Sustained maintenance of plasma drug levels as well as it Decreased adverse drug effects in the total amount of drugs required thus reducing side effects it Improved patient compliance due to reduction in number and frequency of doses required. There is less damage sustained by normal tissue due to targeted drug delivery. In this paper our main focus to give the throughout knowledge of some newer (Novel drug delivery system) to understand the concept of the Novel dossage form.","PeriodicalId":8527,"journal":{"name":"Asian Journal of Pharmacy and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74822537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanotechnology: Overview and its application 纳米技术:概述及其应用
Asian Journal of Pharmacy and Technology Pub Date : 2021-11-26 DOI: 10.52711/2231-5713.2021.00049
Amit Nikam, A. Patil, C. Magdum
{"title":"Nanotechnology: Overview and its application","authors":"Amit Nikam, A. Patil, C. Magdum","doi":"10.52711/2231-5713.2021.00049","DOIUrl":"https://doi.org/10.52711/2231-5713.2021.00049","url":null,"abstract":"The study of different microscopic or tiny shaped and sized particles is what nanotechnology is all about. These nano-structured compounds have a wide range of strong actions in a variety of disciplines. These are readily carried due to their small size and form. Because of its small size, it may be used in a variety of ways. Nanotechnology improves a variety of businesses, including the pharmaceutical industry, the food industry, environmental protection, and a variety of others. The purpose of this article is to provide an overview of nanotechnology and its applications in different industries and areas.","PeriodicalId":8527,"journal":{"name":"Asian Journal of Pharmacy and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91290313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Formulation and Evaluation of Mucoadhesive Buccal Tablets of Anti-Diabetic Drug using 23 Factorial Design 采用23因子设计对抗糖尿病药黏附含片的处方及评价
Asian Journal of Pharmacy and Technology Pub Date : 2021-11-26 DOI: 10.52711/2231-5713.2021.00043
P. Nagaveni, Sirisha. S, C. A. Rao
{"title":"Formulation and Evaluation of Mucoadhesive Buccal Tablets of \u0000Anti-Diabetic Drug using 23 Factorial Design","authors":"P. Nagaveni, Sirisha. S, C. A. Rao","doi":"10.52711/2231-5713.2021.00043","DOIUrl":"https://doi.org/10.52711/2231-5713.2021.00043","url":null,"abstract":"The aim of the present study involved the formulation and evaluation of mucoadhesive buccal tablets of anti-diabetic drug gliclazide, Mucoadhesive buccal tablets of Gliclazide are prepared by direct compression method In this present investigational research work the mucoadhesive buccal tablets of gliclazide is prepared separately employing 23 randomized full factorial design by using xanthan gum, carbopol-934, HPMC-E15LV, In this experimental model, target is to determine how the t90% of drug release and mucoadhesive characters can be affected by adjusting three parameters, concentration of polymers xanthan gum, HPMC-E15LV, carbopol-934, of the mucoadhesive buccal tablets. 2 3 full factorial studies were designed to determine the interaction of three independent variables at two levels (low and high level concentration) The tablets were tested for weight variation, hardness, surface pH, drug content uniformity, swelling index, mucoadhesion strength and in-vitro drug release study, Ex- vivo mucoadhesion time. From the drug release studies it was found that formulation H4 containing has good drug release when compared to other formulations.","PeriodicalId":8527,"journal":{"name":"Asian Journal of Pharmacy and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83866199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Babchi (Psoralea corylifolia): From a Variety of Traditional Medicinal Application to its Novel Roles in Various Diseases: A Review 补骨脂(Psoralea corylifolia):从多种传统医学应用到其在各种疾病中的新作用:综述
Asian Journal of Pharmacy and Technology Pub Date : 2021-08-14 DOI: 10.52711/2231-5713.2021.00039
Habeeba Shaikh, Siddiqua Shaikh
{"title":"Babchi (Psoralea corylifolia): From a Variety of Traditional Medicinal Application to its Novel Roles in Various Diseases: A Review","authors":"Habeeba Shaikh, Siddiqua Shaikh","doi":"10.52711/2231-5713.2021.00039","DOIUrl":"https://doi.org/10.52711/2231-5713.2021.00039","url":null,"abstract":"Psoralea corylifolia (Leguminosae) commonly known as babchi or babachi has been used in different traditional system of various aliments since, ancient time. Psoralea corylifolia grow throughout Asia and India or many other countries. This article aims to provide a comprehensive review on the phytochemical and pharmacological aspect of Psoralea corylifolia. In traditional medicine, it has been used in treatment of various diseases such as leucoderma skin diseases, cardiovascular diseases, nephritis, osteoporosis, and cancer vitiligo, poisoning, for conception, caries, deafness, filarial. The stem, seeds, leaves, of this plant containe a variety of biologically active compound such as flavonoids, coumarins, phenols, benzofurans, benzopyrans, quinines, sesquiterpenoids, triterpenoids, steroids, and some other components. Those have varuous medicinal properties. The different part of the plant showed the antimicrobial, antipregnancy, estrogenic, antitumor, antioxidant, and many other pharmacological activities. The article focus on traditional as well as modern use and various activities of the plant.","PeriodicalId":8527,"journal":{"name":"Asian Journal of Pharmacy and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81175129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Studies on properties of Novel natural disintegrant after processing of Spray dried and Freez dried technique 新型天然崩解剂喷雾干燥和冷冻干燥后的性能研究
Asian Journal of Pharmacy and Technology Pub Date : 2021-08-14 DOI: 10.52711/2231-5713.2021.00041
Khairnar Suhas Kishor, Shadab Husain Ashfaque Husain, Patil Pooja Ravsaheb, Gangurde A.B, V. Bairagi
{"title":"Studies on properties of Novel natural disintegrant after processing of Spray dried and Freez dried technique","authors":"Khairnar Suhas Kishor, Shadab Husain Ashfaque Husain, Patil Pooja Ravsaheb, Gangurde A.B, V. Bairagi","doi":"10.52711/2231-5713.2021.00041","DOIUrl":"https://doi.org/10.52711/2231-5713.2021.00041","url":null,"abstract":"Natural disintegrant are widely used in the development of mouth dissolving tablets and other formulation because of easily available, low cost and rapide onset of action in the mouth dissolving tablet and it enhance the bioavalaibility and disintegration properties as comparaed to synthetic polymer. But aftrer freeze drying and spray drying technique the properties of dsintegrant is increases because its improve the bulkiness and flow property of a powder such as bulk density, tapped density, angle of repose, hausner raio, carrs index etc. by freeze drying the powder are dried and thereby increase the dissolution and disintegration time and highly porous powder is produced by spray drying technique.","PeriodicalId":8527,"journal":{"name":"Asian Journal of Pharmacy and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85098000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Formulation development of Temozolomide liposomal formulation in the treatment of Glioma 替莫唑胺脂质体制剂治疗胶质瘤的研制
Asian Journal of Pharmacy and Technology Pub Date : 2021-08-14 DOI: 10.52711/2231-5713.2021.00033
S. Velivela, N. B. Pati, B. R. Babu
{"title":"Formulation development of Temozolomide liposomal formulation in the treatment of Glioma","authors":"S. Velivela, N. B. Pati, B. R. Babu","doi":"10.52711/2231-5713.2021.00033","DOIUrl":"https://doi.org/10.52711/2231-5713.2021.00033","url":null,"abstract":"Temozolomide is an anti-cancer drug; it was encapsulated in liposomal intravenous application. To avoid the side effects and to target the drug to the specific site, we have formulated liposomal formulation of Temozolomide. The liposomal were prepared by dried thin film hydration technique using rotary evaporator with drug and Soya phosphatidyl choline as carrier. The prepared liposomes were characterized for size, shape, % entrapment efficiency, in-vitro drug release and physical stability. The evaluated batches showed good physicochemical characteristics. The maximum encapsulation efficiency of Temozolomide was achieved with formulation TMZ 6 with 40.19% and the in-vitro drug release is 64.94%. Based on the results it can be concluded that TMZ 6 was selected as optimized formulation and the optimized formulation Optimized formulation follows zero order release kinetics and follow super case II transport when it applied to Korsmeyer-Pepps model for mechanism of drug release.","PeriodicalId":8527,"journal":{"name":"Asian Journal of Pharmacy and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88426492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Formulation and Evaluation of Transdermal Patches of Benidipine Hydrochloride 盐酸苯地平透皮贴剂的研制及评价
Asian Journal of Pharmacy and Technology Pub Date : 2021-08-14 DOI: 10.52711/2231-5713.2021.00034
K. Gajbhiye, Nawaz Hakam, Gauri Rathod, M. Tawar
{"title":"Formulation and Evaluation of Transdermal Patches of Benidipine Hydrochloride","authors":"K. Gajbhiye, Nawaz Hakam, Gauri Rathod, M. Tawar","doi":"10.52711/2231-5713.2021.00034","DOIUrl":"https://doi.org/10.52711/2231-5713.2021.00034","url":null,"abstract":"The present research was designed to evaluate matrix type Benidipine Hydrochloride transdermal patches. So, the present work is an attempt to study effect of variation in Methocel E15LV concentration and study effect of hydrophilic and hydrophobic Methocel E15LV and Eudragit RL100 combination on release profile of Benidipine Hydrochloride. All prepared formulations were evaluated for physical and mechanical properties like thickness, moisture uptake, percent flatness, tensile strength, and percent elongation. An attempt was made to get a patch with suitable drug release property as well as physical and mechanical properties. A formulation containing Methocel E15LV 2% has shown good physical, mechanical and in-vitro drug release properties. It also showed good diffusion of Benidipine Hydrochloride across goat skin.","PeriodicalId":8527,"journal":{"name":"Asian Journal of Pharmacy and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91246559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Formulation, Optimitziation and Evaluation of Polyherbal Anti-Dandruff Shampoo 复方去屑洗发水的配方、优化及评价
Asian Journal of Pharmacy and Technology Pub Date : 2021-08-14 DOI: 10.52711/2231-5713.2021.00036
Arpit Gawshinde, D. Mishra, Neha Kamalpuria, N. Farooqui, Surbhi Choursiya
{"title":"Formulation, Optimitziation and Evaluation of Polyherbal Anti-Dandruff Shampoo","authors":"Arpit Gawshinde, D. Mishra, Neha Kamalpuria, N. Farooqui, Surbhi Choursiya","doi":"10.52711/2231-5713.2021.00036","DOIUrl":"https://doi.org/10.52711/2231-5713.2021.00036","url":null,"abstract":"Psidium Guajava, family Myrtaceae and Glycyrrhiza glabra family Leguminosae has been reported to possess antioxidant, antimicrobial, antiinflammatory, antibacterial and antifungal properties. Gauva and Liquiorice extracts have been used to treat antimicrobial infections. It contain several chemicals compound such as flavonoids, tannins, phenols, triterpenes, saponins, to take the benefit of the nature of extract. Psidium Guajava and Glycyrrhiza glabra prepare shampoo incorporating in the herbal constituent base and evaluate this natural herbal shampoo. The herbal shampoo formulations comprising of hydroalcoholic extract of Psidium Guajava and Glycyrrhiza glabra (ethanol:water 80:20v/v), coconut oil, castor oil, cymbopogon citrates oil were prepared and evaluated for physicochemical parameters such as visual appearance, pH, viscosity, % of solids content, foaming capacity and the results showed that the formulation F4 of anti-dandruff herbal shampoo contains all good characters of an ideal shampoo and it was found to be harmless, more effective, ease of manufacturing and economical compared to synthetic antidandruff shampoo.","PeriodicalId":8527,"journal":{"name":"Asian Journal of Pharmacy and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73941860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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