{"title":"Pharmacotherapy of diabetes mellitus: implications for the prevention and treatment of cardiovascular disease.","authors":"Enzo Ragucci, Joel Zonszein, William H Frishman","doi":"10.1097/01.HDX.0000050411.62103.F5","DOIUrl":"https://doi.org/10.1097/01.HDX.0000050411.62103.F5","url":null,"abstract":"<p><p>Diabetes mellitus in adults is associated with an increased risk of premature vascular disease and a higher mortality rate. The presence of other risk factors, often seen in diabetic patients, such as systemic hypertension, augments the rate of vascular diseases. Evidence is growing that tight control of hyperglycemia using insulin and/or oral hypoglycemic agents will modify this risk. More aggressive control of concomitant hypertension and/or hyperlipidemia is also required. Diabetic patients who have myocardial infarctions do worse than nondiabetic patients. Various strategies to improve outcomes include the use of tight blood glucose control, and various coronary interventions are currently under clinical study.</p>","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"5 1","pages":"18-33"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.HDX.0000050411.62103.F5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22215691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bulent Atac, Driola Brahaj, William H Frishman, Robert Lerner
{"title":"Anemia and hypocholesterolemia.","authors":"Bulent Atac, Driola Brahaj, William H Frishman, Robert Lerner","doi":"10.1097/01.HDX.0000050420.79522.09","DOIUrl":"https://doi.org/10.1097/01.HDX.0000050420.79522.09","url":null,"abstract":"<p><p>The authors reviewed the available data on the relationship between hypocholesterolemia and anemia with various etiologies. The data were collected from sources identified by a MEDLINE search of English-language literature published between 1966 and 2001 and bibliographies of relevant articles. The study selection included primary research articles, metaanalyses, and abstracts concerning the relation between hypocholesterolemia and anemia. Textbooks, meeting proceedings, and reference lists were also searched. Despite differences in study design, a relation was found between hematocrit and serum cholesterol levels and between hemoglobin and cholesterol levels. Further studies are required to determine the exact etiology and clinical significance of these findings.</p>","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"5 1","pages":"65-71"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.HDX.0000050420.79522.09","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22215695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Should salt restriction be advised for every patient with hypertension?","authors":"Krishan L Gupta, Veena Gupta","doi":"10.1097/00132580-200211000-00010","DOIUrl":"https://doi.org/10.1097/00132580-200211000-00010","url":null,"abstract":"","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"4 6","pages":"397-8"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/00132580-200211000-00010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22120458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pericardial disease in the oncology patient.","authors":"Avi S Retter","doi":"10.1097/00132580-200211000-00008","DOIUrl":"https://doi.org/10.1097/00132580-200211000-00008","url":null,"abstract":"<p><p>Malignant pericardial disease is a serious and common problem seen in patients with cancer. It is usually due to metastatic spread of the underlying malignancy or a complication of radiation therapy. The patient may have a mild, subtle presentation, as is often seen in the early stages of pericardial effusion, or may experience dramatic hemodynamic compromise, as is seen with cardiac tamponade and constrictive pericarditis. There are many treatment options available that range from simple drainage to thoracic surgery. It is essential that the treating physician choose a treatment plan in the context of the cancer stage and the patient's prognosis. This article discusses the incidence, pathophysiology, clinical presentation, diagnosis, and treatment options in the various types of malignant pericardial disease.</p>","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"4 6","pages":"387-91"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/00132580-200211000-00008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22119371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An odyssey of a clinical researcher.","authors":"William H Frishman","doi":"10.1097/00132580-200211000-00009","DOIUrl":"https://doi.org/10.1097/00132580-200211000-00009","url":null,"abstract":"","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"4 6","pages":"392-6"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/00132580-200211000-00009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22120457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiac arrest associated with intravenous propofol during transesophageal echocardiography before DC cardioversion.","authors":"Edmund A Bermudez, Ming Hui Chen","doi":"10.1097/00132580-200211000-00004","DOIUrl":"https://doi.org/10.1097/00132580-200211000-00004","url":null,"abstract":"<p><p>Transesophageal echocardiography (TEE)-guided cardioversion has been utilized as a feasible alternative to conventional anticoagulation strategies in the management of patients with atrial fibrillation. As such, the use of intravenous sedation protocols using relatively short-acting anesthetics, such as propofol, have gained popularity in the outpatient and inpatient settings for such procedures. The authors report a case of cardiac arrest and electromechanical dissociation associated with the use of intravenous propofol during TEE before direct current cardioversion for atrial fibrillation.</p>","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"4 6","pages":"355-7"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/00132580-200211000-00004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22119369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Johann Auer, Markus Leitinger, Robert Berent, Wolfgang Prammer, Thomas Weber, Elisabeth Lassnig, Bernd Eber
{"title":"Influenza A and B IgG seropositivity and coronary atherosclerosis assessed by angiography.","authors":"Johann Auer, Markus Leitinger, Robert Berent, Wolfgang Prammer, Thomas Weber, Elisabeth Lassnig, Bernd Eber","doi":"10.1097/00132580-200211000-00003","DOIUrl":"https://doi.org/10.1097/00132580-200211000-00003","url":null,"abstract":"<p><p>Infectious agents, in particular intracellular pathogens that can establish long-term, persistent seropositivity, may play an important role in atherogenesis. The possible association between influenza type A and B infection and angiographically proven coronary artery disease (CAD) and the effect of the aggregate pathogen burden on CAD was studied by testing blood from 218 patients undergoing coronary angiography for serum IgG antibodies to influenza A and B, and for antibodies to four other pathogens (hepatitis A, Chlamydia pneumoniae, Helicobacter pylori, and cytomegalovirus). This analysis demonstrates that although influenza (A and B) seropositivity represents no predictor of risk for CAD, infectious burden is independently associated with coronary atherosclerosis.</p>","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"4 6","pages":"349-54"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/00132580-200211000-00003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22119366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comprehensive management of hypertensive emergencies and urgencies.","authors":"George A Mansoor, William H Frishman","doi":"10.1097/00132580-200211000-00005","DOIUrl":"https://doi.org/10.1097/00132580-200211000-00005","url":null,"abstract":"<p><p>Despite advances in chronic hypertension management, hypertensive emergencies and urgencies remain as serious complications. Much of this relates to poor compliance with effective antihypertensive management. Hypertensive emergencies and urgencies can also be seen as the initial manifestations of hypertension in pregnancy and in the perioperative period. Multiple classes of intravenous antihypertensive drugs are available to treat hypertensive emergencies, and specific agents may have an advantage in a given clinical situation. Orally active agents are used to treat hypertensive urgencies, and include clonidine, angiotensin-converting enzyme inhibitors, and labetalol. Most patients respond to drug therapy, but problems may arise related to a rapid normalization of blood pressure.</p>","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"4 6","pages":"358-71"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/00132580-200211000-00005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22119367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}