Scott Venter, Xiaoqiu Liu, Cherry Koh, Michael Solomon, Ruby Cole, Nicholas Hirst, Daniel Steffens
{"title":"The Power of Prehabilitation, the Reporting of Power Calculations in Randomized Clinical Trials Evaluating Prehabilitation in Cancer Surgery: A Systematic Review and Meta-research Study.","authors":"Scott Venter, Xiaoqiu Liu, Cherry Koh, Michael Solomon, Ruby Cole, Nicholas Hirst, Daniel Steffens","doi":"10.1016/j.apmr.2025.01.465","DOIUrl":"10.1016/j.apmr.2025.01.465","url":null,"abstract":"<p><strong>Objective: </strong>To assess sample size calculation reporting in randomized controlled trials (RCTs) investigating prehabilitation interventions in oncological surgery patients.</p><p><strong>Data sources: </strong>A systematic literature search was performed in multiple medical databases from inception to April 2023, including MEDLINE, Embase, The Cochrane Library, CINHAL, AMED, and PsychINFO.</p><p><strong>Study selection: </strong>The inclusion criteria used were RCTs evaluating effectiveness of exercise, nutrition, and/or psychological interventions on postoperative outcomes of adult patients undergoing oncological surgery.</p><p><strong>Data extraction: </strong>Two authors (DS and SV) extracted information on the sample size calculation parameters, including type I error (α), power (1-β), mean (or mean difference between randomization arms), and variance (eg, standard deviation) for continuous outcomes, and event rates or event rate difference between randomization arms for dichotomous outcomes. When possible, we recalculated the sample size required using the collected data, given a 10% margin of error.</p><p><strong>Data synthesis: </strong>Of the 59 included publications (58 RCTs), 26 (44%) reported sufficient information to complete sample size recalculation. Of those that provided sufficient information allowing us to recalculate the required sample size, 11 (42%) were within a 10% margin of the reported sample size, whereas 9 (35%) were >10% higher than reported sample size and 6 (23%) were >10% lower than reported sample size.</p><p><strong>Conclusions: </strong>Over half of the published RCTs in this field exhibit poor sample size calculation reporting. Most RCTs that report sufficient sample size information were underpowered. More stringent reporting requirements are necessary.</p>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Steven Kirshblum, Brittany Snider, Amanda Botticello, John Benedetto, Einat Engel-Haber
{"title":"The Role of Motor Zones of Partial Preservation in Conversion From Initially Complete to Motor Incomplete Spinal Cord Injury.","authors":"Steven Kirshblum, Brittany Snider, Amanda Botticello, John Benedetto, Einat Engel-Haber","doi":"10.1016/j.apmr.2025.01.473","DOIUrl":"10.1016/j.apmr.2025.01.473","url":null,"abstract":"<p><strong>Objective: </strong>To determine (1) the frequency of persons with spinal cord injury (SCI) presenting with a neurological complete injury (American Spinal Injury Association Impairment Scale [AIS] A) who would be classified as AIS C or D if sensory sacral sparing were present, and (2) if this status is associated with an increase in conversion to motor incomplete status on follow-up (6-24 months after injury).</p><p><strong>Design: </strong>Retrospective analysis of longitudinal data.</p><p><strong>Interventions: </strong>Not applicable.</p><p><strong>Setting: </strong>National SCI Model Systems data from 2011 to 2023.</p><p><strong>Participants: </strong>Persons with AIS A, initial International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) examination within 30 days of injury, motor level C1-L2, and aged ≥16 years at time of injury (N=2018).</p><p><strong>Main outcome measures: </strong>Motor levels of injury and the motor zones of partial preservation (ZPPs) were determined from the first postinjury examination. Motor levels were defined using both the ISNCSCI definition and an alternate definition (not deferring to sensory level when proximal myotomes [eg, C5] are intact). Individuals with a motor ZPP >3 levels below the motor level on either side were classified as \"motor incomplete-like.\" To evaluate conversion, AIS grades were determined from the follow-up examination (N=500).</p><p><strong>Analysis: </strong>Frequencies and proportions of persons with a \"motor incomplete-like\" status were evaluated to determine whether this classification was associated with conversion to a motor incomplete injury at follow-up.</p><p><strong>Results: </strong>Of the total sample (N=2018), using the ISNCSCI definition of motor levels, 12.7% (N=256) presented as \"motor incomplete-like,\" with the majority \"AIS C-like\" (75.4%; N=193). \"Motor incomplete-like\" status was more common in those with tetraplegia than paraplegia (18.2% vs 9.6%). Of the sample, 24.8% (N=500) had a follow-up examination. Those initially with a \"motor incomplete-like\" injury had a greater likelihood of conversion to motor incomplete status (AIS C or D) at follow-up compared with those without this designation (42.9% vs 13.1%). Using the \"alternate motor level\" definition, 9.6% (N=194) of individuals presented as \"motor incomplete-like,\" and the likelihood of conversion to motor incomplete status further increased (53.5% vs 13.3%).</p><p><strong>Conclusion: </strong>These findings highlight the importance of the initial motor ZPP in predicting AIS conversion after acute traumatic SCI. This can help identify patients with complete injuries who are more likely to undergo AIS conversion, particularly to motor incomplete status.</p>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicholas J Williams, Stephanie Liebert, Yadi Li, Kim Kalo, Brittany Lapin, Joshua K Johnson
{"title":"Interrater Reliability of the AM-PAC 6-Clicks Basic Mobility Short Form Between Nurses and Physical Therapists.","authors":"Nicholas J Williams, Stephanie Liebert, Yadi Li, Kim Kalo, Brittany Lapin, Joshua K Johnson","doi":"10.1016/j.apmr.2025.01.472","DOIUrl":"10.1016/j.apmr.2025.01.472","url":null,"abstract":"<p><strong>Objective: </strong>To examine the interrater reliability between nurse- and physical therapist (PT)-recorded scores from the Activity Measure for Post-Acute Care 6-Clicks Basic Mobility short form across hospitals, services, and categories of assessment timing.</p><p><strong>Design: </strong>Cross-sectional study of retrospective electronic health record data.</p><p><strong>Setting: </strong>Data were collected for patients in 11 hospitals between January 2020 and October 2022. Nurse- and PT-recorded 6-Clicks mobility scores were paired by date.</p><p><strong>Participants: </strong>There were 535,974 unique score pairs for 127,583 patients.</p><p><strong>Interventions: </strong>Not applicable.</p><p><strong>Main outcome: </strong>Interrater reliability was examined using intraclass correlation coefficients where values <0.5, 0.5-0.75, 0.75-0.9, and >0.9 indicate poor, moderate, good, and excellent reliability, respectively. In secondary analyses, score pairs were categorized according to: (1) hospital, (2) unit type (intensive care vs other), (3) clinical service, and (4) relative timing of nurse- and PT-recorded scores.</p><p><strong>Measures: </strong>6-Clicks Basic Mobility short form.</p><p><strong>Results: </strong>The interrater reliability was good overall, in 6 hospitals (moderate in 4 hospitals and poor in 1), in both intensive care and other units, for 4 out of 5 clinical services (moderate for 1), and for 4 out of 5 timing categories (moderate for 1).</p><p><strong>Conclusions: </strong>In this large study of real-world data, nurse- and PT-recorded 6-Clicks mobility scores had moderate-to-good interrater reliability.</p>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patricia C Heyn, Elizabeth A Terhune, Keshav Godha, Mark A Hirsch
{"title":"Protecting Your Health and Brain Against Climate Change: An Information Page for Older Adults.","authors":"Patricia C Heyn, Elizabeth A Terhune, Keshav Godha, Mark A Hirsch","doi":"10.1016/j.apmr.2025.01.418","DOIUrl":"10.1016/j.apmr.2025.01.418","url":null,"abstract":"","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dimitra V Pouliopoulou, Myranda Hawthorne, Joy C MacDermid, Nicole Billias, Erin Miller, Kieran Quinn, Simon Décary, Fahad A Razak, Angela Cheung, Panagis Galiatsatos, Tiago V Pereira, Pavlos Bobos
{"title":"Prevalence and Impact of Postexertional Malaise on Recovery in Adults With Post-COVID-19 Condition: A Systematic Review With Meta-analysis.","authors":"Dimitra V Pouliopoulou, Myranda Hawthorne, Joy C MacDermid, Nicole Billias, Erin Miller, Kieran Quinn, Simon Décary, Fahad A Razak, Angela Cheung, Panagis Galiatsatos, Tiago V Pereira, Pavlos Bobos","doi":"10.1016/j.apmr.2025.01.471","DOIUrl":"10.1016/j.apmr.2025.01.471","url":null,"abstract":"<p><strong>Objective: </strong>To assess the prevalence of postexertional malaise (PEM) in people with post-COVID-19 condition (PCC); and the change in prevalence of PEM after rehabilitation interventions in people with PCC.</p><p><strong>Data sources: </strong>We searched MEDLINE, Embase, CENTRAL, CINAHL, PsychINFO, and clinical trial registries from inception until February 11, 2025.</p><p><strong>Study selection: </strong>We included observational studies that measured the prevalence of PEM in adults with PCC and interventional studies that measured the change in prevalence of PEM after rehabilitation interventions in adults with PCC. Two independent researchers screened titles and abstracts. Any discrepancies underwent full text review. Two independent researchers screened the articles included at the full text level.</p><p><strong>Data extraction: </strong>Two independent researchers extracted data from eligible studies. We extracted point prevalence from the cross-sectional studies; and period prevalence from the longitudinal studies. Two independent reviewers assessed the risk of bias. Discrepancies were resolved with a senior research team member. For the prevalence studies we used the ROBINS-E tool. For randomized controlled trials we used the RoB2 tool. For non-randomized interventional studies we used the ROBINS-I tool to assess the non-randomized studies. We used the GRADE system to assess the certainty of the evidence.</p><p><strong>Data synthesis: </strong>We performed a single-arm proportional meta-analysis to synthesize prevalence estimates using logit transformation. We conducted a sensitivity analysis using multilevel-mixed-effects logistic regression. We used a random effects model. Results were reported as proportions with corresponding 95% confidence intervals (95% CI) or presented descriptively when statistical analysis was not applied. This study is registered with PROSPERO (CRD42024516682). The prevalence of PEM in community-dwelling adults living with PCC was 25% (95% CI: 0.17-0.36; 10 studies; 4,076 low certainty after the word participants). Five of the included studies (193 patients) found a decrease in the frequency and intensity of PEM episodes in adults with PCC after a tailored rehabilitation program centered on integrating pacing approaches. Eight studies (1080 patients) measured PEM as an adverse event following an individually tailored rehabilitation intervention with a therapeutic exercise component. Seven of these studies did not find indications of post exertional symptom exacerbation related to the exercise component of the intervention. All of the studies had high to very high risk of bias.</p><p><strong>Conclusions: </strong>Our research confirms that there is a large burden of PEM in adults living with PCC, highlighting a critical challenge for health care systems and an urgent need for more inclusive and rigorous research, to offer safe and effective therapeutic solutions and meet the variable needs of p","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alba Esteban-Simón MSc, David M. Díez-Fernández MSc, Manuel A. Rodríguez-Pérez PhD, Eva Artés-Rodríguez PhD, Alberto Soriano-Maldonado PhD
{"title":"Response to Letter to Editor: Does a Resistance Training Program Affect Between-Arms Volume Difference and Shoulder-Arm Disabilities in Female Breast Cancer Survivors? The Role of Surgery Type and Treatments. Secondary Outcomes of the EFICAN Trial","authors":"Alba Esteban-Simón MSc, David M. Díez-Fernández MSc, Manuel A. Rodríguez-Pérez PhD, Eva Artés-Rodríguez PhD, Alberto Soriano-Maldonado PhD","doi":"10.1016/j.apmr.2024.09.021","DOIUrl":"10.1016/j.apmr.2024.09.021","url":null,"abstract":"","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":"106 2","pages":"Page 322"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Archives I/EP Guidelines","authors":"","doi":"10.1016/S0003-9993(25)00020-6","DOIUrl":"10.1016/S0003-9993(25)00020-6","url":null,"abstract":"","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":"106 2","pages":"Pages 323-325"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daija A. Jackson MA , Aaron P. Turner PhD , Sarah A. Raskin PhD , Lindsay O. Neto MPH , Elizabeth S. Gromisch PhD
{"title":"Prospective Memory Complaints Are Related to Objective Performance in People With Multiple Sclerosis","authors":"Daija A. Jackson MA , Aaron P. Turner PhD , Sarah A. Raskin PhD , Lindsay O. Neto MPH , Elizabeth S. Gromisch PhD","doi":"10.1016/j.apmr.2024.08.018","DOIUrl":"10.1016/j.apmr.2024.08.018","url":null,"abstract":"<div><h3>Objectives</h3><div>To examine the association between subjective and objective prospective memory (PM) in people with multiple sclerosis (PwMS).</div></div><div><h3>Design</h3><div>Secondary analysis of a cross-sectional cohort study.</div></div><div><h3>Setting</h3><div>Community-based comprehensive multiple sclerosis center.</div></div><div><h3>Participants</h3><div>PwMS (N=112) who completed a battery that included measures of PM, depression, and fatigue.</div></div><div><h3>Interventions</h3><div>Not applicable.</div></div><div><h3>Main Outcome Measures</h3><div>Objective PM was measured with the performance-based Memory for Intentions Test (MIST), whereas subjective PM was assessed with the self-report Perceived Deficits Questionnaire-Prospective Memory (PDQ-PM).</div></div><div><h3>Results</h3><div>PwMS had low scores on the PDDS (median=2) and HADS-D (median=5.29), with 26.8% scoring 1 standard deviation or lower (≤15th percentile) on the MIST. Objective PM was significantly associated with subjective PM in a multivariate model (<em>β</em>=−0.18, <em>P</em>=.036), which accounted for demographics, physical disability, retrospective memory, and depressive and fatigue severity. Physical disability, depression, and fatigue were also significant contributors to subjective PM. Time-based PM performance emerged as the specific component that was associated with subjective PM.</div></div><div><h3>Conclusions</h3><div>These findings suggest that among PwMS with relatively mild impairment and symptomatology, their objective PM performance was associated with their self-assessments, even when considering retrospective memory and factors that influence their cognitive perceptions. The results expand upon the subjective-objective cognition discrepancy literature in multiple sclerosis and highlights how the PDQ-PM could be used as a complementary measure to help identify difficulties with PM.</div></div>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":"106 2","pages":"Pages 223-229"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor on “Does a Resistance Training Program Affect Between-Arms Volume Difference and Shoulder-Arm Disabilities in Female Breast Cancer Survivors? The Role of Surgery Type and Treatments”","authors":"Gurkirat Singh MPT, Sakshi Sadhu MPT, Anmol Bhatia MPT","doi":"10.1016/j.apmr.2024.08.028","DOIUrl":"10.1016/j.apmr.2024.08.028","url":null,"abstract":"","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":"106 2","pages":"Page 321"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editors' Selections From This Issue","authors":"","doi":"10.1016/S0003-9993(25)00008-5","DOIUrl":"10.1016/S0003-9993(25)00008-5","url":null,"abstract":"","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":"106 2","pages":"Page A8"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}