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microspheres 微球
Archives of internal medicine Pub Date : 2020-04-18 DOI: 10.1002/9783527809080.cataz10754
O. Crosby
{"title":"microspheres","authors":"O. Crosby","doi":"10.1002/9783527809080.cataz10754","DOIUrl":"https://doi.org/10.1002/9783527809080.cataz10754","url":null,"abstract":"","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"147 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50804647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Osmolality. 渗透性。
Archives of internal medicine Pub Date : 2020-02-07 DOI: 10.32388/j11gxv
R. Warhol, A. Eichenholz, R. Mulhausen
{"title":"Osmolality.","authors":"R. Warhol, A. Eichenholz, R. Mulhausen","doi":"10.32388/j11gxv","DOIUrl":"https://doi.org/10.32388/j11gxv","url":null,"abstract":"An understanding of the osmotic physiology and colligative properties of a solution will benefit the emergency physician in proper ordering and interpretation of serum osmolality measurements. Though of use in evaluating disorders of water metabolism, the serum osmolality plays a major role in the Emergency Department evaluation of impaired mental status, especially in alcoholics. A significant discrepancy between calculated and measured values may be the earliest laboratory finding in methanol, ethanol, and ethylene glycol ingestion.","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"116 5 1","pages":"743-9"},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49474925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
GLP-1 Relaxes Rat Coronary Arteries by Enhancing ATP-Sensitive Potassium Channel Currents. GLP-1 通过增强 ATP 敏感性钾通道电流舒张大鼠冠状动脉
IF 1.8
Archives of internal medicine Pub Date : 2019-10-23 eCollection Date: 2019-01-01 DOI: 10.1155/2019/1968785
Qian-Feng Xiong, Shao-Hua Fan, Xue-Wen Li, Yu Niu, Jing Wang, Xin Zhang, Yi-Fan Chen, Ya-Wei Shi, Li-Hui Zhang
{"title":"GLP-1 Relaxes Rat Coronary Arteries by Enhancing ATP-Sensitive Potassium Channel Currents.","authors":"Qian-Feng Xiong, Shao-Hua Fan, Xue-Wen Li, Yu Niu, Jing Wang, Xin Zhang, Yi-Fan Chen, Ya-Wei Shi, Li-Hui Zhang","doi":"10.1155/2019/1968785","DOIUrl":"10.1155/2019/1968785","url":null,"abstract":"<p><p>GLP-1 is a new type of antidiabetic agent that possesses many beneficial effects. Although its cardiovascular actions have been widely examined, little is known about GLP-1's effects on the rat coronary artery (RCA) or about the mechanisms underpinning these effects. Here, we report that GLP-1 inhibits depolarization- or thromboxane receptor agonist (U46619)-induced RCA contraction in a dosage-dependent manner. Vasorelaxation was attenuated by denuding the endothelium, L-NAME (nitric oxide synthase inhibitor), and glyburide (K<sub>ATP</sub> channel blocker) but was not affected by indomethacin (cyclooxygenase inhibitor), iberiotoxin [Ca<sup>2+</sup>-activated K<sup>+</sup> channel (K<sub>Ca</sub>) blocker], or 4-aminopyridine (K<sub>V</sub> channel blocker). Furthermore, GLP-1 increased outward K<sup>+</sup> currents by enhancing the K<sub>ATP</sub> channel in rat coronary arterial smooth muscle cells (RCASMCs). These results show that GLP-1 is an endothelial-dependent vasospasmolytic agent in the RCA and imply that the relaxant effect is regulated by enhancing K<sub>ATP</sub> rather than K<sub>V</sub> or K<sub>Ca</sub> currents in RCASMCs.</p>","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"151 9 1","pages":"1968785"},"PeriodicalIF":1.8,"publicationDate":"2019-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75570403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An automated medical history system. Experience of the Lahey Clinic Foundation with computer-processed medical histories. 一个自动化的病史系统。Lahey诊所基金会计算机处理病史的经验。
Archives of internal medicine Pub Date : 2019-02-03 DOI: 10.1001/archinte.1973.03650090030006
J. Rockart, E. McLean, P. Hershberg, G. O. Bell
{"title":"An automated medical history system. Experience of the Lahey Clinic Foundation with computer-processed medical histories.","authors":"J. Rockart, E. McLean, P. Hershberg, G. O. Bell","doi":"10.1001/archinte.1973.03650090030006","DOIUrl":"https://doi.org/10.1001/archinte.1973.03650090030006","url":null,"abstract":"A mailed questionnaire that can be batch-processed by computer can maintain the editing, formatting, summarizing, and data storage advantages of on-line systems at a lower expense. More than 40,000 patient questionnaires have been processed, and the questionnaire is a routine part of the clinic health care system. Data are given showing increasing physician acceptance and use of the questionnaire. Time savings per patient visit are noted. There are physician-oriented advantages as well as the multiple advantages to the patient when completing the questionnaire in the quiet of his own home.","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"132 3 1","pages":"348-58"},"PeriodicalIF":0.0,"publicationDate":"2019-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archinte.1973.03650090030006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46936932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Electrocardiogram Changes Suggestive of Coronary Artery Disease in Pneumothorax 气胸的心电图改变提示冠状动脉疾病
Archives of internal medicine Pub Date : 2017-01-01 DOI: 10.1001/archinte.1970.00310010153019
R. B. Copeland, G. Omenn
{"title":"Electrocardiogram Changes Suggestive of Coronary Artery Disease in Pneumothorax","authors":"R. B. Copeland, G. Omenn","doi":"10.1001/archinte.1970.00310010153019","DOIUrl":"https://doi.org/10.1001/archinte.1970.00310010153019","url":null,"abstract":"thorax is sought carefully, this diagnosis may be missed on physical examination. In recent months, we have seen several patients with pneumothorax in whom complaints of chest pain and dyspnea, coupled with an abnormal electrocardiogram, raised the diagnostic possibility of myocardial infarction. We wish to draw attention to the ECG abnormalities associated with pneumothorax and to the useful sign of normalization of the ECG when the patient is in the sitting position.","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"105 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archinte.1970.00310010153019","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50615938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The Supreme Court decision: a victory for uninsured patients. 最高法院的裁决:没有保险的病人的胜利。
Archives of internal medicine Pub Date : 2012-12-10 DOI: 10.1001/2013.jamainternmed.117
Michael Hochman, Mitchell H Katz
{"title":"The Supreme Court decision: a victory for uninsured patients.","authors":"Michael Hochman,&nbsp;Mitchell H Katz","doi":"10.1001/2013.jamainternmed.117","DOIUrl":"https://doi.org/10.1001/2013.jamainternmed.117","url":null,"abstract":"","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1703-4"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/2013.jamainternmed.117","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31027677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Is hypertension overtreatment a silent epidemic? 高血压过度治疗是一种无声的流行病吗?
Archives of internal medicine Pub Date : 2012-12-10 DOI: 10.1001/2013.jamainternmed.96
Steven Rosansky
{"title":"Is hypertension overtreatment a silent epidemic?","authors":"Steven Rosansky","doi":"10.1001/2013.jamainternmed.96","DOIUrl":"https://doi.org/10.1001/2013.jamainternmed.96","url":null,"abstract":"","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1769; author reply 1770"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/2013.jamainternmed.96","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31115443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
The burden of hospitalization for atrial fibrillation. 房颤住院的负担。
Archives of internal medicine Pub Date : 2012-12-10 DOI: 10.1001/2013.jamainternmed.93
William H Carter
{"title":"The burden of hospitalization for atrial fibrillation.","authors":"William H Carter","doi":"10.1001/2013.jamainternmed.93","DOIUrl":"https://doi.org/10.1001/2013.jamainternmed.93","url":null,"abstract":"","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1770; author reply 1770"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/2013.jamainternmed.93","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31115444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New evidence for stretching for preventing nocturnal cramps. 新的证据表明伸展运动可以预防夜间痉挛。
Archives of internal medicine Pub Date : 2012-12-10 DOI: 10.1001/2013.jamainternmed.123
Fiona Hawke, Joshua Burns
{"title":"New evidence for stretching for preventing nocturnal cramps.","authors":"Fiona Hawke,&nbsp;Joshua Burns","doi":"10.1001/2013.jamainternmed.123","DOIUrl":"https://doi.org/10.1001/2013.jamainternmed.123","url":null,"abstract":"","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1770-1"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/2013.jamainternmed.123","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31115445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Our failure to curb excessive testing. 我们未能遏制过度测试。
Archives of internal medicine Pub Date : 2012-12-10 DOI: 10.1001/jamainternmed.2013.1780
Jerome P Kassirer, Arnold Milstein
{"title":"Our failure to curb excessive testing.","authors":"Jerome P Kassirer,&nbsp;Arnold Milstein","doi":"10.1001/jamainternmed.2013.1780","DOIUrl":"https://doi.org/10.1001/jamainternmed.2013.1780","url":null,"abstract":"","PeriodicalId":8290,"journal":{"name":"Archives of internal medicine","volume":"172 22","pages":"1751-3"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/jamainternmed.2013.1780","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31234829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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