Annals of Coloproctology最新文献_第8页

Exfoliate cancer cell analysis in rectal cancer surgery: comparison of laparoscopic and transanal total mesorectal excision, a pilot study. 直肠癌手术中的脱落癌细胞分析：腹腔镜和经肛门全直肠系膜切除术的比较，一项试点研究。

IF 3.1

Annals of Coloproctology Pub Date : 2023-12-01 Epub Date: 2023-12-26 DOI: 10.3393/ac.2023.00479.0068

Kiho You, Jung-Ah Hwang, Dae Kyung Sohn, Dong Woon Lee, Sung Sil Park, Kyung Su Han, Chang Won Hong, Bun Kim, Byung Chang Kim, Sung Chan Park, Jae Hwan Oh

{"title":"Exfoliate cancer cell analysis in rectal cancer surgery: comparison of laparoscopic and transanal total mesorectal excision, a pilot study.","authors":"Kiho You, Jung-Ah Hwang, Dae Kyung Sohn, Dong Woon Lee, Sung Sil Park, Kyung Su Han, Chang Won Hong, Bun Kim, Byung Chang Kim, Sung Chan Park, Jae Hwan Oh","doi":"10.3393/ac.2023.00479.0068","DOIUrl":"10.3393/ac.2023.00479.0068","url":null,"abstract":"Purpose: Minimally invasive surgery (MIS) is currently the standard treatment for rectal cancer. However, its limitations include complications and incomplete total mesorectal resection (TME) due to anatomical features and technical difficulties. Transanal TME (TaTME) has been practiced since 2010 to improve this, but there is a risk of local recurrence and intra-abdominal contamination. We aimed to analyze samples obtained through lavage to compare laparoscopic TME (LapTME) and TaTME.Methods: From June 2020 to January 2021, 20 patients with rectal cancer undergoing MIS were consecutively and prospectively recruited. Samples were collected at the start of surgery, immediately after TME, and after irrigation. The samples were analyzed for carcinoembryonic antigen (CEA) and cytokeratin 20 (CK20) through a quantitative real-time polymerase chain reaction. The primary outcome was to compare the detected amounts of CEA and CK20 immediately after TME between the surgical methods.Results: Among the 20 patients, 13 underwent LapTME and 7 underwent TaTME. Tumor location was lower in TaTME (7.3 cm vs. 4.6 cm, P=0.012), and negative mesorectal fascia (MRF) was more in LapTME (76.9% vs. 28.6%, P=0.044). CEA and CK20 levels were high in 3 patients (42.9%) only in TaTME. There was 1 case of T4 with incomplete purse-string suture and 1 case of positive MRF with dissection failure. All patients were followed up for an average of 32.5 months without local recurrence.Conclusion: CEA and CK20 levels were high only in TaTME and were related to tumor factors or intraoperative events. However, whether the detection amount is clinically related to local recurrence remains unclear.","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10781597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139037354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transanal opening of the intersphincteric space (TROPIS): a novel procedure on the horizon to effectively manage high complex anal fistulas 经肛门括约肌间隙开放术(TROPIS):一种有效治疗高度复杂肛瘘的新方法

Annals of Coloproctology Pub Date : 2023-10-24 DOI: 10.3393/ac.2022.01263.0180

Pankaj Garg, Anvesha Mongia

{"title":"Transanal opening of the intersphincteric space (TROPIS): a novel procedure on the horizon to effectively manage high complex anal fistulas","authors":"Pankaj Garg, Anvesha Mongia","doi":"10.3393/ac.2022.01263.0180","DOIUrl":"https://doi.org/10.3393/ac.2022.01263.0180","url":null,"abstract":"Anal fistulas, especially complex and high fistulas, are difficult to manage. The transanal opening of the intersphincteric space (TROPIS) procedure was first described in 2017, and a high success rate of over 90% was reported in high complex fistulas. Since then, more studies and even a meta-analysis have corroborated the high efficacy of this procedure in high fistulas. Conventionally, the main focus was to close the internal (primary) opening for the fistula to heal. However, most complex fistulas have a component of the fistula tract in the intersphincteric plane. This component is like an abscess (sepsis) in a closed space (2 muscle layers). It is a well-known fact that in the presence of sepsis, healing by secondary intention leads to better results than attempting to heal by primary intention. Therefore, TROPIS is the first procedure in which, instead of closing the internal opening, the opening is widened by laying open the fistula tract in the intersphincteric plane so that healing can occur by secondary intention. Although the drainage of high intersphincteric abscesses through the transanal route was described 5 decades ago, the routine utilization of TROPIS for the definitive management of high complex fistulas was first described in 2017. The external anal sphincter (EAS) is completely spared in TROPIS, as the fistula tract on either side of the EAS is managed separatelyâinner (medial) to the EAS by laying open the intersphincteric space and outer (lateral) to the EAS by curettage or excision. Keywords: Rectal fistula; Anal fistula; Fistula in ano; Transanal opening of the intersphincteric space (TROPIS); Ligation of the intersphincteric tract","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135219422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immune checkpoint therapy in colorectal cancer: is first better than last? 免疫检查点治疗结直肠癌癌症：首次优于最后一次？

IF 3.1

Annals of Coloproctology Pub Date : 2023-10-01 Epub Date: 2023-10-04 DOI: 10.3393/ac.2023.00248.0035

Yui Kaneko, Zainab Naseem, Neil Strugnell, Frances Barnett, Basil D'Souza, Ankur Sidhu, Andrew Bui, Toan Pham

引用次数: 0

Prognostic significance of lymph node yield on oncologic outcomes according to tumor response after preoperative chemoradiotherapy in rectal cancer patients. 直肠癌患者术前放化疗后肿瘤反应对肿瘤预后的影响。

IF 3.1

Annals of Coloproctology Pub Date : 2023-10-01 Epub Date: 2022-04-28 DOI: 10.3393/ac.2022.00143.0020

Hyo Seon Ryu, In Ja Park, Bo Kyung Ahn, Min Young Park, Min Sung Kim, Young Il Kim, Seok-Byung Lim, Jin Cheon Kim

{"title":"Prognostic significance of lymph node yield on oncologic outcomes according to tumor response after preoperative chemoradiotherapy in rectal cancer patients.","authors":"Hyo Seon Ryu, In Ja Park, Bo Kyung Ahn, Min Young Park, Min Sung Kim, Young Il Kim, Seok-Byung Lim, Jin Cheon Kim","doi":"10.3393/ac.2022.00143.0020","DOIUrl":"10.3393/ac.2022.00143.0020","url":null,"abstract":"Purpose: This study aimed to evaluate the predictive value of lymph node yield (LNY) for survival outcomes according to tumor response after preoperative chemoradiotherapy (PCRT) in patients with rectal cancer.Methods: This study was a retrospective study conducted in a tertiary center. A total of 1,240 patients with clinical stage II or III rectal cancer who underwent curative resection after PCRT between 2007 and 2016 were included. Patients were categorized into the good response group (tumor regression grade [TRG], 0-1) or poor response group (TRG, 2-3). Propensity score matching was performed for age, sex, and pathologic stage between LNY of ≥12 and LNY of <12 within tumor response group. The primary outcome was 5-year disease-free survival (DFS) and overall survival (OS).Results: LNY and positive lymph nodes were inversely correlated with TRG. In good responders, 5-year DFS and 5-year OS of patients with LNY of <12 were better than those with LNY of ≥12, but there was no statistical significance. In poor responders, the LNY of <12 group had worse survival outcomes than the LNY of ≥12 group, but there was also no statistical significance. LNY of ≥12 was not associated with DFS and OS in multivariate analysis.Conclusion: LNY of <12 showed contrasting outcomes between the good and poor responders in 5-year DFS and OS. LNY of 12 may not imply adequate oncologic surgery or proper staging in rectal cancer patients treated by PCRT. Furthermore, a decrease in LNY should be comprehended differently according to tumor response.","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45177991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Outcomes following anastomotic leak from rectal resections, including bowel function and quality of life. 直肠切除术吻合口漏后的结果，包括肠功能和生活质量。

IF 3.1

Annals of Coloproctology Pub Date : 2023-10-01 Epub Date: 2022-04-14 DOI: 10.3393/ac.2022.00073.0010

Angelina Di Re, Salam Tooza, Jason Diab, Charbel Karam, Mina Sarofim, Kevin Ooi, Catherine Turner, Daniel Kozman, David Blomberg, Matthew Morgan

{"title":"Outcomes following anastomotic leak from rectal resections, including bowel function and quality of life.","authors":"Angelina Di Re, Salam Tooza, Jason Diab, Charbel Karam, Mina Sarofim, Kevin Ooi, Catherine Turner, Daniel Kozman, David Blomberg, Matthew Morgan","doi":"10.3393/ac.2022.00073.0010","DOIUrl":"10.3393/ac.2022.00073.0010","url":null,"abstract":"Purpose: Anastomotic leak (AL) is an uncommon but potentially devastating complication after rectal resection. We aim to provide an updated assessment of bowel function and quality of life after AL, as well as associated short- and long-term outcomes.Methods: A retrospective audit of all rectal resections performed at a colorectal unit and associated private hospitals over the past 10 years was performed. Relevant demographic, operative, and histopathological data were collected. A prospective survey was performed regarding patients' quality of life and fecal continence. These patients were matched with nonAL patients who completed the same survey.Results: One hundred patients (out of 1,394 resections) were included. AL was contained in 66.0%, not contained in 10.0%, and only anastomotic stricture in 24.0%. Management was antibiotics only in 39.0%, percutaneous drainage in 9.0%, operative abdominal drainage in 19.0%, transrectal drainage in 6.0%, combination of percutaneous drainage and transrectal drainage in 2.0%, and combination abdominal/transrectal drainage in 1.0%. The 1-year stoma rate was 15.0%. Overall, mean Fecal Incontinence Severity Instrument scores were higher for AL patients than their matched counterparts (8.06±10.5 vs. 2.92±4.92, P=0.002). Patients with an AL had a mean EuroQol visual analogue scale (EQ-VAS) of 76.23±19.85; this was lower than the matched mean EQ-VAS for non-AL patients of 81.64±18.07, although not statistically significant (P=0.180).Conclusion: The majority of AL patients in this study were managed with antibiotics only. AL was associated with higher fecal incontinence scores in the long-term; however, this did not equate to lower quality of life scores.","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45164707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk factors associated with low anterior resection syndrome: a cross-sectional study. 与低位前切除综合征相关的危险因素：一项横断面研究。

IF 3.1

Annals of Coloproctology Pub Date : 2023-10-01 Epub Date: 2022-06-03 DOI: 10.3393/ac.2022.00227.0032

Lim See Liang, Wan Zainira Wan Zain, Zalina Zahari, Andee Dzulkarnaen Zakaria, Mohd Nizam Md Hashim, Michael Pak-Kai Wong, Zaidi Zakaria, Rosnelifaizur Ramely, Ahmad Shanwani Mohamed Sidek

{"title":"Risk factors associated with low anterior resection syndrome: a cross-sectional study.","authors":"Lim See Liang, Wan Zainira Wan Zain, Zalina Zahari, Andee Dzulkarnaen Zakaria, Mohd Nizam Md Hashim, Michael Pak-Kai Wong, Zaidi Zakaria, Rosnelifaizur Ramely, Ahmad Shanwani Mohamed Sidek","doi":"10.3393/ac.2022.00227.0032","DOIUrl":"10.3393/ac.2022.00227.0032","url":null,"abstract":"Purpose: Oncological outcomes following rectal cancer surgery have improved significantly over recent decades with lower recurrences and longer overall survival. However, many of the patients experienced low anterior resection syndrome (LARS). This study identified the prevalence and risk factors associated with the development of LARS.Methods: This cross-sectional study involved patients who were diagnosed with rectal cancer and had undergone sphincter-preserving low anterior resection from January 2011 to December 2020. Upon clinic follow-up, patients were asked to complete an interviewed based questionnaire (LARS score) designed to assess bowel dysfunction after rectal cancer surgery.Results: Out of 76 patients, 25 patients (32.9%) had major LARS, 10 patients (13.2%) had minor LARS, and 41 patients (53.9%) had no LARS. The height of tumor from anal verge showed an association with the development of major LARS (P=0.039). Those patients with less than 8 cm tumor from anal verge had an increased risk of LARS by 3 times compared to those with 8 cm and above (adjusted odds ratio, 3.11; 95% confidence interval, 1.06-9.13).Conclusion: Results from our study show that low tumor height was a significant risk factor that has a negative impact on bowel function after surgery. The high prevalence of LARS emphasizes the need for study regarding risk factors and the importance of understanding the pathophysiology of LARS, in order for us to improve patient bowel function and quality of life after rectal cancer surgery.","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47459517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Validation of low anterior resection syndrome score in Brazil with Portuguese. 葡萄牙语对巴西低前切除术综合征评分的验证。

IF 3.1

Annals of Coloproctology Pub Date : 2023-10-01 Epub Date: 2022-05-13 DOI: 10.3393/ac.2022.00136.0019

Kelly C L R Buzatti, Andy Petroianu, Søren Laurberg, Rodrigo G Silva, Beatriz D S Rodrigues, Peter Christensen, Antonio Lacerda-Filho, Therese Juul

{"title":"Validation of low anterior resection syndrome score in Brazil with Portuguese.","authors":"Kelly C L R Buzatti, Andy Petroianu, Søren Laurberg, Rodrigo G Silva, Beatriz D S Rodrigues, Peter Christensen, Antonio Lacerda-Filho, Therese Juul","doi":"10.3393/ac.2022.00136.0019","DOIUrl":"10.3393/ac.2022.00136.0019","url":null,"abstract":"Purpose: This study was performed to investigate the convergent validity, discriminative validity, and reliability of the Brazilian version of the low anterior resection syndrome (LARS) score in a population with low educational and socioeconomic levels.Methods: The LARS score was translated into the Portuguese language by forward- and back-translation procedures. In total, 127 patients from a public hospital in Brazil completed the questionnaires. The convergent validity was tested by comparing the LARS score with the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core Module 30 (QLQ-C30) and with patients' self-reported quality of life. For the discriminative validity, we tested the ability of the score to differentiate among subgroups of patients regarding neoadjuvant radiotherapy, type of surgery, and tumor distance from the anal verge. The test-retest reliability was investigated in a subgroup of 36 patients who responded to the survey twice in 2 weeks.Results: The LARS score demonstrated a strong correlation with 5 of 6 items from the EORTC QLQ-C30 (P<0.05) and good concordance with patients' self-reported quality of life (95.3%), confirming the convergent validity. The score was able to discriminate between subgroups of patients with different clinical characteristics related to LARS (P<0.001). The agreement between the test and retest showed that 86.1% of the patients remained in the same LARS category, and there was no significant difference between the LARS score numerical values (P=0.80), indicating good reliability overall.Conclusion: The Brazilian version of the LARS score is a valid and reliable instrument to assess postoperative bowel function in a population with low educational and socioeconomic levels.","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47003631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The imitation game: a review of the use of artificial intelligence in colonoscopy, and endoscopists' perceptions thereof. 模仿游戏：人工智能在结肠镜检查中的应用综述，以及内镜医生对此的看法。

IF 3.1

Annals of Coloproctology Pub Date : 2023-10-01 Epub Date: 2023-03-10 DOI: 10.3393/ac.2022.00878.0125

Sarah Tham, Frederick H Koh, Jasmine Ladlad, Koy-Min Chue, Cui-Li Lin, Eng-Kiong Teo, Fung-Joon Foo

引用次数: 0

Successful detection and removal of predictable juvenile polyp: a case report. 成功检测和切除可预测的青少年息肉：一例报告。

IF 3.1

Annals of Coloproctology Pub Date : 2023-10-01 Epub Date: 2021-07-21 DOI: 10.3393/ac.2021.00311.0044

Kwang Yeon Kim, Jin Su Kim

引用次数: 1

Comments on "Laser hemorrhoidoplasty versus conventional hemorrhoidectomy for grade II/III hemorrhoids: a systematic review and meta-analysis". 关于“激光痔疮成形术与传统痔疮切除术治疗Ⅱ/Ⅲ级痔疮：系统综述和荟萃分析”的评论。

IF 3.1

Annals of Coloproctology Pub Date : 2023-10-01 Epub Date: 2023-10-30 DOI: 10.3393/ac.2023.00206.0029

Mohamed Ali Chaouch, Amine Gouader, Bassem Krimi, Hani Oweira

引用次数: 0