I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]最新文献

{"title":"18-FDG PET-CAT scan detection of unknown primary tumor. A case report.","authors":"G Menaldo, D Rubello, S Toso, V Migliorini, M A Ravasi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S168"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25821463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Total gastrectomy for gastric cancer: can the type of lymphadenectomy condition the long-term results?].","authors":"N Di Martino,&nbsp;G Izzo,&nbsp;A Cosenza,&nbsp;L Vicenzo,&nbsp;L Monaco,&nbsp;F Torelli,&nbsp;A Basciotti,&nbsp;A Brillantino,&nbsp;A Marra","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Gastric cancer is the second tumor for frequency in the world. Surgery is still the only curative treatment. Good results in terms of long distance survival, postoperative morbidity and mortality have been achieved in the last years. The extension of lymphadenectomy is an important and discussed matter and it is not clear if lymphadenectomy may contribute to improve the surgical results. The Japanese surgeons were the first ones, in the 60's, to introduce a D2-D3 extended lymphadenectomy, but the real benefits of this technique are still being discussed. Indeed lymphonodal metastasis seem to be one of the most important prognostic factors in the gastric cancer and the level and the number of metastatic nodes are useful to predict the patients' survival. The aim of this study is to value the D2 lymphadenectomy in the patients who were treated with total gastrectomy for gastric adenocarcinoma, comparing the results both with the D1 lymphadenectomy and the D3-D4, paying attention to the survival rates related with the lymphonodal dissection.</p><p><strong>Patients and method: </strong>From 1998 to 2004, we studied 87 patients with gastric cancer. Out of 78 patients treated surgically, 9 were judged unresectable. Out of 69 patients treated surgically, one died before surgery and so he was put away by this study. All the patients were treated with total gastrectomy and a GI tract reconstruction by Roux's Y termino-lateral esophageal-jejunal anastomosis. In 20 patients we also made a splenectomy. We followed the Japanese Research Society for Gastric Cancer guidelines, according to which nodes are gathered into 16 levels and divided in 4 groups (N1-N4) depending on the cancer localization. The extension of the lymphadenectomy has been classified according to the level of the removed nods. The patients were divided into 3 groups. First group: patients undergone a total gastrectomy with D1 lymphadenectomy. Second group: patients undergone D2 lymphadenectomy. Third group: patients undergone D3 and D4 lymphadenectomy. The data we obtained let us value the survival rate.</p><p><strong>Results: </strong>Out of the 78 patients treated, 69 were resected with a 88.5% resection rate (69/78). Perioperatory mortality was 1.4% (1/69). Global survival was 53.8% (44/68). The 5 years survival for the Ia stage was 82.6%, 89.3% for the Ib stage, 67.8% for the II stage, 56.6% for the IIIa, 16.8% for the IIIb and 0% for the IV stage. In addition the 5 years survival in the patients without lymphnodal metastasis was 79%, much higher than the 30.6% obtained in the patients with lymphonodal metastasis (p <0.0001). In the patients who underwent D1 lymphadenectomy, survival was 73.4%, while we obtained a result of 70.4% and 13.8% respectively in the D2 and D3-D4 (p <0.05). In the advanced stages (IIIa, IIIb, IV), the survival rate in the patients with lymphadenectomy D2 vs D1 vs D3-D4 was 38.9% vs 0% vs 36.3% (p <0.0001). The survival rate base","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S84-5"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25821710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Surgical resection of gastrointestinal stromal tumor after treatment with imatinib: clinical case].","authors":"S Baldo,&nbsp;M Rivoire,&nbsp;A Sobrero,&nbsp;D Comandini,&nbsp;D Civalleri,&nbsp;M Stella,&nbsp;F Quaglia,&nbsp;R Santoni,&nbsp;M Malerba,&nbsp;F Mariani,&nbsp;F DeCian","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The stromal tumor is the most common mesenchymal tumor of the gastrointestinal tract. Surgical resection is the first-line therapy for operable lesions, however for inoperable imatinib is an effective therapy. In this setting a patient has been operated after a remarkable response to imatinib, used as both neoadjuvant and adjuvant. This approach led to a disease-free condition without toxicity and complications.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S97"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25821715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Five hundred sixty-nine flaps used in reconstruction of the head and neck: morbidity analysis and results].","authors":"G Caravelli,&nbsp;L Lorenzon,&nbsp;F Arelli,&nbsp;G Cricrì,&nbsp;F Marcasciano,&nbsp;S Pompei","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Aim of the study is to provide high-level results in terms of functionality and softness of the tissues achieved with different reconstructive techniques performed in oncological surgery of the head and neck. Test group was composed of 528 patients recovered with a diagnosis of head and neck cancer. We performed 569 flaps: myocutaneous, cutaneous and fasciocutaneous, and free flaps. The clinical outcome and the morpho-functional evaluation show that free flaps can ensure excellent results, especially in defined anatomical areas such as the cervical-esophageal region, jaw and tongue. As to myocutaneous and cutaneous/fasciocutaneous flaps, they are still the first reconstructive choice, according to their minimal or no functional implications.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S186-7"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25821896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Duodenocephalopancreatectomy for periampullary neoplasm in elderly patients].","authors":"A Antinori,&nbsp;L Ciccoritti,&nbsp;C Coco,&nbsp;F Giuliante,&nbsp;P Magistrelli,&nbsp;G Nuzzo,&nbsp;A Picciocchi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>As life expectancy continue to increase, many elderly patients may be considered for pancreaticoduodenal resection. The purpose of the study was to review our experience with pancreatic resection for periampullary evaluating immediate and long-term results in patients aged 75 or older.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S58"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25822101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-stage treatment in emergency setting for obstructing colorectal cancer.","authors":"A Pisanu,&nbsp;A Montisci,&nbsp;N Cillara,&nbsp;P Ongetta,&nbsp;A Uccheddu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this study was to evaluate the indications for one-stage treatment of obstructing colorectal cancer. From January 1998 to December 2003, 19 patients were operated on at our department for obstructing colorectal cancer. Thirteen patients underwent one-stage operation with immediate anastomosis without diversion, while 6 patients were managed palliatively. We performed resection and anastomosis following intraoperative irrigation in obstructing sigmoid cancer without colonic wall lesions, while subtotal colectomy was carried out in case of massively distended colon with ischemic lesions. Colostomy was indicated in 6 high-risk patients with unresectable lesions. In case of obstructing left colorectal cancer, an experienced surgeon can perform one-stage resection and anastomosis on good general status patients, conversely defunctioning colostomy may be ideal for surgeons with little experience in colorectal surgery and in very poor prognosis patients.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S148"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25822112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Reconstruction with skin flaps of the posterior aspect of the thighs after total pelvic evisceration with removal of vulvo-perineal soft tissues in recurrent vulvar squamous carcinoma].","authors":"M Rinaldi,&nbsp;G Cormio,&nbsp;V Bucaria,&nbsp;P Di Tonno,&nbsp;F Marino,&nbsp;D F Altomare","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report of a case of a fortythree years old women affected by squamous cell cancer of the vulva (T3N0M0). Despite curative treatment (radical vulvectomy with bilateral inguinal and femoral lymphadenectomy), after 41 months she had a local recurrence, retreated with surgery and radiotherapy; another recurrence, after 29 months was treated with chemotherapy, without results. Because of local diffusion with infiltration of the urethra and anus, the patient was submitted to demolitive operation (total pelvic evisceratio, excision of pelvic and perineal soft tissues and reconstruction with rotating skin flaps of the posterior face of the thighs). After two years of follow up, the patient is alive without evidence of disease.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S208"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25822392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Feasibility and reliability of the study of sentinel lymph nodes with immunohistochemical technique in colonic carcinoma].","authors":"G Pasquini,&nbsp;V Bruni,&nbsp;P M Amodio,&nbsp;P Bonatti,&nbsp;L Martinengo,&nbsp;G Santi,&nbsp;P Mazzarella,&nbsp;M Piciollo,&nbsp;E Bigonzoni,&nbsp;A Goglia,&nbsp;F Rubino,&nbsp;E Piccioni,&nbsp;B Battisti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sentinel lymph node sampling, in patients with resectable colon cancer, improved identification of lymph node disease and identified patients likely to benefit from adjuvant therapy. This study examined whether sentinel node sampling accurately predicted lymph node status for patients with resectable colon cancer.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S28"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25821050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Decisional algorithm in extended neoplasms of the hypopharynx and the cervical esophagus].","authors":"M Benazzo,&nbsp;G Bertino,&nbsp;R Spasiano,&nbsp;P Gatti,&nbsp;M Capelli","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hypopharynx reconstruction must deal with restoration of not a simple tubed conduit but a complex arrangement of constrictive and propulsive forces with fine sensory circuits. The chosen surgical approach should guarantee both complete removal of tumor and re-establishement of the two primary functions of the district: first swallowing and then phonation. We retrospectively reviewed data of 67 patients who had undergone oncologic reconstruction of hypopharynx with either pedicled or free flaps at the ENT Department of IRCCS Policlinico S Matteo, University of Pavia, between November 1994 and July 2004. Type and extension of the defect following cancer removal guided the selection of reconstructive procedure. Partial defects, with more than 50% mucosa spared, in absence of chance of being closed primarly, were covered with radial forearm free flaps as first choice; pedicled flaps such as pectoralis major and SCM rotational flaps were used instead if free flaps contraindicated by general and/or local conditions. With circumferential defects reconstruction was accomplished by means of jejunum free flap, as first choice. Adverse local abdominal conditions mandated the alternative use of either tubulized or tunnelized fasciocutaneous free flaps, such as radial forearm and lateral thigh. When free flaps use contraindicated, or in case of salvage surgery after flap loss, pectoralis major and latissimus dorsi pedicled flap were chosen. Both reconstructions with free and pedicled flaps were successful in an high percentage of cases (>85%). Analysis of incidence and causes of flap failure are reported in this work. In the free flaps group of patients a lower rate of complications were registered, allowing a faster patient discharge from hospital (36% versus 81.3%). An oral swallowing function was gained in 92% of free flaps and 62.5% of pedicled flaps. Excellent and exclusive oral nutrition (free diet), was obtained in 54% of free flaps and 25% of pedicled flaps. None of patients undergone laryngectomy coupled in both groups with pharyngectomy achieved an intelligible esophageal speech. Only patients in the free flaps group benefitted from voice prosthesis implant: in fact this procedure was avoided in pedicled flaps due to the excessive tissue bulk. In conclusion, the data collected suggest that free flaps rapresent the first choice for both partial and total oncologic hypopharyngeal reconstruction, while pedicled flaps should be taken into account when free ones contraindicated by general or vascular conditions.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S190-2"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25821249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Conservative treatment of breast carcinoma in small breasts: new minimally invasive surgical technique].","authors":"S Sorrentino,&nbsp;S Scappin,&nbsp;F Coppa,&nbsp;P Citta,&nbsp;G M Caria","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To achieve satisfactory cosmetic results after breast conserving treatment (BCT) of cancer in patients (with small breasts, the association of BCT and bilateral video-assisted augmentation mammoplasty with differentiated prosthesis volume was performed. From January 2001 21 small breast pts with breast cancer (stage T1N0M0) were treated with BCT and immediate trans-axillary video-assisted breast reconstruction with differentiated volumes. In 15 patients sentinel node biopsy was performed and 6 patients required total axillary dissection. Tumor-free margins were confirmed by histological examination. All patients underwent postoperative radiotherapy. Cosmetic results were evaluated through 6 parameters: breast shape with and without underwear, symmetry, mobility, inframammary fold, tenderness. We observed 4 minor complications: seroma3, paresthesia and slight arm weakness. Mini-invasive surgical revision was required in 3 cases due to scar retraction of the prosthesis pocket. Prosthesis volume resulted 30% (range, 0-47%) higher in the affected side. Cosmetic result was positive in 85% of cases (excellent 15%, good 45%, fair 25%). Trans-axillary video-assisted breast mammoplasty with differentiated prosthesis volumes allows to obtain good aesthetic results in small breast patients and to extend BCT indications with a low morbidity rate.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S178-9"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25821387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}