Archives of Medicine and Health Sciences最新文献_第9页

Role of epigenetics variation with focus on DNA Methylation in triple-negative breast cancer patients 以DNA甲基化为重点的表观遗传学变异在癌症三阴性患者中的作用

Archives of Medicine and Health Sciences Pub Date : 2023-01-01 DOI: 10.4103/amhs.amhs_195_22

G. Reddy, V. Brahmaiah, B. Kavitha, Jaya Nethagani, E. Palaparthi, R. Lebaka, G. Deepika

引用次数: 1

Study of prevalence, microbiologic agents, and bladder management methods of urinary tract infections among spinal cord injury patients 脊髓损伤患者尿路感染流行病学、微生物制剂及膀胱管理方法的研究

Archives of Medicine and Health Sciences Pub Date : 2023-01-01 DOI: 10.4103/amhs.amhs_45_23

K. Ashta, C. Mohan, B. Nair, S. Arora

{"title":"Study of prevalence, microbiologic agents, and bladder management methods of urinary tract infections among spinal cord injury patients","authors":"K. Ashta, C. Mohan, B. Nair, S. Arora","doi":"10.4103/amhs.amhs_45_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_45_23","url":null,"abstract":"Background and Aim: Spinal cord injury (SCI) patients have an increased risk of developing urinary tract infections. The method of bladder drainage influences the risk of urinary tract infection (UTI), and most persons with SCI on per urethral continuous catheterization (CC) or clean intermittent catheterization (CIC) develop urinary tract infection. Identification and treatment of severe UTI with appropriate antibiotics as early as possible is associated with better outcomes in SCI patients. The aim of this study was to determine the prevalence and causative organisms of symptomatic urinary tract infection in spinal cord injury patients with different bladder management methods. Materials and Methods: A total of 50 patients with SCI were followed up at a rehabilitation centre from Jan 2020 to Dec 2021 in a prospective descriptive study. The demographic status, clinical and laboratory findings of the patients with SCI were studied and the prevalence and causative organisms of symptomatic UTI in these patients with different bladder management methods were analysed. Results: The commonest organisms isolated were E. coli (31%), Pseudomonas (29%) and Klebsiella (21%). The organisms isolated in the UTI were most sensitive to colistin (82%), followed by 59% being sensitive to both imipenem and tigecycline. Least sensitivity was seen to Piperacillin, Ceftriaxone and Levofloxacin. Maximum UTI episodes were seen in cases with CC followed by CIC. Least UTI episodes were seen in cases where supra-pubic cystostomy was done followed by patients who were self-urinating. Conclusion: Symptomatic UTI in SCI patients is more prevalent in patients with CC and CIC. Such patients should be started as early as possible on antibiotics depending on the antibiotic sensitivity pattern of the organisms isolated.","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":"11 1","pages":"64 - 69"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47891049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Penile paraffinoma 石蜡阴茎

Archives of Medicine and Health Sciences Pub Date : 2023-01-01 DOI: 10.4103/amhs.amhs_274_22

N. Gupta, K. Sarin, Lav Behl, Sanjeev Uppal

引用次数: 0

A study of E-cadherin expression in esophageal carcinoma 食管癌组织中e -钙粘蛋白表达的研究

Archives of Medicine and Health Sciences Pub Date : 2023-01-01 DOI: 10.4103/amhs.amhs_100_23

CP Manjula, B Meghana

{"title":"A study of E-cadherin expression in esophageal carcinoma","authors":"CP Manjula, B Meghana","doi":"10.4103/amhs.amhs_100_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_100_23","url":null,"abstract":"Background and Aim: Esophageal carcinoma is one of the most aggressive malignancies of the gastrointestinal tract. E-cadherin is a transmembrane glycoprotein and its expression is associated with tumor invasiveness, metastasis, survival, and prognosis. The present study aims to compare the pattern of E-cadherin expression in esophageal carcinoma. Materials and Methods: This is a retrospective study conducted over a period of 5 years. Expression of E-cadherin was evaluated on paraffin-embedded sections of esophageal carcinoma. The immunoreactive scores (IRSs) were calculated and compared with tumor differentiation. Results: The present study included 45 esophageal biopsies, of which 40 cases were neoplastic and 5 were nonneoplastic. The most common histological type is squamous cell carcinoma (SCC), of which well-differentiated SCC (WDSCC) was 12.5%, moderately differentiated SCC 57.5%, and poorly differentiated SCC (PDSCC) 17.5%. The IRS was highest in WDSCC and least in PDSCC, with a mean score of 7.20 and 1.57, respectively. This difference was statistically significant with P = 0.001. Conclusion: E-cadherin is an important prognostic marker in esophageal SCC. Its expression is inversely correlated with tumor differentiation. WDSCC and AC exhibit strong E-cadherin expression. Reduced expression of E-cadherin is more likely to be associated with PDSCC of the esophagus.","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135007912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Consequences of the epidemiologic transition in Kerala, India – A public–private-partnership model of health care: A critical analysis 印度喀拉拉邦流行病学转变的后果——卫生保健的公私伙伴关系模式:批判性分析

Archives of Medicine and Health Sciences Pub Date : 2023-01-01 DOI: 10.4103/amhs.amhs_2_23

JaideepC Menon, Aswathy Sreedevi, Chandrashekar Janakiram

{"title":"Consequences of the epidemiologic transition in Kerala, India – A public–private-partnership model of health care: A critical analysis","authors":"JaideepC Menon, Aswathy Sreedevi, Chandrashekar Janakiram","doi":"10.4103/amhs.amhs_2_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_2_23","url":null,"abstract":"The state of Kerala stands out as having the highest prevalence of diabetes and coronary artery disease in comparison to other states within India. This observation positions India as the global epicenter for noncommunicable diseases (NCDs), specifically diabetes, and cardiovascular ailments. Kerala is in a highly advanced stage of epidemiological transition, surpassing other states in India. This transition is characterized by factors such as an aging population, a high incidence of NCDs, and elevated levels of morbidity. Kerala boasts a robust health-care system encompassing a strong public sector, further reinforced by a network of private hospitals spread across the state. Moreover, the population of Kerala possesses a high literacy rate. It is well-informed about their rights, while local self-governance and nongovernmental organizations (NGOs) actively collaborate to promote community health. These factors have collectively contributed to the state’s proactive approach toward addressing NCDs. In the domains of surveillance, monitoring, and prevention of NCDs, as well as the prevention of complications arising from these diseases, Kerala has implemented various schemes across the public, private, and NGO sectors. These initiatives encompass activities to raise awareness about NCDs, provide treatment options, and focus on preventive measures. By documenting and highlighting these schemes, Kerala’s health-care system and its achievements can serve as a roadmap for the rest of the country, outlining strategies for prevention, monitoring, and therapeutic interventions. It is imperative that other states within India, as well as low- and middle-income countries (LMICs) at large, adopt and adapt the processes and practices established by Kerala to effectively combat the NCDs pandemic. By following this path, the nation and other LMICs can effectively confront the challenges posed by NCDs and work toward improving their populations’ overall health and well-being.","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135008139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation between joint hypermobility and balance in Indian elite gymnasts 印度优秀体操运动员关节过度活动与平衡的关系

Archives of Medicine and Health Sciences Pub Date : 2023-01-01 DOI: 10.4103/amhs.amhs_64_23

Rashmi Kocheta, Rima Musale, Nilesh Andhare

{"title":"Correlation between joint hypermobility and balance in Indian elite gymnasts","authors":"Rashmi Kocheta, Rima Musale, Nilesh Andhare","doi":"10.4103/amhs.amhs_64_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_64_23","url":null,"abstract":"Background and Aim: As gymnast required good flexibility, therefore they are trained accordingly by overstretching and creating overstressed on joints, muscles and tendons which eventually end up in loss of control on joint motion and lead to excessive range of motion. The purpose of this study is to find out the correlation between flexibility of the muscles and balance in young gymnast. Materials and Methods: Total 123 elite gymnast, age group (10-18) years, females and males. Selected using convenient sampling method. Permission was taken from institutional ethical committee for the cross-sectional study design. Demographic data was collected followed by assessment. Stork balance test it is used for static balance and Lower quarter “Y” balance test used for dynamic balance. As well Joint hypermobility was assessed using Beighton 9-point scoring system. Data was processed using the excel (version 16) basic parameters were calculated: arithmetic mean and statistical analysis (Pearson correlation) was used to correlate. Results: 74 gymnasts were selected according to inclusive criteria out of which 75% female (n = 56) and 24% male (n = 18). The data was divided according to gender, and type of sports. Result derived that correlation coefficient between Beighton and stork test and between Beighton and Y balance in females playing rhythmic gymnastics is (r = 0.1) and (r = 0.05), and for males playing artistic gymnastics is (r = -0.23) for both tests. Conclusion: In present study, positive correlation coefficient was found in females playing rhythmic gymnast while negative correlation was found in male playing artistic gymnasts related to hypermobility and balance.","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136373384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges in the management of Buruli ulcer in Nigeria – A case report and literature review 尼日利亚布鲁里溃疡治疗面临的挑战——病例报告和文献综述

Archives of Medicine and Health Sciences Pub Date : 2023-01-01 DOI: 10.4103/amhs.amhs_26_23

O. Ilori, O. Ilori, A. Alabi, S. Adedokun

引用次数: 0

Life lessons from the stock market 股市的人生教训

Archives of Medicine and Health Sciences Pub Date : 2023-01-01 DOI: 10.4103/amhs.amhs_215_23

Anil Kakunje

引用次数: 0

The unseen strain on health-care professionals: Exploring phantom vibration syndrome 医疗保健专业人员看不见的压力:探索振动幻觉综合症

Archives of Medicine and Health Sciences Pub Date : 2023-01-01 DOI: 10.4103/amhs.amhs_92_23

GopalSingh Charan, Charanjit Kaur, Amanpreet Kaur

引用次数: 0

An update on carbapenem resistance in nonfermenting gram-negative bacteria 非发酵革兰氏阴性菌碳青霉烯类耐药研究进展

Archives of Medicine and Health Sciences Pub Date : 2023-01-01 DOI: 10.4103/amhs.amhs_87_23

KV Sreejith, B Arun, VK Anjana, K Sumesh, MohindC Mohan

{"title":"An update on carbapenem resistance in nonfermenting gram-negative bacteria","authors":"KV Sreejith, B Arun, VK Anjana, K Sumesh, MohindC Mohan","doi":"10.4103/amhs.amhs_87_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_87_23","url":null,"abstract":"Antimicrobial resistance is considered one of the most important and severe global public health threats. Carbapenems are the drug of choice that can be employed in treating severe bacterial infections and emergency scenarios caused by multidrug-resistant infections. In the present situation, resistance to carbapenem has emerged as a significant global public health problem due to its complications in hospitalized settings. Carbapenems were once considered the backbone of treating life-threatening infections, but with the emergence of resistance, their utility as a life-saving drug has been compromised. The nonfermenting Gram-negative bacteria (NFGNB) are a group of organisms with the potential to cause difficulties in treating life-threatening infections, often in the cases of immunocompromised patients with multiple preexisting comorbidities. Most of the members in this group are intrinsically resistant to multiple antibiotics and carbapenems are the drug of choice for such infections. However, the rate of carbapenem resistance in NFGNB is gradually increasing worldwide and the need to study the mechanism of carbapenem resistance in nonfermenting Gram-negative bacilli is very important in the combat against multidrug-resistant infections. This review emphasizes the characteristics of the NFGNB, their clinical impact, detection of resistance, and the other applicable treatment strategies.","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135008392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0