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Arrhythmias and Conduction Disturbances in Autoimmune Rheumatic Disorders. 自身免疫性风湿病的心律失常和传导障碍。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2021-04-01 DOI: 10.15420/aer.2020.43
Sotiris C Plastiras, Haralampos M Moutsopoulos
{"title":"Arrhythmias and Conduction Disturbances in Autoimmune Rheumatic Disorders.","authors":"Sotiris C Plastiras,&nbsp;Haralampos M Moutsopoulos","doi":"10.15420/aer.2020.43","DOIUrl":"https://doi.org/10.15420/aer.2020.43","url":null,"abstract":"<p><p>Rhythm and conduction disturbances and sudden cardiac death are important manifestations of cardiac involvement in autoimmune rheumatic diseases (ARD), which have a serious impact on morbidity and mortality. While the underlying arrhythmogenic mechanisms are multifactorial, myocardial fibrosis plays a pivotal role. It accounts for a substantial portion of cardiac mortality and may manifest as atrial and ventricular arrhythmias, conduction system abnormalities, biventricular cardiac failure or sudden death. In patients with ARD, myocardial fibrosis is considered to be the hallmark of cardiac involvement as a result of inflammatory process or to coronary artery occlusive disease. Myocardial fibrosis constitutes the pathological substrates for reentrant circuits. The presence of supraventricular extra systoles, tachyarrhythmias, ventricular activity and conduction disturbances are not uncommon in patients with ARDs, more often in systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis, inflammatory muscle disorders and anti-neutrophil cytoplasm antibody-associated vasculitis. In this review, the type, the relative prevalence and the underlying mechanisms of rhythm and conduction disturbances in the emerging field of cardiorheumatology are provided.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"10 1","pages":"17-25"},"PeriodicalIF":3.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/01/66/aer-10-17.PMC8076972.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38860838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Leadless Left Ventricular Endocardial Pacing and Left Bundle Branch Area Pacing for Cardiac Resynchronisation Therapy. 用于心脏再同步化疗法的无引线左心室心内膜起搏和左束支区起搏。
IF 2.6
Arrhythmia & Electrophysiology Review Pub Date : 2021-04-01 DOI: 10.15420/aer.2020.46
Baldeep S Sidhu, Justin Gould, Mark K Elliott, Vishal Mehta, Steven Niederer, Christopher A Rinaldi
{"title":"Leadless Left Ventricular Endocardial Pacing and Left Bundle Branch Area Pacing for Cardiac Resynchronisation Therapy.","authors":"Baldeep S Sidhu, Justin Gould, Mark K Elliott, Vishal Mehta, Steven Niederer, Christopher A Rinaldi","doi":"10.15420/aer.2020.46","DOIUrl":"10.15420/aer.2020.46","url":null,"abstract":"<p><p>Cardiac resynchronisation therapy is an important intervention to reduce mortality and morbidity, but even in carefully selected patients approximately 30% fail to improve. This has led to alternative pacing approaches to improve patient outcomes. Left ventricular (LV) endocardial pacing allows pacing at site-specific locations that enable the operator to avoid myocardial scar and target areas of latest activation. Left bundle branch area pacing (LBBAP) provides a more physiological activation pattern and may allow effective cardiac resynchronisation. This article discusses LV endocardial pacing in detail, including the indications, techniques and outcomes. It discusses LBBAP, its potential benefits over His bundle pacing and procedural outcomes. Finally, it concludes with the future role of endocardial pacing and LBBAP in heart failure patients.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"10 1","pages":"45-50"},"PeriodicalIF":2.6,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ed/83/aer-10-45.PMC8076968.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38873928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anisotropic Cardiac Conduction. 各向异性心脏传导
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2020-12-01 DOI: 10.15420/aer.2020.04
Irum Kotadia, John Whitaker, Caroline Roney, Steven Niederer, Mark O'Neill, Martin Bishop, Matthew Wright
{"title":"Anisotropic Cardiac Conduction.","authors":"Irum Kotadia, John Whitaker, Caroline Roney, Steven Niederer, Mark O'Neill, Martin Bishop, Matthew Wright","doi":"10.15420/aer.2020.04","DOIUrl":"10.15420/aer.2020.04","url":null,"abstract":"<p><p>Anisotropy is the property of directional dependence. In cardiac tissue, conduction velocity is anisotropic and its orientation is determined by myocyte direction. Cell shape and size, excitability, myocardial fibrosis, gap junction distribution and function are all considered to contribute to anisotropic conduction. In disease states, anisotropic conduction may be enhanced, and is implicated, in the genesis of pathological arrhythmias. The principal mechanism responsible for enhanced anisotropy in disease remains uncertain. Possible contributors include changes in cellular excitability, changes in gap junction distribution or function and cellular uncoupling through interstitial fibrosis. It has recently been demonstrated that myocyte orientation may be identified using diffusion tensor magnetic resonance imaging in explanted hearts, and multisite pacing protocols have been proposed to estimate myocyte orientation and anisotropic conduction in vivo. These tools have the potential to contribute to the understanding of the role of myocyte disarray and anisotropic conduction in arrhythmic states.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"9 4","pages":"202-210"},"PeriodicalIF":3.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8c/aa/aer-09-202.PMC7788398.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9105604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Big Data and Artificial Intelligence: Opportunities and Threats in Electrophysiology. 大数据和人工智能：电生理学的机遇与威胁。
IF 2.6
Arrhythmia & Electrophysiology Review Pub Date : 2020-11-01 DOI: 10.15420/aer.2020.26
Rutger R van de Leur, Machteld J Boonstra, Ayoub Bagheri, Rob W Roudijk, Arjan Sammani, Karim Taha, Pieter Afm Doevendans, Pim van der Harst, Peter M van Dam, Rutger J Hassink, René van Es, Folkert W Asselbergs
{"title":"Big Data and Artificial Intelligence: Opportunities and Threats in Electrophysiology.","authors":"Rutger R van de Leur, Machteld J Boonstra, Ayoub Bagheri, Rob W Roudijk, Arjan Sammani, Karim Taha, Pieter Afm Doevendans, Pim van der Harst, Peter M van Dam, Rutger J Hassink, René van Es, Folkert W Asselbergs","doi":"10.15420/aer.2020.26","DOIUrl":"10.15420/aer.2020.26","url":null,"abstract":"<p><p>The combination of big data and artificial intelligence (AI) is having an increasing impact on the field of electrophysiology. Algorithms are created to improve the automated diagnosis of clinical ECGs or ambulatory rhythm devices. Furthermore, the use of AI during invasive electrophysiological studies or combining several diagnostic modalities into AI algorithms to aid diagnostics are being investigated. However, the clinical performance and applicability of created algorithms are yet unknown. In this narrative review, opportunities and threats of AI in the field of electrophysiology are described, mainly focusing on ECGs. Current opportunities are discussed with their potential clinical benefits as well as the challenges. Challenges in data acquisition, model performance, (external) validity, clinical implementation, algorithm interpretation as well as the ethical aspects of AI research are discussed. This article aims to guide clinicians in the evaluation of new AI applications for electrophysiology before their clinical implementation.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"9 3","pages":"146-154"},"PeriodicalIF":2.6,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5d/d8/aer-09-146.PMC7675143.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38644925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differential Diagnosis of Wide QRS Tachycardias. 宽QRS心动过速的鉴别诊断。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2020-11-01 DOI: 10.15420/aer.2020.20
Demosthenes G Katritsis, Josep Brugada
{"title":"Differential Diagnosis of Wide QRS Tachycardias.","authors":"Demosthenes G Katritsis,&nbsp;Josep Brugada","doi":"10.15420/aer.2020.20","DOIUrl":"https://doi.org/10.15420/aer.2020.20","url":null,"abstract":"<p><p>In this article, the authors discuss the differential diagnostic methods used in clinical practice to identify types of wide QRS tachycardias (QRS duration >120 ms). A correct diagnosis is critical to management, as misdiagnosis and the administration of drugs usually utilised for supraventricular tachycardia can be harmful for patients with ventricular tachycardia.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"9 3","pages":"155-160"},"PeriodicalIF":3.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b1/f8/aer-09-155.PMC7675136.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38644926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Rhythm Control in Heart Failure Patients with Atrial Fibrillation. 心衰合并心房颤动患者的心律控制。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2020-11-01 DOI: 10.15420/aer.2020.23
William Eysenck, Magdi Saba
{"title":"Rhythm Control in Heart Failure Patients with Atrial Fibrillation.","authors":"William Eysenck,&nbsp;Magdi Saba","doi":"10.15420/aer.2020.23","DOIUrl":"https://doi.org/10.15420/aer.2020.23","url":null,"abstract":"<p><p>AF and heart failure (HF) commonly coexist. Left atrial ablation is an effective treatment to maintain sinus rhythm (SR) in patients with AF. Recent evidence suggests that the use of ablation for AF in patients with HF is associated with an improved left ventricular ejection fraction and lower death and HF hospitalisation rates. We performed a systematic search of world literature to analyse the association in more detail and to assess the utility of AF ablation as a non-pharmacological tool in the treatment of patients with concomitant HF.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"9 3","pages":"161-166"},"PeriodicalIF":3.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4c/81/aer-09-161.PMC7675141.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38644927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
A New Era in Zero X-ray Ablation. 零 X 射线烧蚀的新纪元。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2020-11-01 DOI: 10.15420/aer.2020.02
Giuseppe Mascia, Marzia Giaccardi
{"title":"A New Era in Zero X-ray Ablation.","authors":"Giuseppe Mascia, Marzia Giaccardi","doi":"10.15420/aer.2020.02","DOIUrl":"10.15420/aer.2020.02","url":null,"abstract":"<p><p>In this article, the authors focus on the importance of the zero X-ray ablation approach in electrophysiology. Radiation exposure related to conventional transcatheter ablation carries small but non-negligible stochastic and deterministic effects on health. Non-fluoroscopic mapping systems can significantly reduce, or even completely avoid, radiological exposure. The zero X-ray approach determines potential clinical benefits in terms of reduction of ionising radiation exposure, as well as safe technical advantages. The use of this method can result in similar outcomes when compared to the conventional fluoroscopic technique. These results are achieved without altering the duration, or compromising the effectiveness and safety, of the procedure. The zero X-ray ablation approach is a feasible and safe alternative to fluoroscopy, which is often only used in selected cases for troubleshooting. The non-fluoroscopic approach is considered a milestone for cancer prevention in ablation procedures.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"9 3","pages":"121-127"},"PeriodicalIF":3.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d4/4d/aer-09-121.PMC7675142.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38644509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrophysiology in the Era of Coronavirus Disease 2019. 2019冠状病毒病时代的电生理学
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2020-11-01 DOI: 10.15420/aer.2020.32
Vijayabharathy Kanthasamy, Richard J Schilling
{"title":"Electrophysiology in the Era of Coronavirus Disease 2019.","authors":"Vijayabharathy Kanthasamy,&nbsp;Richard J Schilling","doi":"10.15420/aer.2020.32","DOIUrl":"https://doi.org/10.15420/aer.2020.32","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) is caused by the novel betacoronavirus officially named by the WHO as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has spread rapidly globally since the first case reported in Wuhan, China in December 2019 and has now affected more than 12 million people worldwide, with varying fatality rates across different countries. The clinical presentation of COVID-19 is heterogeneous and varies from asymptomatic to severe pneumonia/acute respiratory distress syndrome (ARDS) requiring invasive mechanical ventilation. In addition, a hyperinflammatory state secondary to cytokine release syndrome leads to hypercoagulation, multiorgan failure and increased mortality.","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"9 3","pages":"167-170"},"PeriodicalIF":3.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5e/f6/aer-09-167.PMC7675140.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38644928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Impact of Micro-, Mini- and Multi-Electrode Mapping on Ventricular Substrate Characterisation. 微型、小型和多电极绘图对心室基底特征描述的影响
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2020-11-01 DOI: 10.15420/aer.2020.24
Benjamin Berte, Katja Zeppenfeld, Roderick Tung
{"title":"Impact of Micro-, Mini- and Multi-Electrode Mapping on Ventricular Substrate Characterisation.","authors":"Benjamin Berte, Katja Zeppenfeld, Roderick Tung","doi":"10.15420/aer.2020.24","DOIUrl":"10.15420/aer.2020.24","url":null,"abstract":"<p><p>Accurate substrate characterisation may improve the evolving understanding and treatment of cardiac arrhythmias. During substrate-based ablation techniques, wide practice variations exist with mapping via dedicated multi-electrode catheter or conventional ablation catheters. Recently, newer ablation catheter technology with embedded mapping electrodes have been introduced. This article focuses on the general misconceptions of voltage mapping and more specific differences in unipolar and bipolar signal morphology, field of view, signal-to-noise ratio, mapping capabilities (density and resolution), catheter-specific voltage thresholds and impact of micro-, mini- and multi-electrodes for substrate mapping. Efficiency and cost-effectiveness of different catheter types are discussed. Increasing sampling density with smaller electrodes allows for higher resolution with a greater likelihood to record near-field electrical information. These advances may help to further improve our mechanistic understanding of the correlation between substrate and ventricular tachycardia, as well as macro-reentry arrhythmia in humans.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"9 3","pages":"128-135"},"PeriodicalIF":3.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6a/62/aer-09-128.PMC7675146.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38644511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atrial Fibrillation Structural Substrates: Aetiology, Identification and Implications. 心房颤动的结构基质:病因学、鉴定和意义。
IF 3
Arrhythmia & Electrophysiology Review Pub Date : 2020-11-01 DOI: 10.15420/aer.2020.19
Ahmed M Al-Kaisey, Ramanathan Parameswaran, Jonathan M Kalman
{"title":"Atrial Fibrillation Structural Substrates: Aetiology, Identification and Implications.","authors":"Ahmed M Al-Kaisey,&nbsp;Ramanathan Parameswaran,&nbsp;Jonathan M Kalman","doi":"10.15420/aer.2020.19","DOIUrl":"https://doi.org/10.15420/aer.2020.19","url":null,"abstract":"<p><p>Atrial remodelling in AF underlines the electrical, structural and mechanical changes in the atria of patients with AF. Several risk factors for AF contribute to the development of the atrial substrate, with some evidence that atrial remodelling reversal is possible with targeted intervention. In this article, the authors review the electrophysiological changes that characterise the atrial substrate in patients with AF risk factors. They also discuss the pitfalls of mapping the atrial substrate and the implications for developing tailored ablation strategies to improve outcomes in patients with AF.</p>","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"9 3","pages":"113-120"},"PeriodicalIF":3.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/83/e8/aer-09-113.PMC7675137.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38644510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
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