I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]最新文献

{"title":"[Laparoscopic intraperitoneal antiblastic hyperthermic chemoperfusion in the treatment of refractory neoplastic ascites. Preliminary results].","authors":"M Valle,&nbsp;A Garofalo,&nbsp;O Federici,&nbsp;F Cavaliere","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A method of laparoscopic continuous hyperthermic peritoneal perfusion (CHPP) is proposed for the treatment of debilitating malignant ascites. The authors report 14 cases of peritoneal malignancy, not amenable to peritonectomy due to massive infiltration of the small bowel. The ascites disappeared in all treated cases.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S122-3"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25820960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Feasibility and reliability of the study of sentinel lymph nodes with immunohistochemical technique in colonic carcinoma].","authors":"G Pasquini,&nbsp;V Bruni,&nbsp;P M Amodio,&nbsp;P Bonatti,&nbsp;L Martinengo,&nbsp;G Santi,&nbsp;P Mazzarella,&nbsp;M Piciollo,&nbsp;E Bigonzoni,&nbsp;A Goglia,&nbsp;F Rubino,&nbsp;E Piccioni,&nbsp;B Battisti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sentinel lymph node sampling, in patients with resectable colon cancer, improved identification of lymph node disease and identified patients likely to benefit from adjuvant therapy. This study examined whether sentinel node sampling accurately predicted lymph node status for patients with resectable colon cancer.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S28"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25821050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Segmental resection of the third and fourth portions of the duodenum after intestinal derotation for a GIST: a case report.","authors":"P De Nicola,&nbsp;N Di Bartolomeo,&nbsp;F Francomano,&nbsp;A D'Aulerio,&nbsp;P Innocenti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We describe a case in which segmental resection of the third and fourth portion of the duodenum was performed for a very rare duodenal gastrointestinal tumor (GIST). A 58-year old man presented with melena. Capsule endoscopy revealed a pathological bleeding of the duodenum and oral contrast-CT enema confirmed a lesion of the duodenum inferior knee, measuring 3.5 cm in diameter. Such an image suggested a duodenal leiomyoma. Segmental resection of the third and fourth portion of the duodenum after intestinal derotation (Valdoni-Strong's procedure) was carried out and there were no post-operative complications. Pancreas sparing duodenal resection is at the present time indicated only in selected cases. The duodenal resection associated with bowel and right colon derotation has proved to be a safe and adequate procedure and could be preferred to other procedures.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S108-10"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25821063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Decisional algorithm in extended neoplasms of the hypopharynx and the cervical esophagus].","authors":"M Benazzo,&nbsp;G Bertino,&nbsp;R Spasiano,&nbsp;P Gatti,&nbsp;M Capelli","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hypopharynx reconstruction must deal with restoration of not a simple tubed conduit but a complex arrangement of constrictive and propulsive forces with fine sensory circuits. The chosen surgical approach should guarantee both complete removal of tumor and re-establishement of the two primary functions of the district: first swallowing and then phonation. We retrospectively reviewed data of 67 patients who had undergone oncologic reconstruction of hypopharynx with either pedicled or free flaps at the ENT Department of IRCCS Policlinico S Matteo, University of Pavia, between November 1994 and July 2004. Type and extension of the defect following cancer removal guided the selection of reconstructive procedure. Partial defects, with more than 50% mucosa spared, in absence of chance of being closed primarly, were covered with radial forearm free flaps as first choice; pedicled flaps such as pectoralis major and SCM rotational flaps were used instead if free flaps contraindicated by general and/or local conditions. With circumferential defects reconstruction was accomplished by means of jejunum free flap, as first choice. Adverse local abdominal conditions mandated the alternative use of either tubulized or tunnelized fasciocutaneous free flaps, such as radial forearm and lateral thigh. When free flaps use contraindicated, or in case of salvage surgery after flap loss, pectoralis major and latissimus dorsi pedicled flap were chosen. Both reconstructions with free and pedicled flaps were successful in an high percentage of cases (>85%). Analysis of incidence and causes of flap failure are reported in this work. In the free flaps group of patients a lower rate of complications were registered, allowing a faster patient discharge from hospital (36% versus 81.3%). An oral swallowing function was gained in 92% of free flaps and 62.5% of pedicled flaps. Excellent and exclusive oral nutrition (free diet), was obtained in 54% of free flaps and 25% of pedicled flaps. None of patients undergone laryngectomy coupled in both groups with pharyngectomy achieved an intelligible esophageal speech. Only patients in the free flaps group benefitted from voice prosthesis implant: in fact this procedure was avoided in pedicled flaps due to the excessive tissue bulk. In conclusion, the data collected suggest that free flaps rapresent the first choice for both partial and total oncologic hypopharyngeal reconstruction, while pedicled flaps should be taken into account when free ones contraindicated by general or vascular conditions.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S190-2"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25821249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Conservative treatment of breast carcinoma in small breasts: new minimally invasive surgical technique].","authors":"S Sorrentino,&nbsp;S Scappin,&nbsp;F Coppa,&nbsp;P Citta,&nbsp;G M Caria","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To achieve satisfactory cosmetic results after breast conserving treatment (BCT) of cancer in patients (with small breasts, the association of BCT and bilateral video-assisted augmentation mammoplasty with differentiated prosthesis volume was performed. From January 2001 21 small breast pts with breast cancer (stage T1N0M0) were treated with BCT and immediate trans-axillary video-assisted breast reconstruction with differentiated volumes. In 15 patients sentinel node biopsy was performed and 6 patients required total axillary dissection. Tumor-free margins were confirmed by histological examination. All patients underwent postoperative radiotherapy. Cosmetic results were evaluated through 6 parameters: breast shape with and without underwear, symmetry, mobility, inframammary fold, tenderness. We observed 4 minor complications: seroma3, paresthesia and slight arm weakness. Mini-invasive surgical revision was required in 3 cases due to scar retraction of the prosthesis pocket. Prosthesis volume resulted 30% (range, 0-47%) higher in the affected side. Cosmetic result was positive in 85% of cases (excellent 15%, good 45%, fair 25%). Trans-axillary video-assisted breast mammoplasty with differentiated prosthesis volumes allows to obtain good aesthetic results in small breast patients and to extend BCT indications with a low morbidity rate.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S178-9"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25821387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Duodenocephalopancreatectomy with pylorus sparing and occlusion of the main bile duct with fibrin glue].","authors":"I M Civello,&nbsp;C Nigro,&nbsp;D Matera,&nbsp;F Brandara,&nbsp;F Greco,&nbsp;G Brisinda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The leakage of pancreaticojejunostomy represents the main technical post-operative complication after pancreaticoduodenectomy. Because pancreatic fistula can be the source of morbidity and mortality and it is related to the integrity of the pancreatic-enteric anastomosis, a number of technical modification have been suggested, including pancreaticojejunostomy, pancreaticogastrostomy and occlusion of the main pancreatic duct with fibrin glue. The incidence of leakage is particularly high in case of narrow ducts and tender pancreatic glands; in such conditions some experiences in literature suggest the technique of occlusion of the main pancreatic duct with fibrin glue.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S63"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25822102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Results of emergency surgery in patients with Moschowitz's disease refractory to hematological treatment: is splenectomy always advisable?","authors":"R Caronna,&nbsp;M Cardi,&nbsp;G Meloni,&nbsp;S Mangioni,&nbsp;G Spera,&nbsp;M Benedetti,&nbsp;V Frantellizzi,&nbsp;D Layek,&nbsp;S Catinelli,&nbsp;M Schiratti,&nbsp;P Chirletti","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Patients with thrombotic thrombocytopenic purpura (TTP), Moschowitz's disease, run a high risk of perioperative bleeding and need intensive hematologic support. In some patients, TTP is associated with cancer but the surgical role in these patients is still unclear. To illustrate the surgical problems and outcome we present the case histories of three patients with TTP observed in our emergency department.</p><p><strong>Materials and methods: </strong>Two patients had TTP secondary to cancer and one patient with primary TTP (no evidence of neoplasia) had emergency operation for gastric hemorrhage, occlusion and TTP unresponsive to plasmapheresis.</p><p><strong>Results: </strong>The first two patients who had not radical resection of cancer and no splenectomy, died for TTP complications. The third patient who underwent emergency splenectomy, had an uneventful postoperative course and TTP completely regressed.</p><p><strong>Conclusions: </strong>These case reports suggest that patients with TTP should be screened to rule out cancer. In patients with acute cancer-related complications emergency surgery should aim to resect the cancer. An associated splenectomy may increase the effectiveness of postoperative hematologic therapy.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S146-7"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25822111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are the preoperative histological findings accurate for the choice of the surgical approach in ulcerative colitis associated with colorectal cancer/dysplasia?","authors":"A Garcea,&nbsp;M Fazi,&nbsp;F Ficari,&nbsp;R Valanzano,&nbsp;F Tonelli","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S3"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25822378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Association of mutations of K-RAS oncogene and deletions of 18Q with lymph node metastasis of colorectal cancer].","authors":"A Leone,&nbsp;R Pisa,&nbsp;R Gasbarra,&nbsp;P Graziano,&nbsp;D Remotti,&nbsp;M Valle,&nbsp;A Garofalo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Molecular characterization of gastrointestinal cancer has greatly helped the definition of the key steps of the malignant transformation process and made it the best understood among the malignant cancers. Genetic influences on prognosis may have important implications for the management of the disease and help to design patient-tailored therapy. In order to acquire additional knowledge on this issue we have commenced an institutional study with the aim to identify the most frequent molecular alterations and make a correlation with the conventional histopathological parameters.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S207"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25822383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Pheochromocytoma: role of preoperative diagnosis in the assessment of malignancy risk and in the choice of surgical approach].","authors":"C P Lombardi,&nbsp;M Raffaelli,&nbsp;C De Crea,&nbsp;E Traini,&nbsp;A M D'Amore,&nbsp;R Bellantone","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Pheochromocytomas are malignant in 5-26% of the cases. Differential diagnosis with benign lesions can be difficult even on a pathological basis. Local invasion and distant metastasis are the only well established indicators of malignancy. It has been reported that the risk of malignancy increases with the lesion size. Despite safe laparoscopic adrenalectomy (LA) has been reported for lesions up to 10 cm, it is considered hazardous for pheochromocytoma larger than 6 cm, because of the risk of malignancy and iatrogenic pheochromocytomatosis. We evaluated the possibility to pre-operatively recognize pheochromocytomas at risk of being malignant that should not be selected for LA. The medical records of all the patients who underwent adrenalectomy for pheochromocytoma were reviewed. All the preoperatively available data (demographic, clinical, biochemical and radiological) were recorded as well as final pathological diagnosis. Comparative analysis of patients with benign and malignant pheochromocytomas was performed. Sixty-three adrenalectomies for pheochromocytoma were performed in 60 patients. Fifty-seven benign and 6 malignant pheochromocytomas were identified. No significant difference was found between patients with malignant and benign lesions concerning age, gender, family history, symptoms, laboratory and radiological findings. In particular, no significant difference was found for lesion size between the benign (63.3 +/- 30.6 mm, range, 20-150) and the malignant group (48.6 +/- 16.5 mm; range, 30-70). The largest diameter recorded for a malignant lesion was 70 mm. No preoperatively available data can reliably differentiate between benign and malignant pheochromocytomas. All malignant lesions in this series were smaller than 7 cm. Thus, pheochromocytoma size does not seem a reliable predictor of malignancy. In absence of the evidence of gross local invasion or metastatic disease, LA can be safely proposed also for large lesions. Conversion is mandatory in presence of local invasion or difficult dissection that could involve inadequate resection.</p>","PeriodicalId":84869,"journal":{"name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","volume":"4 3","pages":"S211"},"PeriodicalIF":0.0,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25822387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}