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PAF-acether-PGE2 interactions in guinea-pig tracheal preparations paf -醚- pge2在豚鼠气管制剂中的相互作用
Research in prostaglandins Pub Date : 1988-05-01 DOI: 10.1016/0090-6980(88)90262-6
S. Brunelleschi, C. Brink, I. Haye-Legrand, R. Fantozzi, A. Giotti, C. Labat, F. Ledda, J. Benveniste
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引用次数: 0
Cationic lipid PAF antagonists. Examination of a strategy to improve oral activity 阳离子脂质PAF拮抗剂。考查提高口腔活动的策略
Research in prostaglandins Pub Date : 1988-05-01 DOI: 10.1016/0090-6980(88)90252-3
J. Tomesch, M. Prashad, J. Koletar, D. Handley, C. Winslow
{"title":"Cationic lipid PAF antagonists. Examination of a strategy to improve oral activity","authors":"J. Tomesch, M. Prashad, J. Koletar, D. Handley, C. Winslow","doi":"10.1016/0090-6980(88)90252-3","DOIUrl":"https://doi.org/10.1016/0090-6980(88)90252-3","url":null,"abstract":"","PeriodicalId":83897,"journal":{"name":"Research in prostaglandins","volume":"315 1","pages":"844"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80090065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
PAF-acether antagonists and LTC4 formation by human eosinophils paf -醚拮抗剂与人嗜酸性粒细胞形成LTC4
Research in prostaglandins Pub Date : 1988-05-01 DOI: 10.1016/0090-6980(88)90249-3
P. Bruijnzeel, P. Kok, M. Hamelink
{"title":"PAF-acether antagonists and LTC4 formation by human eosinophils","authors":"P. Bruijnzeel, P. Kok, M. Hamelink","doi":"10.1016/0090-6980(88)90249-3","DOIUrl":"https://doi.org/10.1016/0090-6980(88)90249-3","url":null,"abstract":"","PeriodicalId":83897,"journal":{"name":"Research in prostaglandins","volume":"7 1","pages":"843"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74355519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tetrahydrofuran derivatives as PAF-acether antagonists - structure-activity relationship 四氢呋喃衍生物作为paf -乙醚拮抗剂-构效关系
Research in prostaglandins Pub Date : 1988-05-01 DOI: 10.1016/0090-6980(88)90254-7
F. Heymans, C. Redeuilh, F. Massicot, B. Wichrowski, E. Favre, B. Spinewyn, N. Blavet, P. Braquet, J. Godfroid
{"title":"Tetrahydrofuran derivatives as PAF-acether antagonists - structure-activity relationship","authors":"F. Heymans, C. Redeuilh, F. Massicot, B. Wichrowski, E. Favre, B. Spinewyn, N. Blavet, P. Braquet, J. Godfroid","doi":"10.1016/0090-6980(88)90254-7","DOIUrl":"https://doi.org/10.1016/0090-6980(88)90254-7","url":null,"abstract":"","PeriodicalId":83897,"journal":{"name":"Research in prostaglandins","volume":"46 1","pages":"845"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77543217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
5-aryl-2 3-dihydroimidazo [2,1-a] isoquinolines. A novel class of platelet-activating factor (PAF) receptor antagonists structurally derived from the PAF molecule 5-芳基-2 - 3-二氢咪唑[2,1-a]异喹啉。一类新型血小板活化因子(PAF)受体拮抗剂在结构上来源于PAF分子
Research in prostaglandins Pub Date : 1988-05-01 DOI: 10.1016/0090-6980(88)90260-2
W. Houlihan, S. Cheon, D. Handley, D. Larson, V. Parrino, B. Reitter, G. Schmitt, C. Winslow
{"title":"5-aryl-2 3-dihydroimidazo [2,1-a] isoquinolines. A novel class of platelet-activating factor (PAF) receptor antagonists structurally derived from the PAF molecule","authors":"W. Houlihan, S. Cheon, D. Handley, D. Larson, V. Parrino, B. Reitter, G. Schmitt, C. Winslow","doi":"10.1016/0090-6980(88)90260-2","DOIUrl":"https://doi.org/10.1016/0090-6980(88)90260-2","url":null,"abstract":"","PeriodicalId":83897,"journal":{"name":"Research in prostaglandins","volume":"119 1","pages":"848"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77960919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Effect of three chinese herbal medicines(ligustrazine, chrysanthemum indicum, salviae miltiorrhizae) on PAF and ADP-induced platelet aggregation in vitro 川芎嗪、菊花、丹参三种中草药对体外PAF和adp诱导的血小板聚集的影响
Research in prostaglandins Pub Date : 1988-05-01 DOI: 10.1016/0090-6980(88)90247-X
J. V. Levy, Z-F Xie
{"title":"Effect of three chinese herbal medicines(ligustrazine, chrysanthemum indicum, salviae miltiorrhizae) on PAF and ADP-induced platelet aggregation in vitro","authors":"J. V. Levy, Z-F Xie","doi":"10.1016/0090-6980(88)90247-X","DOIUrl":"https://doi.org/10.1016/0090-6980(88)90247-X","url":null,"abstract":"","PeriodicalId":83897,"journal":{"name":"Research in prostaglandins","volume":"32 1","pages":"842"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87072226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Inhibitory action of WEB-2086 (a thieno-triazolodiazepine) and its cyclohexyl analog (WEB-2118) on platelet activating factor(PAF) induced aggregation of human platelets in whole blood WEB-2086(噻吩-三唑二氮卓类药物)及其环己基类似物WEB-2118对血小板活化因子(PAF)诱导的人血小板全血聚集的抑制作用
Research in prostaglandins Pub Date : 1988-05-01 DOI: 10.1016/0090-6980(88)90246-8
J. V. Levy, W. Chan
{"title":"Inhibitory action of WEB-2086 (a thieno-triazolodiazepine) and its cyclohexyl analog (WEB-2118) on platelet activating factor(PAF) induced aggregation of human platelets in whole blood","authors":"J. V. Levy, W. Chan","doi":"10.1016/0090-6980(88)90246-8","DOIUrl":"https://doi.org/10.1016/0090-6980(88)90246-8","url":null,"abstract":"","PeriodicalId":83897,"journal":{"name":"Research in prostaglandins","volume":"46 1","pages":"841"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80707766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Synthesis and structure-activity relationship of 2,5-diaryltetrahydrofurans as PAF antagonists PAF拮抗剂2,5-二芳基四氢呋喃的合成及构效关系
Research in prostaglandins Pub Date : 1988-05-01 DOI: 10.1016/0090-6980(88)90255-9
T. Biftu, J. C. Chabala, J. Acton, T. Beattie, D. Brooker, R. Bugianesi, M. N. Chang, P. Chiang, N. Gable, N. Girotra, D. Graham, C. Kuo, M. Ponpipom, S. Sahoo, T. Shen, K. Thompson, S. S. Yang, S.-B. Hwang, T. Doebber
{"title":"Synthesis and structure-activity relationship of 2,5-diaryltetrahydrofurans as PAF antagonists","authors":"T. Biftu, J. C. Chabala, J. Acton, T. Beattie, D. Brooker, R. Bugianesi, M. N. Chang, P. Chiang, N. Gable, N. Girotra, D. Graham, C. Kuo, M. Ponpipom, S. Sahoo, T. Shen, K. Thompson, S. S. Yang, S.-B. Hwang, T. Doebber","doi":"10.1016/0090-6980(88)90255-9","DOIUrl":"https://doi.org/10.1016/0090-6980(88)90255-9","url":null,"abstract":"","PeriodicalId":83897,"journal":{"name":"Research in prostaglandins","volume":"42 1","pages":"846"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80851891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Tolerance study, pharmacokinetics and ex vivo PAF-induced platelet aggregation after repeated oral doses of 48740 RP in normal volunteers 正常志愿者重复口服48740 RP后的耐受性研究、药代动力学和体外paf诱导的血小板聚集
Research in prostaglandins Pub Date : 1988-05-01 DOI: 10.1016/0090-6980(88)90238-9
J. Pinquier, P. Sedivy, R. Bruno, F. Gaisne, A. Opriou, F. Bompart, Lauture D. de, G. Strauch, J. Gregoire
{"title":"Tolerance study, pharmacokinetics and ex vivo PAF-induced platelet aggregation after repeated oral doses of 48740 RP in normal volunteers","authors":"J. Pinquier, P. Sedivy, R. Bruno, F. Gaisne, A. Opriou, F. Bompart, Lauture D. de, G. Strauch, J. Gregoire","doi":"10.1016/0090-6980(88)90238-9","DOIUrl":"https://doi.org/10.1016/0090-6980(88)90238-9","url":null,"abstract":"","PeriodicalId":83897,"journal":{"name":"Research in prostaglandins","volume":"12 1","pages":"837"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90638928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
PAF antagonists SDZ 63–441 and SDZ 63–675. Synthesis of and pharmacological characterization of the individual enantiomers PAF拮抗剂SDZ 63-441和SDZ 63-675。单个对映体的合成和药理学表征
Research in prostaglandins Pub Date : 1988-05-01 DOI: 10.1016/0090-6980(88)90253-5
J. Tomesch, J. Koletar, M. Prashad, D. Handley, D. Larson, C. Winslow
{"title":"PAF antagonists SDZ 63–441 and SDZ 63–675. Synthesis of and pharmacological characterization of the individual enantiomers","authors":"J. Tomesch, J. Koletar, M. Prashad, D. Handley, D. Larson, C. Winslow","doi":"10.1016/0090-6980(88)90253-5","DOIUrl":"https://doi.org/10.1016/0090-6980(88)90253-5","url":null,"abstract":"","PeriodicalId":83897,"journal":{"name":"Research in prostaglandins","volume":"34 1","pages":"845"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76718535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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