{"title":"Evolution of research on the effect of unemployment on acute myocardial infarction risk.","authors":"William T Gallo","doi":"10.1001/jamainternmed.2013.1835","DOIUrl":"https://doi.org/10.1001/jamainternmed.2013.1835","url":null,"abstract":"","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1737-8"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/jamainternmed.2013.1835","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31060182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fasting for lipid testing: is it worth the trouble?: comment on \"fasting time and lipid levels in a community-based population\".","authors":"Amit V Khera, Samia Mora","doi":"10.1001/2013.jamainternmed.263","DOIUrl":"https://doi.org/10.1001/2013.jamainternmed.263","url":null,"abstract":"","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1710-1"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/2013.jamainternmed.263","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31325708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is hypertension overtreatment a silent epidemic?-Reply.","authors":"Eve A Kerr, Timothy P Hofer","doi":"10.1001/2013.jamainternmed.317","DOIUrl":"https://doi.org/10.1001/2013.jamainternmed.317","url":null,"abstract":"","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1769-70"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/2013.jamainternmed.317","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31494958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"About this journal.","authors":"","doi":"10.1001/archinte.172.22.1699","DOIUrl":"https://doi.org/10.1001/archinte.172.22.1699","url":null,"abstract":"","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1699"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31495215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using health information technology to improve health care: emphasizing speed to value.","authors":"Walter H Ettinger","doi":"10.1001/2013.jamainternmed.607","DOIUrl":"https://doi.org/10.1001/2013.jamainternmed.607","url":null,"abstract":"","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1728-30"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/2013.jamainternmed.607","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31327254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Body mass index vs cholesterol in cardiovascular disease risk prediction models.","authors":"David Faeh, Julia Braun, Matthias Bopp","doi":"10.1001/2013.jamainternmed.327","DOIUrl":"https://doi.org/10.1001/2013.jamainternmed.327","url":null,"abstract":"","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1766-8"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/2013.jamainternmed.327","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31234836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acupuncture for dyspnea on exertion in chronic obstructive pulmonary disease: no blindness-reply.","authors":"Masao Suzuki, Naoto Ishizaki","doi":"10.1001/jamainternmed.2013.1285","DOIUrl":"https://doi.org/10.1001/jamainternmed.2013.1285","url":null,"abstract":"","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1772-3"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/jamainternmed.2013.1285","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31588375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Community health workers combat readmission.","authors":"Shreya Kangovi, Judith A Long, Ezekiel Emanuel","doi":"10.1001/2013.jamainternmed.82","DOIUrl":"https://doi.org/10.1001/2013.jamainternmed.82","url":null,"abstract":"","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1756-7"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/2013.jamainternmed.82","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31030288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cost control in a parallel universe: Medicare spending in the United States and Canada.","authors":"David U Himmelstein, Steffie Woolhandler","doi":"10.1001/2013.jamainternmed.272","DOIUrl":"https://doi.org/10.1001/2013.jamainternmed.272","url":null,"abstract":"1. Joint Commission. Improving America’s Hospitals: The Joint Commission Annual Report on Quality and Safety, 2007. http://www.jointcommission .org/Improving_Americas_Hospitals_The_Joint_Commissions_Annual _Report_on_Quality_and_Safety_-_2007/. Accessed September 6, 2012. 2. Cohen MD, Hilligoss PB. The published literature on handoffs in hospitals: deficiencies identified in an extensive review. Qual Saf Health Care. 2010; 19(6):493-497. 3. Arora VM, Johnson JK, Meltzer DO, Humphrey HJ. A theoretical framework and competency-based approach to improving handoffs. Qual Saf Health Care. 2008;17(1):11-14. 4. Horwitz LI, Moin T, Green ML. Development and implementation of an oral sign-out skills curriculum. J Gen Intern Med. 2007;22(10):1470-1474. 5. Riesenberg LA, Leitzsch J, Little BW. Systematic review of handoff mnemonics literature. Am J Med Qual. 2009;24(3):196-204. 6. Hilligoss PB, Cohen MD. Hospital handoffs as multifunctional situated routines: implications for researchers and administrators. In: Blair JD, Fottler M, Savage G, Friedman LH, eds. Biennial Review of Health Care Management (Advances in Health Care Management). Vol 11. Bingley, England: Emerald Group Publishing; 2011:91-132. 7. Manly BFJ. Randomization, Bootstrap and Monte Carlo Methods in Biology. Boca Raton, FL: Chapman & Hall/CRC; 2007. 8. De Leeuw J, Hornik K, Mair P. Isotone optimization in R: pool-adjacentviolators algorithm (PAVA) and active set methods. J Stat Softw. 2009; 32(5):1-24. 9. Robertson T, Wright FT, Dykstra R. Order Restricted Statistical Inference. Chichester, NY: Wiley; 1988. 10. Sanghavi D. The phantom menace of sleep-deprived doctors. New York Times Magazine. 2011. http://www.nytimes.com/2011/08/07/magazine /the-phantom-menace-of-sleep-deprived-doctors.html. Accessed January 15, 2012.","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1764-6"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/2013.jamainternmed.272","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31010752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Li Zhou, Saverio M Maviglia, Lisa M Mahoney, Frank Chang, E John Orav, Joseph Plasek, Laura J Boulware, David W Bates, Roberto A Rocha
{"title":"Supratherapeutic dosing of acetaminophen among hospitalized patients.","authors":"Li Zhou, Saverio M Maviglia, Lisa M Mahoney, Frank Chang, E John Orav, Joseph Plasek, Laura J Boulware, David W Bates, Roberto A Rocha","doi":"10.1001/2013.jamainternmed.438","DOIUrl":"https://doi.org/10.1001/2013.jamainternmed.438","url":null,"abstract":"<p><strong>Background: </strong>We investigated acetaminophen use and identify factors contributing to supratherapeutic dosing of acetaminophen in hospitalized patients.</p><p><strong>Methods: </strong>We retrospectively reviewed the electronic health records of adult patients who were admitted to 2 academic tertiary care hospitals (hospital A amd hospital B) from June 1, 2010, to August 31, 2010, and who received acetaminophen during their hospitalization. Patients' acetaminophen administration records (including drug name, dose, administration time, hospital units, etc), demographic data, diagnoses, and results from liver function tests were obtained. The main outcome measures included acetaminophen exposure rate and supratherapeutic dosing rate among hospitalized patients, hazard ratios (HRs) and 95% confidence intervals (CIs) for risk factors for supratherapeutic dosing, and changes in liver function test before and after supratherapeutic dosing.</p><p><strong>Results: </strong>A total of 14 411 patients (60.7%) were exposed to acetaminophen, of whom 955 (6.6%) exceeded the 4 g per day maximum recommended dose. In addition, 22.3% of patients who were 65 years or older and 17.6% of patients with chronic liver diseases exceeded the recommended limit of 3 g per day. Patients receiving excessive doses of acetaminophen tended to have significant alkaline phosphatase elevations, although causal relationship cannot be concluded. A significantly higher risk of supratherapeutic dosing was observed in hospital A (HR, 1.6 [95% CI, 1.4-1.8]), white patients (HR, 1.5 [95% CI, 1.3-1.7]), patients diagnosed as having osteoarthritis (HR, 1.4 [95% CI, 1.3-1.6]), and those who received scheduled administrations (HR, 16.6 [95% CI, 13.5-20.6]), multiple product formulations (HR, 2.4 [95% CI 2.0-2.9]), or the 500-mg strength formulation (HR, 1.9 [95% CI, 1.5-2.3]). A lower risk was found for pro re nata (as needed) administrations (HR, 0.7 [95% CI, 0.6-0.9]) and in nonsurgical and non–intensive care units (HR, 0.6 [95% CI, 0.5-0.7]).</p><p><strong>Conclusions: </strong>Supratherapeutic dosing of acetaminophen was significantly associated with multiple factors. Interventions to reduce the incidence of some risk factors may prevent supratherapeutic acetaminophen dosing in hospitalized patients.</p>","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1721-8"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/2013.jamainternmed.438","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31232183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}