The Journal of respiratory diseases最新文献_第2页

Pulmonary Misfortune Ensuing to Petroleum Related Employments 石油相关工作的肺心病

The Journal of respiratory diseases Pub Date : 2020-04-03 DOI: 10.4236/OJRD.2020.102003

M. Awadallah, T. Abdelgawad, Mohammed A Shendy, A. Al-Shenqiti, A. Abumossalam

{"title":"Pulmonary Misfortune Ensuing to Petroleum Related Employments","authors":"M. Awadallah, T. Abdelgawad, Mohammed A Shendy, A. Al-Shenqiti, A. Abumossalam","doi":"10.4236/OJRD.2020.102003","DOIUrl":"https://doi.org/10.4236/OJRD.2020.102003","url":null,"abstract":"Background: toxic gases and fumes prompted from petrol and gas stations imply their disabling and deadly risks on human lungs. Aim of Work: The aim of this work was to assess the pulmonary function derangements in petrol pump workers at Al-Medina Al-Munawara city. Patients and Methods: This cross sectional study was conducted on 189 cases out of them in control group (group I) with age and sex matched healthy adult males gathered from nonsmokers students and employees in Taibah University. The study group (group II) comprised of 89 males who were working in different petrol pump stations. History, clinical examination and pulmonary functional assessment were carried out by using portable spirometry, Co detector and puls oximeter. Results: The study’s results showoed that the lung function parameters (FEV1, FVC, PEFR, FEFR25% - 75%) were significantly reduced in petrol pump workers (Group II) as compared to the values for these parameters in subjects belonging to Group II (Control group), Similar findings were observed in previous studies on pulmonary functions in petrol-pump workers. This finding specified the restrictive nature of pulmonary involvement in the study group. Measurement of the exhaled CO was slightly higher in Group II than Group I. Conclusion: Fuel vapors and fumes in petrol stations showed direct incapacitating impact on workers pulmonary functions regarding spirometric measurements showing predominantly restrictive pattern and to less extent obstructive. Exhaled CO level was higher in addition to hypoxemia identified in these cases.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"10 1","pages":"21-31"},"PeriodicalIF":0.0,"publicationDate":"2020-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49528158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic Value of Leukocyte Count Abnormalities in Newly Diagnosed Tuberculosis Patients 白细胞计数异常对新诊断结核病的诊断价值

The Journal of respiratory diseases Pub Date : 2020-01-01 DOI: 10.4236/ojrd.2020.101001

B. H. M. Ngahane, Abinkeng Tazifua Ebenezer, Ngouadjeu Dongho Tsakeu Eveline, Mafo Nzonteu Estelle Raïssa, Kemta Lekpa Fernando, C. Lum, N. L. Henry

{"title":"Diagnostic Value of Leukocyte Count Abnormalities in Newly Diagnosed Tuberculosis Patients","authors":"B. H. M. Ngahane, Abinkeng Tazifua Ebenezer, Ngouadjeu Dongho Tsakeu Eveline, Mafo Nzonteu Estelle Raïssa, Kemta Lekpa Fernando, C. Lum, N. L. Henry","doi":"10.4236/ojrd.2020.101001","DOIUrl":"https://doi.org/10.4236/ojrd.2020.101001","url":null,"abstract":"Background: The diagnosis of tuberculosis (TB) is frequently challenging given that the clinical and radiographic features of TB are often nonspecific. Altered leukocyte count ratios could serve as new tools of diagnostic orientation of tuberculosis. The aim of this study was to assess the diagnostic value of the leukocyte count ratios for the diagnosis of TB. Methods: This was a cross-sectional study including cases of newly diagnosed TB patients from registers of the TB treatment center of the Douala General Hospital. Control subjects were healthy volunteers, age and sex matched, recruited at the blood bank. Sociodemographic, clinical data and peripheral blood parameters were collected. The diagnostic value of leukocyte counts was determined using receiver operating characteristics curve analysis. Results: In total, 204 TB patients and 204 control subjects were included in the study. The gender of the participants was equitably distributed in the 2 study groups (male 61.8%; female 38.2%). The median age of TB patients was 33 years while that of control patients was 32 years. The monocyte-lymphocyte count ratio (MLR) and neutrophil-lymphocyte count ratio (NLR) were significantly higher in the TB patients group compared to control group. A NLR >1.19 and MLR >0.29 were identified as cut-off values for discriminating TB patients. The areas under the curves (AUC) were 0.77 and 0.84 for the MLR and NLR respectively. Conclusion: A raised NLR > 1.19 and MLR > 0.29 are predictive of tuberculosis. The NLR has greater diagnostic ability as evidenced by its higher AUC. Further research is needed to confirm or refute our findings.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"32 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70583998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Pulmonary Hypoplasia: A Rare Cause of Chronic Cough in TB Endemic Area 肺发育不全:结核病流行地区慢性咳嗽的罕见病因

The Journal of respiratory diseases Pub Date : 2019-01-17 DOI: 10.4236/OJRD.2019.91002

Ouattara Khadidia, Kanouté Tenin, Baya Bocar, S. Dianguina, Kamian Youssouf Mama, S. Youssouf, Fofana Aminata, Traoré Mohamed Maba, Guindo Ibrahim, Sidibe Fatoumata, Dakouo Aimé Paul, S. F. Bintou, Bamba Salimata, Coulibaly Lamine, Yossi Oumar, Koné Samba, T. Yacouba

{"title":"Pulmonary Hypoplasia: A Rare Cause of Chronic Cough in TB Endemic Area","authors":"Ouattara Khadidia, Kanouté Tenin, Baya Bocar, S. Dianguina, Kamian Youssouf Mama, S. Youssouf, Fofana Aminata, Traoré Mohamed Maba, Guindo Ibrahim, Sidibe Fatoumata, Dakouo Aimé Paul, S. F. Bintou, Bamba Salimata, Coulibaly Lamine, Yossi Oumar, Koné Samba, T. Yacouba","doi":"10.4236/OJRD.2019.91002","DOIUrl":"https://doi.org/10.4236/OJRD.2019.91002","url":null,"abstract":"Pulmonary hypoplasia is a rare disease characterized by a defect of lung development more often unilateral. The diagnosis requires several exams to eliminate other causes of pulmonary retraction. We report two cases at the department of pneumophtisiology of the University Teaching Hospital of Point G. The first case is a young adult who was complaining of a chronic cough. Etiological investigation required several exams including spirometry and Computed tomographic scan (CT scan). After elimination of all suspected causes of pulmonary opacity, the diagnosis of pulmonary hypoplasia was retained. The second case is a 2-year-old girl who was born with congenital cardiopathy whose respiratory complications were increasing during her childhood and respiratory explorations discovered pulmonary agenesis. Pulmonary hypoplasia is rare in our medical practice, but attention must be drawn to a retractile pulmonary opacity in young age after elimination of all infectious causes in TB endemic area.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"9 1","pages":"18-25"},"PeriodicalIF":0.0,"publicationDate":"2019-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47779935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Several Dengue: About 2 Cases with Pulmonary Disease 几种登革热——附2例肺部疾病

The Journal of respiratory diseases Pub Date : 2018-09-28 DOI: 10.4236/ojrd.2018.84007

A. Konan, M. Aké-Assi, B. Kouadio, T. Eboua, A. Sétchéou, G. Diarrassouba, K. N’goran

{"title":"Several Dengue: About 2 Cases with Pulmonary Disease","authors":"A. Konan, M. Aké-Assi, B. Kouadio, T. Eboua, A. Sétchéou, G. Diarrassouba, K. N’goran","doi":"10.4236/ojrd.2018.84007","DOIUrl":"https://doi.org/10.4236/ojrd.2018.84007","url":null,"abstract":"The most widespread arbovirus in the world, dengue fever has been rampant since the 18th century. Since then, several epidemics have been documented in Asia, the Caribbean, South America and Africa. The authors report two cases of dengue fever in children aged six (6) and twelve (12) years respectively. The diagnosis of several dengue pulmonary was retained in these children, clinico-radiological and biological arguments. In addition to the hemorrhagic syndrome, the pulmonary symptomatology associated cough, dyspnea. Chest X-ray revealed bilateral and extensive alveolar interstitial radiological lesions. From a biological point of view, the positivity of dengue-specific IgM has confirmed arboviruses. From the diagnostic peculiarities of the cases observed, the authors suggest the search for factors associated with a primary dengue infection from several onsets to pulmonary manifestation in children. Indeed, this fringe of the population is no longer concerned with acute respiratory infections. In addition, the socio-cultural context of poverty, of pre-hospital therapeutic itinerary favoring traditional medicine, delays hospital care.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"08 1","pages":"63-68"},"PeriodicalIF":0.0,"publicationDate":"2018-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45364991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transbronchial Lung Cryobiopsy in the Diagnosis of Interstitial Lung Diseases. Looking at the Holy Grail or Another Misleading Diagnostic Approach 经支气管肺冷冻活检在间质性肺疾病诊断中的应用。寻找圣杯或另一种错误的诊断方法

The Journal of respiratory diseases Pub Date : 2018-09-27 DOI: 10.4236/OJRD.2018.84008

I. Sotiriou, A. Konstantinidou

引用次数: 0

Solitary Endobronchial Papilloma Mimicking a Neoplastic Lesion 孤立支气管内乳头状瘤似肿瘤病变

The Journal of respiratory diseases Pub Date : 2018-08-16 DOI: 10.4236/ojrd.2018.83005

Smadhi Hanen, Khalfallah Ikbel, Diouani Mohamed Fethi, A. Mahdi, Attia Monia, A. Aida, Megdiche Mohamed Lamine

引用次数: 0

Open-Label Real-World Pharmacy Purchaser Study of Two Fixed-Dose Combination OTC Cold Treatments; Wick MediNait, Wick DayMed Capsules or a Combination of Both 两种固定剂量组合OTC感冒治疗的开放标签真实世界药房购买者研究；Wick MediNait、Wick DayMed胶囊或两者的组合

The Journal of respiratory diseases Pub Date : 2018-08-13 DOI: 10.4236/ojrd.2018.83006

Gillian Phillipson, D. Ramsey, S. Aspley, I. Fietze

{"title":"Open-Label Real-World Pharmacy Purchaser Study of Two Fixed-Dose Combination OTC Cold Treatments; Wick MediNait, Wick DayMed Capsules or a Combination of Both","authors":"Gillian Phillipson, D. Ramsey, S. Aspley, I. Fietze","doi":"10.4236/ojrd.2018.83006","DOIUrl":"https://doi.org/10.4236/ojrd.2018.83006","url":null,"abstract":"Acute upper respiratory tract infections, i.e. common colds cause multiple symptoms and affect adults on average 2 - 4 times a year and children 6 - 8 times per year. Thousands of non-prescription, over-the-counter products are used by sufferers, aimed at relieving the various both er some symptoms such as cough, nasal congestion, sore throat, etc. This study evaluated real-world effectiveness of Wick MediNait or Wick DayMed medicines alone and together in a combination as a day and night treatment regimen. Adult cold sufferers were recruited in pharmacy by pharmacy staff following self-purchase of either Wick MediNait, Wick DayMed capsules, or the combination of DayMed and MediNait. Participants completed online questionnaires before and after product use (evening of the first day for DayMed and the morning after using MediNait at bedtime). For the primary endpoint “Wick MediNait was effective at relieving my symptoms”, there was a statistically significant difference (p < 0.0001) in the users who Strongly Agreed or Agreed vs. Neither Agreed or Disagreed, Disagreed or Strongly Disagreed. Further, all symptoms evaluated (cough, runny nose, nasal congestion, fever, headache, sore throat, muscle aches and pains, sneezing) were statistically improved after MediNait and DayMed alone and when both were used, and users were satisfied with both treatments. All treatments were well tolerated with minimal adverse event reporting. The diurnal use of DayMed capsules combined with the nocturnal use of MediNait allows cold sufferers to efficiently self-manage their symptom relief throughout the day and night.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"08 1","pages":"43-62"},"PeriodicalIF":0.0,"publicationDate":"2018-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49147683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unusual Location of Coelomic Cysts 体腔囊肿的异常位置

The Journal of respiratory diseases Pub Date : 2018-08-13 DOI: 10.4236/OJRD.2018.83004

Smadhi Hanen, B. Emna, Diouani Mohamed Fethi, A. Mahdi, Attia Monia, A. Aida, Megdiche Mohamed Lamine

引用次数: 0

User Experience of ColdZyme Mouth Spray against Common Cold in Competitive Athletes ColdZyme口腔喷雾剂对抗竞技运动员感冒的用户体验

The Journal of respiratory diseases Pub Date : 2018-04-09 DOI: 10.4236/OJRD.2018.82002

U. Blom, I. Nelson

{"title":"User Experience of ColdZyme Mouth Spray against Common Cold in Competitive Athletes","authors":"U. Blom, I. Nelson","doi":"10.4236/OJRD.2018.82002","DOIUrl":"https://doi.org/10.4236/OJRD.2018.82002","url":null,"abstract":"ColdZyme® Mouth Spray (ColdZyme) is intended to reduce the probability of catching a cold and/or can help shorten the duration of a cold, if used at an early stage of the infection, by forming a barrier on the pharyngeal mucous membrane. The user experience of ColdZyme on naturally occurring common cold infections was evaluated in competitive athletes training professionally or on an amateur level. Thirteen athletes completed weekly electronic surveys on occurrence of common colds, cold severity and user experience over the course of 3 months. The 13 participants reported in total 15 cold incidents with an average duration of 7.4 days. The average cold severity was 31.2 on a visual-analogue scale (VAS) ranging from 0 (mildest possible cold) to 100 (worst possible cold). The overall user satisfaction with ColdZyme was high. 81% of the reported colds were experienced to be milder and/or shorter than usual. None of the participants reported “No effect”. Out of the participants who reported absence of a cold in the previous week, 69% reported a positive answer to the question if ColdZyme had prevented them from catching a cold in the previous week. Conclusion: The present study evaluated prevention and alleviation of naturally occurring common cold in athletes, and demonstrated that ColdZyme may be an easy and practical way for competitive athletes to prevent or reduce infections of the common cold virus and corresponding unwanted absence from training and competition. Due to the lack of a comparator group, a placebo effect cannot be excluded.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"8 1","pages":"13-20"},"PeriodicalIF":0.0,"publicationDate":"2018-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44105021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Evaluation of Asthma Symptoms to Assess Asthma Control Status in a Primary Care Setting: An Exploratory Analysis of Pooled Data from Three Trials 在初级保健环境中评估哮喘症状以评估哮喘控制状况:对三个试验汇总数据的探索性分析

The Journal of respiratory diseases Pub Date : 2018-04-09 DOI: 10.4236/OJRD.2018.82003

S. Hozawa, M. Terada, Maki Hozawa

{"title":"Evaluation of Asthma Symptoms to Assess Asthma Control Status in a Primary Care Setting: An Exploratory Analysis of Pooled Data from Three Trials","authors":"S. Hozawa, M. Terada, Maki Hozawa","doi":"10.4236/OJRD.2018.82003","DOIUrl":"https://doi.org/10.4236/OJRD.2018.82003","url":null,"abstract":"Background: Primary care physicians in Japan see many patients in a given day; consequently, they find it challenging to devote sufficient time for detailed clinical consultation and evaluation of asthma control status. The aim of this study was to investigate asthma symptoms that reveal the presence of inadequately controlled asthma. Methods: A pooled analysis of baseline data from 100 patients with asthma treated with inhaled corticosteroid(s) (ICS) alone or ICS/long-acting beta-agonist who participated in three previous clinical trials was performed. Asthma control status and asthmatic symptoms were determined using a five-item Asthma Control Questionnaire, and whether asthmatic symptoms reflect clinical markers was investigated. Results: Nocturnal awakening owing to asthmatic symptoms was observed only in the uncontrolled asthma group. Patient-reported wheezing was not observed in the group with well-controlled asthma, but was observed in all patients in the uncontrolled asthma group. Virtually all patients, irrespective of asthma control status, reported symptoms in the morning, limitation of normal daily activities, and shortness of breath. Conclusions: The presence of nocturnal awakening due to asthma and wheezing likely reflected uncontrolled asthma. These results will lead to re-recognition that clinical interview, querying nocturnal awakening from asthma and wheezing is a simple and useful approach to assess asthma control status in a primary care setting.","PeriodicalId":83134,"journal":{"name":"The Journal of respiratory diseases","volume":"08 1","pages":"21-32"},"PeriodicalIF":0.0,"publicationDate":"2018-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42876173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0