Archives of dermatology最新文献_第10页

Umbilical endometriosis with urachal remnant. 脐带子宫内膜异位症伴尿管残留。

Archives of dermatology Pub Date : 2012-11-01 DOI: 10.1001/archdermatol.2012.1983

Takehito Mizutani, Yoshiaki Sakamoto, Hiroko Ochiai, Arafumi Maeshima

引用次数: 9

Archives of dermatology Pub Date : 2012-11-01 DOI: 10.1001/archdermatol.2012.2705

Andreas Blum, Giuseppe Argenziano, Jonathan Bowling, Jason Giacomel, Rainer Hofmann-Wellenhof, Jurgen Kreusch, Iris Zalaudek, James Grichnik

引用次数: 0

High prevalence of stump dermatoses 38 years or more after amputation. 截肢后38年或更长时间残肢皮肤病高发。

Archives of dermatology Pub Date : 2012-11-01 DOI: 10.1001/archdermatol.2012.3004

Nicole B Yang, Luis A Garza, Carrie E Foote, Sewon Kang, Jon H Meyerle

{"title":"High prevalence of stump dermatoses 38 years or more after amputation.","authors":"Nicole B Yang, Luis A Garza, Carrie E Foote, Sewon Kang, Jon H Meyerle","doi":"10.1001/archdermatol.2012.3004","DOIUrl":"https://doi.org/10.1001/archdermatol.2012.3004","url":null,"abstract":"Objective: To highlight the prevalence and impact of skin disease at the stump site in patients who have undergone amputation.Design: A cross-sectional health questionnaire of Vietnam War veterans with stump dermatoses at least 38 years after major limb amputation.Setting: A research registry of veterans with combat-related amputations who agreed to participate.Participants: Recruitment began January 1, 2006, and ended December 31, 2009, with a registry of 416 veterans.Main outcome measures: Results of a self-reported 35-item questionnaire. Participants were later contacted by telephone or asked to complete a Web survey.Results: Of the 247 veterans, 119 (48.2%) reported at least 1 skin problem within the preceding year. The most common were skin breakdown (25.2%), rash (21.8%), and abrasion (21.0%). In addition, 25.2% experienced skin problems more than 50% of the time, and 37.1% had to alter or replace their prosthesis. Stump dermatoses limited or prevented prosthesis use in the preceding year for 55.6% and caused pain or discomfort at the stump site in 61.5%.Conclusions: More than 38 years after major limb amputation, skin complications at the stump site continue to cause significant morbidities and contribute to prosthesis abandonment. The high prevalence of stump dermatoses stresses the importance of disease prevention, early management, and advanced treatment of skin disease.","PeriodicalId":8175,"journal":{"name":"Archives of dermatology","volume":"148 11","pages":"1283-6"},"PeriodicalIF":0.0,"publicationDate":"2012-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archdermatol.2012.3004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31060764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

The genocide of individuals with albinism in Africa. 非洲对白化病患者的种族灭绝。

Archives of dermatology Pub Date : 2012-10-01 DOI: 10.1001/archdermatol.2012.2515

Barry Ladizinski, Andres E Cruz-Inigo, Aisha Sethi

引用次数: 1

Golimumab-exacerbated subacute cutaneous lupus erythematosus. 戈利单抗加重亚急性皮肤红斑狼疮。

Archives of dermatology Pub Date : 2012-10-01 DOI: 10.1001/archdermatol.2012.1856

Eric Wilkerson, Matthew A Hazey, Soon Bahrami, Jeffrey P Callen

{"title":"Golimumab-exacerbated subacute cutaneous lupus erythematosus.","authors":"Eric Wilkerson, Matthew A Hazey, Soon Bahrami, Jeffrey P Callen","doi":"10.1001/archdermatol.2012.1856","DOIUrl":"https://doi.org/10.1001/archdermatol.2012.1856","url":null,"abstract":"Background: Subacute cutaneous lupus erythematosus (SCLE) is characterized by annular, nonscarring, photodistributed, or papulosquamous lesions. The disease may be idiopathic, drug induced, or drug exacerbated.Observations: A 66-year-old woman with a history of hypertension, parkinsonism, rheumatoid arthritis, anxiety and depression, and symptoms of Sjögren syndrome was seen with a 1-month history of an eruption on her upper extremities and upper trunk. The eruption had begun 2 to 3 weeks after subcutaneous injection of golimumab for rheumatoid arthritis. She had developed SCLE 2 years previously due to furosemide use and 10 years previously due to hydrochlorothiazide use. Physical examination revealed scaly, annular, erythematous plaques photodistributed on the arms, legs, and upper trunk. A punch biopsy specimen demonstrated vacuolar interface dermatitis and lymphohistiocytic perivascular inflammation. Serological abnormalities included a positive antinuclear antibody, an elevated anti-La/SS-B antibody level, and an elevated anti-Ro/SS-A antibody level. She was diagnosed as having SCLE and was initially treated with desonide lotion, photoprotection, prednisone (40 mg/d) tapered over 6 weeks, and hydroxychloroquine sulfate (200 mg twice daily). Because of persistent disease, methotrexate sodium (12.5 mg/wk) was subsequently added to the regimen, and her eruption cleared completely.Conclusions: Golimumab should be added to the list of medications capable of inducing or exacerbating SCLE. Our patient demonstrated variable times to the resolution of SCLE, possibly attributable in part to the different half-lives of the agents administered.","PeriodicalId":8175,"journal":{"name":"Archives of dermatology","volume":"148 10","pages":"1186-90"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archdermatol.2012.1856","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30981001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 23

Dynamic changes in nevi of a patient with melanoma treated with vemurafenib: importance of sequential dermoscopy. vemurafenib治疗黑色素瘤患者的动态变化:顺序皮肤镜检查的重要性。

Archives of dermatology Pub Date : 2012-10-01 DOI: 10.1001/archdermatol.2012.2649

Holger A Haenssle, Sophie L Kraus, Franziska Brehmer, Lutz Kretschmer, Bernward Völker, Hiba Asper, Alexander Kapp, Ralf Gutzmer

{"title":"Dynamic changes in nevi of a patient with melanoma treated with vemurafenib: importance of sequential dermoscopy.","authors":"Holger A Haenssle, Sophie L Kraus, Franziska Brehmer, Lutz Kretschmer, Bernward Völker, Hiba Asper, Alexander Kapp, Ralf Gutzmer","doi":"10.1001/archdermatol.2012.2649","DOIUrl":"https://doi.org/10.1001/archdermatol.2012.2649","url":null,"abstract":"BACKGROUND Therapy with vemurafenib, an inhibitor of mutated BRAF, yields a response rate of approximately 50% in patients with metastatic melanoma harboring a BRAF V600E mutation. As an adverse effect of vemurafenib, proliferative disorders of keratinocytes, including squamous cell carcinoma, have been described. Low concentration of vemurafenib as present in the epidermis were found to activate wild-type RAF, which, in combination with a preexisting RAS mutation, can promote keratinocyte proliferation. While activating BRAF mutations occur in approximately 50% of melanomas, they are even more frequently observed in melanocytic nevi. OBSERVATION We present the case of a patient with dynamic changes of melanocytic nevi well documented by sequential digital dermoscopy during vemurafenib therapy. A variety of dermoscopic changes were observed. First, nevi involuted, and all of these originally showed a centrally elevated papillomatous and predominant globular pattern. Second, preexisting nevi increased in size, and pigmentation that rendered them atypical. Such lesions were flat and showed a predominant reticular pattern at baseline. Third, multiple new nevi occurred. One example of each of the latter 2 categories was excised and showed wild-type BRAF. CONCLUSION Our findings of changing nevi in a patient treated with vemurafenib highlight the need for sequential skin examinations, including dermoscopy.","PeriodicalId":8175,"journal":{"name":"Archives of dermatology","volume":"148 10","pages":"1183-5"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archdermatol.2012.2649","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30849424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 61

Diffuse hyperkeratosis in a deaf and blind 48-year-old woman-diagnosis. 弥漫性角化过度症1例聋盲48岁女性。

Archives of dermatology Pub Date : 2012-10-01 DOI: 10.1001/archderm.148.10.1200-c

引用次数: 0

The heliotrope sign of dermatomyositis: the correct meaning of the term heliotrope. 皮肌炎的日光征:日光征一词的正确含义。

Archives of dermatology Pub Date : 2012-10-01 DOI: 10.1001/archdermatol.2012.2596

Terresa Russo, Vincenzo Piccolo, Eleonora Ruocco, Adone Baroni

引用次数: 9

Erythematous eruption with marked conjunctival injection--quiz case. Diagnosis: leukemia cutis with conjunctival involvement in the setting of T-cell prolymphocytic leukemia (T-PLL). 红斑疹伴明显结膜注射——测试病例。诊断:t细胞前淋巴细胞白血病(T-PLL)伴结膜受累的皮肤白血病。

Archives of dermatology Pub Date : 2012-10-01 DOI: 10.1001/archderm.148.10.1199-d

Edidiong Celestine Ntuen Kaminska, Zoey Yu, John Kress, Vesna Petronic-Rosic, Keyoumars Soltani

引用次数: 3

Sufficiency and safety of 2-cm excision margin for stage IIA through stage IIC cutaneous melanoma. 2厘米切缘治疗IIA期至IIC期皮肤黑色素瘤的充分性和安全性。

Archives of dermatology Pub Date : 2012-10-01 DOI: 10.1001/archdermatol.2012.2682

Michael J Sladden

引用次数: 0