{"title":"Effect of Induced Anxiety on Respiratory Resistance Using Virtual Reality Simulation","authors":"M. Bohensky, A. Johnson, J. Vossoughi","doi":"10.4236/OJRD.2017.72008","DOIUrl":"https://doi.org/10.4236/OJRD.2017.72008","url":null,"abstract":"Background: The purpose of this research was to identify significant changes to respiratory resistance resulting from anxiety inducing simulations presented through the medium of virtual reality (VR) goggles. The tested hypothesis was that a virtual reality simulation would produce anxiety in the wearer, and, with it, a statistically significant change in subject respiratory resistance. It was also suggested that there may be a significant difference in the levels of respiratory resistance responses of males and females. The Oculus Rift DK2 VR goggles with video software designed for the Rift were used to induce anxiety in the wearers. Methods: Respiratory resistances in both inhalation and exhalation directions were measured with the Airflow Perturbation Device (APD), a medical instrument used noninvasively. Two groups of subjects were tested: the test group watched a simulation deemed to be anxiety inducing, and the Control group watched a simulation determined to be non-anxiety inducing. Anxiety levels and respiratory resistance were measured before and during the simulation with two anxiety measures, the State Trait Anxiety Inventory (STAI) and the Subjective Units of Distress Scale (SUDS). Results: Statistically significant increases in anxiety level and respiratory resistance were found in the Test group, but no significant differences in anxiety and respiratory resistance levels were found in the control group. Anxiety affected both breathing phases similarly. For the gender hypothesis, we found that one of the tests used to measure anxiety, (the SUDS difference) was statistically significant, while the other test and the difference in respiratory resistance were not statistically significant. Conclusion: Results from this experiment show that anxiety level can be a significant contributor to the physiological measurement of respiratory resistance, and this can have implications for pulmonary function test environments and the psychological conditions of the patients being tested.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"07 1","pages":"68-82"},"PeriodicalIF":0.0,"publicationDate":"2017-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49591125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Santhi, D. Ramsey, Gillian Phillipson, D. Hull, V. Revell, D. Dijk
{"title":"Efficacy of a Topical Aromatic Rub (Vicks VapoRub ® ) on Effects on Self-Reported and Actigraphically Assessed Aspects of Sleep in Common Cold Patients","authors":"N. Santhi, D. Ramsey, Gillian Phillipson, D. Hull, V. Revell, D. Dijk","doi":"10.4236/OJRD.2017.72009","DOIUrl":"https://doi.org/10.4236/OJRD.2017.72009","url":null,"abstract":"Common cold sufferers frequently report sleep disruption during the symptomatic period of infections. We examined the effects of treatment with a topical aromatic pharmaceutical ointment (Vicks VapoRub®), on associated sleep disturbances. The effects of Vicks VapoRub® versus placebo (petrolatum ointment) on subjective and objective measured sleep parameters were assessed in an exploratory study of 100 common cold patients, in a randomized, single blind, controlled, two-arm, parallel design study. The primary efficacy variable was subjective sleep quality measured with the SQSQ (Subjective Quality of Sleep Questionnaire). Additional measures included, ease of falling asleep and depth of sleep (measured with a post-sleep Visual Analog Scale), total sleep time, sleep onset latency, activity score, percentage of sleep, sleep efficiency (measured with actigraphy and SQSQ) and sleep quality index measured with a modified Karolinska Sleep Diary (KSD). The primary endpoint, “How was the quality of your sleep last night?” showed a statistically significant difference in change from baseline in favour of VapoRub treatment (p = 0.0392) versus placebo. Positive effects of VapoRub versus placebo were also observed for “How refreshed did you feel upon waking up?” (p = 0.0122) (SQSQ), “Did you get enough sleep?” (p = 0.0036) (KSD), “How was it to get up?” (p = 0.0120) (KSD) and “Do you feel well-rested?” (p = 0.0125) (KSD). No statistically significant changes from baseline versus placebo were detected in the Actiwatch endpoints. Vicks VapoRub® when applied before retiring to bed can reduce subjective sleep disturbances during a common cold. The results of this exploratory study support the belief among patients that the use of VapoRub improves subjective sleep quality during common cold which was associated with more refreshing sleep.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"07 1","pages":"83-101"},"PeriodicalIF":0.0,"publicationDate":"2017-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48612276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Kitada, S. Yasuda, N. Takahashi, S. Okazaki, K. Ishibashi, S. Hayashi, Y. Ohsaki
{"title":"Surgical Treatment of Idiopathic Multiple Pulmonary Arteriovenous Malformation Identified at the Onset of Cerebral Infarction: A Case Report","authors":"M. Kitada, S. Yasuda, N. Takahashi, S. Okazaki, K. Ishibashi, S. Hayashi, Y. Ohsaki","doi":"10.4236/OJRD.2017.72007","DOIUrl":"https://doi.org/10.4236/OJRD.2017.72007","url":null,"abstract":"Pulmonary arteriovenous malformation (PAVM), which is asymptomatic in most cases, is often identified in patients with central nervous system disorders such as brain abscesses and/or cerebral infarctions. We have reported a patient with idiopathic multiple PAVM identified at the onset of cerebral infarction. A 69-year-old woman visited the Department of Neuropathic Internal Medicine at our hospital with chief complaints of numbness in her left hand and a feeling of weakness. The patient was given a diagnosis of subacute cerebral infarction. Multiple old lacunar infarctions were also observed in the deep white matter of the left frontal lobe. Chest computed tomography showed multiple nodular structures, mainly in the right lower lung field (S8), as well as continuous arteries and veins at the site; thus, the patient was finally diagnosed with multiple PAVM. Right lower thoracoscopic lobectomy was performed, as is typical surgical practice in such cases. The patient had a favorable postoperative course, and had no recurrence of cerebral infarction. Although the patient’s lesions were mainly restricted to S8, the fact that there were multiple lesions deemed a lobectomy as the appropriate course of treatment. This case emphasizes that attention should be paid to cases of multiple PAVM since cerebral infarction may arise from the disease.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"07 1","pages":"62-67"},"PeriodicalIF":0.0,"publicationDate":"2017-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43485105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of ColdZyme Mouth Spray against Common Cold in Elderly Care Personnel","authors":"Mats Clarsund, C. Persson","doi":"10.4236/OJRD.2017.71002","DOIUrl":"https://doi.org/10.4236/OJRD.2017.71002","url":null,"abstract":"ColdZyme® Mouth Spray (ColdZyme) is a mouth spray intended to reduce the probability of catching a cold and/or can help shorten the duration of a cold if used at an early stage of the infection, by forming a barrier on the pharyngeal mucous membrane. This study evaluated the preventative effect of ColdZyme on common cold infections in personnel at elderly care facilities, and assessed the level of reduction in corresponding sick leave. The number of sick-leave days for the personnel decreased from an average of 5.2 days to 3.7 days (29%) when using ColdZyme compared to control period (p = 0.054). 63% of those who had a cold reported the symptoms to be milder than previous colds. Conclusion: Using ColdZyme® Mouth Spray to apply a barrier to the oropharynx may be an easy and practical way to prevent or reduce infections of the common cold virus and corresponding sick leave in personnel working in elderly care.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"94 1","pages":"12-17"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70584253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Observational Study of a Multi-Active Ingredient Over-the-Counter Cold Remedy Following Active Pharmacist Recommendation","authors":"Gillian Phillipson, J. Hull, B. Samoliński","doi":"10.4236/OJRD.2017.71005","DOIUrl":"https://doi.org/10.4236/OJRD.2017.71005","url":null,"abstract":"Real-world user satisfaction with a fixed dose combination over-the-counter cold remedy (Vicks Symptomed Complete Cytrynowy hot drink; VSCC) was evaluated in a prospective, non-comparative, observational study involving 176 pharmacies in Poland from February to April 2015. 1391 participants completed a questionnaire in the pharmacy and several paper questionnaires at home following use of the product at their own discretion. Participants returned their completed questionnaires to the pharmacy. 1356 participants were included in the intent-to-treat analysis. Participants highly valued the advice from their pharmacist (97%, P < 0.0001, important vs. not important) and thought the quality of that advice was good (93%, P < 0.0001, good/very good vs. very bad-fair). 96% of participants found VSCC to be effective in some way against their cold symptoms (P < 0.0001, effective vs. not effective) and 68% of them stated that it was better than any other cold therapy they had used before (P < 0.0001, better/best vs. same/worse). Adverse event reporting was very low.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"07 1","pages":"41-52"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70583944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nava Azimzadeh, M. Baram, N. Cavarocchi, H. Hirose
{"title":"Prone position: Does it help with acute respiratory distress syndrome (ARDS) requiring extracorporeal membrane oxygenation (ECMO)?","authors":"Nava Azimzadeh, M. Baram, N. Cavarocchi, H. Hirose","doi":"10.4236/OJRD.2017.71003","DOIUrl":"https://doi.org/10.4236/OJRD.2017.71003","url":null,"abstract":"Introduction: Lung protective ventilation therapy with low tidal volume-high PEEP is the standard treatment for the patients with acute respiratory distress syndrome (ARDS). Oscillators are occasionally used for salvage ventilation in cases where poor compliance restricts the use of traditional ventilation with ARDS. In addition to ventilator therapy, prone positioning has been used to improve oxygenation. We presented a challenging case of ARDS, which failed medical management extracorporeal membrane oxygenation (ECMO) support and oscillatory ventilation. Prone positioning was initiated which improved oxygenation, respiratory compliance and posterior atelectasis. Case presentation: A 41-year-old morbid obese female developed ARDS due to influenza pneumonia. The patient remained hypoxic despite optimum medical and ventilator management and required veno-venous extracorporeal membrane oxygenation (VV ECMO). CT scan of the chest showed ARDS with posterior consolidation. Despite ARDSnet ventilation support, antiviral therapy and ECMO support, there was no clinical improvement. High frequency oscillatory ventilation was initiated on ECMO day #13, which resulted in no respiratory improvement over the next 5 days. On ECMO day #18, the patient was placed on a Rotaprone® bed Therapy, utilizing a proning strategy of 16 hours a day. The clinical improvements observed were resolving of the consolidation on CXR, improvements in ventilatory parameters and decreased oxygen requirements. The patient was successfully weaned off ECMO on POD#25 (8 days post prone bed). Conclusions: Prone position improved oxygen saturation and pulmonary compliance in severe ARDS requiring ECMO and it might facilitate early weaning.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"07 1","pages":"18-24"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70584305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aspirin plus Pseudoephedrine (Aspirin Complex) for the Treatment of Symptoms of Upper Respiratory Tract Infection","authors":"M. Voelker, R. Eccles, U. Gessner","doi":"10.4236/OJRD.2017.71004","DOIUrl":"https://doi.org/10.4236/OJRD.2017.71004","url":null,"abstract":"Upper respiratory tract infections or common colds are a multi-symptom disease which is usually symptomatically treated with fixed dose multi-active ingredient medicinal products which are commonly used as non-prescription and over the counter. However, the active ingredients combined require a particular and clinically sound justification. Analgesics and decongestant can be combined to treat simultaneously the prominent symptoms cold-related pain (e.g. headache, muscle aches and pains), fever, inflammationand nasal/sinus congestion. This overview provides a summary of the evidence supporting the combination of acetylsalicylic acid (aspirin) and pseudoephedrine available in the common cold product Aspirin® Complex.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"07 1","pages":"25-40"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70584354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Kobashi, M. Kittaka, K. Mouri, Shigeki Kato, M. Oka
{"title":"Clinical Analysis of Pulmonary Nontuberculous Mycobacterial Disease Complicated by Lung Cancer during the Follow-Up Periods","authors":"Y. Kobashi, M. Kittaka, K. Mouri, Shigeki Kato, M. Oka","doi":"10.4236/OJRD.2016.64009","DOIUrl":"https://doi.org/10.4236/OJRD.2016.64009","url":null,"abstract":"Introduction: The objective of this study was the estimation of the clinical characteristics of patients with pulmonary nontuberculous mycobacterial (NTM) disease complicated by lung cancer during the follow-up periods. Methods: We analyzed the clinical findings of four patients (2.0%) complicated by lung cancer during the follow-up periods of over six months at least after the definite diagnosis of pulmonary NTM disease of 202 patients with pulmonary NTM disease experienced in our hospital in the last decade. Results: There were four patients with pulmonary NTM disease complicated by lung cancer and all of them were caused by Mycobacterium avium complex (MAC). They were all elderly male patients and had underlying diseases. Three patients were diagnosed with primary lung cancer and one diagnosed with metastatic lung cancer from colon cancer within 3 years after the diagnosis of pulmonary NTM disease. The treatments for lung cancer were surgical resection for all patients with localized lesions. One patient died due to the worsening of underlying disease and the remaining three survived except for the recurrence of one patient. Conclusion: Although the complication rate of pulmonary NTM disease and lung cancer was a lower percentage (2.0%) than in previous reports, the careful follow-up for patients with pulmonary NTM disease without forgetting the possible complication of lung cancer is necessary.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"06 1","pages":"59-66"},"PeriodicalIF":0.0,"publicationDate":"2016-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70583987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Aslam, J. Man, J. Behary, J. Riskallah, S. Ansary, B. Kwan
{"title":"Outcomes and Cost Effectiveness of a Respiratory Coordinated Care Program in Patients with Severe or Very Severe COPD","authors":"S. Aslam, J. Man, J. Behary, J. Riskallah, S. Ansary, B. Kwan","doi":"10.4236/OJRD.2016.63008","DOIUrl":"https://doi.org/10.4236/OJRD.2016.63008","url":null,"abstract":"Multidisciplinary community coordinated care programs are widely adopted to optimise care of \u0000chronic disease patients, but there is a need for further evaluation in the setting of COPD. This observational \u0000study evaluated 147 patients with severe or very severe COPD who were enrolled in a \u0000multidisciplinary community respiratory coordinated care program (RCCP) from 2007 to 2012. \u0000Comparison was made of hospitalisation rates and length of stay for 12 months prior to joining the \u0000program, and the first 12 months after joining the program. This data was used to inform a cost \u0000analysis. Enrolment into RCCP halved the annual hospital admission rate from 1.18 to 0.57 admissions \u0000per year (relative risk reduction 51.4%, p < 0.001), and annual total length of stay was reduced \u0000from 8.06 to 3.59 days per patient per year (p < 0.001). Hospital admissions were reduced \u0000from 5.05 days to 2.00 days (p < 0.001). Accounting for the program’s costs, these changes resulted \u0000in a $US 906.94 ($AUD 972.80) cost saving per patient per year. A RCCP program can reduce patient \u0000hospitalisation and overall costs in the COPD setting.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"06 1","pages":"52-57"},"PeriodicalIF":0.0,"publicationDate":"2016-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70584347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Chia, A. Chia, David Wang, Rabiha El-Habbal, Deren Sinkowitz
{"title":"Chronic Enterovirus D68 Bronchiolitis Causing Severe Respiratory Insufficiency","authors":"J. Chia, A. Chia, David Wang, Rabiha El-Habbal, Deren Sinkowitz","doi":"10.4236/OJRD.2016.63007","DOIUrl":"https://doi.org/10.4236/OJRD.2016.63007","url":null,"abstract":"Human enteroviruses are less well-known causes of acute bronchiolitis. In recent years, Enterovirus \u0000D68 [EV D68] has emerged as significant cause of epidemic viral bronchiolitis and pneumonia \u0000in the United States and other countries. Chronic bronchiolitis has not been previously attributed \u0000to EV D68. We documented EV D68 in open lung biopsies of a young adult patient who was frequently \u0000admitted to the hospital for severe exacerbation of respiratory infections and subsequently \u0000developed progressive respiratory insufficiency. The difficulty of diagnosis and potential \u0000economic impact of this illness is discussed.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"06 1","pages":"47-51"},"PeriodicalIF":0.0,"publicationDate":"2016-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70584327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}